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https://www.readbyqxmd.com/read/28334396/quantifying-circular-rna-expression-from-rna-seq-data-using-model-based-framework
#1
Musheng Li, Xueying Xie, Jing Zhou, Mengying Sheng, Xiaofeng Yin, Eun-A Ko, Tong Zhou, Wanjun Gu
Motivation: Circular RNAs (circRNAs) are a class of non-coding RNAs that are widely expressed in various cell lines and tissues of many organisms. Although the exact function of many circRNAs is largely unknown, the cell type- and tissue-specific circRNA expression has implicated their crucial functions in many biological processes. Hence, the quantification of circRNA expression from high-throughput RNA-seq data is becoming important to ascertain. Although many model-based methods have been developed to quantify linear RNA expression from RNA-seq data, these methods are not applicable to circRNA quantification...
March 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28316116/water-availability-drives-signatures-of-local-adaptation-in-whitebark-pine-pinus-albicaulis-englm-across-fine-spatial-scales-of-the-lake-tahoe-basin-usa
#2
Brandon M Lind, Christopher J Friedline, Jill L Wegrzyn, Patricia E Maloney, Detlev R Vogler, David B Neale, Andrew J Eckert
Patterns of local adaptation at fine spatial scales are central to understanding how evolution proceeds, and are essential to the effective management of economically and ecologically important forest tree species. Here, we employ single and multilocus analyses of genetic data (n = 116,231 SNPs) to describe signatures of fine-scale adaptation within eight whitebark pine (Pinus albicaulis Engelm.) populations across the local extent of the environmentally heterogeneous Lake Tahoe Basin, USA. We show that despite highly shared genetic variation (FST = 0...
March 17, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28263664/abstracts-of-the-2017-aans-cns-joint-section-on-disorders-of-the-spine-and-peripheral-nerves-las-vegas-nevada-%C3%A2-march-8-11-2017
#3
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28262572/evaluation-of-multiple-tracer-methods-to-estimate-low-groundwater-flow-velocities
#4
Paul W Reimus, Bill W Arnold
Four different tracer methods were used to estimate groundwater flow velocity at a multiple-well site in the saturated alluvium south of Yucca Mountain, Nevada: (1) two single-well tracer tests with different rest or "shut-in" periods, (2) a cross-hole tracer test with an extended flow interruption, (3) a comparison of two tracer decay curves in an injection borehole with and without pumping of a downgradient well, and (4) a natural-gradient tracer test. Such tracer methods are potentially very useful for estimating groundwater velocities when hydraulic gradients are flat (and hence uncertain) and also when water level and hydraulic conductivity data are sparse, both of which were the case at this test location...
February 20, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28257715/an-assessment-of-diarrhea-among-long-distance-backpackers-in-the-sierra-nevada
#5
Derek J Meyer, Amber Costantino, Susanne Spano
INTRODUCTION: Diarrhea is a common problem among long-distance backpackers, ranging in overall incidence from 11-56% as reported by previous studies on the Appalachian Trail and Long Trail. Differences in age, sex, and regularity of standard backcountry hygiene recommendations and practices have been shown to significantly affect the incidence of diarrhea. No study to date has investigated these trends among long-distance backpackers on the John Muir Trail (JMT) in the Sierra Nevada mountain range of California...
March 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28256327/st-segment-elevation-myocardial-infarction-systems-of-care-an-urgent-need-for-policies-to-co-ordinate-care-in-order-to-decrease-in-hospital-mortality
#6
Ali Osama Malik, Oliver Abela, Gayle Allenback, Subodh Devabhaktuni, Calvin Lui, Aditi Singh, Jimmy Diep, Takashi Yamashita, Ji Won Yoo, Sanjay Malhotra, Chowdhury Ahsan
BACKGROUND: Regional trends for ST-segment elevation myocardial infarction (STEMI) treatment is not known in the state of Nevada. HYPOTHESIS: Great disparity exists for treatment for STEMI in different geographical areas of Nevada. There is a great potential to improve treatment and outcomes of STEMI patients in the State of Nevada. METHODS: Admissions to non-federal hospitals in the state of Nevada, using 2011 to 2013 discharge data from the Nevada State Inpatient Data Base (acquired from Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality), were analyzed...
February 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28255333/impact-of-data-model-and-point-density-on-aboveground-forest-biomass-estimation-from-airborne-lidar
#7
Mariano Garcia, Sassan Saatchi, Antonio Ferraz, Carlos Alberto Silva, Susan Ustin, Alexander Koltunov, Heiko Balzter
BACKGROUND: Accurate estimation of aboveground forest biomass (AGB) and its dynamics is of paramount importance in understanding the role of forest in the carbon cycle and the effective implementation of climate change mitigation policies. LiDAR is currently the most accurate technology for AGB estimation. LiDAR metrics can be derived from the 3D point cloud (echo-based) or from the canopy height model (CHM). Different sensors and survey configurations can affect the metrics derived from the LiDAR data...
