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https://www.readbyqxmd.com/read/28329930/-commuting-mode-specific-exposure-to-pm-2-5-in-urban-area-of-guangzhou
#1
X J Lyu, Z H Li, X Li, W L Zeng, P Yang, Q X Lin, J Y Zheng, X L Du, Y Z Gu, Y Q Zhao, R S Xie, T Liu, H L Lin, W J Ma
Objective: To find the differences in PM(2.5) exposure level in the context of four commuting modes (by walk, bicycle, bus and subway) in Guangzhou. Methods: The PM(2.5) exposure assessment was carried out from January to December 2015 in Guangzhou. PM(2.5) was measured by using SidePak individual dust meter (AM510, TSI Inc. USA) with time interval of 1 minute. Our measurement was taken on Monday, Wednesday, Friday and Sunday in the second week of each month and the samples were collected in the morning (07:00-09:00), afternoon (11:00-13:00) and evening (17:00-19:00)...
March 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28329926/-acute-effect-of-fine-particulate-matters-on-daily-cardiovascular-disease-mortality-in-seven-cities-of-china
#2
R M Liang, P Yin, L J Wang, Y C Li, J M Liu, Y N Liu, J L You, J L Qi, M G Zhou
Objective: To explore the effect of fine particulate matters with an aerodynamic diameter less than 2.5 μm (PM(2.5)) on daily cardiovascular disease mortality in seven cities of China. Methods: Daily average concentrations of PM(2.5), cardiovascular disease mortality data and environmental data were collected from January 1, 2013 to December 31, 2015 in seven cities of China, including Shijiazhuang, Haerbin, Shanghai, Wuhan, Guangzhou, Chengdu and Xi' an. We linked generalized additive model with Quasi-Poisson distribution to evaluate the association between daily concentrations of PM(2...
March 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28323759/hypercapnia-caused-by-a-therapeutic-dosage-of-pregabalin-in-a-tetraplegic-patient-with-cervical-spinal-cord-injury
#3
Kyung Hee Do, Eun Jung Choi, Min Cheol Chang, Hea-Eun Yang
Pregabalin is often used for the treatment of neuropathic pain in patients with spinal cord injury (SCI). We reported a patient with C5 [S(C5/C6)] ASIA Impairment Scale C SCI due to cervical myelopathy who presented CO2 retention when taking a therapeutic dosage of pregabalin. An 88-year-old patient with cervical SCI was transferred to the department of physical medicine and rehabilitation. When he had transferred, his neuropathic pain had been treated with 150-mg pregabalin per day (75 mg twice a day); however, he still exhibited severe neuropathic pain with a Numeric Pain Rating Scale score of 7 to 8...
March 20, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28323582/white-matter-integrity-in-high-altitude-pilots-exposed-to-hypobaria
#4
Stephen A McGuire, Goldie R E Boone, Paul M Sherman, David F Tate, Joe D Wood, Beenish Patel, George Eskandar, S Andrea Wijtenburg, Laura M Rowland, Geoffrey D Clarke, Patrick M Grogan, John H Sladky, Peter V Kochunov
INTRODUCTION: Nonhypoxic hypobaric (low atmospheric pressure) occupational exposure, such as experienced by U.S. Air Force U-2 pilots and safety personnel operating inside altitude chambers, is associated with increased subcortical white matter hyperintensity (WMH) burden. The pathophysiological mechanisms underlying this discrete WMH change remain unknown. The objectives of this study were to demonstrate that occupational exposure to nonhypoxic hypobaria is associated with altered white matter integrity as quantified by fractional anisotropy (FA) measured using diffusion tensor imaging and relate these findings to WMH burden and neurocognitive ability...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28320919/pan-cancer-analysis-distinguishes-transcriptional-changes-of-aneuploidy-from-proliferation
#5
Christopher Buccitelli, Lorena Salgueiro, Konstantina Rowald, Rocio Sotillo, Balca R Mardin, Jan O Korbel
Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs and PMs could be thought to associate with distinct signatures given their different formation mechanisms. Here we test this notion by systematically investigating SCNA, PM, and transcriptome data from 2660 cancer patients representing 11 tumor types...
