L Quack, S Glatter, A Wegener-Panzer, R Cleaveland, A Bertolini, V Endmayr, R Seidl, M Breu, E Wendel, M Schimmel, M Baumann, M Rauchenzauner, M Pritsch, N Boy, T Muralter, G Kluger, C Makoswski, V Kraus, S Leiz, C Loehr-Nilles, J H Kreth, S Braig, S Schilling, J Kern, C Blank, B Tro Baumann, S Vieth, M Wallot, M Reindl, H Ringl, K P Wandinger, F Leypoldt, R Höftberger, K Rostásy
BACKGROUND: Acute cerebellitis (AC) in children and adolescents is an inflammatory disease of the cerebellum due to viral or bacterial infections but also autoimmune-mediated processes. OBJECTIVE: To investigate the frequency of autoantibodies in serum and CSF as well as the neuroradiological features in children with AC. MATERIAL AND METHODS: Children presenting with symptoms suggestive of AC defined as acute/subacute onset of cerebellar symptoms and MRI evidence of cerebellar inflammation or additional CSF pleocytosis, positive oligoclonal bands (OCBs), and/or presence of autoantibodies in case of negative cerebellar MRI...
November 2023: European Journal of Paediatric Neurology: EJPN