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https://www.readbyqxmd.com/read/28817779/the-price-may-not-be-right-the-value-of-comparison-shopping-for-prescription-drugs
#1
Sanjay Arora, Neeraj Sood, Sophie Terp, Geoffrey Joyce
OBJECTIVES: To measure variations in drug prices across and within zip codes that may reveal simple strategies to improve patients' access to prescribed medications. STUDY DESIGN: We compared drug prices at different types of pharmacies across and within local markets. In-store prices were compared with a Web-based service providing discount coupons for prescription medications. Prices were collected for 2 generic antibiotics because most patients have limited experience with them and are less likely to know the price ranges for them...
July 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28817344/a-guide-to-approaching-regulatory-considerations-for-lentiviral-mediated-gene-therapies
#2
Michael White, Roger Whittaker, Carolina Gándara, Elizabeth A Stoll
Lentiviral vectors are increasingly the gene transfer tool of choice for gene or cell therapies, with multiple clinical investigations showing promise for this viral vector in terms of both safety and efficacy. The third-generation vector system is well characterized, effectively delivers genetic material and maintains long-term stable expression in target cells, delivers larger amounts of genetic material than other methods, is nonpathogenic, and does not cause an inflammatory response in the recipient. This report aims to help academic scientists and regulatory managers negotiate the governance framework to achieve successful translation of a lentiviral vector-based gene therapy...
August 2017: Human Gene Therapy Methods
https://www.readbyqxmd.com/read/28816094/theories-of-health-care-decision-making-at-the-end-of-life-a-meta-ethnography
#3
Kyounghae Kim, Katherine Heinze, Jiayun Xu, Melissa Kurtz, Hyunjeong Park, Megan Foradori, Marie T Nolan
The aim of this meta-ethnography is to appraise the types and uses of theories relative to end-of-life decision making and to develop a conceptual framework to describe end-of-life decision making among patients with advanced cancers, heart failure, and amyotrophic lateral sclerosis (ALS) and their caregivers or providers. We used PubMed, Embase, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases to extract English-language articles published between January 2002 and April 2015...
August 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28813993/the-influence-of-a-user-adaptive-prosthetic-knee-on-planned-gait-termination
#4
Erik C Prinsen, Marc J Nederhand, Bart F Koopman, Johan S Rietman
The added value of user-adaptive prosthetic knees has been predominantly evaluated in level walking or ramp/stair negotiation. Previous studies indicate that the activity pattern of individuals with an amputation mainly consists of short periods of continuous walking, indicating that a high percentage of ambulatory activity involves gait termination. The potential added value of user-adaptive prosthetic knees in gait termination has not been studied yet. Ten individuals with an amputation were measured with their own non-microprocessor controlled prosthetic knee and with the Rheo Knee II (a user-adaptive prosthetic knee)...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813992/review-of-the-actuators-of-active-knee-prostheses-and-their-target-design-outputs-for-activities-of-daily-living
#5
Dominik Simon Pieringer, Martin Grimmer, Michael Friedrich Russold, Robert Riener
Active prosthetic knees have the capability to provide net positive work, which is required in daily activities like stair and ramp negotiation or sit-to-stand transfers. Adding this capability might help to increase user mobility, safety, and independence. This article summarizes the biomechanical knee requirements for different activities of daily living and critically compares them with the actuator characteristics of state-of-the-art active prosthetic knee joints. As a result of a systematic literature research 22 active prosthetic knee joints were identified...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813292/re-thinking-dyadic-coping-in-the-context-of-chronic-illness
#6
REVIEW
Hoda Badr, Linda K Acitelli
In the past two decades scholars have increasingly recognized the importance of viewing chronic illness in a relationship context. However, questions remain regarding how couples make sense of illness, how they negotiate and coordinate coping, and the extent to which viewing the illness as a shared problem is beneficial for individual and relationship outcomes. This article seeks to clarify the role that couple relationships play in chronic illness adaptation by first describing major theoretical frameworks that have guided research in this area...
