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https://www.readbyqxmd.com/read/27905390/-pr%C3%B0-gnosis-of-motor-function-recovery-in-ischemic-stroke-using-diffusion-tensor-mri
#1
M Yu Maksimova, T A Popova, R N Konovalov
AIM: To identify factors of motor recovery in ischemic stroke (IS) using diffusion tensor imaging (DTI). MATERIAL AND METHODS: Forty-seven patients with IS were studied within 1-2, 7-8, 14-15, 20-21 days after stroke. The fractional anisotropy (FA) values of the pyramidal tract were measured in the posterior limb of the internal capsule, cerebral peduncle and pons. Relative values of FA (rFA) ratio (rFA=FA affected side/FA unaffected side) were assessed as well...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27903286/carrion-s-disease-an-eradicable-illness
#2
Cláudia Gomes, Maria J Pons, Juana Del Valle Mendoza, Joaquim Ruiz
Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion's disease in endemic areas, they make take into account due to they are the perpetuators of this disease...
December 1, 2016: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/27899612/ymdb-2-0-a-significantly-expanded-version-of-the-yeast-metabolome-database
#3
Miguel Ramirez-Gaona, Ana Marcu, Allison Pon, An Chi Guo, Tanvir Sajed, Noah A Wishart, Naama Karu, Yannick Djoumbou Feunang, David Arndt, David S Wishart
YMDB or the Yeast Metabolome Database (http://www.ymdb.ca/) is a comprehensive database containing extensive information on the genome and metabolome of Saccharomyces cerevisiae Initially released in 2012, the YMDB has gone through a significant expansion and a number of improvements over the past 4 years. This manuscript describes the most recent version of YMDB (YMDB 2.0). More specifically, it provides an updated description of the database that was previously described in the 2012 NAR Database Issue and it details many of the additions and improvements made to the YMDB over that time...
November 28, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27894344/siropins-novel-serine-protease-inhibitors-from-gut-microbiota-acting-on-human-proteases-involved-in-inflammatory-bowel-diseases
#4
Héla Mkaouar, Nizar Akermi, Vincent Mariaule, Samira Boudebbouze, Nadia Gaci, Florette Szukala, Nicolas Pons, Josan Marquez, Ali Gargouri, Emmanuelle Maguin, Moez Rhimi
BACKGROUND: In eukaryotes, the serpins constitute a wide family of protease inhibitors regulating many physiological pathways. Many reports stressed the key role of serpins in several human physiopathologies including mainly the inflammatory bowel diseases. In this context, eukaryotic serpins were largely studied and their use to limit inflammation was reported. In comparison to that, bacterial serpins and mainly those from human gut microbiota remain poorly studied. RESULTS: The two genes encoding for putative serpins from the human gut bacterium Eubacterium sireaum, display low sequence identities...
November 29, 2016: Microbial Cell Factories
https://www.readbyqxmd.com/read/27894222/-training-degree-assessment-of-staff-producing-parenteral-nutrition-in-pharmacy-services
#5
Rosa Mª Romero Jiménez, Pilar Gomis Muñoz, Cristina Crespo, Guadalupe Piñeiro, Juan Carlos Pérez-Pons, Sonsoles García Rodicio, Carmen Ripa Ciaurriz, Vicente Gimeno Ballester, Cristina Vázquez, Mercedes Cervera, Mª Victoria Calvo, Pilar Tejada
OBJECTIVE: To assess the level of expertise of Pharmacy personnel in the manufacturing of total parenteral nutrition. MATERIAL AND METHODS: An on-line survey including 17 questions concerning key aspects of TPN manufacturing was designed. Survey monkey software was used to create the survey and to analize its results. RESULTS: 135 answers were received. 95% of the participant Pharmacy services had written standard manufacturing procedures...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27891663/extended-release-niacin-increases-anti-apoa-i-antibodies-that-block-the-anti-oxidant-effect-of-hdl-c-the-explore-clinical-trial
#6
J R Batuca, M C Amaral, C Favas, F S Paula, P R J Ames, A L Papoila, J Delgado Alves
AIMS: Extended Release-Niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN was associated with the production of antibodies against HDL (aHDL) and apolipoprotein A-I (aApoA-I). METHODS: Twenty-one patients older than 18 years, with HDL-C ≤ 40 mg/dL (men) or ≤ 50 mg/dL (women) were randomly assigned to receive daily ERN (n = 10) or placebo (n = 11) for two sequential 12-week periods, with 4 weeks of wash-out before cross-over...
