keyword
MENU ▼
Read by QxMD icon Read
search

Early puberty

keyword
https://www.readbyqxmd.com/read/28324034/anti-mullerian-hormone-and-ovarian-morphology-in-women-with-isolated-hypogonadotropic-hypogonadism-kallmann-syndrome-effects-of-recombinant-human-fsh
#1
Hélène Bry-Gauillard, Florence Larrat-Ledoux, Jean-Marc Levaillant, Nathalie Massin, Luigi Maione, Isabelle Beau, Nadine Binart, Philippe Chanson, Sylvie Brailly-Tabard, Janet E Hall, Jacques Young
Context: Isolated hypogonadotropic hypogonadism (IHH), characterized by gonadotropin deficiency and absent puberty, is very rare in women. IHH prevents pubertal ovarian stimulation, but anti-Mullerian hormone (AMH) and antral follicle count (AFC), have not been studied. Objectives: 1) Compare, in IHH versus controls, AMH, ovarian volume (OV) and AFC. 2) Compare in IHH, ovarian responses to recombinant human FSH (rhFSH) and rhFSH plus rhLH. Subjects: 68 IHH women, 51 matched healthy women...
January 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28301839/early-programming-of-obesity-throughout-the-life-course-a-metabolomics-perspective
#2
Sebastian Rauschert, Franca F Kirchberg, Linda Marchioro, Berthold Koletzko, Christian Hellmuth, Olaf Uhl
BACKGROUND: Over the last decades, research on early life risk factors for obesity and its comorbidities in early life has gained attention within the field of developmental origins of health and diseases. Metabolomics studies that are trying to find early life biomarker and intervention targets for the early development of obesity and associated cardiovascular diseases could help break the inter-generational cycle of obesity. SUMMARY: Metabolomics studies in the field of early programming are scarce and causality is lacking at this stage, as most of the studies are cross-sectional...
March 17, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28290112/protecting-bone-health-in-pediatric-rheumatic-diseases-pharmacological-considerations
#3
REVIEW
Yujuan Zhang, Diana Milojevic
Bone health in children with rheumatic conditions may be compromised due to several factors related to the inflammatory disease state, delayed puberty, altered life style, including decreased physical activities, sun avoidance, suboptimal calcium and vitamin D intake, and medical treatments, mainly glucocorticoids and possibly some disease-modifying anti-rheumatic drugs. Low bone density or even fragility fractures could be asymptomatic; therefore, children with diseases of high inflammatory load, such as systemic onset juvenile idiopathic arthritis, juvenile dermatomyositis, systemic lupus erythematosus, and those requiring chronic glucocorticoids may benefit from routine screening of bone health...
March 13, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28279175/the-mouse-mammary-gland-as-a-sentinel-organ-distinguishing-control-populations-with-diverse-environmental-histories
#4
SriDurgaDevi Kolla, Aastha Pokharel, Laura N Vandenberg
BACKGROUND: There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the laboratory is challenging, especially when their source is unknown. Unfortunately, EDC contaminations can interfere with the interpretation of data during toxicological evaluations. We propose that the male CD-1 mouse mammary gland is a sensitive bioassay to evaluate the inadvertent contamination of animal colonies...
March 9, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28271078/time-correlation-between-mononucleosis-and-initial-symptoms-of-ms
#5
John Endriz, Peggy P Ho, Lawrence Steinman
OBJECTIVE: To determine the average age of MS onset vs the age at which Epstein-Barr infection has previously occurred and stratify this analysis by sex and the blood level of Epstein-Barr nuclear antigen 1 (EBNA1) antibody. METHODS: Using infectious mononucleosis (IM) as a temporal marker in data from the Swedish epidemiologic investigation of MS, 259 adult IM/MS cases were identified and then augmented to account for "missing" childhood data so that the average age of MS onset could be determined for cases binned by age of IM (as stratified by sex and EBNA1 titer level)...
May 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28259093/exposure-to-phytoestrogens-in-utero-and-age-at-menarche-in-a-contemporary-british-cohort
#6
Kristin J Marks, Terryl J Hartman, Ethel V Taylor, Michael E Rybak, Kate Northstone, Michele Marcus
Phytoestrogens are estrogenic compounds that occur naturally in plants. Phytoestrogens can cross the placenta, and animal studies have found associations between in utero exposure to phytoestrogens and markers of early puberty. We investigated the association between in utero exposure to phytoestrogens and early menarche (defined as <11.5 years of age at onset) using data from a nested case-control study within the Avon Longitudinal Study of Parents and Children, a longitudinal study involving families living in the South West of England...
March 1, 2017: Environmental Research
https://www.readbyqxmd.com/read/28248755/testicular-growth-and-development-in-puberty
#7
Jaakko J Koskenniemi, Helena E Virtanen, Jorma Toppari
PURPOSE OF REVIEW: To describe pubertal testicular growth in humans, changes in testicular cell populations that result in testicular growth, and the role of testosterone and gonadotrophins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in testicular growth. When human data were not available, studies in nonhuman primates and/or rodents were used as surrogates. RECENT FINDINGS: Testicular growth in puberty follows a sigmoidal growth curve, with a large variation in timing of testicular growth and adult testicular volume...
