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https://www.readbyqxmd.com/read/28345066/correlation-of-central-venous-pressure-with-venous-blood-gas-analysis-parameters-a-diagnostic-study
#1
Sima Rahim-Taleghani, Alireza Fatemi, Mostafa Alavi Moghaddam, Majid Shojaee, Abdelrahman Ibrahim Abushouk, Mohammad Mehdi Forouzanfar, Alireza Baratloo
OBJECTIVE: This study was conducted to assess the correlation between central venous pressure (CVP) and venous blood gas (VBG) analysis parameters, to facilitate management of severe sepsis and septic shock in emergency department. MATERIAL AND METHODS: This diagnostic study was conducted from January 2014 until June 2015 in three major educational medical centers, Tehran, Iran. For patients selected with diagnosis of septic shock, peripheral blood sample was taken for testing the VBG parameters and the anion gap (AG) was calculated...
March 2017: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28340057/long-term-outcome-of-pulmonary-vein-isolation-in-patients-with-paroxysmal-atrial-fibrillation-and-brugada-syndrome
#2
Giacomo Mugnai, Burak Hünük, Erwin Ströker, Diego Ruggiero, Hugo Enrique Coutino-Moreno, Ken Takarada, Valentina De Regibus, Rajin Choudhury, Juan Pablo Abugattas de Torres, Darragh Moran, Saverio Iacopino, Pasquale Filannino, Giulio Conte, Juan Sieira, Jan Poelaert, Stefan Beckers, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia
Aims: The therapeutical management of atrial fibrillation (AF) in the setting of Brugada syndrome (BS) might be challenging as many antiarrhythmic drugs (AADs) with sodium channel blocking properties might lead to to the development of ventricular arrhythmias. This study sought to evaluate the clinical outcome in a consecutive series of patients with BS having undergone pulmonary vein (PV) isolation by means of radiofrequency (RF) or cryoballoon (CB) ablation and the efficacy of catheter ablation for preventing inappropriate interventions delivered by implantable cardioverter defibrillators (ICD) on a 3-year follow up...
March 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28338592/open-abdomen-with-vacuum-assisted-wound-closure-and-mesh-mediated-fascial-traction-in-patients-with-complicated-diffuse-secondary-peritonitis-a-single-center-8-year-experience
#3
Matti Tolonen, Panu Mentula, Ville Sallinen, Suvi Rasilainen, Minna Bäcklund, Ari Leppäniemi
BACKGROUND: Open abdomen (OA) treatment in patients with peritonitis is increasing worldwide. Various temporary abdominal closure devices are being used. This study included patients with complicated diffuse secondary peritonitis, OA, and vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM). The aim of this study was to describe mortality and major morbidity in terms of delayed primary fascial closure (DPFC) and enteroatmospheric fistula rates. METHODS: This was a single academic center retrospective study of consecutive patients with diffuse peritonitis, OA, and VAWCM between years 2008-2016...
March 23, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28337487/gender-discrimination-gender-disparities-in-obesity-and-human-development
#4
Fabrizio Ferretti, Michele Mariani
Measuring gender inequality and women's empowerment is essential to understand the determinants of gender gaps, evaluate policies and monitor countries' progress. With this aim, over the past two decades, research has mainly been directed towards the development of composite indices. The purpose of this paper is to introduce a new and interdisciplinary perspective to the current debate on measuring gender inequality in human development. As a starting point, we develop a simple macroeconomic model of the interdependence between human development and gender inequality...
March 2017: Heliyon
https://www.readbyqxmd.com/read/28333037/cerebral-hemodynamic-with-intra-aortic-balloon-pump-business-as-usual
#5
Juliana Caldas, Ronney B Panerai, Edson Bor-Seng-Shu, Juliano Almeida, Graziela Ferreira, Ligia Cunha, Ricardo Nogueira, Marcelo Oliveira, Fabio Jatene, Thompson Robinson, Ludhmila Hajjar
Intra-aortic balloon pump (IABP) is commonly used as mechanical support after cardiac surgery or cardiac shock. Although its benefits for cardiac function have been well documented, its effects on cerebral circulation are still controversial. We hypothesized that transfer function analysis (TFA) and continuous estimates of dynamic cerebral autoregulation (CA) provide consistent results in the assessment of cerebral autoregulation in patients with IABP. Continuous recordings of blood pressure (BP, intra-arterial line), end-tidal CO2, heart rate and cerebral blood flow velocity (CBFV, transcranial Doppler) were obtained i) 5 minutes with IABP ratio 1:3, ii) 5 minutes, starting 1 minute with the IABP-ON, and continuing for another 4 minutes without pump assistance (IABP-OFF)...
