keyword
MENU ▼
Read by QxMD icon Read
search

Early puberty

keyword
https://www.readbyqxmd.com/read/27900926/-corneal-cross-linking-as-a-treatment-for-progressive-keratoconus
#1
R P L Wisse, N Soeters, D A Godefrooij, N G de Koning-Tahzib
Keratoconus is a corneal disease with onset typically occurring during puberty or early adulthood. The cornea progressively thins and acquires a cone-like shape which negatively affects visual acuity. In the early stages, visual acuity can be corrected with glasses or contact lenses. In more advanced cases, a corneal transplant is ultimately indicated to restore visual acuity. Corneal cross-linking (CXL) is a treatment given at a relatively early stage that protects patients against deterioration of visual acuity and further corneal deformation in progressive cases of keratoconus...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27898892/transcriptome-analyses-identify-five-transcription-factors-differentially-expressed-in-the-hypothalamus-of-post-versus-prepubertal-brahman-heifers
#2
M R S Fortes, L T Nguyen, M M D C A Weller, A Cánovas, A Islas-Trejo, L R Porto-Neto, A Reverter, S A Lehnert, G B Boe-Hansen, M G Thomas, J F Medrano, S S Moore
Puberty onset is a developmental process influenced by genetic determinants, environment, and nutrition. Mutations and regulatory gene networks constitute the molecular basis for the genetic determinants of puberty onset. The emerging knowledge of these genetic determinants presents opportunities for innovation in the breeding of early pubertal cattle. This paper presents new data on hypothalamic gene expression related to puberty in (Brahman) in age- and weight-matched heifers. Six postpubertal heifers were compared with 6 prepubertal heifers using whole-genome RNA sequencing methodology for quantification of global gene expression in the hypothalamus...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27897024/-peripheral-precocious-puberty
#3
J Zvonařová Skalická, R Pilka
OBJECTIVE: To summarize literature data on peripheral precocious puberty. DESIGN: A literature review. SETTING: Středomoravská nemocniční a.s., hospital Šternberk, Department of Obstetrics and Gynaecology, University Hospital, Medical Faculty, Palacky University, Olomouc. METHODS AND RESULTS: We searched in PubMed using the key words stated below according to date and published since 1980.Peripheral precocious puberty occurs in girls with the frequency 1:400-1000...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27887945/kisspeptin-system-in-pejerrey-fish-odontesthes-bonariensis-characterization-and-gene-expression-pattern-during-early-developmental-stages
#4
M Oswaldo Tovar Bohórquez, Alejandro S Mechaly, Lily C Hughes, Daniela Campanella, Guillermo Ortí, Luis F Canosa, Gustavo M Somoza
In vertebrates, kisspeptins and their receptors are known to be related to puberty onset and gonadal maturation, however, there are few studies concerning their role in early development. Here, we characterize the kisspeptin system in the pejerrey, Odontesthes bonariensis, a fish with strong temperature-dependent sex determination. We reconstructed the phylogenetic history of the two ligands (kiss1 and kiss 2) and two receptors (kissr2 and kissr3) in pejerrey in the context of recent classifications of bony fishes, determined their tissue distribution and documented the early expression pattern of these ligands and receptors...
November 22, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27870401/sex-differences-in-hippocampal-function
#5
REVIEW
Wendy A Koss, Karyn M Frick
Sex differences in the function of the hippocampus have been observed in numerous mammalian species. However, the magnitude, extent, and specificity of these differences are unclear because they can depend on factors including age, methodology, and environment. This Review will discuss seminal studies examining sex differences in hippocampal memory, neuronal morphology, synaptic plasticity, and cell signaling in humans and rodents. We also describe possible organizational and activational effects of sex steroid hormones during early development, puberty, and adulthood that may lead to sex differences observed in the hippocampus...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27866050/boucher-neuh%C3%A3-user-syndrome-a-rare-cause-of-inherited-hypogonadotropic-hypogonadism-a-case-of-two-adult-siblings-with-two-novel-mutations-in-pnpla6
#6
Jakob H Langdahl, Anja L Frederiksen, Nina Nguyen, Klaus Brusgaard, Claus B Juhl
Boucher Neuhäuser Syndrome (BNS) is a rare clinical syndrome with autosomal recessive inheritance defined by early-onset ataxia, hypogonadism and chorioretinal dystrophy. We present two siblings diagnosed with BNS in late adult life identified with compound heterozygous state of two novel PNPLA6 mutations. Five healthy siblings were non- or heterozygous carriers of the mutations. The cases, which presented with ataxia in childhood and hypogonadotropic hypogonadism (HH), were diagnosed at age 17 and 25, respectively, when examined for delayed puberty...
