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https://www.readbyqxmd.com/read/28549584/suture-compression-induced-midpalatal-suture-chondrocyte-apoptosis-with-increased-caspase-3-caspase-9-bad-bak-bax-and-bid-expression
#1
Tingting Lan, Hanchi Zhao, Bilu Xiang, Jun Wang, Yang Liu
OBJECTIVE: Previous studies found bone resorption and chondrocytes loss in mouse models of mid-palatal suture when given continuous compressive force, although chondrocytes response remained unknown. Herein, we design this study to determine how continuous compression force induces chondrocytes apoptosis. METHODS: Thirty C57BL/6 male mice (aged 6 weeks) were randomly assigned into controls (not ligated to a spring), blank controls (ligated with no compression) and the compression group (ligated with 20-g compression)...
May 23, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28548706/45-gy-is-not-sufficient-radiotherapy-dose-for-group-iii-orbital-embryonal-rhabdomyosarcoma-after-less-than-complete-response-to-12-weeks-of-arst0331-chemotherapy-a-report-from-the-soft-tissue-sarcoma-committee-of-the-children-s-oncology-group
#2
Ralph P Ermoian, John Breneman, David O Walterhouse, Yueh-Yun Chi, Jane Meza, James Anderson, Douglas S Hawkins, Andrea A Hayes-Jordan, David M Parham, Torunn I Yock, Sarah S Donaldson, Suzanne L Wolden
BACKGROUND: Recent Children's Oncology Group (COG) trials tested the efficacy of reduced therapy in an effort to lessen late effects compared to the Intergroup Rhabdomyosarcoma Study (IRS) IV regimen with associated hematologic and hepatic toxicity, and infertility. Here, we analyze the efficacy of 45 Gray (Gy) local radiotherapy (RT) in patients with Group III orbital embryonal rhabdomyosarcoma (ERMS) enrolled on the COG low-risk study ARST0331. PROCEDURE: Sixty-two patients with Group III orbital ERMS were treated on ARST0331 with four cycles of vincristine (VCR), dactinomycin (DACT), and cyclophosphamide (CPM; VAC, total cumulative CPM dose 4...
May 26, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28548643/condensed-versus-standard-schedule-of-high-dose-cytarabine-consolidation-therapy-with-pegfilgrastim-growth-factor-support-in-acute-myeloid-leukemia
#3
S Jaramillo, A Benner, J Krauter, H Martin, T Kindler, M Bentz, H R Salih, G Held, C-H Köhne, K Götze, M Lübbert, A Kündgen, P Brossart, M Wattad, H Salwender, B Hertenstein, D Nachbaur, G Wulf, H-A Horst, H Kirchen, W Fiedler, A Raghavachar, G Russ, S Kremers, E Koller, V Runde, G Heil, D Weber, G Göhring, K Döhner, A Ganser, H Döhner, R F Schlenk
The aim of this cohort study was to compare a condensed schedule of consolidation therapy with high-dose cytarabine on days 1, 2 and 3 (HDAC-123) with the HDAC schedule given on days 1, 3 and 5 (HDAC-135) as well as to evaluate the prophylactic use of pegfilgrastim after chemotherapy in younger patients with acute myeloid leukemia in first complete remission. One hundred and seventy-six patients were treated with HDAC-135 and 392 patients with HDAC-123 with prophylactic pegfilgrastim at days 10 and 8, respectively, in the AMLSG 07-04 and the German AML Intergroup protocol...
May 26, 2017: Blood Cancer Journal
https://www.readbyqxmd.com/read/28548471/recurrent-mitral-paravalvular-leak-benefits-of-leak-site-repair-compared-to-re-replacement
#4
Jae-Woong Choi, Ho Y Hwang, Kyung H Kim, Ki-Bong Kim, Hyuk Ahn
BACKGROUND: Mitral paravalvular leak (PVL) recurrence after surgical correction has not yet been well demonstrated. The aims of this study were (1) to evaluate the long-term results of surgical mitral PVL correction, including recurrent PVL, and (2) to elucidate the factors including surgical technique that affect the risk of recurrent PVL. METHODS: Eighty-six patients who underwent surgical treatment for mitral PVL were enrolled in this study. Thirty-six patients underwent leak site repair (MVP group), and 50 patients underwent re-replacement (MVR group)...