March 20, 2017: Genome Research
https://www.readbyqxmd.com/read/28290668/surface-assay-for-specific-detection-of-soluble-amyloid-oligomers-utilizing-pronucleon-peptides-instead-of-antibodies
#6
Evgenia G Matveeva, Jonathan R Moll, Mariam M Khan, Richard B Thompson, Richard O Cliff
Immunoassays such as enzyme-linked immunosorbent assays (ELISAs) are widely used for diagnostics; however, antibodies as detection reagents may be insufficiently selective and have other shortcomings. We present a novel non-antibody-based detection method based on binding target molecules to peptides (used as recognition molecules): a surface assay for A-β oligomers employing a peptide comprising amino acid residues of the human β-amyloid protein (Pronucleon peptide) as the capture agent. For the sake of convenience, we term this the "Pronucleon peptide-linked immunosorbent assay", or PLISA...
March 21, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28289646/effectiveness-of-ear-splint-therapy-for-ear-deformities
#7
Ji Eun Woo, Yul-Hyun Park, Eun Ji Park, Kyu Yong Park, Sun Hee Kim, Shin-Young Yim
OBJECTIVE: To present our experience with ear splint therapy for babies with ear deformities, and thereby demonstrate that this therapy is an effective and safe intervention without significant complications. METHODS: This was a retrospective study of 54 babies (35 boys and 19 girls; 80 ears; age ≤3 months) with ear deformities who had received ear splint therapy at the Center for Torticollis, Department of Physical Medicine and Rehabilitation, Ajou University Hospital between December 2014 and February 2016...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28289631/effect-of-a-caregiver-s-education-program-on-stroke-rehabilitation
#8
Sang-Eun Hong, Chang-Hwan Kim, Ee-Jin Kim, Kyung-Lim Joa, Tae-Hyun Kim, Sang-Keun Kim, Hee-Jun Han, Eui-Chang Lee, Han-Young Jung
OBJECTIVE: To evaluate effects of caregiver's education program on their satisfaction, as well as patient functional recovery, performed in addition to daily conventional rehabilitation treatment. METHODS: Three hundred eleven subjects diagnosed with first-onset stroke and transferred to the Department of Physical Medicine and Rehabilitation of Inha University Hospital were surveyed. In 2015, caregivers attended an education program for acute and subacute stroke patients...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28287212/-the-pacemaker-and-implantable-cardioverter-defibrillator-registry-of-the-italian-association-of-arrhythmology-and-cardiac-pacing-annual-report-2015
#9
Alessandro Proclemer, Massimo Zecchin, Antonio D'Onofrio, Giuseppe Boriani, Giovanni Luca Botto, Domenico Facchin, Luca Rebellato, Marco Ghidina, Giulia Bianco, Emanuela Bernardelli, Elsa Pucher, Dario Gregori
BACKGROUND: The pacemaker (PM) and implantable cardioverter-defibrillator (ICD) Registry of the Italian Association of Arrhythmology and Cardiac Pacing (AIAC) monitors the main epidemiological data in real-world practice. The survey for the 2015 activity collects information about demographics, clinical characteristics, main indications for PM/ICD therapy and device types from the Italian collaborating centers. METHODS: The Registry collects prospectively national PM and ICD implantation activity on the basis of European cards...
January 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28286724/a-questionnaire-based-survey-of-physical-medicine-and-rehabilitation-residency-training-in-pakistan
#10
Farooq A Rathore, Aamir W Butt, Nabila Soomro, Noreen Akhtar
Pakistan is one of the three countries in South East Asia that has an active postgraduate physical medicine and rehabilitation (PM&R) training program. College of Physicians and Surgeons Pakistan (CPSP) offers a four-year structured training program in PM&R. It consists of clinical teaching, lectures, rotations in other specialties, and writing a research dissertation. The aim of this survey was to provide an objective analysis of the current PM&R training program, including the facilities available for training, the participation of residents in academic activities, and their participation in different PM&R procedures...
January 31, 2017: Curēus
https://www.readbyqxmd.com/read/28286053/onabotulinumtoxina-for-lower-limb-spasticity-guidance-from-a-delphi-panel-approach
#11
Alberto Esquenazi, Abraham Alfaro, Ziyad Ayyoub, David Charles, Khashayar Dashtipour, Glenn D Graham, John R McGuire, Ib R Odderson, Atul T Patel, David M Simpson
BACKGROUND: OnabotulinumtoxinA is approved for the treatment of upper and lower limb spasticity in adults. Guidance on common postures and onabotulinumtoxinA injection paradigms for upper limb spasticity has been developed using a Delphi Panel. However, similar guidance for lower limb spasticity has not been established. OBJECTIVE: To define a clinically recommended treatment paradigm using onabotulinumtoxinA for each common posture among patients with post-stroke lower-limb spasticity (PSLLS); to identify the most common PSLLS aggregate postures...
