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central serous chorioretinopathy

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https://www.readbyqxmd.com/read/28076442/subfoveal-choroidal-thickness-in-central-serous-chorioretinopathy-a-meta-analysis
#1
Guohai Chen, Radouil Tzekov, Wensheng Li, Fangzheng Jiang, Sihong Mao, Yuhua Tong
PURPOSE: To evaluate the relationship between subfoveal choroidal thickness (SFCT) and eyes with central serous chorioretinopathy (CSC) versus fellow or control eyes. METHODS: We performed a meta-analysis using databases including PubMed, Embase and ISI Web of Science to find relevant studies. Weighted mean difference (WMD) was calculated for the SFCT in CSC eyes, the unaffected fellow eyes and normal controls. RESULTS: Twelve studies were selected for this meta-analysis, including 1108 eyes (397 CSC eyes, 228 unaffected fellow eyes and 483 eyes of normal controls)...
2017: PloS One
https://www.readbyqxmd.com/read/28067724/acute-central-serous-chorioretinopathy-factors-influencing-episode-duration
#2
Alejandra Daruich, Alexandre Matet, Laetitia Marchionno, Jean-Dominique De Azevedo, Aude Ambresin, Irmela Mantel, Francine Behar-Cohen
PURPOSE: To evaluate the influence of clinical and multimodal imaging parameters on the duration of acute central serous chorioretinopathy (CSCR) episodes. METHODS: Consecutive patients with first, treatment-naïve central serous chorioretinopathy episodes presenting within 20 days of symptoms onset were prospectively included. They were reevaluated 15 days to 20 days later, followed by monthly evaluation for 6 months. Subfoveal choroidal thickness (SFCT), fluorescein leakage intensity on fluorescein angiography, elevation of retinal pigment epithelium (RPE) lesions at leakage sites, focal/multifocal pattern of indocyanine green angiography (ICGA) at baseline, time-dependent pattern of subretinal fluid (SRF) resorption on OCT using volume segmentation, history of corticosteroid intake and mean blood pressure were evaluated using univariate (Log rank test) and multivariate (Cox proportional hazard regression) survival analysis...
January 6, 2017: Retina
https://www.readbyqxmd.com/read/28055101/high-resolution-imaging-of-intraretinal-structures-in-active-and-resolved-central-serous-chorioretinopathy
#3
Ryan N Vogel, Christopher S Langlo, Drew Scoles, Joseph Carroll, David V Weinberg, Judy E Kim
Purpose: We improved our understanding of central serous chorioretinopathy (CSC), we performed an analysis of noninvasive, high-resolution retinal imaging in patients with active and resolved CSC. Methods: Adaptive optics scanning light ophthalmoscopy (AOSLO) and spectral-domain optical coherence tomography (SD-OCT) were performed on five subjects with CSC. A custom AOSLO system was used to simultaneously collect confocal and split-detector images. Spectral domain-OCT volume scans were used to create en face views of various retinal layers, which then were compared to montaged AOSLO images after coregistration...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28053499/chronic-central-serous-chorioretinopathy-long-term-follow-up-and-vision-related-quality-of-life
#4
Myrte B Breukink, Alexander Jm Dingemans, Anneke I den Hollander, Jan Ee Keunen, Robert E MacLaren, Sascha Fauser, Giuseppe Querques, Carel B Hoyng, Susan M Downes, Camiel Jf Boon
PURPOSE: To describe the clinical findings and long-term outcome of patients with chronic central serous chorioretinopathy (cCSC). MATERIALS AND METHODS: This was a retrospective case series in 52 eyes of 36 patients with a follow-up period of at least 1 year. Extensive ophthalmic examination and a validated questionnaire concerning vision-related quality of life (National Eye Institute Visual Function Questionnaire [NEI-VFQ]-39) were analyzed. RESULTS: Mean visual acuity showed a significant decline over time of 0...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28050729/acute-lupus-choroidopathy-multimodal-imaging-and-differential-diagnosis-from-central-serous-chorioretinopathy
#5
Murat Hasanreisoglu, Gokcen D Gulpinar Ikiz, Hamit Kucuk, Ozkan Varan, Sengul Ozdek
IMPORTANCE: Systemic lupus erythematosus (SLE) is a thoroughly examined multi-organ disease whose common ocular complications are also well documented. However, SLE choroidopathy, being a rare ocular complication, is needed to be better understood, in order to make the differential diagnosis from clinical conditions such as central serous chorioretinopathy and provide adequate prompt treatment. OBJECTIVE: To provide a clear understanding for the clinical course of SLE choroidopathy by the help of enhanced depth imaging optical coherence tomography, fluorescein angiography, and indocyanine angiography...
