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https://www.readbyqxmd.com/read/29148590/effects-of-bergenin-on-methylglyoxal-induced-damage-in-osteoblastic-mc3t3-e1-cells
#1
Kyung Hee Lee, Eun Mi Choi
Bergenin is the main chemical constituent of plants in the genus Bergenia, which are used in traditional medicines. Methylglyoxal (MG), a highly reactive dicarbonyl compound, is the major precursor for forming advanced glycation end products (AGEs). Pretreating MC3T3-E1 cells with bergenin prevented MG-induced protein adduct formation. Bergenin inhibited the MG-induced soluble receptor for AGE (sRAGE), interleukin, reactive oxygen species and mitochondrial superoxide production. Additionally bergenin increased glyoxalase I activity, glutathione, heme oxygenase-1 and nuclear factor erythroid 2-related factor 2 levels in the presence of MG...
November 17, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/29144803/endocrine-manifestations-of-primary-hyperoxaluria
#2
Shatha Murad, Yuval Eisenberg
OBJECTIVE: Primary hyperoxaluria type 1 (PH1) is a rare metabolic disorder of oxalate overproduction. It is associated with urolithiasis and nephrocalcinosis which progress to ESRD and systemic oxalosis. As oxalate deposits in tissues, non-parathyroid hormone (nonPTH) mediated hypercalcemia, oxalate osteopathy, primary hypothyroidism and primary hypogonadism develop. In this review, we will present a case of PH1 and provide an overview of this clinical entity and its endocrine manifestations...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29137632/descriptive-study-of-interprofessional-collaboration-between-physicians-and-osteopaths-for-the-pediatric-population-in-quebec-canada
#3
Chantal Morin, Johanne Desrosiers, Isabelle Gaboury
BACKGROUND: Osteopathy is an increasingly popular healthcare approach that uses a wide variety of therapeutic manual techniques to address pain and somatic dysfunction. In Quebec, Canada, osteopathy is the complementary medicine most often recommended by family physicians. However, factors fostering the development of interprofessional collaboration (IPC) between physicians and osteopaths are unknown. This study aimed to describe the current situation in terms of IPC among practitioners working with pediatric patients...
November 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29122261/evaluation-of-new-zealand-osteopathy-patients-experiences-of-their-treatment
#4
Rochelle Judkins, Brett Vaughan, Jane Mulcahy
OBJECTIVES: To investigate the experiences of patients seeking osteopathy treatment in New Zealand; and to describe their perceptions of osteopathic treatment. DESIGN: Survey-based research design. SETTING: Private osteopathy practices. MAIN OUTCOME MEASURES: Demographic survey and the Patient Perception Measure-Osteopathy (PPM-O). RESULTS: Twelve osteopaths were recruited as practitioners. Responses from 107 patients were analysed...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29101775/outpatient-satisfaction-with-osteopathic-manipulative-treatment-in-a-hospital-center-a-survey
#5
Marco Tramontano, Alex Martino Cinnera, Marco Petracca, Angela Gaeta, Federica Tamburella, Maurice Audouard, Carlo Caltagirone
Context • Although osteopathy is not yet certified as a health profession in Italy, many people choose osteopathic manipulative treatment (OMT) for pain relief. Nevertheless, no study evaluating patients' degree of satisfaction after OMT and the perceived quality of the treatment has occurred in Italy. Objectives • The study intended to assess outpatients' satisfaction with OMT carried out at a hospital. Design • The research team conducted a survey from January 2015 to January 2016 using 3 questionnaires...
October 28, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29080893/osteopathie-bei-gastro%C3%A3-sophagealem-reflux-mit-hiatushernie-ein-fallbericht-gem%C3%A3-%C3%A3-der-care-leitlinie
#6
Gabriele Rotter, Benno Brinkhaus
No abstract text is available yet for this article.
October 27, 2017: Complementary Medicine Research
https://www.readbyqxmd.com/read/29067209/complementary-and-alternative-medicine-for-the-management-of-orthopaedic-problems-in-swiss-warmblood-horses
#7
Catharina D Lange, Shannon Axiak Flammer, Vinzenz Gerber, Ditte Kindt, Christoph Koch
It appears that complementary and alternative medicine (CAM) is used increasingly often in horses for the assessment and treatment of suspected orthopaedic problems, especially back problems. The aim of this study was to determine the frequency of CAM use for the management of orthopaedic problems in a defined population of Swiss Warmblood horses. A total of 239 owners and caretakers of horses from a pre-defined database were called by a veterinarian to participate in the survey. A standardized questionnaire was designed to determine, for each orthopaedic case, where the localization of the problem was (limb or back) and if conventional medicine or CAM was used for consultation and treatment...