March 7, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28278029/overview-of-surface-measurements-and-spatial-characterization-of-submicron-particulate-matter-during-the-discover-aq-2013-campaign-in-houston
#12
Y J Leong, N P Sanchez, H W Wallace, B Karakurt Cevik, C S Hernandez, Y Han, J H Flynn, P Massoli, C Floerchinger, E C Fortner, S Herndon, J K Bean, L Hildebrandt Ruiz, W Jeon, Y Choi, B Lefer, R J Griffin
The sources of submicron particulate matter (PM1) remain poorly characterized in the industrialized city of Houston. A mobile sampling approach was used to characterize PM1 composition and concentration across Houston based on high time resolution measurements of non-refractory PM1 and trace gases during the DISCOVER-AQ Texas 2013 campaign. Two pollution zones with marked differences in PM1 levels, character, and dynamics were established based on cluster analysis of organic aerosol mass loadings sampled at sixteen sites...
February 28, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28274842/rehabilitation-traumatology-a-narrative-review
#13
REVIEW
Donna Bloodworth, Sindhu Pandit, Patrick Mullan, Faye C Tan
Rehabilitation Traumatology has developed within Physical Medicine and Rehabilitation as a specialized area of knowledge in which the physiatrist works with the Traumatology team to enhance the functional outcome of trauma patients. The American Heritage Dictionary defines Traumatology as "the branch of medicine that deals with the treatment of serious wounds, injuries, and disabilities" [1]. It defines rehabilitate as "to restore to good health or useful life, as through therapy and education" [1]. Thus the authors propose Rehabilitation Traumatology be "the branch of medicine that deals with the treatment of serious wounds, injuries, and disabilities", "to restore (the patient) to good health or useful life"...
March 5, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28273596/challenges-in-estimating-health-effects-of-indoor-exposures-to-outdoor-particles-considerations-for-regional-differences
#14
Otto Hänninen, Isabell Rumrich, Arja Asikainen
Ambient air pollution is a leading environmental risk factor causing substantial losses of life and significant morbidity. Concentration-response (CR) functions used globally to estimate such effects are largely based on ambient epidemiology, using centrally monitored outdoor air quality as an exposure indicator and various indices of population health as an outcome. Similar common understanding is mostly missing regarding indoor exposures. Less studied are health impact modifying factors such as particle size, infiltration, time-activity and population differences...
March 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28268314/a-telemonitoring-platform-for-the-investigation-of-blood-pressure-profiles-in-pacemaker-patients
#15
G Calcagnini, E Mattei, R Quaglione, E De Ruvo, G Biancalana, G Pavone, A Gargaro, L Calo, F Ammirati, F Censi
Rate responsive pacemakers (PM) use different strategies to adapt the patient paced rate, with the aim of having the best hemodynamic performance in response to internal or external conditions. Closed-loop stimulation (CLS) uses intracardiac impedance as a sensor principle. The evaluation of impact of different pacing modalities and technologies on the blood pressure (BP) profiles is mainly investigated in short-term laboratory settings, mainly due to the need of reliable daily-based BP values. The impact of CLS pacing on systemic blood pressure (BP) has been studied on short term basis, but data on long term effects are scarse...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265170/reliability-and-validity-of-the-turkish-version-of-the-fibromyalgia-rapid-screening-tool-first
#16
Reyhan Celiker, Lale Altan, Aylin Rezvani, Ilknur Aktas, Nurettin Tastekin, Erbil Dursun, Nigar Dursun, Selda Sarıkaya, Senay Ozdolap, Kenan Akgun, Coskun Zateri, Murat Birtane
[Purpose] An easy-to-use, psychometrically validated screening tool for fibromyalgia is needed. This study aims to evaluate the reliability and validity of the Turkish version of the Fibromyalgia Rapid Screening Tool by correlating it with 2013 American College of Rheumatology alternative diagnostic criteria and the Hospital Anxiety and Depression Scale. [Subjects and Methods] Subjects were 269 Physical Medicine and Rehabilitation clinic outpatients. Patients completed a questionnaire including the Fibromyalgia Rapid Screening Tool (twice), 2013 American College of Rheumatology alternative diagnostic criteria, and the Hospital Anxiety and Depression Scale...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28264819/phosphoinositides-and-membrane-targeting-in-cell-polarity
#17
Gerald R Hammond, Yang Hong
Selective enrichment of the polyphosphoinositides (PPIn), such as PtdIns(4,5)P2 and PtdIns4P, helps to determine the identity of the plasma membrane (PM) and regulates many aspects of cell biology through a vast number of protein effectors. Polarity proteins had long been assumed to be non-PPIn-binding proteins that mainly associate with PM/cell cortex through their extensive protein-protein interaction network. However, recent studies began to reveal that several key polarity proteins electrostatically bind to PPIn through their positively charged protein domains or structures and such PPIn-binding property is essential for their direct and specific attachment to PM...