November 16, 2016: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/27859946/impact-of-childhood-asthma-on-growth-trajectories-in-early-adolescence-findings-from-the-childhood-asthma-prevention-study-caps
#7
Maria Movin, Frances L Garden, Jennifer L P Protudjer, Vilhelmina Ullemar, Frida Svensdotter, David Andersson, Andreas Kruse, Chris T Cowell, Brett G Toelle, Guy B Marks, Catarina Almqvist
BACKGROUND AND OBJECTIVE: Understanding the associations between childhood asthma and growth in early adolescence by accounting for the heterogeneity of growth during puberty has been largely unexplored. The objective was to identify sex-specific classes of growth trajectories during early adolescence, using a method which takes the heterogeneity of growth into account and to evaluate the association between childhood asthma and different classes of growth trajectories in adolescence...
November 8, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27845188/anxiety-and-depressive-like-profiles-during-early-and-mid-adolescence-in-the-female-wistar-kyoto-rat
#8
Deepthi D'Souza, Monika Sadananda
Approaches for the development of preclinical models of depression extensively use adult and male animals owing to the discrepancies arising out of the hormonal flux in adult females and adolescents during attainment of puberty. Thus the increased vulnerability of females towards clinical depression and anxiety-related disorders remains incompletely understood. Development of clinical models of depression in adolescent females is essential in order to evolve effective treatment strategies for adolescent depression...
November 11, 2016: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/27836531/childhood-sexual-abuse-and-early-timing-of-puberty
#9
Jennie G Noll, Penelope K Trickett, Jeffrey D Long, Sonya Negriff, Elizabeth J Susman, Idan Shalev, Jacinda C Li, Frank W Putnam
PURPOSE: The purpose was to examine whether the timing of puberty, indexed by breast development and pubic hair development, was earlier for sexually abused females compared with a matched comparison group of nonabused females, controlling for key alternative confounds. METHODS: A cohort of sexually abused females and matched comparisons was followed longitudinally at mean ages 11 through 20 years. Sexually abused participants (N = 84) were referred by protective services...
November 8, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27830573/developmental-contributors-to-trauma-response-the-importance-of-sensitive-periods-early-environment-and-sex-differences
#10
Jennifer S Stevens, Sanne J H van Rooij, Tanja Jovanovic
This review considers early factors that interact with development to contribute to later trauma responses, including developmental sensitive periods, the effects of early environment, and the emergence of sex differences. We also describe development of neural substrates that have been associated with posttraumatic stress disorder and specifically focus on fear behavior and circuitry. Emerging evidence suggests that there may be developmental shifts around age 10 in these underlying circuits that may contribute to vulnerability...
November 10, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27829479/metabolic-and-reproductive-characteristics-of-replacement-beef-heifers-subjected-to-an-early-weaning-regimen-involving-high-concentrate-feeding
#11
A L Zezeski, V L McCracken, R K Poole, A Al Naib, J K Smith, M A McCann, M L Rhoads
In an effort to better understand the consequences of early weaning (EW) for replacement beef heifers, a two-phase experiment was conducted investigating the impact on metabolic function and documenting reproductive characteristics. In phase 1, Angus×Simmental heifers (n=35) were stratified by BW and sire, and randomly assigned to either a normal weaning (NW, n=18) or EW (n=17) treatment. EW heifers were weaned at 107±3 days of age and provided access to a concentrate-based ration ad libitum with limit-fed mixed grass hay...