January 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28050329/focal-choroidal-excavation
#6
Zafer Cebeci, Şerife Bayraktar, Merih Oray, Nur Kır
Focal choroidal excavation is a choroidal pit that can be detected by optical coherence tomography. Central serous chorioretinopathy, choroidal neovascularization and polypoidal choroidal vasculopathy are pathologies associated with focal choroidal excavation. In this article, we present the follow-up and treatment outcomes of three eyes of two patients with focal choroidal excavation.
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28018289/choroidal-and-retinal-abnormalities-by-optical-coherence-tomography-in-endogenous-cushing-s-syndrome
#7
Maria Fernanda Abalem, Marcio Carlos Machado, Helen Nazareth Veloso Dos Santos, Rafael Garcia, John Helal, Pedro Carlos Carricondo, Sérgio Luis Gianotti Pimentel, Mario Luiz Ribeiro Monteiro, Cynthia X Qian, Marcello Delano Bronstein, Maria Cândida Villares Barisson Fragoso
CONTEXT: Cortisol has been suggested as a risk factor for choroidal thickening, which may lead to retinal changes. OBJECTIVE: To compare choroidal thickness measurements using optical coherence tomography (OCT) in patients with endogenous active Cushing's syndrome (CS) and to evaluate the occurrence of retinal abnormalities in the same group of patients. DESIGN: Cross-sectional study. SETTING: Outpatient clinic. PATIENTS: Eleven female patients with CS in hypercortisolism state as determined by the presence of at least two abnormal measurements from urinary cortisol 24 h, no suppression of cortisol with low dose dexamethasone suppression test, and nocturnal salivary cortisol levels and 12 healthy controls...
2016: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28017901/central-serous-chorioretinopathy-following-medial-transposition-of-split-lateral-rectus-muscle-for-complete-oculomotor-nerve-palsy
#8
Rebecca Sorenson, Ajay Soni
No abstract text is available yet for this article.
December 22, 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28012104/intravitreal-dexamethasone-implant-for-the-treatment-of-cystoid-macular-oedema-associated-with-acute-retinal-necrosis
#9
Parthopratim Dutta Majumder, Jyotirmay Biswas, Asra Ambreen, Rowayda Amin, Zahedur Rahman Pannu, Ahmed Magdy Bedda
BACKGROUND: Acute retinal necrosis is a rare but devastating ocular condition. We report two cases of acute retinal necrosis in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant. RESULTS: Two patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular oedema following resolution of viral retinitis. Ocular condition of the first patient was further complicated by central serous chorioretinopathy...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28009402/choroidal-characteristics-of-acute-and-chronic-central-serous-chorioretinopathy-using-enhanced-depth-imaging-optical-coherence-tomography
#10
Jorge Ruiz-Medrano, Marco Pellegrini, Matteo G Cereda, Mario Cigada, Giovanni Staurenghi
PURPOSE: Central serous chorioretinopathy (CSC) is an idiopathic disorder characterized by serous detachments of the neurosensory retina and/or the retinal pigment epithelium affecting the macular area in the majority of cases. The objective of this study was to describe choroidal findings in patients with acute and chronic CSC based on enhanced depth imaging optical coherence tomography analysis. METHODS: This is a cross-sectional, noninterventional study performed at Luigi Sacco University Hospital of Milan...