February 28, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/28245188/amh-levels-in-girls-with-various-pubertal-problems
#8
Senay Savas-Erdeve, Elif Sagsak, Meliksah Keskin, Semra Cetinkaya, Zehra Aycan
BACKGROUND: Anti-Müllerian hormone (AMH) is produced by granulosa cells surrounding follicles that have undergone recruitment from the primordial follicle pool but have not been selected for dominance (preantral and early antral follicles). In healthy girls, serum levels of AMH vary considerably between individuals. We aimed to evaluate the AMH level in girls with premature thelarche (PT) and central precocious puberty (CPP). METHODS: Girls with CPP (n=21), PT (n=24) and a control prepubertal group (n=22) were included in the study...
March 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28245038/kraftig-%C3%A3-kning-av-k%C3%A3-nsdysfori-bland-barn-och-unga-tidigt-insatt-behandling-ger-betydligt-b%C3%A3-ttre-prognos
#9
Louise Frisén, Olle Söder, Per-Anders Rydelius
Dramatic increase of gender dysphoria in youth In the past decade there has been a dramatic increase in the number of young people with gender dysphoria seeking help for gender-confirming medical interventions. From a situation of no more than a few patients annually, there were almost 200 referrals of gender dysphoria to the Astrid Lindgren Children's Hospital in 2016. This child and adolescent psychiatric unit has the whole country as a catchment area for patients <16 years. Gender-confirming medical interventions are regulated by a special law that sets a minimum age for legal and surgical gender reassignment to 18 years...
February 22, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28240757/-anti-m%C3%A3-llerian-hormone-a-brief-review-of-the-literature
#10
G Ozzola
BACKGROUND: Anti-Müllerian hormone (AMH) is a dimeric glycoprotein, which was originally identified because of its role in male sexual differentiation. In fact, AMH is expressed by the Sertoli cellsof the foetal testes and induces the regression of the Müllerian ducts. In the absence of AMH, the Müllerian ducts evolve in the uterus, fallopian tubes and in the upper part of the vagina. In women AMH is produced by granulose cells, pre-antral and antral follicles and its major physiological role in the ovaries seems to be limited to inhibiting the development of the earliest stages of follicular development...
January 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28239958/differential-sex-effects-of-systolic-blood-pressure-and-ldl-c-on-type-2-diabetes-life-course-data-from-the-bogalusa-heart-study
#11
Benjamin D Pollock, Wei Chen, Emily W Harville, Tian Shu, Vivian Fonseca, Franck Mauvais-Jarvis, Tanika N Kelly, Lydia A Bazzano
BACKGROUND: There may be sex-specific cardiometabolic mechanisms early in life that affect the development of type 2 diabetes (T2DM) through mid-adulthood. Yet, there have been few studies examining whether early life-course interactions between cardiometabolic risk factors and sex are associated with incident T2DM. METHODS: We followed n = 7,725 children from the Bogalusa Heart Study through mid-adulthood to examine whether low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), body mass index (BMI), or systolic blood pressure (SBP) differentially impact the risk of T2DM for females versus males...
February 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28238455/androgen-dependent-mechanisms-of-pro-angiogenic-networks-in-placental-and-tumor-development
#12
Veronika M Metzler, Simone de Brot, Robert S Robinson, Jennie N Jeyapalan, Emad Rakha, Thomas Walton, David S Gardner, Emma F Lund, Jonathan Whitchurch, Daisy Haigh, Jack M Lochray, Brian D Robinson, Cinzia Allegrucci, Rupert G Fray, Jenny L Persson, Niels Ødum, Regina R Miftakhova, Albert A Rizvanov, Ieuan A Hughes, Rieko Tadokoro-Cuccaro, David M Heery, Catrin S Rutland, Nigel P Mongan
The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy, whereas in tumors establishing new blood supplies is considered a key step in supporting metastases. Therefore the development of novel angiogenesis inhibitors has been an area of active research in oncology. A subset of the molecular processes regulating angiogenesis are well understood in the context of both early placentation and tumorigenesis...
February 20, 2017: Placenta
https://www.readbyqxmd.com/read/28237342/changes-of-plasma-concentrations-of-insulin-like-peptide-3-and-testosterone-and-their-association-with-scrotal-circumference-during-pubertal-development-in-male-goats
#13
M A Hannan, N Kawate, Y Fukami, W W P N Weerakoon, E E Büllesbach, T Inaba, H Tamada
Insulin-like peptide 3 (INSL3) has been used as a testis-specific biomarker for puberty in several species, but the secretory profile of INSL3 during pubertal development in small ruminants is unknown. Here we sought to determine the age-related changes in the plasma concentrations of INSL3 and testosterone and their association with scrotal circumference during pubertal development in five male Shiba goats. Blood samples and scrotal circumference measurement were taken every 2 weeks from week 10 to week 52 of each goat's lifespan...
