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https://www.readbyqxmd.com/read/29169050/utility-of-post-mortem-computed-tomography-in-clivus-fracture-diagnosis-case-illustration-and-literature-review
#1
S Zerbo, A Di Piazza, G Lo Re, G L Aronica, S Salerno, R Lagalla
Clivus fractures are usually associated with head blunt trauma due to traffic accident and falls. A 23 - year-old man died immediately after a smash-up while he was stopping on his motorcycle. Post-mortem Computed tomography (PMCT), performed before autopsy, revealed a complex basilar skull base fractures associated with brainstem and cranio-vertebral junction injuries, improving the diagnostic performance of conventional autopsy. Imaging data were re-assessable and PMCT offers the possibility to perform multiplanar and volume rendered reconstructions, increasing forensic medicine knowledge related to traumatic injuries...
November 16, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29168784/optimization-of-the-use-of-his%C3%A2-oph-based-enzymatic-biocatalysts-for-the-destruction-of-chlorpyrifos-in-soil
#2
Olga Senko, Olga Maslova, Elena Efremenko
Applying enzymatic biocatalysts based on hexahistidine-containing organophosphorus hydrolase (His₆-OPH) is suggested for the decomposition of chlorpyrifos, which is actively used in agriculture in many countries. The application conditions were optimized and the following techniques was suggested to ensure the highest efficiency of the enzyme: first, the soil is alkalinized with hydrated calcitic lime Ca(OH)₂, then the enzyme is introduced into the soil at a concentration of 1000 U/kg soil. Non-equilibrium low temperature plasma (NELTP)-modified zeolite is used for immobilization of the relatively inexpensive polyelectrolyte complexes containing the enzyme His₆-OPH and a polyanionic polymer: poly-l-glutamic acid (PLE50) or poly-l-aspartic acid (PLD50)...
November 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29168669/awake-craniotomy-versus-craniotomy-under-general-anesthesia-for-the-surgical-treatment-of-insular-glioma-choices-and-outcomes
#3
B Y Gravesteijn, M E Keizer, A J P E Vincent, J W Schouten, R J Stolker, M Klimek
OBJECTIVE: To investigate differences in outcomes in patients who underwent surgery for insular glioma using an awake craniotomy (AC) vs. a craniotomy under general anesthesia (GA). METHODS: Data from patients treated at our hospital between 2005 and 2015 were analyzed retrospectively. The preoperative, intraoperative, postoperative, and longer term follow-up characteristics and outcomes of patients who underwent surgery for primary insular glioma using either an AC or GA were compared...
November 23, 2017: Neurological Research
https://www.readbyqxmd.com/read/29168653/utilizing-biomarkers-in-colorectal-cancer-an-interview-with-ajay-goel
#4
Ajay Goel
Ajay Goel, PhD, is a Professor and Director, Center for Gastrointestinal Research, and Director, Center for Translational Genomics and Oncology, at the Baylor Scott & White Research Institute, Baylor University Medical Center in Dallas, Texas. Dr Goel has spent more than 20 years researching cancer and has been the lead author or contributor to over 240 scientific articles published in peer-reviewed international journals and several book chapters. He is also a primary inventor on more than 15 international patents aimed at developing various biomarkers for the diagnosis, prognosis and prediction of gastrointestinal cancers...
November 23, 2017: Future Oncology
https://www.readbyqxmd.com/read/29168622/mitral-valve-pressure-gradient-after-percutaneous-mitral-valve-repair-every-beat-counts
#5
Daniel Lavall, Bruno Scheller, Christian Werner, Axel Buob, Felix Mahfoud
A patient presented with symptoms of decompensated heart failure 2 months after percutaneous mitral valve (MV) repair. Echocardiography demonstrated impaired left ventricular function with elevated MV pressure gradients and pulmonary pressures during rapid atrial fibrillation. Heart rate control was achieved by implantation of a biventricular pacemaker with subsequent His-bundle ablation because atrial fibrillation was refractory to medical treatment. During biventricular pacing at different rates (50-110 b...
November 23, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29168584/hemolysis-and-iga-antibodies-against-tissue-transglutaminase-when-are-antibody-test-results-no-longer-reliable
#6
Johannes Wolf, Norman Haendel, Johannes Remmler, Carl Elias Kutzner, Thorsten Kaiser, Thomas Mothes
BACKGROUND: Antibodies against tissue transglutaminase (TTG) of isotype IgA (IgA-aTTG) represent reliable diagnostic markers to confirm or exclude celiac disease (CD). Hemolysis (HL) is an important pre-analytical factor. HL can be quantified as HL index (HI) correlating with the concentration of free hemoglobin. TTG is abundant in erythrocytes and released upon HL. In immunoassays, the released TTG may interfere with binding of IgA-aTTG to the coated TTG. METHODS: We selected 17 HL-free sera from children with biopsy-confirmed CD: 7 with low-positive (1-5 multiples of upper limit of normal [×ULN]), 5 with intermediate (5-10 × ULN) and 5 with high IgA-aTTG (10-15 × ULN)...
