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Hypertension atherosclerosis

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https://www.readbyqxmd.com/read/28107730/systemic-atherosclerosis-and-voiding-symptom
#1
A Ozgur Yeniel, A Mete Ergenoglu, Reci Meseri, Anıl Ari, Ceren Sancar, Ismail Mete Itil
OBJECTIVE: To evaluate the effect of atherosclerosis on the storage and voiding symptoms of the bladder in women with overactive bladder (OAB). STUDY DESIGN: We retrospectively reviewed the charts of women with OAB who were evaluated between 2013 and 2015 in our urogynecology unit. Charts were assessed for history, examination findings, urinary diary, quality of life (QOL) questionnaires, urodynamic studies (UDSs), and four main risk factors for atherosclerosis: hypertension, diabetes mellitus, smoking, and hyperlipidemia...
January 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28103361/the-relationship-between-body-composition-and-renal-resistive-index-in-new-diagnosed-hypertensive-patients
#2
S Karakan, B Inan, A Aktas, H Yavuz
Objective: Obesity is a major modifiable risk factor for atherosclerosis. Thus, early risk markers are needed to identify obese subjects. The objective of this study was to examine the relationship between body composition and arterial stiffness documented by Doppler-derived renal resistive index (RRI). Materials/Subjects and Methods: We enrolled 120 new-diagnosed hypertensive patients (mean age 45±8 years) who were admitted to our nephrology clinic. Body fat percentage (BFP) was measured by bioelectrical impedance (BIA)...
February 18, 2016: West Indian Medical Journal
https://www.readbyqxmd.com/read/28103312/increased-cardiovascular-events-and-subclinical-atherosclerosis-in-rheumatoid-arthritis-patients-1-year-prospective-single-centre-study
#3
Piero Ruscitti, Paola Cipriani, Francesco Masedu, Silvio Romano, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Di Benedetto, Saverio Alvaro, Maria Penco, Marco Valenti, Roberto Giacomelli
OBJECTIVES: Several studies showed the close relationship between Rheumatoid Arthritis (RA) and cerebro-cardiovascular events (CVEs) and subclinical atherosclerosis. In this study, we investigated the occurrence of CVEs and subclinical atherosclerosis during the course of RA and we evaluated the possible role of both traditional cardiovascular (CV) and disease related risk factors to predict the occurrence of new CVEs and the onset of subclinical atherosclerosis. METHODS: We designed a single centre, bias-adjusted, prospective, observational study to investigate, in a homogeneous subset of RA patients, the occurrence of new onset of CVEs and subclinical atherosclerosis...
2017: PloS One
https://www.readbyqxmd.com/read/28103134/the-role-of-nuclear-factor-of-activated-t-cells-in-pulmonary-arterial-hypertension
#4
Rui Chen, Jinchuan Yan, Peijing Liu, Zhongqun Wang, Cuiping Wang, Wei Zhong, Liangjie Xu
Nuclear factor of activated T cells (NFAT) was first identified as a transcription factor about three decades ago and was not well studied until the development of immunosuppressant. Numerous studies confirm that calcineurin/NFAT signaling is very important in the development of vasculature and cardiovascular system during embryogenesis and is involved in the development of vascular diseases such as hypertension, atherosclerosis and restenosis. Recent studies demonstrated that NFAT proteins also regulate immune response and vascular cells in the pulmonary microenvironment...
January 19, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28102478/influence-of-inflammation-and-atherosclerosis-in-atrial-fibrillation
#5
REVIEW
Rose Mary Ferreira Lisboa da Silva
BACKGROUND: Inflammation markers have been associated with cardiovascular diseases including atrial fibrillation. This arrhythmia is the most frequent, with an incidence of 38/1000 person-years. PURPOSE OF REVIEW: The aims of this study are to discuss the association between inflammation, atherosclerosis and atrial fibrillation and its clinical implications. Atherosclerosis is a chronic inflammatory disease and inflammation is a triggering factor of atherosclerotic plaque rupture...