March 23, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28328682/early-tranexamic-acid-administration-ameliorates-the-endotheliopathy-of-trauma-and-shock-in-an-in-vitro-model
#6
Lawrence N Diebel, Jonathan V Martin, David M Liberati
BACKGROUND: Systemic vascular endothelial injury is a consequence of trauma-hemorrhagic shock (T/HS) which results in disturbances of coagulation, inflammation and endothelial barrier integrity. The effect of T/HS on the endothelium (Endotheliopathy of Trauma)[EoT] is of intense research interest and may lead to EoT directed therapies. Administration of tranexamic acid (TXA) in trauma patients is associated with a survival benefit and fewer complications if given early after injury. Mechanisms for this protective effect include the anti-fibrinolytic and anti-inflammatory effects of TXA...
March 21, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28321801/acute-hyperventilation-increases-the-central-venous-to-arterial-pco2-difference-in-stable-septic-shock-patients
#7
Jihad Mallat, Usman Mohammad, Malcolm Lemyze, Mehdi Meddour, Marie Jonard, Florent Pepy, Gaelle Gasan, Stephanie Barrailler, Johanna Temime, Nicolas Vangrunderbeeck, Laurent Tronchon, Didier Thevenin
BACKGROUND: To evaluate the effects of acute hyperventilation on the central venous-to-arterial carbon dioxide tension difference (∆PCO2) in hemodynamically stable septic shock patients. METHODS: Eighteen mechanically ventilated septic shock patients were prospectively included in the study. We measured cardiac index (CI), ∆PCO2, oxygen consumption (VO2), central venous oxygen saturation (ScvO2), and blood gas parameters, before and 30 min after an increase in alveolar ventilation (increased respiratory rate by 10 breaths/min)...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28303647/ratio-of-systolic-blood-pressure-to-left-ventricular-end-diastolic-pressure-at-the-time-of-primary-percutaneous-coronary-intervention-predicts-in-hospital-mortality-in-patients-with-st-elevation-myocardial-infarction
#8
Michael Sola, Kiran Venkatesh, Melissa Caughey, Robert Rayson, Xuming Dai, George A Stouffer, Michael Yeung
OBJECTIVE: To determine the ability of simple hemodynamic parameters obtained at the time of cardiac catheterization to predict in-hospital mortality following ST-elevation myocardial infarction (STEMI). BACKGROUND: Hemodynamic parameters measured at the time of primary percutaneous coronary intervention (PPCI) could potentially identify high-risk patients who would benefit from aggressive hemodynamic support in the Cardiac Catheterization laboratory. METHODS: This is a retrospective single-center study of 219 consecutive patients with STEMI...
March 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28291451/prehospital-blood-transfusion-during-aeromedical-evacuation-of-trauma-patients-in-israel-the-idf-csar-experience
#9
Jacob Chen, Avi Benov, Roy Nadler, Daniel N Darlington, Andrew P Cap, Ari M Lipsky, Elon Glassberg
BACKGROUND: Data regarding the effect of prehospital blood administration to trauma patients during short-to-moderate time evacuations is scarce. The Israel Air Force Airborne Combat Search and Rescue is the only organization that deals with aeromedical evacuation for both military and civilian casualties in Israel and the only one with the ability to give blood in the prehospital setting. METHODS: Data on packed red blood cells (PRBCs) administration in the evacuation missions from January 2003 to June 2010 were analyzed and actual transfusion practice was compared to clinical practice guidelines (CPGs)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289531/critical-analysis-of-ineffective-post-implantation-implantable-cardioverter-defibrillator-testing
#10
Markus Roos, J Christoph Geller, Marc-Alexander Ohlow
AIM: To test of the implantable-cardioverter-defibrillator is done at the time of implantation. We investigate if any testing should be performed. METHODS: All consecutive patients between January 2006 and December 2008 undergoing implantable cardioverter-defibrillator (ICD) implantation/replacement (a total of 634 patients) were included in the retrospective study. RESULTS: Sixteen patients (2.5%) were not tested (9 with LA/LV-thrombus, 7 due to operator's decision)...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28286265/vicarious-extinction-learning-during-reconsolidation-neutralizes-fear-memory
#11
Armita Golkar, Cathelijn Tjaden, Merel Kindt
BACKGROUND: Previous studies have suggested that fear memories can be updated when recalled, a process referred to as reconsolidation. Given the beneficial effects of model-based safety learning (i.e. vicarious extinction) in preventing the recovery of short-term fear memory, we examined whether consolidated long-term fear memories could be updated with safety learning accomplished through vicarious extinction learning initiated within the reconsolidation time-window. We assessed this in a final sample of 19 participants that underwent a three-day within-subject fear-conditioning design, using fear-potentiated startle as our primary index of fear learning...