May 26, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28547845/institutional-apologies-and-socio-emotional-climate-in-the-south-american-context
#5
Magdalena Bobowik, Darío Páez, Maitane Arnoso, Manuel Cárdenas, Bernard Rimé, Elena Zubieta, Marcela Muratori
This study examined perceptions of institutional apologies related to past political violence and socio-emotional climate among victims and non-victims in Argentina (n = 518), Chile (n = 1,278), and Paraguay (n = 1,172) based on quasi-representative samples. The perceptions of apology as sincere and efficient in improving intergroup relations were associated with a positive socio-emotional climate across the three nations. Victims evaluated apologies more positively and perceived a more positive socio-emotional climate compared to non-victims in Paraguay and Argentina, whereas the opposite was true in Chile where the government opposed the victims' leftist political orientation...
May 25, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28547824/the-promise-of-a-better-group-future-cognitive-alternatives-increase-students-self-efficacy-and-academic-performance
#6
Aarti Iyer, Airong Zhang, Jolanda Jetten, Zhen Hao, Lijuan Cui
Drawing on classic social identity theorizing (Tajfel, Differentiation between social groups: Studies in the social psychology of intergroup relations, London, UK, Academic Press, 1978), we propose that low-status minority group members' self-efficacy and performance on intellectual tasks can be enhanced by prompting them to believe in a better future for their group (i.e., increasing awareness of cognitive alternatives to the existing low-status position). Study 1 manipulated cognitive alternatives among 157 migrant workers' children in China, showing that self-efficacy was enhanced in the high compared to the low cognitive alternative condition...
May 25, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28546783/culture-meets-collective-action-exciting-synergies-and-some-lessons-to-learn-for-the-future
#7
Martijn van Zomeren, Winnifred R Louis
In this introduction to the special issue of Group Processes & Intergroup Relations on "Culture and Collective Action" we emphasize the importance of the special issue topic for the development of the field. Specifically, we highlight the globalization of collective action and the internationalization of the social-psychological study of collective action, both of which point to culture as a missing link for this field. We thus propose that the next step is to move toward a proper cultural psychology of collective action-a social psychology in which culture is an integral part...
May 2017: Group Processes & Intergroup Relations: GPIR
https://www.readbyqxmd.com/read/28545173/comparison-of-short-term-complications-of-general-and-spinal-anesthesia-for-primary-unilateral-total-knee-arthroplasty
#8
Yong Bok Park, Won Seok Chae, Sin Hyung Park, Ji Soo Yu, Sun Geun Lee, Soo Jae Yim
Purpose: To compare the occurrences of perioperative complications of two anesthetic techniques (general anesthesia [GA] and spinal anesthesia [SA] in patients undergoing primary unilateral total knee arthroplasty (TKA). Materials and Methods: Patients who underwent unilateral primary TKA due to osteoarthritis from January 2005 to January 2014 were retrospectively reviewed. They were divided into two groups: GA (n=490) and SA (n=746). The operation duration, length of perioperative stay in the operation room and occurrences of adverse events in postoperative 30 days (mean, 29...
June 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28542910/personal-control-decreases-narcissistic-but-increases-non-narcissistic-in-group-positivity
#9
Aleksandra Cichocka, Agnieszka Golec de Zavala, Marta Marchlewska, Michał Bilewicz, Manana Jaworska, Mateusz Olechowski
OBJECTIVE: We examined the effects of control motivation on in-group positivity. Past research suggests that people compensate for low personal control by increasing support for social in-groups. We predicted that the effect of personal control on in-group positivity would depend on the type of in-group positivity. Low personal control should increase compensatory, narcissistic in-group positivity, while high personal control should increase secure, non-narcissistic in-group positivity...
May 22, 2017: Journal of Personality
https://www.readbyqxmd.com/read/28541641/update-on-rare-epithelial-ovarian-cancers-based-on-the-rare-ovarian-tumors-young-investigator-conference
#10
REVIEW
Ji Yon Agnes Jang, Nozomu Yanaihara, Eric Pujade-Lauraine, Yoshiki Mikami, Katsutoshi Oda, Michael Bookman, Jonathan Ledermann, Muneaki Shimada, Takako Kiyokawa, Byoung Gie Kim, Noriomi Matsumura, Tsunehisa Kaku, Takafumi Kuroda, Yoko Nagayoshi, Ayako Kawabata, Yasushi Iida, Jae Weon Kim, Michael Quinn, Aikou Okamoto
There has been significant progress in the understanding of the pathology and molecular biology of rare ovarian cancers, which has helped both diagnosis and treatment. This paper provides an update on recent advances in the knowledge and treatment of rare ovarian cancers and identifies gaps that need to be addressed by further clinical research. The topics covered include: low-grade serous, mucinous, and clear cell carcinomas of the ovary. Given the molecular heterogeneity and the histopathological rarity of these ovarian cancers, the importance of designing adequately powered trials or finding statistically innovative ways to approach the treatment of these rare tumors has been emphasized...