November 10, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27825136/pubertal-and-adult-windows-of-susceptibility-to-a-high-animal-fat-diet-in-trp53-null-mammary-tumorigenesis
#12
Yirong Zhu, Mark D Aupperlee, Yong Zhao, Ying Siow Tan, Erin L Kirk, Xuezheng Sun, Melissa A Troester, Richard C Schwartz, Sandra Z Haslam
Premenopausal breast cancer is associated with increased animal fat consumption among normal weight, but not overweight women (Farvid et al., 2014). Our previous findings in obesity-resistant BALB/c mice similarly showed promotion of carcinogen-induced mammary tumorigenesis by a diet high in saturated animal fat (HFD). This effect was specific to pubertal versus adult HFD. This study identifies the effects of HFD during puberty versus adulthood in Trp53-null transplant BALB/c mice and investigates its mechanism of enhancing tumorigenesis...
November 4, 2016: Oncotarget
https://www.readbyqxmd.com/read/27821898/congenital-adrenal-hyperplasia-due-to-11-beta-hydroxylase-deficiency-description-of-a-new-mutation-r384x
#13
Audrey Mary Matallana-Rhoades, Juan David Corredor-Castro, Francisco Javier Bonilla-Escobar, Bony Valentina Mecias-Cruz, Liliana Mejia de Beldjena
CASE DESCRIPTION: It is presented the phenotype of a new compound heterozygous mutation of the genes R384X and Q356X encoding the enzyme of 11-beta-hydroxylase. CLINICAL FINDINGS: Severe virilization, peripheral hypertension, and early puberty. TREATMENT AND OUTCOME: Managed with hormone replacement therapy (corticosteroid) and antihypertensive therapy (beta-blocker), resulting in the control of physical changes and levels of arterial tension...
September 30, 2016: Colombia Médica: CM
https://www.readbyqxmd.com/read/27814495/recollections-of-puberty-and-disordered-eating-in-young-women
#14
Sarah R Moore, Kirsten M P McKone, Jane Mendle
Puberty begins a period of vulnerability for disordered eating that is maintained and amplified through adolescence and early adulthood. In the present study, we test the association between young women's recollections of physical maturation and disordered eating outcomes in early adulthood. Participants comprised N = 421 female undergraduate students at a large, northeastern university in the United States (Mage = 19.7 years). Three models assessed the relative contributions of recollected puberty (perceptions of changes and preparedness, and timing of puberty), current contextual (social support, romantic bond, sorority or sport participation), and demographic (race, socioeconomic status, family structure) variables to three eating-disorder outcomes...
October 28, 2016: Journal of Adolescence
https://www.readbyqxmd.com/read/27810442/do-boys-eat-better-than-girls-in-india-longitudinal-evidence-on-dietary-diversity-and-food-consumption-disparities-among-children-and-adolescents
#15
Elisabetta Aurino
This paper examines the dynamics of gender-based disparities in the intra-household allocation of food during childhood and adolescence in Andhra Pradesh and Telangana by using three rounds of longitudinal data from two cohorts. While boys are advantaged at all ages (except for the Younger Cohort at 12 years old), the pro-boy gap widens markedly at 15 years old. Specifically, mid-adolescent girls tend to consume fewer protein- and vitamin-rich foods such as eggs, legumes, root vegetables and fruit. This result is robust to gender differences between adolescents in terms of puberty onset, school enrolment, time use and dietary behaviours...