December 2017: Carbon Balance and Management
https://www.readbyqxmd.com/read/28251299/variations-in-chemical-sexual-signals-of-psammodromus-algirus-lizards-along-an-elevation-gradient-may-reflect-altitudinal-variation-in-microclimatic-conditions
#8
José Martín, Francisco Javier Zamora-Camacho, Senda Reguera, Pilar López, Gregorio Moreno-Rueda
Chemical signals used in intraspecific communication are expected to evolve or to show phenotipic plasticity to maximize efficacy in the climatic conditions of a given environment. Elevational environmental gradients in mountains provide a good opportunity to test this hypothesis by examining variation in characteristics of signals in species found across different elevations with different climatic conditions. We analyzed by gas chromatography-mass spectrometry (GC-MS) the lipophilic fraction of the femoral gland secretions of male lizards Psammodromus algirus (Fam...
April 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28222091/perceived-benefits-and-barriers-of-cervical-cancer-screening-among-chinese-american-women
#9
Wei-Chen Tung, Minggen Lu, Michelle Granner
PURPOSE/OBJECTIVES: To explore the perceived benefits and barriers to cervical cancer screening among Chinese American women using stages of the Transtheoretical Model of Change.
. DESIGN: Cross-sectional design with self-report surveys. 
. SETTING: Chinese communities (e.g., churches, supermarkets, restaurants) in Northern California and Northern Nevada. 
. SAMPLE: 121 Chinese women aged 21-65 years living in Northern California and Northern Nevada...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28213544/isolation-and-characterization-of-a-unique-strain-of-rickettsia-parkeri-associated-with-the-hard-tick-dermacentor-parumapertus-neumann-in-the-western-united-states
#10
Christopher D Paddock, Michelle E J Allerdice, Sandor E Karpathy, William L Nicholson, Michael L Levin, Travis C Smith, Tom Becker, Robert J Delph, Robert N Knight, Jana M Ritter, Jeanine H Sanders, Jerome Goddard
In 1953, investigators at the Rocky Mountain Laboratories in Hamilton, Montana, described the isolation of a spotted fever group Rickettsia (SFGR) species from Dermacentor parumapertus collected from black-tailed jackrabbits (Lepus californicus) in northern Nevada. Several decades later, investigators characterized this SFGR by using mouse serotyping methods and determined that it represented a distinct rickettsial serotype, related closely to Rickettsia parkeri; nonetheless, the parumapertus agent was not further characterized or studied...
February 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28208641/temporal-trends-in-satellite-derived-erythemal-uvb-and-implications-for-ambient-sun-exposure-assessment
#11
Marvin Langston, Leslie Dennis, Charles Lynch, Denise Roe, Heidi Brown
Ultraviolet radiation (UVR) has been associated with various health outcomes, including skin cancers, vitamin D insufficiency, and multiple sclerosis. Measurement of UVR has been difficult, traditionally relying on subject recall. We investigated trends in satellite-derived UVB from 1978 to 2014 within the continental United States (US) to inform UVR exposure assessment and determine the potential magnitude of misclassification bias created by ignoring these trends. Monthly UVB data remotely sensed from various NASA satellites were used to investigate changes over time in the United States using linear regression with a harmonic function...
February 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28182978/modeling-background-radiation-in-southern-nevada
#12
Daniel A Haber, Pamela C Burnley, Christopher T Adcock, Russell L Malchow, Kara E Marsac, Elisabeth M Hausrath
Aerial gamma ray surveys are an important tool for national security, scientific, and industrial interests in determining locations of both anthropogenic and natural sources of radioactivity. There is a relationship between radioactivity and geology and in the past this relationship has been used to predict geology from an aerial survey. The purpose of this project is to develop a method to predict the radiologic exposure rate of the geologic materials by creating a high resolution background model. The intention is for this method to be used in an emergency response scenario where the background radiation environment is unknown...