February 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813262/parenting-in-acculturation-two-contemporary-research-designs-and-what-they-tell-us
#7
REVIEW
Marc H Bornstein
Massive population transfers are common today. To understand how immigrants negotiate variation and adjustment as they settle in a new culture, researchers have explored acculturation, the changes that individuals and groups undergo as a result of contact with a culture not their own. Parents have crucial roles to play in acculturation. Parenting is instantiated in cognitions and practices, and cognitions and practices of parents are multifaceted and influenced by many factors, including parents' own individual characteristics, their children, and their cultural experiences...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28812844/clinician-perspectives-of-barriers-to-effective-implementation-of-a-rapid-response-system-in-an-academic-health-centre-a-focus-group-study
#8
John Rihari-Thomas, Michelle DiGiacomo, Jane Phillips, Phillip Newton, Patricia M Davidson
BACKGROUND: Systemic and structural issues of rapid response system (RRS) models can hinder implementation. This study sought to understand the ways in which acute care clinicians (physicians and nurses) experience and negotiate care for deteriorating patients within the RRS. METHODS: Physicians and nurses working within an Australian academic health centre within a jurisdictional-based model of clinical governance participated in focus group interviews. Verbatim transcripts were analysed using thematic content analysis...
January 1, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812809/trade-policy-and-health-adding-retrospective-studies-to-the-research-agenda-comment-on-the-trans-pacific-partnership-is-it-everything-we-feared-for-health
#9
Chantal Blouin
Prospective studies of the potential health consequences of trade and investment treaties, such as the Trans-Pacific Partnership, are critical. These studies can make visible to trade policy-makers the potential negative impacts associated to such treaties and can influence the outcomes of such negotiations. However, few researchers have examined retrospectively the consequences of trade agreements. With more than 400 trade agreements and more than 2000 investment treaties currently in force, researchers have a large corpus of agreements to analyse in order to assess not only their potential impacts on health system and population health, but also their actual impacts...
September 10, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812799/current-models-of-investor-state-dispute-settlement-are-bad-for-health-the-european-union-could-offer-an-alternative-comment-on-the-trans-pacific-partnership-is-it-everything-we-feared-for-health
#10
Martin McKee, David Stuckler
In this commentary, we endorse concerns about the health impact of the trans-pacific partnership (TPP), paying particular attention to its mechanisms for investor state dispute settlement. We then describe the different, judge-led approach being advocated by the European Commission team negotiating the Trans-Atlantic Trade and Investment Partnership, arguing that, while not perfect, it offers significant advantages.
August 20, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812449/balancing-performance-based-expectations-with-a-holistic-perspective-on-coaching-a-qualitative-study-of-swedish-women-s-national-football-team-coaches-practice-experiences
#11
Eva-Carin Lindgren, Natalie Barker-Ruchti
PURPOSE: The purpose of this study was to explore how an exclusive sample of women's national football team coaches described how they implement careful coaching while facing social and organizational pressure to win medals. METHOD: To consider coaches' negotiations, we drew on Noddings' concept of caring. Using an interpretive research paradigm, we conducted in-depth interviews with five Swedish women's national football team coaches. An abductive approach was used to simultaneously process the theoretical framework of "ethics of care" and the empirical data...
December 2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/28812229/economics-and-cost-effectiveness-of-multiple-sclerosis-therapies-in-the-usa
#12
REVIEW
Daniel M Hartung
Multiple sclerosis (MS) is a disabling, chronic disease that imposes a significant economic burden on patients and the US healthcare system. The largest cost component for individuals with MS are prescription drugs, specifically disease-modifying therapies (DMTs). Despite an increase in the number and diversity of DMTs over the past 10 years, acquisition costs for all DMTs have escalated dramatically at rates substantially higher than medical inflation. Currently, costs for most DMTs exceed $70,000 a year. Recent cost-effectiveness studies suggest the cost for nearly all DMTs exceeds generally accepted thresholds for what is considered a good value in the USA, even after factoring expected rebates...
August 15, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28810413/negotiations-between-health-and-social-goals-over-the-lifespan-the-role-of-future-time-perspective
#13
Kin-Kit Li
The interplay between health and social goals in relation to age and future time perspective was examined among 131 older and 131 younger adults via surveys and future time manipulations (limited, unchanged, and expansive). Being older was associated with weaker physical activity intentions and social activity intentions as mediated by a limited future time perspective. Physical activity intentions decreased in the limited condition and increased in the expansive condition, social activity intentions increased in all conditions, and preference toward health (over social) goals decreased in both the limited and expansive conditions...
February 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28810400/an-event-level-examination-of-successful-condom-negotiation-strategies-among-young-women
#14
Courtney Peasant, Erika A Montanaro, Trace S Kershaw, Gilbert R Parra, Nicole H Weiss, Jaimie P Meyer, James G Murphy, Tiarney D Ritchwood, Tami P Sullivan
This study examines the effect of condom negotiation strategies on condom use and partner type and substance use before sex as moderators of strategy effectiveness. Women reported their daily sexual behavior during the last month. Withholding sex was more strongly associated with condom use when utilized with a non-casual sex partner. Directly requesting condom use was more strongly and using deceptive reasons to influence condom use was less strongly related to condom use during substance use. Results underscore the importance of understanding the contexts in which condom negotiation strategies are successful in order to improve HIV/sexually transmitted infection prevention efforts among women...