July 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28538296/exercise-intensity-and-technical-demands-of-small-sided-soccer-games-for-under-12-and-under-14-players-effect-of-area-per-player
#11
Domenico Martone, Moreno Giacobbe, Adriano Capobianco, Esther Imperlini, Annamaria Mancini, Mario Capasso, Pasqualina Buono, Stefania Orrù
Martone, D, Giacobbe, M, Capobianco, A, Imperlini, E, Mancini, A, Capasso, M, Buono, P, and Orrù, S. Exercise intensity and technical demands of small-sided soccer games for under-12 and under-14 players: Effect of area per player. J Strength Cond Res 31(6): 1486-1492, 2017-The aim of this study was to evaluate the effects of 6 different areas per player (AP) on exercise intensity (EI) measured during small-sided games (SSGs) and expressed as percentage of maximal heart rate (%MHR) and technical actions (TAs) involvement with the ball, crosses, headers, tackles, shots on goal, dribbling, passing, and target passing-in U-12 and U-14 soccer players during SSGs...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28536308/immune-correlates-of-gm-csf-and-melanoma-peptide-vaccination-in-a-randomized-trial-for-the-adjuvant-therapy-of-resected-high-risk-melanoma-e4697
#12
Lisa H Butterfield, Fengmin Zhao, Sandra Lee, Ahmad A Tarhini, Kim A Margolin, Richard L White, Michael Atkins, Gary I Cohen, Theresa L Whiteside, John M Kirkwood, David H Lawson
Purpose: E4697 was a multi-center intergroup randomized placebo-controlled Phase III trial of adjuvant GM-CSF and/or a multi-epitope melanoma peptide vaccine for patients with completely resected, high-risk stage III/IV melanoma. <p>Experimental Design: 815 patients were enrolled from 12/99 to 10/06 into this 6-arm study. GM-CSF was chosen to promote the numbers and functions of dendritic cells (DC). The melanoma antigen peptide vaccine (Tyrosinase368-376 (370D), gp100209-217 (210M), MART-127-35) in Montanide was designed to promote melanoma specific CD8(+) T cell responses...
May 23, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28535890/impacts-of-social-support-on-symptoms-in-brazilian-women-with-fibromyalgia
#13
Rodrigo Pegado de Abreu Freitas, Sandra Cristina de Andrade, Maria Helena Constantino Spyrides, Maria Thereza Albuquerque Barbosa Cabral Micussi, Maria Bernardete Cordeiro de Sousa
We aimed to assess the impact of social support on symptoms in Brazilian women with FM. An observational, descriptive study enrolling 66 women who met the 1990 American College of Rheumatology (ACR) criteria. Social support was measured by the Social Support Survey (MOS-SSS), functionality was evaluated using the Fibromyalgia Impact Questionnaire (FIQ), depression was assessed using the Beck Depression Inventory (BDI), anxiety was measured using the Hamilton Anxiety Scale (HAS), affectivity was measured by Positive and Negative Affect Schedule (PANAS), and algometry was carried out to record pressure pain threshold (PPth) and tolerance (PPTo) at 18 points recommended by the ACR...
May 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28533598/effect-of-bilateral-upper-extremity-exercise-on-trunk-performance-in-patients-with-stroke
#14
Doo Ho Lee, Seong Hoon Park, Ji Won Han
[Purpose] The aim of this study was to investigate the effect of bilateral upper extremity exercises on trunk performance in patients with stroke. [Subjects and Methods] Twenty in-patients with chronic stroke of at least 6 month's duration participated in this study. Patients in the experimental and control groups received neurological rehabilitation treatment for stroke. In addition to the neurological rehabilitation treatment, patients in the experimental group received 30 minutes of bilateral upper extremity exercises 3 times weekly for 4 weeks...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28523257/comparative-evaluation-of-salivary-neopterin-levels-and-its-effects-to-periodontal-therapy-in-pre-and-post-menopausal-women
#15
Jammula Surya Prasanna, Chinta Sumadhura, Parupalli Karunakar, Naineni Rohini
OBJECTIVES: Neopterin is a valuable diagnostic biomarker, which is elevated in inflammatory conditions like periodontitis, that is characterized by destruction of the supporting structures of the teeth. Among the biomarkers, neopterin occurs in body fluids, and acts as a diagnostic marker for present and future disease activity. METHODS: Thirty female subjects with chronic periodontitis, mean age 50 years (40-60 years) were included in this study. Depending upon their menstrual history, subjects were categorized into two groups of fifteen each...