November 18, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28000244/sensitivity-and-specificity-of-multispectral-imaging-in-detecting-central-serous-chorioretinopathy
#11
Xuemei Zhu, Yong Cheng, Xue Pan, Enzhong Jin, Shanshan Li, Mingwei Zhao, Xiaoxin Li
BACKGROUND AND OBJECTIVE: Central serous chorioretinopathy (CSCR) is a common and idiopathic retinal disorder that affects young to middle aged adults. The aim of this study was to describe the characteristics of eyes with CSCR using a light-emitting diode (LED)-based multispectral imaging (MSI) system and to evaluate the diagnostic reliability of MSI compared to fluorescein angiography (FA) in detecting CSCR. MATERIALS AND METHODS: A total of 56 eyes among 52 patients with 1 or more retinal pigment epithelium (RPE) abnormality were retrospectively enrolled in the study...
December 21, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27997459/short-term-findings-on-optical-coherence-tomography-and-microperimetry-in-chronic-central-serous-chorioretinopathy-patients-treated-with-half-dose-photodynamic-therapy
#12
Elon H C van Dijk, Greet Dijkman, Thomas Theelen, Carel B Hoyng, Camiel J F Boon
PURPOSE: To assess the short-term outcome of and possible temporary vision loss after half-dose verteporfin photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC). METHODS: In this prospective study, 14 eyes of 13 cCSC patients who underwent half-dose PDT were included. Patients received spectral-domain optical coherence tomography (OCT) imaging and microperimetry before PDT on the day of treatment and 1 week after treatment...
December 16, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27990593/is-the-unaffected-eye-really-unaffected-color-doppler-ultrasound-findings-in-unilaterally-active-central-serous-chorioretinopathy
#13
Iclal Erdem Toslak, Muhammet Kazim Erol, Devrim Toslak, Bulent Cekic, Mehtap Barc Ergun, Jennifer E Lim-Dunham
PURPOSE: To evaluate ocular hemodynamic changes using color Doppler ultrasonography imaging (CDI) with an emphasis on unaffected eyes of patients with central serous chorioretinopathy (CSC). METHODS: Twenty-seven patients with active CSC and 25 controls were analyzed using spectral domain-optical coherence tomography (SD-OCT) and CDI for choroidal imaging and evaluation of retrobulbar vessels, respectively. RESULTS: Resistive index (RI), pulsatility index (PI), and peak systolic velocity (PSV) of the ophthalmic artery (OA) and PSV, end-diastolic velocity (EDV), and mean velocity (Vmean) of the central retinal artery (CRA) in the patient group were less than those in the control group...
December 18, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27982209/subfoveal-choroidal-thickness-changes-after-intravitreal-bevacizumab-therapy-for-central-serous-chorioretinopathy
#14
Cihan Ünlü, Gurkan Erdogan, Tugba Aydogan Gezginaslan, Betul Ilkay Sezgin Akcay, Esra Kardes, Tahir Kansu Bozkurt
Purpose: To evaluate subfoveal choroidal thickness (SFCT) changes after intravitreal bevacizumab (IVB) therapy for central serous chorioretinopathy (CSC) using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Methods: In this retrospective study, we assessed the medical records of patients with CSC who received IVB (IVB group) or who were observed without intervention (control group). SFCT was measured using EDI-OCT. The main outcome measure was the change in SFCT...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27958201/evaluation-and-correlation-of-stress-scores-with-blood-pressure-endogenous-cortisol-levels-and-homocysteine-levels-in-patients-with-central-serous-chorioretinopathy-and-comparison-with-age-matched-controls
#15
Abhishek Agarwal, Monika Garg, Nikhil Dixit, Rohini Godara
CONTEXT: Stress had been associated with the development of central serous chorioretinopathy (CSC). The study was designed to evaluate the effect of stress on other risk factors of CSC such as serum cortisol levels, serum homocysteine levels, and blood pressure (BP) in CSC patients. AIMS: To compare stress scores, serum cortisol and serum homocysteine levels, and BP of CSC patients with that of control population and to correlate stress scores of CSC patients with BP, serum cortisol levels, and serum homocysteine levels...