January 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28807427/paediatric-fracture-clinic-re-design-incorporating-a-virtual-fracture-clinic
#15
Paul M Robinson, Francis Sim, Mark Latimer, Piers D Mitchell
INTRODUCTION: The use of virtual fracture clinics (VFCs) and home management protocols is increasing. The main aim of this research is to determine whether a paediatric home management programme and VFC can be used safely to manage a range of suitable fractures in children. MATERIALS AND METHODS: Protocols for the home management of stable paediatric fractures were designed by two consultant paediatric orthopaedic surgeons. These were for children between the ages of 18 months and 15 years 364 days...
August 4, 2017: Injury
https://www.readbyqxmd.com/read/28806946/improving-access-to-mental-health-care-in-an-orthodox-jewish-community-a-critical-reflection-upon-the-accommodation-of-otherness
#16
Phil McEvoy, Tracey Williamson, Raphael Kada, Debra Frazer, Chardworth Dhliwayo, Linda Gask
BACKGROUND: The English National Health Service (NHS) has significantly extended the supply of evidence based psychological interventions in primary care for people experiencing common mental health problems. Yet despite the extra resources, the accessibility of services for 'under-served' ethnic and religious minority groups, is considerably short of the levels of access that may be necessary to offset the health inequalities created by their different exposure to services, resulting in negative health outcomes...
August 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28805427/on-the-relative-importance-of-individual-level-characteristics-and-dyadic-interaction-effects-in-negotiations-variance-partitioning-evidence-from-a-twins-study
#17
Hillary Anger Elfenbein, Noah Eisenkraft, Jared R Curhan, Lisabeth F DiLalla
Negotiations are inherently dyadic. Negotiators' individual-level characteristics may not only make them perform better or worse in general, but also may make them particularly well- or poorly-suited to negotiate with a particular counterpart. The present research estimates the extent to which performance in a distributive negotiation is affected by (a) the negotiators' individual-level characteristics and (b) dyadic interaction effects that are defined by the unique pairings between the negotiators and their counterparts...
August 14, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28805424/the-dark-side-of-subjective-value-in-sequential-negotiations-the-mediating-role-of-pride-and-anger
#18
William J Becker, Jared R Curhan
Scholars who study negotiation increasingly recognize the importance of social context, seeing negotiations not merely as 1-shot interactions but as influenced by what came before. Under this longitudinal conceptualization of negotiation, a number of recent studies demonstrate that social psychological outcomes from prior negotiations are positively related to economic performance in subsequent negotiations when negotiating repeatedly with the same counterpart. In this report, we investigate a counterexample in the context of "sequential negotiations," which we define as multiple negotiation sessions that occur within a short time frame but facing different counterparts in each session...
August 14, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28804600/analysis-of-health-economics-assessment-reports-for-pharmaceuticals-in-france-understanding-the-underlying-philosophy-of-ceesp-assessment
#19
Mondher Toumi, Anastasiia Motrunich, Aurélie Millier, Cécile Rémuzat, Christos Chouaid, Bruno Falissard, Samuel Aballéa
Background: Despite the guidelines for Economic and Public Health Assessment Committee (CEESP) submission having been available for nearly six years, the dossiers submitted continue to deviate from them, potentially impacting product prices. Objective: to review the reports published by CEESP, analyse deviations from the guidelines, and discuss their implications for the pricing and reimbursement process. Study design: CEESP reports published until January 2017 were reviewed, and deviations from the guidelines were extracted...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28802979/navigating-professional-and-prescribing-boundaries-implementing-nurse-prescribing-in-new-zealand
#20
Anecita Gigi Lim, Nicola North, John Shaw
Non-medical prescribing is now well established in a number of countries. Because prescribing has traditionally been viewed as a medical role, there are inevitable interprofessional boundary tensions when non-medical prescribing is introduced. In New Zealand, enabling legislation has allowed nurse practitioners to apply for prescriptive authority after undertaking appropriate educational preparation. This study explored the experiences and perspectives of one of the first cohorts of nurse prescribers and their strategies in establishing the role and negotiating the associated professional boundaries...
August 8, 2017: Nurse Education in Practice
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