January 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28100872/serum-monokine-induced-by-gamma-interferon-is-associated-with-severity-of-coronary-artery-disease
#6
Youfeng Liang, Chun Yang, Qi Zhou, Wenbo Pan, Wansheng Zhong, Ruyue Ding, Ailing Wang
The immune system may play important roles in the pathogenesis of cardiovascular disease. T-cell mediated immune responses in human progression of atherosclerotic disease and hypertension have recently been revealed, but the significance of T-cell specific chemokines in coronary artery heart disease has not been confirmed. In our study, we sought to examine the association between serum levels of the monokine induced by gamma interferon (MIG)/CXCL9 and the severity of coronary artery disease. We studied 117 patients with coronary heart disease and 80 patients with no coronary heart disease...
January 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28100853/antioxidant-and-antimicrobial-properties-of-bioactive-phytochemicals-from-cranberry
#7
Monika Baranowska, Agnieszka Bartoszek
In the rational human diet, the important role of fruits and vegetables, which are a source of bioactive phytochemicals, is emphasized. Among fruits particular attention, due to a number of documented health-promoting properties, is focused on cranberry. This fruit is characterized by the high content of antioxidant phenolic compounds, which may support the natural antioxidant defense system of the body in the prevention of damage caused by oxidative stress induced by reactive oxygen species (ROS). Therefore, cranberry is suggested for the prevention of civilization diseases such as atherosclerosis, hypertension and cancer, whose etiology is associated directly with oxidative stress...
December 31, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28093411/age-and-sex-related-influences-on-left-ventricular-mechanics-in-elderly-individuals-free-of-prevalent-heart-failure-the-aric-study-atherosclerosis-risk-in-communities
#8
Chung-Lieh Hung, Alexandra Gonçalves, Amil M Shah, Susan Cheng, Dalane Kitzman, Scott D Solomon
BACKGROUND: Advanced age is related to left ventricular (LV) remodeling. We sought to investigate the relationships between aging, elevated hemodynamic load, cardiac mechanics, and LV remodeling in an elderly community-based population. METHODS AND RESULTS: We studied 1105 subjects (76±5 years, 61% women) without prevalent heart failure, who attended the visit 5 of the ARIC study (Atherosclerosis Risk in Communities). LV global longitudinal strain, global circumferential strain, and torsion indices were analyzed using 3-dimensional echocardiography...
January 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28092279/association-between-long-term-blood-pressure-control-and-ten-year-progression-in-carotid-arterial-stiffness-among-hypertensive-individuals-the-multiethnic-study-of-atherosclerosis
#9
Yacob G Tedla, Adam D Gepner, Dhananjay Vaidya, Laura Colangelo, James H Stein, Kiang Liu, Philip Greenland
BACKGROUND: Arterial stiffness was shown to be higher among hypertensive patients with diabetes than those without diabetes and among older than younger hypertensive patients. We examined whether the association between long-term blood pressure (BP) control and 10-year progression in carotid arterial stiffness varies by diabetes status and age. METHODS: Participants were 906 individuals with hypertension at baseline and three follow-up visits in the Multi-Ethnic Study of Atherosclerosis (mean age 63...
January 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28089168/the-relationship-between-dietary-intake-and-other-cardiovascular-risk-factors-with-blood-pressure-in-individuals-without-a-history-of-a-cardiovascular-event-evidence-based-study-with-5670-subjects
#10
Mohsen Mazidi, Mohsen Nematy, Ali Reza Heidari-Bakavoli, Zahra Namadchian, Majid Ghayour-Mobarhan, Gordon A Ferns
BACKGROUND AND AIM: Raised blood pressure is a leading cause of morbidity and mortality worldwide; improved nutritional approaches to population-wide prevention are required.We aimed to investigate the relationship between dietary intake and other cardiovascular risk factors with blood pressure in individuals without a history of a cardiovascular event in an Iranian cohort. MATERIAL AND METHOD: A cross-sectional study of 5670 healthy subjects [approximately 40% (n=2179) males and 60% (n=3491) females] was undertaken in a sample from northeastern Iran...
