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transcranial magnetic stimulation

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https://www.readbyqxmd.com/read/29050384/stimulating-thought-a-functional-mri-study-of-transcranial-direct-current-stimulation-in-schizophrenia
#1
Natasza D Orlov, Owen O'Daly, Derek K Tracy, Yusuf Daniju, John Hodsoll, Lorena Valdearenas, John Rothwell, Sukhi S Shergill
Individuals with schizophrenia typically suffer a range of cognitive deficits, including prominent deficits in working memory and executive function. These difficulties are strongly predictive of functional outcomes, but there is a paucity of effective therapeutic interventions targeting these deficits. Transcranial direct current stimulation is a novel neuromodulatory technique with emerging evidence of potential pro-cognitive effects; however, there is limited understanding of its mechanism. This was a double-blind randomized sham controlled pilot study of transcranial direct current stimulation on a working memory (n-back) and executive function (Stroop) task in 28 individuals with schizophrenia using functional magnetic resonance imaging...
September 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29046429/paired-corticospinal-motoneuronal-stimulation-increases-maximal-voluntary-activation-of-human-adductor-pollicis
#2
Jessica M D'Amico, Siobhan C Donges, Janet L Taylor
Paired corticospinal-motoneuronal stimulation (PCMS), which delivers repeated pairs of transcranial magnetic stimuli (TMS) and maximal motor nerve stimuli, can alter corticospinal transmission to low threshold motoneurones in the human spinal cord. To determine whether similar changes occur for high threshold motoneurones, we tested whether maximal voluntary activation and force can be affected by PCMS in healthy individuals. On two separate days, healthy participants (n=14) performed brief thumb adduction MVCs before and after a control protocol (TMS only) or PCMS designed to facilitate corticospinal transmission to adductor pollicis...
October 18, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29045857/a-systematic-review-and-meta-analysis-on-the-use-of-repetitive-transcranial-magnetic-stimulation-for-spasticity-post-stroke
#3
REVIEW
A McIntyre, M Mirkowski, S Thompson, A M Burhan, T Miller, R Teasell
BACKGROUND: Spasticity is a common and potentially debilitating complication that develops after stroke, arising in approximately 30% of patients. OBJECTIVE: To evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in improving spasticity after stroke. DESIGN: Meta-analysis and systematic review. SETTING: N/A PATIENTS: A total of 273 post-stroke (hemorrhagic=123, ischemic=150) participants were included with sample sizes ranging from 5 to 80...
October 15, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29044872/transcranial-magnetic-stimulation-of-right-inferior-parietal-cortex-causally-influences-prefrontal-activation-for-visual-detection
#4
Joana Leitão, Axel Thielscher, Hwee Ling Lee, Johannes Tuennerhoff, Uta Noppeney
For effective interactions with the environment the brain needs to form perceptual decisions based on noisy sensory evidence. Accumulating evidence suggests that perceptual decisions are formed by widespread interactions amongst sensory areas representing the noisy sensory evidence and fronto-parietal areas integrating the evidence into a decision variable that is compared to a decisional threshold. This concurrent transcranial magnetic stimulation (TMS)-fMRI study applied 10 Hz bursts of four TMS (or Sham) pulses to the intraparietal sulcus (IPS) to investigate the causal influence of IPS on the neural systems involved in perceptual decision making...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29042299/non-pharmacological-interventions-for-spasticity-in-adults-an-overview-of-systematic-reviews
#5
REVIEW
Fary Khan, Bhasker Amatya, Djamel Bensmail, Alain Yelnik
OBJECTIVES: Spasticity causes significant long-term disability-burden, requiring comprehensive management. This review evaluates evidence from published systematic reviews of clinical trials for effectiveness of non-pharmacological interventions for improved spasticity outcomes. METHODS: Data sources: A literature search was conducted using medical and health science electronic (MEDLINE, EMBASE, CINAHL, PubMed, and the Cochrane Library) databases for published systematic reviews up to 15(th) June 2017...
October 14, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29040922/plasticity-induced-by-non-invasive-transcranial-brain-stimulation-a-position-paper
#6
REVIEW
Ying-Zu Huang, Ming-Kue Lu, Andrea Antal, Joseph Classen, Michael Nitsche, Ulf Ziemann, Michael Ridding, Masashi Hamada, Yoshikazu Ugawa, Shapour Jaberzadeh, Antonio Suppa, Walter Paulus, John Rothwell
Several techniques and protocols of non-invasive transcranial brain stimulation (NIBS), including transcranial magnetic and electrical stimuli, have been developed in the past decades. Non-invasive transcranial brain stimulation may modulate cortical excitability outlasting the period of non-invasive transcranial brain stimulation itself from several minutes to more than one hour. Quite a few lines of evidence, including pharmacological, physiological and behavioral studies in humans and animals, suggest that the effects of non-invasive transcranial brain stimulation are produced through effects on synaptic plasticity...
