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https://www.readbyqxmd.com/read/28727097/evaluating-the-impact-of-breed-pregnancy-and-hair-coat-on-body-temperature-and-sweating-rate-of-hair-sheep-ewes-in-the-tropics
#1
R W Godfrey, W D Preston, S R Joseph, L LaPlace, P E Hillman, K G Gebremedhin, C N Lee, R J Collier
The objective of this study was to evaluate the effect of pregnancy, breed, and hair coat on body temperature and sweating rate (SR) of hair sheep. St. Croix White (STX; = 9) and Dorper × STX (DRPX; = 9) ewes (3.6 yr of age) were evaluated over 4 d at 126 d of gestation (PREG) and over 4 d at 46 d postpartum (OPEN) in the shade and sun and in the morning (AM; 0900 to 1200 h) and afternoon (PM; 1300 to 1600 h) after a 20 min acclimation to each condition on each day. Data loggers recorded vaginal temperature (VT) at 10-min intervals for 96 h...
July 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28723140/rapid-and-label-free-detection-of-interferon-gamma-via-an-electrochemical-aptasensor-comprising-a-ternary-surface-monolayer-on-a-gold-interdigitated-electrode-array
#2
Shaowei Ding, Curtis Mosher, Xian Y Lee, Suprem R Das, Allison A Cargill, Xiaohui Tang, Bolin Chen, Eric S McLamore, Carmen Gomes, Jesse M Hostetter, Jonathan C Claussen
A label-free electrochemical impedance spectroscopy (EIS) aptasensor for rapid detection (<35 min) of interferon-gamma (IFN-γ) was fabricated by immobilizing a RNA aptamer capture probe (ACP), selective to IFN-γ, on a gold interdigitated electrode array (Au IDE). The ACP was modified with a thiol group at the 5' terminal end and subsequently co-immobilized with 1,6-hexanedithiol (HDT) and 6-mercapto-1-hexanolphosphate (MCH) to the gold surface through thiol-gold interactions. This ACP/HDT-MCH ternary surface monolayer facilitates efficient hybridization with IFN-γ and displays high resistance to nonspecific adsorption of nontarget proteins [i...
February 24, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28721628/disease-activity-handgrip-strengths-and-hand-dexterity-in-patients-with-rheumatoid-arthritis
#3
D Palamar, G Er, R Terlemez, I Ustun, G Can, M Saridogan
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the hand joints and leading to impairment in hand functions. Evaluation of functional impairment is necessary for assessing patient's quality of life, disease activity, and treatment outcome. To date, many scientific studies assessed the disease activity of patients with RA, but little attention has been carried out to assess these patients' hand functions and dexterity. The purposes of this study were to determine the clinical relevance of the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH), hand dexterity with the Purdue Pegboard Test (PPT), and handgrip strength and pinch strengths of RA patients and to look into their relation between each other...
July 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28720220/application-of-ultrahigh-performance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-for-the-characterization-of-organic-aerosol-searching-for-naphthenic-acids
#4
Mahmoud M Yassine, Ewa Dabek-Zlotorzynska
Naphthenic acids (NAs) are naturally occurring constituents of hydrocarbon deposits (petroleum, oil sands bitumen, and crude oils), and present in any facilities that extract, process or use crude oil or bitumen for manufacturing. In the Athabasca oil sands region (AOSR) of Alberta, Canada, this diverse group of saturated acyclic, monocyclic, and polycyclic carboxylic acids is present in bitumen and in tailing ponds. Little is known about the occurrence of residual oil sands derived organic material, including NAs, in atmospheric particulate matter (PM)...
June 28, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28719088/understanding-and-managing-the-risk-of-head-impact-from-in-hospital-falls-a-cross-sectional-analysis-of-data-from-166-public-hospitals
#5
Satyan R Chari, Paul Varghese, Rebecca A R Bell, Kate Smith, Terry P Haines
BACKGROUND: Falls are a leading cause of preventable harm in the hospitalized elderly, and head impacts (HIs) can be a precursor to serious injury. The aim of this study was to examine if the risk of fall-related HI can be explained by incident characteristics. METHODS: All reported falls across public hospital facilities in the state of Queensland, Australia, over a 2-year period were analyzed using univariate and multiple logistic regression. RESULTS: In all, 650 instances of HI were reported across 24 218 falls...