April 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28215580/deviant-peers-as-a-mediator-of-pubertal-timing-substance-use-associations-the-moderating-role-of-parental-knowledge
#14
Kristine Marceau, Kristina Jackson
PURPOSE: Early perceived pubertal timing and faster maturation have been linked to increased risk of adolescent substance use (SU), particularly for girls, but the mechanisms underlying this association are not well understood. We sought to replicate and extend findings from Westling et al. (2008) showing that peer deviance mediates the link between early puberty and SU with stronger pathways in the context of low parental knowledge of adolescents' whereabouts and activities. METHODS: Participants (n = 1,023; 52% female, 24% nonwhite, and 12% Hispanic) were recruited through middle schools...
February 15, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28215240/morningness-eveningness-correlates-with-sleep-time-quality-and-hygiene-in-secondary-school-students-a-multilevel-analysis
#15
Christian Vollmer, Konrad S Jankowski, Juan F Díaz-Morales, Heike Itzek-Greulich, Peter Wüst-Ackermann, Christoph Randler
At the onset of puberty, students shift their sleep to later hours, but school starts early. It is suggested that evening orientation and early school start times do not go well together. Therefore, the aim of this study was to investigate sleep problems in adolescence, and it was expected that the adolescents' eveningness orientation is associated with many sleep-related problems. Students of secondary education (n = 3201; mean = 13.8 ± 1.8 years) filled out a self-report questionnaire containing measures of morningness-eveningness, sleep time (midpoint of sleep, social "jetlag"), sleep length (on schooldays and on weekends), sleep quality, and sleep hygiene as well as questions on electronic screen media use...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28211649/insufficient-sleep-in-adolescents-causes-and-consequences
#16
Judith A Owens, Miriam R Weiss
Insufficient sleep poses an important and complicated set of health risks in the adolescent population. Not only is deficient sleep (defined as both sleep duration inadequate to meet sleep needs and sleep timing misaligned with the body's circadian rhythms) at epidemic levels in this population, but the contributing factors are both complex and numerous and there are a myriad of negative physical and mental health, safety and performance consequences. Causes of inadequate sleep identified in this population include internal biological processes such as the normal shift (delay) in circadian rhythm that occurs in association with puberty and a developmentally-based slowing of the "sleep drive", and external factors including extracurricular activities, excessive homework load, evening use of electronic media, caffeine intake and early school start times...
February 17, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28174478/scoliosis-in-adulthood-a-case-with-untreated-early-onset-scoliosis-presenting-at-the-age-of-76-years
#17
Hans-Rudolf Weiss
[Purpose] Untreated early-onset scoliosis may eventually progress to more than 90° after growth, cause severe health problems, and increase chance of mortality. Therefore, surgical intervention is often indicated prior to the development of a life-threatening deformity. This case report aims to reveal how a 76-year-old male patient with curves exceeding 110° is functioning with minimal difficulty. [Subject and Methods] The patient, who has never had surgical intervention for scoliosis, can perform his everyday activities...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28170387/early-growth-faltering-in-post-institutionalized-youth-and-later-anthropometric-and-pubertal-development
#18
Brie M Reid, Bradley S Miller, Lorah D Dorn, Christopher Desjardins, Bonny Donzella, Megan Gunnar
BACKGROUND: Early life adversity that increases the risk of growth stunting is hypothesized to increase the risk of obesity and, in girls, early onset puberty. This hypothesis was tested in children adopted from orphanages. METHODS: Post-institutionalized (PI) youth were compared with youth reared in comparable families (non-adopted; NA) on height, weight, pubertal stage, and fat mass (127 PI, 80 female; 156 NA, 85 female, aged 7-14 years). Anthropometrics at adoption were obtained from first US clinic visits...
February 7, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28164075/the-impact-of-obesity-on-hyperandrogenemia-in-korean-girls
#19
Min Jae Kang, Seung Yang, Il Tae Hwang
PURPOSE: As metabolic complication and polycystic ovarian syndrome due to childhood obesity is rising, the role of hyperandrogenemia (HA) and hyperinsulinism is receiving attention. The aims of this study were to investigate the presence of obvious HA according to pubertal status and to find potential etiologic determinants of HA in Korean obese (OB) girls. METHODS: We analyzed 91 girls aged 6-17 years (prepuberty, n=54; puberty, n=37). Each girl was classified as being either normal weight (NW) or OB...
December 2016: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/28164070/transgender-youth-current-concepts
#20
REVIEW
Stephen M Rosenthal
In many countries throughout the world, increasing numbers of gender nonconforming/transgender youth are seeking medical services to enable the development of physical characteristics consistent with their experienced gender. Such medical services include use of agents to block endogenous puberty at Tanner stage II with subsequent use of cross-sex hormones, and are based on longitudinal studies demonstrating that those individuals who were first identified as gender dysphoric in early or middle childhood and continue to meet the mental health criteria for being transgender at early puberty are likely to be transgender as adults...
December 2016: Annals of Pediatric Endocrinology & Metabolism
keyword
keyword
32698
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"