September 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29036851/a-novel-low-cost-approach-for-navigated-transcranial-magnetic-stimulation
#7
Jakob Rodseth, Edward P Washabaugh, Chandramouli Krishnan
BACKGROUND: Transcranial magnetic stimulation (TMS) is commonly used for assessing or modulating brain excitability. However, the credibility of TMS outcomes depends on accurate and reliable coil placement during stimulation. Navigated TMS systems can address this issue, but these systems are expensive for routine use in clinical and research environments. OBJECTIVE: The purpose of this study was to provide a high-quality open source framework for navigated TMS and test its reliability and accuracy using standard TMS procedures...
October 9, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29035887/valeriana-officinalis-root-extract-modulates-cortical-excitatory-circuits-in-humans
#8
Ludovico Mineo, Carmen Concerto, Dhaval Patel, Tyrone Mayorga, Michael Paula, Eileen Chusid, Eugenio Aguglia, Fortunato Battaglia
BACKGROUND: Valeriana officinalis extract (VE) is a popular herbal medicine used for the treatment of anxiety and sleep disorders. Although the anxiolytic and sedative effects are mainly attributed to the modulation of GABA-ergic transmission, the mechanism of action has not been fully investigated in humans. Noninvasive brain stimulation protocols can be used to elucidate the mechanisms of action of psychoactive substances at the cortical level in humans. In this study, we investigated the effects of a single dose of VE on cortical excitability as assessed with transcranial magnetic stimulation (TMS)...
October 17, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29034483/effect-of-sensory-and-motor-connectivity-on-hand-function-in-pediatric-hemiplegia
#9
Disha Gupta, Alexandre Barachant, Andrew M Gordon, Claudio Ferre, Hsing-Ching Kuo, Jason B Carmel, Kathleen M Friel
OBJECTIVE: We tested the hypothesis that somatosensory system injury would more strongly affect movement than motor system injury in children with unilateral cerebral palsy (USCP). This hypothesis was based on how somatosensory and corticospinal circuits adapt to injury during development: while the motor system can maintain connections to the impaired hand from the uninjured hemisphere, this doesn't occur in the somatosensory system. As a corollary, cortical injury strongly impairs sensory function, so we hypothesized that cortical lesions would impair hand function more than subcortical lesions...
October 16, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29032397/correction-to-extent-and-location-of-the-excitatory-and-inhibitory-cortical-hand-representation-maps-a-navigated-transcranial-magnetic-stimulation-study
#10
Minna Pitkänen, Elisa Kallioniemi, Petro Julkunen
The original version of this article unfortunately contained an error. An error in the transformation between coordinate systems used to derive part of the results has been noticed.
October 14, 2017: Brain Topography
https://www.readbyqxmd.com/read/29032089/transcranial-magnetic-stimulation-in-basic-and-clinical-neuroscience-a-comprehensive-review-of-fundamental-principles-and-novel-insights
#11
REVIEW
Antoni Valero-Cabré, Julià Amengual, Chloé Stengel, Alvaro Pascual-Leone, Olivier A Coubard
Non-invasive brain stimulation methods, such as Transcranial Magnetic Stimulation (TMS), are widely used worldwide to make causality-based inferences about brain-behavior interactions. TMS-based clinical applications have been shown promising to treat neurological or psychiatric diseases. TMS works by inducing non-invasively electric currents in localized cortical regions thus modulating their excitability levels and ongoing activity patterns depending on stimulation settings: frequency, number of pulses, train duration and intertrain intervals...
October 12, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29031601/enhancing-generalization-of-visuomotor-adaptation-by-inducing-use-dependent-learning
#12
Yuming Lei, Shancheng Bao, Monica A Perez, Jinsung Wang
Learning a motor task in one condition typically generalizes to another, although it is unclear why it generalizes substantially in certain situations, but only partially in other situations (e.g., across movement directions and motor effectors). Here, we demonstrate that generalization of motor learning across directions and effectors can be enhanced substantially by inducing use-dependent learning, that is, by having subjects experience motor actions associated with a desired trajectory repeatedly during reaching movements...
October 11, 2017: Neuroscience
https://www.readbyqxmd.com/read/29030110/where-and-what-tms-activates-experiments-and-modeling
#13
Ilkka Laakso, Takenobu Murakami, Akimasa Hirata, Yoshikazu Ugawa
BACKGROUND: Despite recent developments in navigation and modeling techniques, the type and location of the structures that are activated by transcranial magnetic stimulation (TMS) remain unknown. OBJECTIVE: We studied the relationships between electrophysiological measurements and electric fields induced in the brain to locate the TMS activation site. METHODS: The active and resting motor thresholds of the first dorsal interosseous muscle were recorded in 19 subjects (7 female, 12 male, age 22 ± 4 years) using anteromedially oriented monophasic TMS at multiple locations over the left primary motor cortex (M1)...