February 6, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28159490/chemohormonal-therapy-in-metastatic-hormone-sensitive-prostate-cancer-sweeney-cj-chen-yh-carducci-m-liu-g-jarrard-df-eisenberger-m-wong-yn-hahn-n-kohli-m-cooney-mm-dreicer-r-vogelzang-nj-picus-j-shevrin-d-hussain-m-garcia-ja-dipaola-rs-department-of-medicine
#13
Eggener Scott
BACKGROUND: Androgen deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with ADT plus docetaxel would result in longer overall survival than that with ADT alone. METHODS: We assigned men with metastatic, hormone-sensitive prostate cancer to receive either ADT plus docetaxel (at a dose of 75mg per square meter of body-surface area every 3wk for 6 cycles) or ADT alone...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28152736/cancer-depression-and-health-care-coverage-in-the-state-of-nevada-a-retrospective-cross-sectional-study
#14
Manas Agastya, Yaser Dawod, Linha Phan, Mohammad Talha Farooqui, Ji Won Yoo
42 Background: The prevalence of depressive disorders in patients with malignancies is estimated at 20-50%, significantly greater than the general population. Existing literature reports a negative impact of depression on both the patient and their families. There is limited information regarding the impact of healthcare coverage on the prevalence of depression in such patients both in the state of Nevada and nationwide. METHODS: A retrospective cross-sectional study was performed using the Behavioral Risk Surveillance System (BRFSS) database from 2010 to 2014...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150176/health-hazards-in-the-home-an-assessment-of-a-southern-nevada-community
#15
Amanda Sokolowsky, Erika Marquez, Erin Sheehy, Casey Barber, Shawn Gerstenberger
As a sub-grantee of a Department of Housing and Urban Development (HUD) Lead Hazard Control and Healthy Homes Program, the University of Nevada, Las Vegas' Department of Environmental and Occupational Health performed lead and Healthy Homes investigations and collected data regarding conditions in the home environment in Henderson, Nevada. The purpose of this research is to characterize housing conditions in southern Nevada, compare data to census data, and to highlight the health outcomes associated with adverse housing conditions...
February 1, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28135293/molecular-analyses-reveal-unexpected-genetic-structure-in-iberian-ibex-populations
#16
Samer Angelone-Alasaad, Iris Biebach, Jesús M Pérez, Ramón C Soriguer, José E Granados
BACKGROUND: Genetic differentiation in historically connected populations could be the result of genetic drift or adaptation, two processes that imply a need for differing strategies in population management. The aim of our study was to use neutral genetic markers to characterize C. pyrenaica populations genetically and examine results in terms of (i) demographic history, (ii) subspecific classification and (iii) the implications for the management of Iberian ibex. METHODOLOGY/PRINCIPAL FINDINGS: We used 30 neutral microsatellite markers from 333 Iberian ibex to explore genetic diversity in the three main Iberian ibex populations in Spain corresponding to the two persisting subspecies (victoria and hispanica)...
2017: PloS One
https://www.readbyqxmd.com/read/28125576/invasive-cancer-incidence-and-survival-united-states-2013
#17
S Jane Henley, Simple D Singh, Jessica King, Reda J Wilson, Mary Elizabeth O'Neil, A Blythe Ryerson
Although cancer represents many heterogeneous diseases, some cancer types share common risk factors. For example, conclusive evidence links cancer at multiple sites with tobacco use, alcohol use, human papillomavirus (HPV) infection, excess body weight, and physical inactivity (1,2). To monitor changes in cancer incidence and assess progress toward achieving Healthy People 2020 objectives,* CDC analyzed data from the U.S. Cancer Statistics (USCS) data set for 2013, the most recent year for which incidence and survival data are available...
January 27, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28124092/a-word-to-the-wise-advice-for-scientists-engaged-in-collaborative-adaptive-management
#18
Peter Hopkinson, Ann Huber, David S Saah, John J Battles
Collaborative adaptive management is a process for making decisions about the environment in the face of uncertainty and conflict. Scientists have a central role to play in these decisions. However, while scientists are well trained to reduce uncertainty by discovering new knowledge, most lack experience with the means to mitigate conflict in contested situations. To address this gap, we drew from our efforts coordinating a large collaborative adaptive management effort, the Sierra Nevada Adaptive Management Project, to offer advice to our fellow environmental scientists...
January 25, 2017: Environmental Management
https://www.readbyqxmd.com/read/28114852/cyanide-poisoning-of-a-cooper-s-hawk-accipiter-cooperii
#19
J Christian Franson
A Cooper's hawk ( Accipiter cooperii) was found dead in a ditch leading from a heap leach pad at a gold mine in Nevada. Observations at autopsy included an absence of external lesions, traces of subcutaneous and coronary fat, no food in the upper gastrointestinal tract, and no lesions in the viscera. Cyanide concentrations (µg/g ww) were 5.04 in blood, 3.88 in liver, and 1.79 in brain. No bacteria or viruses were isolated from tissues, and brain cholinesterase activity was within the normal range for a Cooper's hawk...
January 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28102652/changing-rural-and-urban-enrollment-in-state-medicaid-programs
#20
Abigail R Barker, Kelsey Huntzberry, Timothy D McBride, Keith J Mueller
Purpose. From October 2013—before implementation of the Affordable Care Act (ACA)—to November 2016, Medicaid enrollment grew by 27 percent. However, very little attention has been paid to date to how changes in Medicaid enrollment vary within states across the rural-urban continuum. This brief reports and analyzes changes in enrollment in metropolitan, micropolitan, and rural (noncore) areas in both expansion states (those that used ACA funding to expand Medicaid coverage) and nonexpansion states (those that did not use ACA funding to expand Medicaid coverage)...
January 2017: Rural Policy Brief
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