November 23, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29168116/reference-to-self-and-other-in-the-digital-public-sphere-the-case-of-political-blogs
#7
Barbara De Cock, Cristian González Arias
In this paper, we analyze how a political blog author (Spanish Alejo Vidal-Quadras) establishes the reference to self and other in his blog entries. We furthermore look into how the commentators to this blog react and establish reference to self and other in the digital public sphere. More concretely, we show that they not only take up the references established by the main blog author but also create new references. These allow, on the one hand, for profiling themselves as part of a group and, on the other hand, identifying their interlocutor among the variety of possible interlocutors in the digital public sphere...
November 22, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/29168089/brief-report-investigating-relations-between-self-concept-and-performance-in-reading-and-math-for-school-aged-children-and-adolescents-with-autism-spectrum-disorder
#8
James B McCauley, Matthew C Zajic, Tasha M Oswald, Lindsey E Swain-Lerro, Nancy C McIntyre, Michelle A Harris, Kali Trzesniewski, Peter C Mundy, Marjorie Solomon
A typically developing student's perceptions of his or her own capabilities (academic self-concept), is predictive of later academic achievement. However, little is known about academic self-concept in youth with autism spectrum disorder (ASD). To understand whether students math self-concept and reading self-concept predicted their performance, 44 school-aged children and adolescents with ASD and 36 age-matched individuals with typical development (TYP) rated their perceived math and reading abilities and were administered standardized achievement measures...
November 22, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29168074/paleoanthropology-s-uses-of-the-bipedal-criterion
#9
Mathilde Lequin
Bipedalism is one of the criteria that paleoanthropologists use in order to interpret the fossil record and to determine if a specimen belongs to the human lineage. In the context of such interpretations, bipedalism is considered to be a unique characteristic of this lineage that also marks its origin. This conception has largely remained unchallenged over the last decades, in spite of fossil discoveries that led to the emergence of bipedalism in the human lineage being shifted back by several millions of years...
November 22, 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/29167625/from-cubist-simultaneity-to-quantum-complementarity
#10
Christophe Schinckus
This article offers a contribution to the history of scientific ideas by proposing an epistemological argument supporting the assumption made by Miller whereby Niels Bohr has been influenced by cubism (Jean Metzinger) when he developed his non-intuitive complementarity principle. More specifically, this essay will identify the Bergsonian durée as the conceptual bridge between Metzinger and Bohr. Beyond this conceptual link between the painter and the physicist, this paper aims to emphasize the key role played by art in the development of human knowledge...
2017: Foundations of Science
https://www.readbyqxmd.com/read/29167624/unique-ventricular-tachycardia-originating-from-the-right-bundle-branch
#11
Hongliang Yang, Daoyuan Si, Yaliang Tong, Zhe An, Ping Yang, Yuquan He
Ventricular tachycardia (VT), a common arrhythmia, frequently originates from in the right ventricular outflow tract, left ventricular outflow tract, aortic sinus, and left ventricular papillary muscle but infrequently from the His-Purkinje system, whereas the VT stemming from the right bundle branch has rarely been reported. Here we reported a case with of VT originating from the right bundle branch which was subsequently successfully treated with radiofrequency ablation and demonstrated the electrocardiac features of VT using an electrophysiological examination...
November 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29167554/phenotypic-expression-of-a-novel-desmin-gene-mutation-hypertrophic-cardiomyopathy-followed-by-systemic-myopathy
#12
Haruhito Harada, Takeharu Hayashi, Hirofumi Nishi, Ken Kusaba, Yoshinori Koga, Yasutoshi Koga, Ikuya Nonaka, Akinori Kimura
Hypertrophic cardiomyopathy is a heterogeneous disease caused by gene mutations. Most of the disease-causing mutations were found in the genes for sarcomeric proteins, but there are several cases carrying mutations in genes for extra-sarcomeric cytoskeletons. Desmin is a member of extra-sarcomeric cytoskeletons and plays an important role in muscle contraction. Mutations in the desmin gene cause various type of general myopathy and/or cardiomyopathy, known as desmin-related myopathies. We identified a novel desmin missense mutation, Thr219Pro, in the homozygous state in a patient, who first manifested with hypertrophic cardiomyopathy and later progressed to general myopathy...
November 22, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/29167415/ticagrelor-leads-to-statin-induced-rhabdomyolysis-a-case-report
#13
Simone M Mrotzek, Tienush Rassaf, Matthias Totzeck
BACKGROUND Following acute coronary intervention in cardiology patients, the combined medical therapy with the platelet inhibitory drug ticagrelor and a statin medication (e.g., simvastatin) is recommended according to international guidelines. Yet combined therapeutic regimens have the potential of pharmacological interaction with both ticagrelor and simvastatin being metabolized by CYP3A4. Rhabdomyolysis is a known side-effect of statin therapy and combined therapy increases the susceptibility to this complication...
