Meng-Ying Liu, Yixin Fan, Ningjie Ni, Tao Yu, Zhiyuan Mao, Hanyu Huang, Jing Zhang, Yulin Tang, Hongliang He, Fan Meng, Yongping You, Qi-Gang Zhou
BACKGROUND: Glucocorticoids (GCs) are steroidal hormones produced by the adrenal cortex. A physiological-level GCs have a crucial function in maintaining many cognitive processes, like cognition, memory, and mood, however, both insufficient and excessive GCs impair these functions. Although this phenomenon could be explained by the U-shape of GC effects, the underlying mechanisms are still not clear. Therefore, understanding the underlying mechanisms of GCs may provide insight into the treatments for cognitive and mood-related disorders...
February 2024: CNS Neuroscience & Therapeutics