keyword
MENU ▼
Read by QxMD icon Read
search

breast density bmi

keyword
https://www.readbyqxmd.com/read/28331747/the-relationship-between-bone-mineral-density-and-estrogen-receptor-positivity-in-patients-with-breast-cancer
#1
Zeynep Erdoğan İyigün, Kezban Nur Pilancı, Fatmagül Kuşku Çabuk, Serkan İlgün, Çetin Ordu, Tomris Duymaz, Gül Alço, Filiz Çelebi, Dauren Sarsenov, Filiz İzci, Alper Öztürk, Filiz Ağaçayak, Ülkühan İner Köksal, Fatma Aktepe, Yeşim Eralp, Vahit Özmen
OBJECTIVE: The effect of estrogen on bone mineral density (BMD) and breast cancer has been known for a long time. The aim of this study was to compare of the BMD of patients with breast cancer and healthy individuals, and to investigate the degree of correlation of estrogen receptor (ER) with BMD. MATERIALS AND METHODS: Seventy-one patients with postmenopausal breast cancer and 79 healthy dividuals were included in the study. The patient demographics (age, menopause age, body mass index, number of children, BMD, Z scores, and estrogen status for breast cancer patients) were taken from hospital records...
July 2016: J Breast Health (2013)
https://www.readbyqxmd.com/read/28288659/a-clinical-model-for-identifying-the-short-term-risk-of-breast-cancer
#2
Mikael Eriksson, Kamila Czene, Yudi Pawitan, Karin Leifland, Hatef Darabi, Per Hall
BACKGROUND: Most mammography screening programs are not individualized. To efficiently screen for breast cancer, the individual risk of the disease should be determined. We describe a model that could be used at most mammography screening units without adding substantial cost. METHODS: The study was based on the Karma cohort, which included 70,877 participants. Mammograms were collected up to 3 years following the baseline mammogram. A prediction protocol was developed using mammographic density, computer-aided detection of microcalcifications and masses, use of hormone replacement therapy (HRT), family history of breast cancer, menopausal status, age, and body mass index...
March 14, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28258052/kernel-density-estimation-as-a-measure-of-environmental-exposure-related-to-insulin-resistance-in-breast-cancer-survivors
#3
Marta M Jankowska, Loki Natarajan, Suneeta Godbole, Kristin Meseck, Dorothy D Sears, Ruth E Patterson, Jacqueline Kerr
BACKGROUND: Environmental factors may influence breast cancer, however most studies have measured environmental exposure in neighborhoods around home residences (static exposure). We hypothesize that tracking environmental exposures over time and space (dynamic exposure) is key to assessing total exposure. This study compares breast cancer survivors' exposure to walkable and recreation-promoting environments using dynamic Global Positioning System (GPS) and static home-based measures of exposure in relation to insulin resistance...
March 3, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28210549/evaluation-of-discrepancies-in-weights-of-fresh-and-fixed-specimens-in-breast-surgery-a-retrospective-cohort-study
#4
Dinesh Thekkinkattil
BACKGROUND: Handling of breast specimen is not well monitored and there is limited data on the impact of fixative solutions on specimen weights. Weight of resected breast tissue acts as a guide for future reconstructive and symmetrisation procedures. The aim is to quantitatively evaluate the discrepancies in weight of fresh breast specimen and the weight of specimen after being kept in a fixative solution for a variable length of time. METHODS: Single centre retrospective cohort study including patients undergone breast surgery for both diagnostic and therapeutic purposes between January of 2013 and June 2015...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28199328/association-of-pvuii-and-xbai-polymorphisms-on-estrogen-receptor-alpha-esr1-gene-to-changes-into-serum-lipid-profile-of-post-menopausal-women-effects-of-aging-body-mass-index-and-breast-cancer-incidence
#5
Neuza Felix Gomes-Rochette, Letícia Soncini Souza, Bruno Otoni Tommasi, Diego França Pedrosa, Sérgio Ragi Eis, Irani do Carmo Francischetto Fin, Fernando Luiz Herkenhoff Vieira, Jones Bernardes Graceli, Letícia Batista Azevedo Rangel, Ian Victor Silva
Estrogen is a steroidal hormone involved in several physiological functions in the female body including regulation of serum lipid metabolism and breast cancer (BC). Estrogen actions on serum lipids mostly occur through its binding to intracellular Estrogen Receptor alpha (ERalpha) isoform, expressed in most of tissues. This gene (ESR1) exhibit many polymorphic sites (SNPs) located either on translated and non-translated regions that regulate ERalpha protein expression and function. This paper aimed to investigate the association of two intronic SNPs of ESR1 gene, namely c454-397T>C (PvuII) and c454-351A>G (XbaI) to alterations in serum levels of total cholesterol (T-chol), total lipid (TL), low density lipoprotein cholesterol (LDL), high density lipoprotein (HDL), and triglycerides (TG) in a cohort of post-menopausal women...