November 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29167185/hyperacute-leucopenia-associated-with-furosemide
#14
Ben-Jiang Ma
A 72-year-old man presented to the hospital with exacerbation of congestive heart failure. He was given furosemide 40 mg intravenously twice at 4 hours apart. At 4 hours after the second dose of furosemide, his white blood cells (WBC) dropped acutely from 9.8 to 2.4×10(9)/L (reference range 4.1 to 9.3×10(9)/L). With the discontinuation of furosemide, the WBC trended up to 7.1×10(9)/L about 13 hours after the second dose of intravenous furosemide and remained in normal range for the next 3 days. However, when the oral furosemide was started on hospital day 4, there was a mild drop in WBC count, which returned to and maintained at baseline since the next day...
November 21, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29167158/observations-on-bipolar-disjunctions-of-moonwort-ferns-botrychium-ophioglossaceae
#15
Donald R Farrar, Mary C Stensvold
Peter Raven, in 1963, included two fern taxa of the genus Botrychium in his list of plant species exhibiting American amphitropical bipolar disjunctions. He attributed the southern hemisphere occurrences to post-Pleistocene long-distance dispersal from counterparts in the northern hemisphere, probably assisted by annual bird migrations between the disjunct areas. Using genetic evidence gathered through worldwide analyses of phylogenetic relationship in Botrychium, we now review and reconsider Raven's conclusions...
November 22, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/29166986/a-retrospective-assessment-of-return-to-function-in-dance-after-physical-therapy-for-common-dance-injuries
#16
Emily Junck, Megan Richardson, Faye Dilgen, Marijeanne Liederbach
An injury that causes a dancer to take time away from training or performance can be career ending, and thus it is important for dancers to have accurate expectations when considering treatment options. Thus far, few studies have reported functional outcomes after injury in dancers, which may be different than for the general athletic population. Therefore, our study sought to determine functional outcomes in dancers after operative and non-operative treatment for common dance injuries. Our outcome measures included a subjective assessment of the degree to which a dancer had returned to his or her previous level of dance, the SF-12 survey, and the WHO functional outcome scale modified for dance...
December 15, 2017: Journal of Dance Medicine & Science
https://www.readbyqxmd.com/read/29166922/herpes-simplex-type-1-pneumonitis-and-acute-respiratory-distress-syndrome-in-a-patient-with-chronic-lymphatic-leukemia-a-case-report
#17
Miriam Luginbuehl, Alexander Imhof, Alexander Klarer
BACKGROUND: Pulmonary pathogenicity of herpes simplex virus type 1 in patients in intensive care without classic immunosuppression as well as the necessity of antiviral treatment in the case of herpes simplex virus detection in respiratory specimens in these patients is controversial. We present a case of acute respiratory distress syndrome in a patient with stable chronic lymphatic leukemia not requiring treatment, in whom we diagnosed herpes simplex virus type 1 bronchopneumonitis based on herpes simplex virus type 1 detection in bronchoalveolar lavage fluid and clinical response to antiviral treatment...
November 23, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29166856/glycyl-alanyl-histidine-protects-pc12-cells-against-hydrogen-peroxide-toxicity
#18
Hideki Shimura, Ryota Tanaka, Yoshiaki Shimada, Kazuo Yamashiro, Nobutaka Hattori, Takao Urabe
BACKGROUND: Peptides with cytoprotective functions, including antioxidants and anti-infectives, could be useful therapeutics. Carnosine, β-alanine-histidine, is a dipeptide with anti-oxidant properties. Tripeptides of Ala-His-Lys, Pro-His-His, or Tyr-His-Tyr are also of interest in this respect. RESULTS: We synthesized several histidine-containing peptides including glycine or alanine, and tested their cytoprotective effects on hydrogen peroxide toxicity for PC12 cells...
November 22, 2017: BMC Biochemistry
https://www.readbyqxmd.com/read/29166691/-emil-kraepelin-s-time-in-dorpat-did-this-stay-made-marks-in-russian-and-soviet-psychiatry
#19
Birk Engmann, Holger Steinberg
In Russia, German psychiatrist Emil Kraepelin (1856-1926) is regarded as an influential and famous personality in the history of the field. This study discusses whether it was his period in the Russian Empire in the years 1886 to 1891 when he worked at Dorpat University (today Tartu, Estonia) that raised his popularity in Russia. Our research shows that all of his writings which had been translated into Russian language derive from a period much later than Dorpat. Moreover, none of his students has ever reached a scientific position which would have enabled him to become a proponent of Kraepelin's ideas in Russia...
November 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29166539/an-unusual-cause-of-headache-and-sudden-death-of-a-young-sailor-postmortem-computed-tomography-and-histological-findings-of-a-fatal-retroperitoneal-malignant-mixed-germ-cell-tumor
#20
Belinda Lee, Michelle Chan, Ronald Goh
A 26-year-old Caucasian sailor, with no past medical history aside from headache for the last 1 week, was found dead in his cabin. The body was stored in a refrigerator on board and disembarked for autopsy 3 days later. Autopsy showed a large, nodular, necrotic and hemorrhagic retroperitoneal mass, and smaller hemorrhagic nodules in the brain, lungs, liver, and left kidney, with the brain being markedly edematous. Both testes were descended and normal. Histologically, the retroperitoneal mass showed a malignant mixed germ cell tumor comprising choriocarcinoma, embryonal carcinoma, and teratoma components...
November 22, 2017: Journal of Forensic Sciences
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