September 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29024263/field-distribution-of-transcranial-static-magnetic-stimulation-in-realistic-human-head-model
#14
Joseph J Tharayil, Stefan M Goetz, John M Bernabei, Angel V Peterchev
OBJECTIVE: The objective of this work was to characterize the magnetic field (B-field) that arises in a human brain model from the application of transcranial static magnetic field stimulation (tSMS). MATERIALS AND METHODS: The spatial distribution of the B-field magnitude and gradient of a cylindrical, 5.08 cm × 2.54 cm NdFeB magnet were simulated in air and in a human head model using the finite element method and calibrated with measurements in air. The B-field was simulated for magnet placements over prefrontal, motor, sensory, and visual cortex targets...
October 10, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29023249/priming-with-1-hz-rtms-over-contralesional-leg-motor-cortex-does-not-increase-the-rate-of-regaining-ambulation-within-3-months-of-stroke-a-randomized-controlled-trial
#15
Ying-Zu Huang, Li-Fong Lin, Kwang-Hwa Chang, Chaur-Jong Hu, Tsan-Hon Liou, Yen-Nung Lin
BACKGROUND: The potential benefits of repetitive transcranial magnetic stimulation (rTMS), applied either alone or as a combination treatment, on recovery of lower extremities after stroke have been insufficiently studied. OBJECTIVE: To evaluate the effect of priming with 1-Hz rTMS over contralesional leg motor area with a double cone coil prior physical therapy (PT) on regaining ambulation. METHODS: Thirty-eight subacute stroke patients with significant leg disabilities were randomly assigned into the experimental (E) group or control (C) group to receive a 15-min real or sham 1-Hz rTMS, respectively, over the contralesional motor cortex representing the quadriceps muscle followed by 45-min PT for 15 sessions over 3 weeks...
October 10, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29021752/potential-impact-of-geomagnetic-field-in-transcranial-magnetic-stimulation-for-the-treatment-of-neurodegenerative-diseases
#16
Kwon-Seok Chae, Yong-Hwan Kim
Throughout the long history of various therapeutic trials of transcranial magnetic stimulation (TMS), some TMS protocols have been reported to be clearly effective in the treatment of neurodegenerative diseases. Despite promising results from repetitive TMS (rTMS) using low frequency electromagnetic fields (EMFs) for neurodegenerative diseases, the low reproducibility has hampered the clinical applications of rTMS. Here, based on the notion of radical pair mechanism explaining magnetoreception in living organisms, we propose a new perspective that rTMS with controlled geomagnetic field (rTMS-GMF) can be an efficient and reproducible therapeutic approach for neurodegenerative diseases...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29021749/phase-dependent-modulation-of-signal-transmission-in-cortical-networks-through-tacs-induced-neural-oscillations
#17
Kristoffer D Fehér, Masahito Nakataki, Yosuke Morishima
Oscillatory neural activity is considered a basis of signal transmission in brain networks. However, the causal role of neural oscillations in regulating cortico-cortical signal transmission has so far not been directly demonstrated. To date, due to methodological limitations, studies on the online modulatory mechanisms of transcranial alternating current stimulation (tACS)-induced neural oscillations are confined to the primary motor cortex. To address the causal role of oscillatory activity in modulating cortico-cortical signal transmission, we have established a new method using concurrent tACS, transcranial magnetic stimulation (TMS) and electroencephalography (EEG)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29021352/successful-motor-mapping-with-transcranial-magnetic-stimulation-in-an-infant-a-case-report
#18
Shalini Narayana, Basanagoud Mudigoudar, Abbas Babajani-Feremi, Asim F Choudhri, Frederick A Boop
No abstract text is available yet for this article.
October 11, 2017: Neurology
https://www.readbyqxmd.com/read/29020806/transcranial-static-magnetic-field-stimulation-tsms-of-the-visual-cortex-decreases-experimental-photophobia
#19
Elena Lozano-Soto, Vanesa Soto-León, Simona Sabbarese, Lara Ruiz-Alvarez, Margarita Sanchez-Del-Rio, Juan Aguilar, Bryan A Strange, Guglielmo Foffani, Antonio Oliviero
Background Transcranial static magnetic field stimulation (tSMS) reduces cortical excitability in humans. Methods The objective of this study was to determine whether tSMS over the occipital cortex is effective in reducing experimental photophobia. In a sham-controlled double-blind crossover study, tSMS (or sham) was applied for 10 minutes with a cylindrical magnet on the occiput of 20 healthy subjects. We assessed subjective discomfort induced by low-intensity and high-intensity visual stimuli presented in a dark room before, during and after tSMS (or sham)...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29020606/using-tdcs-priming-to-improve-brain-function-can-metaplasticity-provide-the-key-to-boosting-outcomes
#20
REVIEW
Roanne Hurley, Liana Machado
Transcranial direct current stimulation (tDCS) has been trialled by many researchers attempting to improve brain function. Outcomes have been quite variable with seemingly similar protocols yielding either inconsistent or insufficiently robust improvements for clinical translation. A potentially fruitful avenue for increasing benefits conferred by tDCS stems from findings from motor and visual cortex studies that indicate tDCS priming prior to a subsequent period of stimulation (tDCS or transcranial magnetic stimulation) can in some cases boost outcomes compared to protocols without priming...
October 8, 2017: Neuroscience and Biobehavioral Reviews
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