April 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28523245/impact-of-skeletal-divergence-on-oral-health-related-quality-of-life-and-self-reported-jaw-function
#16
Joseph Safwat Antoun, William Murray Thomson, Tony Raymond Merriman, Roberto Rongo, Mauro Farella
OBJECTIVE: To investigate the differences in oral health-related quality of life (OHRQoL) and self-reported jaw function between patients with hyperdivergent and normodivergent facial types. METHODS: Eighty patients with a distinctively hyperdivergent facial type (mandibular plane angle greater than 2 standard deviations, or 42°) and 80 controls were individually matched according to age, sex, ethnicity, and treatment stage. Data were collected using self-report questionnaires such as the Oral Health Impact Profile (OHIP-14) and Jaw Functional Limitation Scale (JFLS-8)...
May 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28523243/maxillomandibular-arch-width-differences-at-estimated-centers-of-resistance-comparison-between-normal-occlusion-and-skeletal-class-iii-malocclusion
#17
Yun-Jin Koo, Sung-Hwan Choi, Byeong-Tak Keum, Hyung-Seog Yu, Chung-Ju Hwang, Birte Melsen, Kee-Joon Lee
OBJECTIVE: To evaluate the differences in maxillomandibular transverse measurements at either the crown or the estimated center of resistance (CR), and to compare values between normal occlusion and Class III malocclusion groups. METHODS: Dental casts and computed tomography (CT) data from 30 individuals with normal occlusion and 30 with skeletal Class III malocclusions were evaluated. Using the casts, dental arch widths (DAWs) were measured from the cusp tips, and basal arch widths (BAWs-cast) were measured as the distance between the points at the mucogingival junction adjacent to the respective cusp tips...
May 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28520827/surgical-outcomes-of-bony-batten-grafting-to-correct-caudal-septal-deviation-in-septoplasty
#18
Do-Youn Kim, Sung Hoon Nam, Sami E Alharethy, Yong Ju Jang
Improtance: Correction of caudal septal deviation with a batten graft has been popularized recently. However, few reports have documented the surgical outcomes of this technique, especially the use of bony batten grafts in septoplasty. Objective: To evaluate the surgical outcomes of bony batten grafting for the management of caudal septal deviation in endonasal septoplasty. Design, Setting, and Participants: This retrospective cohort study evaluates the medical records of 141 patients with caudal septal deviation who underwent septoplasty using bony batten grafts from September 1, 2011, through February 29, 2016, at a tertiary referral hospital...
May 18, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28516338/intergroup-variation-in-robbing-and-bartering-by-long-tailed-macaques-at-uluwatu-temple-bali-indonesia
#19
Fany Brotcorne, Gwennan Giraud, Noëlle Gunst, Agustín Fuentes, I Nengah Wandia, Roseline C Beudels-Jamar, Pascal Poncin, Marie-Claude Huynen, Jean-Baptiste Leca
Robbing and bartering (RB) is a behavioral practice anecdotally reported in free-ranging commensal macaques. It usually occurs in two steps: after taking inedible objects (e.g., glasses) from humans, the macaques appear to use them as tokens, returning them to humans in exchange for food. While extensively studied in captivity, our research is the first to investigate the object/food exchange between humans and primates in a natural setting. During a 4-month study in 2010, we used both focal and event sampling to record 201 RB events in a population of long-tailed macaques (Macaca fascicularis), including four neighboring groups ranging freely around Uluwatu Temple, Bali (Indonesia)...
May 17, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28510354/that-s-what-friends-are-for-how-intergroup-friendships-promote-historically-disadvantaged-groups-substantive-political-representation
#20
Andrej Kokkonen, David Karlsson
The interests of historically disadvantaged groups risk being overlooked if they are not present in the decision-making process. However, a mere presence in politics does not guarantee political success. Often groups need allies to promote their interests successfully. We argue that one way to identify such allies is to judge politicians by whether they have friends in historically disadvantaged groups, as intergroup friendships have been shown to make people understand and feel empathy for outgroups. In other words, intergroup friendships may function as an important complement to descriptive representation...
May 16, 2017: British Journal of Sociology
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