July 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28717850/physio-biochemical-parameters-a-potential-tool-for-target-selective-treatment-of-haemonchosis-in-the-small-ruminants
#6
Bhupamani Das, Niranjan Kumar, Mehul M Jadav, Jayesh B Solanki, T K S Rao
This study aims to evaluate the conjunctiva colour-based FAMACHA score (FS) coupled with a body condition score (BCS), haemogram and stressor hormone level estimation, in identifying post-mortem (PM)/coproscopically proven individuals wanting therapy for economically important gastrointestinal (GI) helminths, Haemonchus contortus, in the small ruminants. The incidence of haemonchosis was significantly (p < 0.05) higher (60.81%) in the ruminants with FS = 3. The H. contortus count in the animals with FS 2, 3 and 4 was 23...
July 17, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28717513/unexpected-intensive-care-transfer-of-admitted-patients-with-severe-sepsis
#7
Gabriel Wardi, Arvin R Wali, Julian Villar, Vaishal Tolia, Christian Tomaszewski, Christian Sloane, Peter Fedullo, Jeremy R Beitler, Matthew Nolan, Daniel Lasoff, Rebecca E Sell
BACKGROUND: Patients with severe sepsis generally respond well to initial therapy administered in the emergency department (ED), but a subset later decompensate and require unexpected transfer to the intensive care unit (ICU). This study aimed to identify clinical factors that can predict patients at increased risk for delayed transfer to the ICU and the association of delayed ICU transfer with mortality. METHODS: This is a nested case-control study in a prospectively collected registry of patients with severe sepsis and septic shock at two EDs...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/28711881/clinical-utility-of-ykl-40-in-polymyositis-dermatomyositis-associated-interstitial-lung-disease
#8
Hironao Hozumi, Tomoyuki Fujisawa, Noriyuki Enomoto, Ran Nakashima, Yasunori Enomoto, Yuzo Suzuki, Masato Kono, Masato Karayama, Kazuki Furuhashi, Akihiro Murakami, Naoki Inui, Yutaro Nakamura, Tsuneyo Mimori, Takafumi Suda
OBJECTIVE: Interstitial lung disease (ILD) is involved in polymyositis/dermatomyositis (PM/DM), a disease associated with poor prognoses. Chitinase-3-like-1 protein (YKL-40) has pleiotropic biological activities involved in inflammation, cell proliferation, and tissue remodeling; however, the clinical application of YKL-40 remains limited. We investigated the clinical significance of YKL-40 in PM/DM-ILD. METHODS: Sixty-nine consecutive patients with PM/DM-ILD and 34 healthy controls were analyzed...
July 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28706240/gasoline-cars-produce-more-carbonaceous-particulate-matter-than-modern-filter-equipped-diesel-cars
#9
S M Platt, I El Haddad, S M Pieber, A A Zardini, R Suarez-Bertoa, M Clairotte, K R Daellenbach, R-J Huang, J G Slowik, S Hellebust, B Temime-Roussel, N Marchand, J de Gouw, J L Jimenez, P L Hayes, A L Robinson, U Baltensperger, C Astorga, A S H Prévôt
Carbonaceous particulate matter (PM), comprising black carbon (BC), primary organic aerosol (POA) and secondary organic aerosol (SOA, from atmospheric aging of precursors), is a highly toxic vehicle exhaust component. Therefore, understanding vehicle pollution requires knowledge of both primary emissions, and how these emissions age in the atmosphere. We provide a systematic examination of carbonaceous PM emissions and parameterisation of SOA formation from modern diesel and gasoline cars at different temperatures (22, -7 °C) during controlled laboratory experiments...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28700661/highly-sensitive-sandwich-immunoassay-and-immunochromatographic-test-for-the-detection-of-clostridial-epsilon-toxin-in-complex-matrices
#10
Cécile Féraudet-Tarisse, Christelle Mazuet, Serge Pauillac, Maren Krüger, Caroline Lacroux, Michel R Popoff, Brigitte G Dorner, Olivier Andréoletti, Marc Plaisance, Hervé Volland, Stéphanie Simon
Epsilon toxin is one of the four major toxins of Clostridium perfringens. It is the third most potent clostridial toxin after botulinum and tetanus toxins and is thus considered as a potential biological weapon classified as category B by the Centers for Disease Control and Prevention (CDC). In the case of a bioterrorist attack, there will be a need for a rapid, sensitive and specific detection method to monitor food and water contamination by this toxin, and for a simple human diagnostic test. We have produced and characterized five monoclonal antibodies against common epitopes of epsilon toxin and prototoxin...