November 27, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27891523/5ht3-antagonists-versus-dexamethasone-in-the-prevention-of-ponv-in-patients-undergoing-laparoscopic-cholecystectomy-a-meta-analysis-of-rcts
#7
REVIEW
Chengmao Zhou, Yu Zhu, Zhen Liu, Lin Ruan
Background. 5HT3 antagonist, an antiemetic alternative to dexamethasone, is an effective drug for the prevention of postoperative nausea and vomiting (PONV). Methods. PubMed and The Cochrane Library (from inception to June 2016) were searched for relevant RCTs (randomized controlled trials). Results. Seven trials, totaling 682 patients, were included in this meta-analysis. This meta-analysis demonstrated that 5HT3 antagonist was as effective as dexamethasone in preventing PONV (RR, 1.12; 95% CI, [0.86, 1.45]; P = 0...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27890749/the-medial-and-lateral-lemnisci-anatomically-adjoined-but-functionally-distinct-fiber-tracts
#8
Ruben Rodríguez-Mena, Uğur Türe
OBJECTIVE: The dense and complex distribution of neural structures in the brain stem makes it challenging to understand their real configuration. We used the fiber microdissection technique to reveal the course of the medial and lateral lemnisci within the brain stem. Although these structures seem anatomically alike, they are functionally distinct. METHODS: Fifteen human brain stems and eight brain hemispheres (formalin-fixed and previously frozen) were dissected and studied under the operating microscope by applying the fiber microdissection technique...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27889843/a-randomized-comparison-of-the-ambu-auragain-versus-the-lma-supreme-in-patients-undergoing-gynaecologic-laparoscopic-surgery
#9
Ana M Lopez, Merce Agusti, Pedro Gambus, Montserrat Pons, Teresa Anglada, Ricard Valero
Second generation supraglottic airway devices providing high seal airway pressures are suitable for patients undergoing gynecologic laparoscopy. We compared the seal pressure achieved by the new Ambu AuraGain™ versus LMA Supreme™ following pneumoperitoneum in the Trendelenburg position. Sixty female patients were randomly allocated to ventilation with either the AuraGain or the Supreme. A target-controlled system was used to administer total intravenous anesthesia. Intracuff pressure was maintained below 60 cm H2O...
November 26, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27888745/feasibility-of-eliciting-the-h-reflex-in-the-masseter-muscle-in-patients-under-general-anesthesia
#10
Sedat Ulkatan, Ana Maria Jaramillo, Maria J Téllez, Robert R Goodman, Vedran Deletis
OBJECTIVE: To explore the feasibility of eliciting the brainstem H reflex in the masseter muscle in patients under general anesthesia. METHODS: We electrically stimulated the masseteric nerve, a branch of the trigeminal nerve, and recorded ipsilateral masseteric and temporalis muscle responses. We tested eight patients who presented with trigeminal neuralgia; one patient had a temporal bone tumor and one patient had a brainstem arteriovenous malformation. All responses were elicited when patients were under general anesthesia and before the initiation of surgery...
November 5, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27886392/deregulated-expression-of-ezh2-in-congenital-brainstem-disconnection
#11
P G Barth, E Aronica, S Fox, K Fluiter, M A J Weterman, A Poretti, D C Miller, E Boltshauser, B Harding, M Santi, F Baas
Congenital brainstem disconnection (CBSD) is an enigmatic embryo-fetal defect presenting as (sub)total absence of a segment between mesencephalon and lower brainstem. Rostro-caudal limits of the defect vary while the basal pons is always involved and the cerebellum is globally hypoplastic. A recent update and review[1] lists 14 cases, including 3 brain autopsy studies[1-3]. Necrosis and glial- or inflammatory reactions were absent. Inferior olivary nuclei were small or absent, pontine nuclei depleted, and the cerebellar dentate nuclei dysplastic...
November 25, 2016: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/27886072/peroxynitrite-sensor-based-on-a-screen-printed-carbon-electrode-modified-with-a-poly-2-6-dihydroxynaphthalene-film
#12
Ioana Silvia Hosu, Diana Constantinescu-Aruxandei, Maria-Luiza Jecu, Florin Oancea, Mihaela Badea Doni
For the first time the electropolymerization of 2,6-dihydroxynaphthalene (2,6-DHN) on a screen printed carbon electrode (SPCE) was investigated and evaluated for peroxynitrite (PON) detection. Cyclic voltammetry was used to electrodeposit the poly(2,6-DHN) on the carbon electrode surface. The surface morphology and structure of poly(2,6-DHN) film were investigated by SEM and FTIR analysis, and the electrochemical features by cyclic voltammetry. The poly(2,6-DHN)/SPCE sensor showed excellent electrocatalytic activity for PON oxidation in alkaline solutions at very low potentials (0-100 mV vs...
November 23, 2016: Sensors
https://www.readbyqxmd.com/read/27885675/intratissue-lymphovenous-communications-in-the-mechanism-of-action-of-vascularized-lymph-node-transfer
#13
María Miranda Garcés, Gemma Pons, Rosa Mirapeix, Jaume Masià
BACKGROUND AND OBJECTIVES: Vascularized lymph node transfer (VLNT) as a surgical treatment for cancer-related lymphedema has shown beneficial effects. The mechanism of action of this procedure involves lymphangiogenesis and lymphovenous communications (LVC) within the lymph nodes. We propose intratissue LVC as an additional element responsible for drainage of lymph to blood in the flap and examine this hypothesis in the current study. METHODS: This prospective study determined the passage of lymph to the venous system via intratissue LVC in 26 free flaps used for breast reconstruction...