March 6, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28260332/-impact-of-atmospheric-particulate-matter-at-different-period-of-gestation-on-low-birth-weight-a-meta-analysis
#18
R J Feng, R Wu, P R Zhong, X J Tian, X Long, C F Fan, L Ma
Objective: To analyze the influence of atmospheric particulate matters (PM(2.5) and PM(10)) on low-birth-weight (LBW) infants at different periods of gestation. Methods: We conducted a systematic literature search for 2 471 articles related to particulate matter and LBW published from January 1st 2000 to January 1st 2016 using the PubMed, Cochrane Library, Web of Science, Science Direct, Chinese Web of Knowledge, Wanfang and Weipu, and the keywords were" air pollution" , "adverse birth outcomes" , "adverse pregnancy outcomes" , "low birth weight/LBW" ...
March 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28256889/94%C3%A2-%C3%AE-decay-half-lives-of-neutron-rich-_-55-cs-to-_-67-ho-experimental-feedback-and-evaluation-of-the-r-process-rare-earth-peak-formation
#19
J Wu, S Nishimura, G Lorusso, P Möller, E Ideguchi, P-H Regan, G S Simpson, P-A Söderström, P M Walker, H Watanabe, Z Y Xu, H Baba, F Browne, R Daido, P Doornenbal, Y F Fang, G Gey, T Isobe, P S Lee, J J Liu, Z Li, Z Korkulu, Z Patel, V Phong, S Rice, H Sakurai, L Sinclair, T Sumikama, M Tanaka, A Yagi, Y L Ye, R Yokoyama, G X Zhang, T Alharbi, N Aoi, F L Bello Garrote, G Benzoni, A M Bruce, R J Carroll, K Y Chae, Z Dombradi, A Estrade, A Gottardo, C J Griffin, H Kanaoka, I Kojouharov, F G Kondev, S Kubono, N Kurz, I Kuti, S Lalkovski, G J Lane, E J Lee, T Lokotko, G Lotay, C-B Moon, H Nishibata, I Nishizuka, C R Nita, A Odahara, Zs Podolyák, O J Roberts, H Schaffner, C Shand, J Taprogge, S Terashima, Z Vajta, S Yoshida
The β-decay half-lives of 94 neutron-rich nuclei ^{144-151}Cs, ^{146-154}Ba, ^{148-156}La, ^{150-158}Ce, ^{153-160}Pr, ^{156-162}Nd, ^{159-163}Pm, ^{160-166}Sm, ^{161-168}Eu, ^{165-170}Gd, ^{166-172}Tb, ^{169-173}Dy, ^{172-175}Ho, and two isomeric states ^{174m}Er, ^{172m}Dy were measured at the Radioactive Isotope Beam Factory, providing a new experimental basis to test theoretical models. Strikingly large drops of β-decay half-lives are observed at neutron-number N=97 for _{58}Ce, _{59}Pr, _{60}Nd, and _{62}Sm, and N=105 for _{63}Eu, _{64}Gd, _{65}Tb, and _{66}Dy...
February 17, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28244947/intermediate-acting-nondepolarizing-neuromuscular-blocking-agents-and-risk-of-postoperative-30-day-morbidity-and-mortality-and-long-term-survival
#20
Michael R Bronsert, William G Henderson, Terri G Monk, Joshua S Richman, Jennifer D Nguyen, John T Sum-Ping, Michael P Mangione, Binh Higley, Karl E Hammermeister
BACKGROUND: Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the association between NNMBD use with or without neostigmine reversal and postoperative morbidity and mortality. METHODS: This is a retrospective observational study of 11,355 adult patients undergoing general anesthesia for noncardiac surgery at 5 Veterans Health Administration (VA) hospitals...
February 24, 2017: Anesthesia and Analgesia
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