October 27, 2016: Economics and Human Biology
https://www.readbyqxmd.com/read/27803155/bridging-the-gap-metabolic-and-endocrine-care-of-patients-during-transition
#16
REVIEW
Anita Hokken-Koelega, Aart-Jan van der Lely, Berthold Hauffa, Gabriele Häusler, Gudmundur Johannsson, Mohamad Maghnie, Jesús Argente, Jean DeSchepper, Helena Gleeson, John W Gregory, Charlotte Höybye, Fahrettin Keleştimur, Anton Luger, Hermann L Müller, Sebastian Neggers, Vera Popovic-Brkic, Eleonora Porcu, Lars Sävendahl, Stephen Shalet, Bessie Spiliotis, Maithé Tauber
OBJECTIVE: Seamless transition of endocrine patients from the paediatric to adult setting is still suboptimal, especially in patients with complex disorders, i.e., small for gestational age, Turner or Prader-Willi syndromes; Childhood Cancer Survivors, and those with childhood-onset growth hormone deficiency. METHODS: An expert panel meeting comprised of European paediatric and adult endocrinologists was convened to explore the current gaps in managing the healthcare of patients with endocrine diseases during transition from paediatric to adult care settings...
November 2016: Endocrine Connections
https://www.readbyqxmd.com/read/27796946/overview-of-mammary-gland-development-a-comparison-of-mouse-and-human
#17
Sara McNally, Torsten Stein
The mouse mammary gland is widely used as a model for human breast cancer and has greatly added to our understanding of the molecular mechanisms involved in breast cancer development and progression. To fully appreciate the validity and limitations of the mouse model, it is essential to be aware of the similarities and also the differences that exist between the mouse mammary gland and the human breast. This introduction therefore describes the parallels and contrasts in mouse mammary gland and human breast morphogenesis from an early embryonic phase through to puberty, adulthood, pregnancy, parturition, and lactation, and finally the regressive stage of involution...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27795999/effects-of-the-insulin-like-growth-factor-pathway-on-the-regulation-of-mammary-gland-development
#18
REVIEW
Woo Tae Ha, Ha Yeon Jeong, Seung Yoon Lee, Hyuk Song
The insulin-like growth factor (IGF) pathway is a key signal transduction pathway involved in cell proliferation, migration, and apoptosis. In dairy cows, IGF family proteins and binding receptors, including their intracellular binding partners, regulate mammary gland development. IGFs and IGF receptor interactions in mammary glands influence the early stages of mammogenesis, i.e., mammary ductal genesis until puberty. The IGF pathway includes three major components, IGFs (such as IGF-I, IGF-II, and insulin), their specific receptors, and their high-affinity binding partners (IGF binding proteins [IGFBPs]; i...
September 2016: Balsaeng'gwa Saengsig
https://www.readbyqxmd.com/read/27794483/anxiety-like-behaviors-in-adulthood-are-altered-in-male-but-not-female-rats-exposed-to-low-dosages-of-polychlorinated-biphenyls-in-utero
#19
Ross Gillette, Michael P Reilly, Viktoria Y Topper, Lindsay M Thompson, David Crews, Andrea C Gore
Exposure to polychlorinated biphenyls (PCBs), a class of endocrine-disrupting chemicals, can result in altered reproductive behavior in adulthood, especially when exposure occurs during critical periods of brain sexual differentiation in the fetus. Whether PCBs alter other sexually dimorphic behaviors such as those involved in anxiety is poorly understood. To address this, pregnant rat dams were injected twice, on gestational days 16 and 18, with the weakly estrogenic PCB mixture Aroclor 1221 (A1221) at one of two low dosages (0...
October 26, 2016: Hormones and Behavior
https://www.readbyqxmd.com/read/27789461/hypopituitarism-in-children-with-cerebral-palsy
#20
REVIEW
Suma Uday, Nick Shaw, Ruth Krone, Jeremy Kirk
Poor growth and delayed puberty in children with cerebral palsy is frequently felt to be related to malnutrition. Although growth hormone deficiency is commonly described in these children, multiple pituitary hormone deficiency (MPHD) has not been previously reported. We present a series of four children with cerebral palsy who were born before 29 weeks gestation who were referred to the regional endocrinology service, three for delayed puberty and one for short stature, in whom investigations identified MPHD...
October 27, 2016: Archives of Disease in Childhood
keyword
keyword
32698
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"