November 25, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27884553/atlas-of-systematic-variation-in-renal-replacement-therapy-in-catalonia-2002-2012
#14
Cristian Tebé Condomí, Emma Arcos, Jordi Comas, Mireia Espallargues, Joan M V Pons, Joan M Díaz, Jaume Tort, Alberto Martinez-Castelao
INTRODUCTION: Variations in the use of healthcare services can be defined as systematic variations of adjusted rates for certain aggregation levels of the population. The study analyses how renal replacement therapy (RRT) is used, identifying RRT variability in Catalonia from 2002 to 2012. MATERIAL AND METHODS: Ecological study by health area using data from the Catalan renal registry. We present incident rates, standardised incidence ratios and prevalence, while variability was calculated through direct and indirect standardisation methods...
November 21, 2016: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/27882183/psychiatric-symptoms-and-limb-tremors-associated-with-central-pontine-myelinolysis-a-case-of-alcoholism-without-hyponatremia
#15
Xue-Min Feng, Teng Zhao, Chun-Kui Zhou, Jing-Yao Liu
Central pontine myelinolysis (CPM), also known as osmotic demyelination syndrome, is a rare demyelinating disorder characterized by the loss of myelin in the center of the basis pontis. In this case report, an alcoholic patient with CPM and acquired demyelinating lesion of the basis pontis is described. The patient is a 70 year-old woman who presented with intermittent psychiatric symptoms and limb tremors following two months of alcohol abuse. During admission, magnetic resonance imaging (MRI) revealed hyperintensity on T2 weighted images and fluid-attenuated inversion-recovery imaging in the central pons without contrast enhancement...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27881290/mercury-eicosapentanoic-acid-and-docosahexaenoic-acid-demonstrate-limited-effect-on-plasma-paraoxonase-1-activity-and-blood-pressure-among-avid-seafood-consumers-in-the-long-island-study-of-seafood-consumption-ny-usa
#16
Charles Miller, Roxanne Karimi, Qiao Zhang, Jie Yang, Jaymie Meliker
BACKGROUND AND AIM: Moderate fish consumption is recommended for prevention of coronary heart disease (CHD) as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have known beneficial effects on risk factors such as reducing blood pressure (BP) and increasing paraoxonase-1 (PON-1) activity. However concomitant methylmercury (MeHg) exposure from fish consumption may mitigate these benefits and the net effect on BP and PON-1 activity has not been extensively studied in western populations consuming diverse seafood types...
November 17, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27880004/causal-relationships-among-neurons-of-the-nucleus-incertus-and-the-hippocampal-theta-activity-in-the-rat
#17
Sergio Martínez-Bellver, Ana Cervera-Ferri, Aina Luque-García, Joana Martínez-Ricós, Alfonso Valverde-Navarro, Manuel Bataller, Juan Guerrero, Vicent Teruel-Marti
In recent years, a body of evidence has shown that the nucleus incertus (NI), in the dorsal tegmental pons, is a key node of the brainstem circuitry involved in hippocampal theta rhythmicity. Ascending reticular brainstem system activation evokes hippocampal theta rhythm with coupled neuronal activity in the NI. In a recent paper, we showed three populations of neurons in the NI with differential firings during hippocampal theta activation. The objective of this work is to better evaluate the causal relationship between the activity of NI neurons and the hippocampus during theta activation in order to further understand the role of the NI in the theta network...
November 23, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27879473/an-unusual-cause-of-tinnitus-essential-palatal-myoclonus
#18
Stanislas Ballivet de Régloix, A Marhic, Y Pons
No abstract text is available yet for this article.
November 22, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27878751/assessment-of-the-relationship-between-serum-paraoxonase-activity-and-epicardial-adipose-tissue-in-hemodialysis-patients
#19
Emad Abdallah, Samya El-Shishtawy, Nevine Sherif, Ahmed Ali, Omnia El-Bendary
PURPOSE: Paraoxonase-1 (PON-1) is a high-density lipoprotein-associated (HDL) enzyme, which has been shown to reduce susceptibility to low-density lipoprotein (LDL) peroxidation. Epicardial adipose tissue (EAT) is a marker of atherosclerosis. The aim of this study was to determine the relationship between PON-1 activity and EAT in hemodialysis (HD) patients. METHODS: This is a cross-sectional study conducted on 72 (43 males) HD patients with end-stage renal disease...
November 23, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27878369/youtube-videos-on-oral-care-of-the-organ-or-hematopoietic-stem-cell-transplant-patients
#20
Pia López-Jornet, Eduardo Pons-Fuster, Juan Antonio Ruiz-Roca
OBJECTIVE: Video-sharing websites can be a useful platform for disseminating information. The aim of this study was to evaluate information about the oral health care of the organ transplant and hematopoietic stem cell transplant patients available on YouTube™. METHODS: The transversal study evaluated the content of YouTube™ videos. The videos were located by entering key search terms in the YouTube™ search engine-oral care/dental management/organ transplant/hematopoietic stem cell transplant patients...
November 22, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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