August 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/28987037/hypnosis-and-osteopathic-manipulative-treatment-for-visual-disorders-during-pregnancy-a-case-report
#8
Giancarlo Russo, Alessandro Remonato, Roberto Remonato, Emiliano Zanier
Context • Pregnancy causes physiological alterations to the visual system, particularly in relation to retinal vascularization, with a consequent increase of intraocular pressure, and to the lacrimal fluid, with a consequent ocular dryness, which both can lead to a reduction in visual acuity. Numerous case reports refer to the employment of hypnotic treatment in cases of myopia, but the literature does not report any case of decreased visual acuity postpartum that was treated with hypnosis. Objective • For women with visual disorders that had appeared during pregnancy or were preexisting, the study intended to evaluate the benefits of treatment of the diaphragm by hypnotherapy and osteopathy to modify intracorporeal pressure and restore the women's visual function...
July 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28986142/limonene-protects-osteoblasts-against-methylglyoxal-derived-adduct-formation-by-regulating-glyoxalase-oxidative-stress-and-mitochondrial-function
#9
Kwang Sik Suh, Suk Chon, Eun Mi Choi
Methylglyoxal (MG) is a potent protein glycating agent and an important precursor of advanced glycation end products, which are involved in the pathogenesis of diabetic osteopathy. In this study, we investigated the effects of limonene on MG-induced damage in osteoblastic MC3T3-E1 cells. Pretreating cells with limonene prevented MG-induced protein adduct formation, tumor necrosis factor alpha and interleukin-6 release, mitochondrial superoxide production, and cardiolipin peroxidation. In addition, limonene increased glyoxalase I activity, and glutathione and heme oxygenase-1 levels in the presence of MG...
October 3, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28967496/age-related-changes-in-biochemical-bone-profile-in-thalassemic-children
#10
Ehab S Abd El-Moneim, Mohammed A Zolaly, Zakaria M Al-Hawsawi, Abeer A Abdelmoneim, Mostafa M Abosdera
BACKGROUND: Osteopathy is an important cause of morbidity in β-thalassemia major (TM). Although many of the etiopathological factors implicated in thalassemic osteoporosis commence in early disease phases during childhood, limited information exists on bone turnover in children with TM. This study was conducted with the objective to compare bone turnover markers (BTMs) in thalassemic children at different ages. METHODS: In a cross sectional case control study, 47 children (age range, 1...
August 26, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28940654/video-assisted-microwave-ablation-for-the-treatment-of-a-metastatic-lung-lesion-in-a-dog-with-appendicular-osteosarcoma-and-hypertrophic-osteopathy
#11
Kaitlyn Mazzaccari, Sarah E Boston, Beau B Toskich, Kristina Bowles, J Brad Case
OBJECTIVE: To describe video-assisted microwave ablation (VAMA) for the treatment of a metastatic lung lesion secondary to right forelimb osteosarcoma in a dog. STUDY DESIGN: Case report. ANIMALS: A 10-year-old female spayed mixed breed dog with a metastatic lung lesion secondary to appendicular osteosarcoma. METHODS: An osteosarcoma of the right distal scapula and proximal humerus that was suspected to be a radiation-induced osteosarcoma was treated with limb amputation and carboplatin chemotherapy...
September 22, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28940469/cytoprotective-effects-of-xanthohumol-against-methylglyoxal-induced-cytotoxicity-in-mc3t3-e1-osteoblastic-cells
#12
Kwang Sik Suh, Suk Chon, Eun Mi Choi
Methylglyoxal (MG) has been suggested to be a major source of intracellular reactive carbonyl compounds, and has been implicated in increasing the levels of advanced glycation end products in age-related diseases. Xanthohumol is a prenylated flavonoid found in hops (Humulus lupulus) and beer. In the present study, we investigated the effects of xanthohumol on MG-induced cytotoxicity in osteoblastic MC3T3-E1 cells. Xanthohumol attenuated MG-induced cytotoxicity, as evidenced by improved cell viability, and prevented MG-induced MG-protein adducts, inflammatory cytokines, reactive oxygen species and mitochondrial superoxide production...
September 20, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28937024/celiac-disease-related-osteopathy-among-saudi-celiac-patients-are-we-adherent-to-recommendations
#13
Mona A Fouda
BACKGROUND/AIMS: There are no reports from Saudi Arabia documenting the picture of osteopathy in celiac disease (CD) and the adherence of physicians to the guidelines and recommendations to screen for bone disease. We conducted this study to document the prevalence of CD-related osteopathy and the Saudi physicians' adherence to the screening recommendations. PATIENTS AND METHODS: We identified the biopsy proven CD cases diagnosed between 2003 and 2012. In addition to demographic data, we collected laboratory (serum calcium, phosphate, alkaline phosphatase, 25-dihydroxy vitamin D, and parathyroid hormone levels) and imaging [Dual-energy X-ray absorptiometry (DEXA)] data...