2017: PloS One
https://www.readbyqxmd.com/read/28160159/aspirin-use-is-associated-with-lower-mammographic-density-in-a-large-screening-cohort
#6
REVIEW
Marie E Wood, Brian L Sprague, Andrew Oustimov, Marie B Synnstvedt, Melissa Cuke, Emily F Conant, Despina Kontos
BACKGROUND: Observational and biologic studies suggest that aspirin is a promising prevention therapy for breast cancer. However, clinical trials to date have not corroborated this evidence, potentially due to study design. We evaluated the effect of aspirin on mammographic density (MD), an established modifiable risk factor for breast cancer. METHODS: Electronic medical records from the University of Pennsylvania were evaluated for women who underwent screening mammography, saw their primary care provider, and had a confirmed list of medications during 2012-2013...
February 4, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28154107/impact-of-social-and-built-environment-factors-on-body-size-among-breast-cancer-survivors-the-pathways-study
#7
Salma Shariff-Marco, Julie Von Behren, Peggy Reynolds, Theresa H M Keegan, Andrew Hertz, Marilyn L Kwan, Janise M Roh, Catherine Thomsen, Candyce H Kroenke, Christine B Ambrosone, Lawrence H Kushi, Scarlett Lin Gomez
BACKGROUND: As social and built environment factors have been shown to be associated with physical activity, dietary patterns, and obesity in the general population, they likely also influence these health behaviors among cancer survivors, and thereby impact survivorship outcomes. METHODS: Enhancing the rich, individual-level survey and medical record data from 4,505 breast cancer survivors in the Pathways Study, a prospective cohort drawn from Kaiser Permanente Northern California, we geocoded baseline residential addresses and appended social and built environment data...
February 2, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28152151/population-attributable-risk-proportion-of-clinical-risk-factors-for-breast-cancer
#8
Natalie J Engmann, Marzieh K Golmakani, Diana L Miglioretti, Brian L Sprague, Karla Kerlikowske
Importance: Many established breast cancer risk factors are used in clinical risk prediction models, although the proportion of breast cancers explained by these factors is unknown. Objective: To determine the population-attributable risk proportion (PARP) for breast cancer associated with clinical breast cancer risk factors among premenopausal and postmenopausal women. Design, Setting, and Participants: Case-control study with 1:10 matching on age, year of risk factor assessment, and Breast Cancer Surveillance Consortium (BCSC) registry...
February 2, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28145413/stearoyl-coa-desaturase-1-a-novel-target-of-omega-3-fatty-acids-for-reducing-breast-cancer-risk-in-obese-postmenopausal-women
#9
A Manni, J P Richie, S E Schetter, A Calcagnotto, N Trushin, C Aliaga, K El-Bayoumy
BACKGROUND/OBJECTIVES: Conversion of saturated fatty acids to monounsaturated fatty acids by the enzyme stearoyl-Co-A-desaturase (SCD-1) is emerging as a major factor in promoting carcinogenesis including breast cancer. The aim of our study was to explore the regulation of SCD-1 by Raloxifene and omega-3 fatty acids in women at increased risk of breast cancer based on high breast density. SUBJECTS/METHODS: As a reflection of SCD-1 activity, we measured the ratios of palmitoleic acid (C16:1n7) to palmitic acid (C16:0) (SCD-16) and oleic acid (C18:1n9) to steric acid (C18:0) (SCD-18) in plasma samples of postmenopausal women enrolled in our clinical trial (NCT00723398) designed to test the effects of the antiestrogen, Raloxifene and/or the omega-3 preparation Lovaza, on breast density, a validated biomarker of breast cancer risk...
February 1, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28143431/mammographic-breast-density-and-risk-of-breast-cancer-in-women-with-atypical-hyperplasia-an-observational-cohort-study-from-the-mayo-clinic-benign-breast-disease-bbd-cohort
#10
Robert A Vierkant, Amy C Degnim, Derek C Radisky, Daniel W Visscher, Ethan P Heinzen, Ryan D Frank, Stacey J Winham, Marlene H Frost, Christopher G Scott, Matthew R Jensen, Karthik Ghosh, Armando Manduca, Kathleen R Brandt, Dana H Whaley, Lynn C Hartmann, Celine M Vachon
BACKGROUND: Atypical hyperplasia (AH) and mammographic breast density (MBD) are established risk factors for breast cancer (BC), but their joint contributions are not well understood. We examine associations of MBD and BC by histologic impression, including AH, in a subcohort of women from the Mayo Clinic Benign Breast Disease Cohort. METHODS: Women with a diagnosis of BBD and mammogram between 1985 and 2001 were eligible. Histologic impression was assessed via pathology review and coded as non-proliferative disease (NP), proliferative disease without atypia (PDWA) and AH...