December 9, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28088517/osborne-mendel-rats-simultaneously-develop-cardiac-and-renal-dysfunction-left-atrial-thrombosis-peripheral-artery-occlusion-and-ascending-aortic-dissection
#11
Makoto Asahina, Hideki Matsumoto, Yoshitaka Yasuhara, Noriko Suzuki, Ritsuko Takami, Michiyasu Takeyama, Ryuichi Tozawa
Although chronic kidney disease (CKD) is strongly associated with onsets of cardiovascular disease (CVD), the pathogenic mechanism between these diseases has not been fully understood. To develop and validate new therapeutic strategies for this complication, appropriate experimental models that reflect the complexity of the underlying pathophysiology are needed. The Osborne-Mendel (OM) rat was identified as an atherosclerosis-prone and a premature-death rat strain among 16 inbred rat strains when fed high-cholesterol containing diet...
January 11, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28078487/the-role-of-the-nox4-derived-ros-mediated-rhoa-rho-kinase-pathway-in-rat-hypertension-induced-by-chronic-intermittent-hypoxia
#12
Wen Lu, Jing Kang, Ke Hu, Si Tang, Xiufang Zhou, Lifang Xu, Yuanyuan Li, Shuhui Yu
BACKGROUND: Obstructive sleep apnea syndrome, which is a risk factor for resistant hypertension, is characterized by chronic intermittent hypoxia (CIH) and is associated with many cardiovascular diseases. CIH elicits systemic oxidative stress and sympathetic hyperactivity, which lead to hypertension. Rho kinases (ROCKs) are considered to be major effectors of the small GTPase RhoA and have been extensively studied in the cardiovascular field. Upregulation of the RhoA/ROCK signaling cascade is observed in various cardiovascular disorders, such as atherosclerosis, pulmonary hypertension, and stroke...
January 11, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28078262/the-leaf-of-diospyros-kaki-thumb-ameliorates-renal-oxidative-damage-in-mice-with-type-2-diabetes
#13
Myung-Sook Choi, Mi Ji Jeong, Yong Bok Park, Sang Ryong Kim, Un Ju Jung
Diabetic kidney disease is the most common and severe chronic complication of diabetes. The leaf of Diospyros kaki Thumb (persimmon) has been commonly used for herbal tea and medicinal purposes to treat a variety of conditions, including hypertension and atherosclerosis. However, the effect of persimmon leaf on kidney failure has not been investigated. This study aimed to examine the role of persimmon leaf in protecting the diabetes-associated kidney damage in a mouse model of type 2 diabetes. Mice were fed either a normal chow diet with or without powered persimmon leaf (5%, w/w) for 5 weeks...
December 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28076021/radiologic-assessment-of-native-renal-vasculature-a-multimodality-review
#14
Sayf Al-Katib, Monisha Shetty, Syed Mohammad A Jafri, Syed Zafar H Jafri
A wide range of clinically important anatomic variants and pathologic conditions may affect the renal vasculature, and radiologists have a pivotal role in the diagnosis and management of these processes. Because many of these entities may not be suspected clinically, renal artery and vein assessment is an essential application of all imaging modalities. An understanding of the normal vascular anatomy is essential for recognizing clinically important anatomic variants. An understanding of the protocols used to optimize imaging modalities also is necessary...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28068529/impact-of-high-dose-statins-on-vitamin-d-levels-and-platelet-function-in-patients-with-coronary-artery-disease
#15
Monica Verdoia, Patrizia Pergolini, Roberta Rolla, Matteo Nardin, Alon Schaffer, Lucia Barbieri, Veronica Daffara, Paolo Marino, Giorgio Bellomo, Harry Suryapranata, Giuseppe De Luca
BACKGROUND: Statins represent a pivotal treatment in coronary artery disease, offering a reduction in cardiovascular risk even beyond their lipid-lowering action. However, the mechanism of these "pleiotropic" benefits of statins is poorly understood. Vitamin D has been suggested as a potential mediator of the anti-inflammatory, anti-thrombotic and vascular protecting effects of statins. Aim of present study was to assess the impact of a high-intensity statin therapy on vitamin D levels and platelet function in patients with coronary artery disease...