November 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27941529/change-of-choroidal-volume-in-untreated-central-serous-chorioretinopathy
#16
Laura Pertl, Anton Haas, Silke Hausberger, Tamara Pichler, Dieter F Rabensteiner, Gerald Seidel, Eva M Malle, Martin Weger
PURPOSE: Choroidal hyperpermeability plays a central role in the pathophysiology of central serous chorioretinopathy (CSC). In active CSC undergoing treatment, choroidal thickness decreases if subretinal fluid (SRF) resolves. This study aimed to investigate the change in choroidal thickness and volume in eyes with untreated CSC. METHODS: The authors retrospectively analyzed 27 eyes with treatment-naïve CSC (25 patients), who had a follow-up of 4 to 6 weeks. Retinal and choroidal volume and SRF were segmented manually and calculated using the Spectralis OCT built-in software (Spectralis; Heidelberg Engineering)...
December 9, 2016: Retina
https://www.readbyqxmd.com/read/27929707/systemic-mineralocorticoid-antagonists-in-the-treatment-of-central-serous-chorioretinopathy
#17
Dong Yang, Dean Eliott
Central serous chorioretinopathy (CSCR) is a challenging disease characterized by subretinal serous fluid accumulation. The complex pathogenesis is still not fully understood, but is thought to be multifactorial and involves exogenous and endogenous factors affecting the choroid and retinal pigment epithelium. The involvement of corticosteroids is undisputed, while the contribution of mineralocorticoid pathways is under investigation. This review addresses the proposed pathogenesis models and the evidence for systemic treatment of CSCR with mineralocorticoid antagonists...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27905337/choroidal-thickness-evaluation-of-healthy-eyes-central-serous-chorioretinopathy-and-fellow-eyes-using-spectral-domain-optical-coherence-tomography-in-indian-population
#18
Supriya Arora, Richa Pyare, Preethi Sridharan, Tarun Arora, Meenakshi Thakar, Basudeb Ghosh
AIM: The purpose of this study is to establish a normative database of subfoveal choroidal thickness (CT) in healthy young Indians using spectral domain optical coherence tomography (SD OCT). Evaluation and comparison of CT of central serous chorioretinopathy (CSC) and fellow eyes were also performed. MATERIALS AND METHODS: This was a prospective, cross-sectional, and observational study. It included 112 normal eyes of 112 healthy volunteers who had no evidence of ocular or systemic disease, 84 CSC eyes with acute, treatment-naïve CSC, and 69 fellow eyes with no evidence of neurosensory detachment or pigment epithelium detachment on SD OCT...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27902539/cystoid-macular-edema-and-cystoid-macular-degeneration-as-a-result-of-multiple-pathogenic-factors-in-the-setting-of-central-serous-chorioretinopathy
#19
Polina Astroz, Chandrakumar Balaratnasingam, Lawrence A Yannuzzi
PURPOSE: To report the pathogenic factors that account for cystoid macular edema and cystoid macular degeneration in chronic central serous chorioretinopathy (CSC). METHODS: The clinical course and multimodal imaging findings, including fundus color photography, fundus autofluorescence, spectral-domain optical coherence tomography, and fluorescein angiography, of one eye with cystoid macular edema due to chronic CSC was documented. RESULTS: A 44-year old woman with a history of chronic CSC presented with progressive visual decline in the right eye...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27882013/effect-of-half-adult-dose-of-oral-rifampicin-300mg-in-patients-with-idiopathic-central-serous-chorioretinopathy
#20
Muhammad Saim Khan, Murtaza Sameen, Arshad Ali Lodhi, Munawar Ahmed, Noman Ahmed, Mustafa Kamal, Sameen Afzal Junejo
OBJECTIVES: To evaluate the effect of half adult dose of oral Rifampicin on mean change in best corrected visual acuity and central macular thickness in patients with central serous chorioretinopathy. METHODS: Thirty-eight eyes of 31 patients with idiopathic central serous chorioretinopathy (CSCR) were registered. Unaided Visual acuity, best corrected visual acuity was documented and detailed slit lamp examination along with dilated ophthalmoscopy was performed...
September 2016: Pakistan Journal of Medical Sciences Quarterly
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