2017: PloS One
https://www.readbyqxmd.com/read/28700223/metabolomics-profiling-to-determine-the-effect-of-postmortem-aging-on-color-and-lipid-oxidative-stabilities-of-different-bovine-muscles
#11
Danyi Ma, Yuan H Brad Kim, Bruce R Cooper, Ji-Hwan Oh, Hyonho Chun, Juhui Choe, J P Schoonmaker, Kolapo Matthew Ajuwon, Byungrok Min
The objective of this study was to identify the metabolites that could be associated with oxidative stability of aged bovine muscles. Three muscles (longissimus lumbrum (LL), semimembranosus (SM), and psoas major (PM)) from 7 beef carcasses at 1 day postmortem were divided into three sections and assigned to three aging periods (9, 16 and 23 days). While an increase in discoloration was found in all muscles with aging, LL was the most color/lipid oxidative stable, followed by SM and PM (P < 0.05). Lower myoglobin and non-heme iron contents were observed in LL compared to SM and PM (P < 0...
July 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28698096/differential-pulmonary-effects-of-wintertime-california-and-china-particulate-matter-in-healthy-young-mice
#12
Xiaolin Sun, Haiying Wei, Dominique E Young, Keith J Bein, Suzette M Smiley-Jewell, Qi Zhang, Ciara Catherine B Fulgar, Alejandro R Castañeda, Alexa K Pham, Wei Li, Kent E Pinkerton
Airborne particulate matter (PM) is associated with adverse cardiorespiratory effects. To better understand source-orientated PM toxicity, a comparative study of the biological effects of fine PM (diameter≤2.5μm, PM2.5) collected during the winter season from Shanxi Province, China, and the Central Valley, California, United States, was conducted. The overarching hypothesis for this study was to test whether the chemical composition of PM on an equal mass basis from two urban areas, one in China and one in California, can lead to significantly different effects of acute toxicity and inflammation in the lungs of healthy young mice...
July 8, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28697652/ask-the-experts-how-to-treat-individuals-with-spatial-neglect-a-survey-study
#13
Peii Chen, Marco Pitteri, Glen Gillen, Harsha Ayyala
PURPOSE: Spatial neglect (SN) impedes rehabilitation success and leaves long-term consequences. We asked experts to provide their opinions in addressing SN by scenario (ideal vs. reality) and by recovery phase (earliest, acute, subacute, and chronic). Experts were individuals who have assessed or treated patients with SN clinically. MATERIALS AND METHODS: This study was conducted using an anonymous survey on the Internet with 189 responders over 3 months. Located in 23 different countries, 127 experts of seven disciplines were included (occupational therapy, physical therapy, nursing, speech and language pathology or therapy, neurology, physical medicine and rehabilitation, and psychology or neuropsychology)...
July 11, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28693933/-partially-matched-us-senior-diagnostic-radiology-applicants-scope-of-the-problem-and-implications-for-applicants-residency-training-programs-and-the-academic-diagnostic-radiology-community
#14
Keith D Herr, Sravanthi Reddy, Elizabeth A Krupinski, Mark E Mullins, Christopher Straus
RATIONALE AND OBJECTIVES: Anecdotal reports have recently surfaced of an increase in the number of US senior diagnostic radiology (DR)-bound residency applicants who did not secure a preliminary year position through the Main Resident Match (the Match) of the National Resident Matching Program (NRMP), so-called "partial matches." This study sought to determine the scope of this phenomenon and address potential causes and solutions. MATERIALS AND METHODS: Publicly available and proprietary data from the National Resident Matching Program were analyzed from 2005-2016 to determine the number of partially matched US senior applicants, selectivity of DR residency training, availability of preliminary year positions, number of unique preliminary year applicants, distribution of preliminary year matches by successfully matched applicants in relevant specialties (DR, anesthesiology, dermatology, neurology, physical medicine and rehabilitation, and radiation oncology), and percentage of categorical training programs participating in the Match...
June 5, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28689511/evaluating-feasibility-and-acceptability-of-a-group-who-trans-diagnostic-intervention-for-women-with-common-mental-disorders-in-rural-pakistan-a-cluster-randomised-controlled-feasibility-trial
#15
M N Khan, S U Hamdani, A Chiumento, K Dawson, R A Bryant, M Sijbrandij, H Nazir, P Akhtar, A Masood, D Wang, E Wang, I Uddin, M V Ommeren, A Rahman
AIMS: The aim of this feasibility trial was to evaluate the feasibility and acceptability of the locally adapted Group Problem Management Plus (PM+) intervention for women in the conflict affected settings in Swat, Pakistan. METHODS: This mixed-methods study incorporated a quantitative component consisting of a two arm cluster randomised controlled feasibility trial, and qualitative evaluation of the acceptability of the Group PM+ to a range of stakeholder groups...