December 28, 2016: Thrombosis Research
https://www.readbyqxmd.com/read/28068281/pathophysiological-role-of-adiponectin-leptin-and-asymmetric-dimethylarginine-in-the-process-of-atherosclerosis
#16
Daniela Iv Koleva, Maria M Orbetzova, Julia G Nikolova, Tanya I Deneva
Adipose tissue is recognized as a rich source of proinflammatory mediators that may directly contribute to vascular injury, insulin resistance, and atherogenesis. Many studies have shown that adiponectin has antiatherogenic and anti-inflammatory properties. Adiponectin acts not only as a factor increasing insulin sensitivity, and the protective effect may result from its ability to suppress production of proinflammatory cytokines. It negatively regulates the expression of TNF-alpha and C-reactive protein (CRP) in adipose tissue; reduces expression of vascular and intracellular adhesion molecules (VCAM-1, ICAM-1), E-selectin, interleukin-8 (IL-8)...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28063251/perivascular-adipose-tissue-inflammation-in-vascular-disease
#17
REVIEW
Ryszard Nosalski, Tomasz J Guzik
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular characteristics. PVAT dysfunction is characterized by its inflammatory character, oxidative stress, diminished production of vaso-protective adipocyte derived relaxing factors (ADRFs) and increased production of paracrine factors such as resistin, leptin, cytokines (IL-6, TNF-α) and chemokines (RANTES, MCP-1)...
January 7, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28059659/antiplatelet-therapy-for-the-prevention-of-peri-coiling-thromboembolism-in-high-risk-patients-with-ruptured-intracranial-aneurysms
#18
Nancy J Edwards, Wesley H Jones, Aditya Sanzgiri, Juan Corona, Mark Dannenbaum, Peng Roc Chen
OBJECTIVE The most frequent procedural complication of the endovascular treatment of intracranial aneurysms is a thromboembolic event (TEE); in a subset of patients, such events will cause permanent neurological disability. In patients with unruptured aneurysms, increasing evidence supports the use of periprocedural antiplatelet therapy to prevent TEEs. The object of this study was to evaluate whether patients with ruptured aneurysms and subarachnoid hemorrhage would also benefit from periprocedural antiplatelet therapy...
January 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28057794/purinergic-signaling-in-the-cardiovascular-system
#19
REVIEW
Geoffrey Burnstock
There is nervous control of the heart by ATP as a cotransmitter in sympathetic, parasympathetic, and sensory-motor nerves, as well as in intracardiac neurons. Centers in the brain control heart activities and vagal cardiovascular reflexes involve purines. Adenine nucleotides and nucleosides act on purinoceptors on cardiomyocytes, AV and SA nodes, cardiac fibroblasts, and coronary blood vessels. Vascular tone is controlled by a dual mechanism. ATP, released from perivascular sympathetic nerves, causes vasoconstriction largely via P2X1 receptors...
January 6, 2017: Circulation Research
https://www.readbyqxmd.com/read/28056529/anterior-tragal-crease-is-associated-with-atherosclerosis
#20
Pawinee Rerknimitr, Korbkarn Pongpairoj, Chanat Kumtornrat, Ratchathorn Panchaprateep, Cameron P Hurst, Aurauma Chutinet, Pravit Asawanonda, Nijasri C Suwanwela
The utility of the ear crease sign, anterior tragal crease (ATC), as a marker of atherosclerosis is yet to be established. The intima-media thickness of the common carotid artery (IMT-CCA) has been used as a noninvasive surrogate marker for atherosclerosis. History of traditional risk factors for atherosclerosis was obtained from 147 volunteers; ear examination was also performed and venous blood was drawn for laboratory analysis. The volunteers then underwent an ultrasonography measurement of the IMT-CCA. In univariate analysis, presence of ATC, age, underlying hypertension, diabetes mellitus, ischemic heart disease, cerebrovascular disease, cigarette smoking, low-density lipoprotein, and high-sensitivity C-reactive protein were significantly associated with the IMT-CCA...
January 1, 2017: Angiology
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