February 22, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28282883/the-shock-pulse-index-and-its-application-in-the-fault-diagnosis-of-rolling-element-bearings
#12
Peng Sun, Yuhe Liao, Jin Lin
The properties of the time domain parameters of vibration signals have been extensively studied for the fault diagnosis of rolling element bearings (REBs). Parameters like kurtosis and Envelope Harmonic-to-Noise Ratio are the most widely applied in this field and some important progress has been made. However, since only one-sided information is contained in these parameters, problems still exist in practice when the signals collected are of complicated structure and/or contaminated by strong background noises...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28280039/pathway-specific-aggregate-biomarker-risk-score-is-associated-with-burden-of-coronary-artery-disease-and-predicts-near-term-risk-of-myocardial-infarction-and-death
#13
Nima Ghasemzedah, Salim S Hayek, Yi-An Ko, Danny J Eapen, Riyaz S Patel, Pankaj Manocha, Hatem Al Kassem, Mohamed Khayata, Emir Veledar, Dimitrios Kremastinos, Christian W Thorball, Tomasz Pielak, Sergey Sikora, A Maziar Zafari, Stamatios Lerakis, Laurence Sperling, Viola Vaccarino, Stephen E Epstein, Arshed A Quyyumi
BACKGROUND: Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events. A biomarker risk score (BRS) based on the circulating levels of biomarkers C-reactive protein, fibrin degradation products, and heat shock protein-70 representing these 3 pathways was a strong predictor of future outcomes. We investigated whether soluble urokinase plasminogen activator receptor (suPAR), a marker of immune activation, is predictive of outcomes independent of the aforementioned markers and whether its addition to a 3-BRS improves risk reclassification...
March 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28276957/evaluation-of-the-relationship-between-salivary-concentration-of-anti-heat-shock-protein-immunoglobulin-and-clinical-manifestations-of-beh%C3%A3-et-s-disease
#14
M Doino, M Yokoyama, Y Sasaki, K Kondo, Y Yasuda, S Arakawa
OBJECTIVE: This study investigated the relationship between the concentration of anti-heat shock protein (HSP) 60 antibody in resting saliva and the severity of Behçet's disease (BD). METHOD: Sixty-five patients diagnosed with BD at Tokyo Medical and Dental University Hospital were enrolled in this study. Based on clinical severity scores, patients were categorized as having mild, moderate, or severe BD. Periodontal status was evaluated with the Community Periodontal Index (CPI), and anti-HSP60 antibody concentrations in resting saliva were measured with an enzyme-linked immunosorbent assay...
February 14, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28276709/high-fat-diet-effects-on-metabolic-responses-to-chronic-stress
#15
Marzieh Nemati, Homeira Zardooz, Fatemeh Rostamkhani, Alireza Abadi, Forough Foroughi
CONTEXT: High-fat diets and chronic stress are prevalent risk factors for various chronic diseases in modern societies. OBJECTIVE: This study investigated the effect of high-fat diet on glucose-related metabolic responses to chronic foot-shock stress. MATERIALS AND METHODS: Male rats were divided into high-fat diet (containing 54.21% saturated and 44.89% unsaturated fatty acids) and normal diet groups and then into stress and non-stress subgroups...