July 10, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28688989/involvement-of-oxidative-stress-and-calcium-signaling-in-airborne-particulate-matter-induced-damages-in-human-pulmonary-artery-endothelial-cells
#16
J Deweirdt, J F Quignard, B Crobeddu, A Baeza-Squiban, J Sciare, A Courtois, S Lacomme, E Gontier, B Muller, J P Savineau, R Marthan, C Guibert, I Baudrimont
Recent studies have revealed that particulate matter (PM) exert deleterious effects on vascular function. Pulmonary artery endothelial cells (HPAEC), which are involved in the vasomotricity regulation, can be a direct target of inhaled particles. Modifications in calcium homeostasis and oxidative stress are critical events involved in the physiopathology of vascular diseases. The objectives of this study were to assess the effects of PM2.5 on oxidative stress and calcium signaling in HPAEC. Different endpoints were studied, (i) intrinsic and intracellular production of reactive oxygen species (ROS) by the H2DCF-DA probe, (ii) intrinsic, intracellular and mitochondrial production of superoxide anion (O2(-)) by electronic paramagnetic resonance spectroscopy and MitoSOX probe, (iii) reactive nitrosative species (RNS) production by Griess reaction, and (vi) calcium signaling by the Fluo-4 probe...
July 5, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28684538/tissue-type-plasminogen-activator-regulates-macrophage-activation-and-innate-immunity
#17
Elisabetta Mantuano, Pardis Azmoon, Coralie Brifault, Michael A Banki, Andrew S Gilder, Wendy M Campana, Steven L Gonias
Tissue-type plasminogen activator (tPA) is the major intravascular activator of fibrinolysis and a ligand for receptors involved in cell-signaling. In cultured macrophages, tPA inhibits the response to lipopolysaccharide (LPS) by a pathway that apparently requires LDL Receptor-related Protein-1 (LRP1). Herein, we show that the mechanism by which tPA neutralizes LPS involves rapid reversal of IκBα phosphorylation. tPA independently induced transient IκBα phosphorylation and ERK1/2 activation in macrophages; however, these events that did not trigger inflammatory mediator expression...
July 6, 2017: Blood
https://www.readbyqxmd.com/read/28681742/the-effect-of-sensory-level-electrical-stimulation-of-the-masseter-muscle-in-early-stroke-patients-with-dysphagia-a-randomized-controlled-study
#18
Ebru K Umay, Atilay Yaylaci, Guleser Saylam, Ibrahim Gundogdu, Eda Gurcay, Dehen Akcapinar, Zeynep Kirac
BACKGROUND: Dysphagia is a serious cause of morbidity and mortality in stroke patients. AIMS: As the first study in literature, we aimed to evaluate the effects of sensory-level electrical stimulation (SES) to bilateral masseter muscles in early stroke patients with dysphagia. SETTINGS AND DESIGN: This study was conducted at the Physical Medicine and Rehabilitation Clinic of our hospital between 2013 and 2015. MATERIALS AND METHODS: Ninety-eight patients with dysphagia within the first month after ischemic stroke were included in this study...
July 2017: Neurology India
https://www.readbyqxmd.com/read/28680509/association-between-transported-asian-dust-and-outdoor-fungal-concentration-during-winter-in-a-rural-area-of-western-japan
#19
Kyoko Iwata, Masanari Watanabe, Jun Kurai, Naoto Burioka, Sachiko Nakamoto, Degejirihu Hantan, Eiji Shimizu
BACKGROUND: Recently, Asian dust (AD) has become a serious health problem and several studies have clearly proven that AD can aggravate asthma. However, it remains unclear as to which components of AD have a strong effect on the asthma exacerbation caused by AD exposure. Outdoor fungi can increase emergency department visits and hospitalization for asthma exacerbation and can aggravate asthma symptoms. Therefore, this study was aimed at investigating the relationship between AD and outdoor fungi and determining the potential of fungi to cause airborne particulate matter (PM)-related inflammatory responses...
2017: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://www.readbyqxmd.com/read/28680054/recent-increase-of-surface-particulate-matter-concentrations-in-the-seoul-metropolitan-area-korea
#20
Hyun Cheol Kim, Soontae Kim, Byeong-Uk Kim, Chun-Sil Jin, Songyou Hong, Rokjin Park, Seok-Woo Son, Changhan Bae, MinAh Bae, Chang-Keun Song, Ariel Stein
Recent changes of surface particulate matter (PM) concentration in the Seoul Metropolitan Area (SMA), South Korea, are puzzling. The long-term trend of surface PM concentration in the SMA declined in the 2000s, but since 2012 its concentrations have tended to incline, which is coincident with frequent severe hazes in South Korea. This increase puts the Korean government's emission reduction efforts in jeopardy. This study reports that interannual variation of surface PM concentration in South Korea is closely linked with the interannual variations of wind speed...
July 5, 2017: Scientific Reports
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