September 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28870281/workplace-injuries-in-the-australian-allied-health-workforce
#14
Sarah Anderson, Rwth Stuckey, Lauren V Fortington, Jodi Oakman
Objective This study aims to identify the number, costs and reported injury mechanisms of serious injury claims for allied health professionals.Methods Using Australian Workers' Compensation injury data, the number, mechanism, and costs of injury claims were calculated for eight groups of allied health professions (chiropractors and osteopaths, speech pathologists and audiologists, occupational therapists, physiotherapists, psychologists, podiatrists, social workers and prosthetists/orthotists) between the 2000-01 and 2013-14 financial years...
September 5, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28792794/squamous-cell-carcinoma-of-the-penis-with-pulmonary-metastasis-and-paraneoplastic-hypertrophic-osteopathy-in-a-dog
#15
Victoria Jenkins, Carlos Henrique de Mello Souza, Louis-Phillippe de Lorimier, Evandro de Toledo-Piza
Squamous cell carcinoma of the penis was diagnosed by incisional biopsy of a penile mass in a 12 yr old intact male beagle dog presenting with hemorrhagic discharge from the prepuce. Penile amputation, orchiectomy with scrotal ablation, and scrotal urethrostomy were performed. Hypertrophic osteopathy secondary to pulmonary metastatic disease occurred 10 mo after the surgery. Palliative treatment with piroxicam was administered and led to complete resolution of the clinical signs of the pain. Sixteen months following surgery, the dog presented with significant dyspnea and anorexia and was euthanized due to poor prognosis...
September 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28735822/conservative-management-of-a-traumatic-meniscal-injury-utilising-osteopathy-and-exercise-rehabilitation-a-case-report
#16
Jack Feehan, Chris Macfarlane, Brett Vaughan
Meniscal injury is one of the most common knee soft tissue injuries, commonly affecting young athletes and an older, degenerative population. Treatment largely depends on the type and extent of the injury with arthroscopic repair or meniscectomy being mainstays. Although non-surgical approaches have been described, there is no published literature regarding a combination of indirect osteopathic techniques and rehabilitation in the management of these injuries. The current case report follows a 20-year-old male presenting with a 5-day history of acute knee pain, following trauma during an Australian Rules Football (AFL) match...
August 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28718587/-drugs-induced-osteopathies
#17
Bérengère Aubry-Rozier
Drug induced bone diseases concerns : induced osteoporosis, induced osteomalacia (by loss of calcium, phosphate or vitamin D) and induced sarcopenia. Some of these drugs are well known, such as anti-hormones, corticotherapy (which could induce all of osteoporosis, osteomalacia and sarcopenia). In the present article, we will focus on 3 others less known but frequently used drugs : iron replacement, proton pump inhibitors therapy, and serotonin reuptake inhibitor antidepressants treatment. For each of them we will discuss the pathophysiological mechanism leading to bone fragility as well as the recommendations of prevention / management to be proposed in case of absolute necessity of the treatment...
March 8, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28690741/-osteopecilia-associated-with-psoriatic-arthritis
#18
Zeineb Alaya, Walid Osman, Laassad Hassini, Houneida Zaghouani, Nader Naouar, Elyès Bouajina
Osteopecilia is a benign and rare condensing osteopathy. Its association with inflammatory rheumatism is very rare. We here report the case of a 25-year old patient with skin psoriasis, presenting with groin pain of inflammatory origin. Physical examination showed limitation of hip motions, lower limb-length inequality and pain on right sacroiliac mobilization. Laboratory tests showed inflammatory syndrome and negative immunological assessment. The radiograph of the pelvis revealed osteopecilia associated with destructive coxitis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28689272/insulin-does-not-rescue-cortical-and-trabecular-bone-loss-in-type-2-diabetic-goto-kakizaki-rats
#19
Ratchaneevan Aeimlapa, Narattaphol Charoenphandhu, Panan Suntornsaratoon, Kannikar Wongdee, Wacharaporn Tiyasatkulkovit, Kanchana Kengkoom, Nateetip Krishnamra
In type 2 diabetes mellitus (T2DM), the decreased bone strength is often associated with hyperglycemia and bone cell insulin resistance. Since T2DM is increasingly reported in young adults, it is not known whether the effect of T2DM on bone would be different in young adolescents and aging adults. Here, we found shorter femoral and tibial lengths in 7-month, but not 13-month, Goto-Kakizaki (GK) T2DM rats as compared to wild-type rats. Bone µCT analysis showed long-lasting impairment of both cortical and trabecular bones in GK rats...
July 8, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28643968/-complementary-medicine-for-low-back-pain-what-is-the-scientific-evidence
#20
Éléonore Aveni, Chantal Berna, Pierre-Yves Rodondi
Complementary medicines are frequently used by chronic pain patients. It is a challenge for the primary care physician to provide objective information based on the scientific literature. Meta-analyses have shown favourable effects of acupuncture, therapeutic massage and osteopathy for patients with acute low back pain. Concerning chronic low back pain, meta-analyses have shown positive results with acupuncture, osteopathy, yoga and tai-chi. Other therapies have shown positive effects, but further trials are necessary to fully validate them...
June 21, 2017: Revue Médicale Suisse
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