March 3, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28268811/occurrence-of-elevated-shock-index-in-acute-patients-and-development-of-a-proportional-shock-index-metric
#16
Thomas Schmidt, Annmarie Lassen, Uffe Kock Wiil
Although shock index, as the ratio between heart rate and systolic blood pressure, is a well-recognized predictor for adverse outcomes, it is seldom integrated into clinical evaluation procedures as it requires on-the-fly evaluation of multiple terms. In this paper, we investigate the prevalence of elevated shock index in emergency department patients through an analysis of automatic heart rate and blood pressure readings from 809 admissions to an acute bedside ward at a large Danish hospital. The analysis is conducted by evaluating differences in terms of 30 day mortality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28254686/impact-of-inadequate-initial-antimicrobial-therapy-on-mortality-in-patients-with-bacteraemic-cholangitis-a-retrospective-cohort-study
#17
Yasuaki Tagashira, Naoya Sakamoto, Toshiaki Isogai, Mayu Hikone, Atsushi Kosaka, Ran Chino, Masanori Higuchi, Yuki Uehara, Hitoshi Honda
OBJECTIVES: Acute cholangitis is a common cause of bacteraemia resulting in severe sepsis or septic shock. The impact of the appropriate initial antimicrobial therapy on short-term mortality in bacteraemic cholangitis has not been well investigated. METHODS: We conducted a retrospective cohort study of patients with bacteraemic cholangitis at two large tertiary care centres in Tokyo, Japan between 2009 and 2015. We determined the factors associated with 30-day all-cause mortality from the date of drawing the first positive blood culture, using a multivariate logistic regression analysis...
February 27, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28252537/daily-lowest-hemoglobin-and-risk-of-organ-dysfunctions-in-critically-ill-patients
#18
Sarah J Hemauer, Adam J Kingeter, Xue Han, Matthew S Shotwell, Pratik P Pandharipande, Liza M Weavind
OBJECTIVES: To determine the association between hemoglobin levels and the daily risk of individual organ dysfunctions in critically ill patients. DESIGN: Post hoc analysis of prospectively collected data. SETTING: Vanderbilt University Medical Center and Saint Thomas Hospital Medical and Surgical ICUs. PATIENTS: Medical and surgical ICU patients admitted with respiratory failure or shock. INTERVENTIONS: Baseline demographic data, and detailed in-ICU and hospital data, including daily lowest hemoglobin, were collected up to hospital day 30...
March 1, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28251488/acute-exercise-boosts-cell-proliferation-and-the-heat-shock-response-in-lymphocytes-correlation-with-cytokine-production-and-extracellular-to-intracellular-hsp70-ratio
#19
Thiago Gomes Heck, Sofia Pizzato Scomazzon, Patrícia Renck Nunes, Cinthia Maria Schöler, Gustavo Stumpf da Silva, Aline Bittencourt, Maria Cristina Faccioni-Heuser, Mauricio Krause, Roberto Barbosa Bazotte, Rui Curi, Paulo Ivo Homem de Bittencourt
Exercise stimulates immune responses, but the appropriate "doses" for such achievements are unsettled. Conversely, in metabolic tissues, exercise improves the heat shock (HS) response, a universal cytoprotective response to proteostasis challenges that are centred on the expression of the 70-kDa family of intracellular heat shock proteins (iHSP70), which are anti-inflammatory. Concurrently, exercise triggers the export of HSP70 towards the extracellular milieu (eHSP70), where they work as pro-inflammatory cytokines...
March 1, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/28248014/-clinical-implications-of-shear-wave-ultrasound-elastography-for-evaluation-of-urinary-stones
#20
I G Kraev, V I Rudenko, A V Amosov, G E Krupinov, T M Ganzha
INTRODUCTION: Currently, extracorporeal shock wave lithotripsy (ESWL) is a minimally invasive treatment for patients with urolithiasis. With advancing medical technology, elastography has evolved as a method for measuring the elasticity of tissues. AIM: To investigate the elasticity of urinary stones for assessing their physical and chemical composition. MATERIALS AND METHODS: The elasticity of urinary stones was determined before ESWL in 30 urolithiasis patients (18 men and 12 women, aged 25-65 years) using shear wave ultrasound elastography (SWUE)...
November 2016: Urologii︠a︡
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