January 31, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28142043/initiators-and-promoters-for-the-occurrence-of-screen-detected-breast-cancer-and-the-progression-to-clinically-detected-interval-breast-cancer
#11
Amy Ming-Fang Yen, Wendy Yi-Ying Wu, Laszlo Tabar, Stephen W Duffy, Robert A Smith, Hsiu-Hsi Chen
BACKGROUND: The risk factors responsible for breast cancer have been well documented, but the roles of risk factors as initiators, causing the occurrence of screen-detected breast cancer, or promoters, responsible for the progression of the screen-detected to the clinically-detected breast cancer, have been scarcely evaluated. METHODS: We used data from women in a cohort in Kopparberg (Dalarna), Sweden between 1977 and 2010. Conventional risk factors, breast density, and tumor-specific biomarkers are superimposed to the temporal course of the natural history of the disease...
November 28, 2016: Journal of Epidemiology
https://www.readbyqxmd.com/read/28132392/determinants-of-volumetric-breast-density-in-chilean-premenopausal-women
#12
Ana Pereira, Maria Luisa Garmendia, Ricardo Uauy, Paulina Neira, Sandra Lopez-Arana, Serghei Malkov, John Shepherd
PURPOSE: High mammographic breast density (BD) is a strong risk factor of breast cancer; however, little is known in women under 40 years of age. Recently, dual-energy X-ray Absorptiometry (DXA) has been developed as a low-dose method to measure BD in young populations. Thus, our aims were to describe BD in relation to risk factors in Chilean women under 40 years old and to explore the equivalence of DXA to mammography for the measurement of BD. METHODS: We selected 192 premenopausal Chilean female participants of the DERCAM study for whom we have anthropometric, sociodemographic, and gyneco-obstetric data...
April 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28126634/the-relationship-of-maternal-bone-density-with-nutritional-rickets-in-nigerian-children
#13
Jennifer Hsu, Philip R Fischer, John M Pettifor, Tom D Thacher
Factors that affect maternal bone mineral density may be related to the risk of nutritional rickets in their offspring. Our aim was to determine the relationship between maternal areal bone mineral density (aBMD) and rickets in Nigerian children. Using a case-control design, we measured forearm aBMD in 56 and 135 mothers of children with and without nutritional rickets, respectively. Active rickets was confirmed or excluded in all children radiographically. Using logistic regression, we assessed the association of maternal aBMD, adjusted for parity, pregnancy and lactation status, duration of most recent completed lactation, age of menarche, height, body mass index, and maternal age with nutritional rickets...
January 23, 2017: Bone
https://www.readbyqxmd.com/read/28106545/the-alterations-of-serum-fgf-21-levels-metabolic-and-body-composition-in-early-breast-cancer-patients-receiving-adjuvant-endocrine-therapy
#14
Murat Akyol, Ahmet Alacacioglu, Leyla Demir, Yuksel Kucukzeybek, Yasar Yildiz, Zehra Gumus, Mete Kara, Tarik Salman, Umut Varol, Halil Taskaynatan, Utku Oflazoglu, Vedat Bayoglu, Mustafa Oktay Tarhan
BACKGROUND: In early breast cancer patients, the effects of hormonal therapy (tamoxifen and aromatase inhibitors) on plasma fibroblast growth factor 21 (FGF-21), lipid levels and body composition have not yet been investigated. Therefore, we aimed to analyze the relationship between FGF-21 and body composition as well as the effects of tamoxifen and aromatase inhibitors on plasma lipid levels, FGF-21, and body composition. METHODS: A total of 72 patients were treated with either tamoxifen or aromatase inhibitors due to their menopausal status after adjuvant radiotherapy...
January 13, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28089627/the-relationship-between-tamoxifen-associated-nonalcoholic-fatty-liver-disease-and-the-prognosis-of-patients-with-early-stage-breast-cancer
#15
Meiying Yan, Jingxuan Wang, Qijia Xuan, Tieying Dong, Juan He, Qingyuan Zhang
PURPOSE: To investigate the relationship between tamoxifen-associated nonalcoholic fatty liver disease (NAFLD) and survival outcomes in patients with breast cancer. METHODS: Patients with early-stage invasive breast cancer after curative resection from January 2009 to June 2011 were selected. A total of 646 patients who were treated with tamoxifen were included. Patients diagnosed with NAFLD on ultrasonography were classified into the NAFLD and non-NAFLD groups...
December 24, 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28068940/early-life-socioeconomic-environment-and-mammographic-breast-density
#16
Parisa Tehranifar, Barbara A Cohn, Julie D Flom, Angeline Protacio, Piera Cirillo, L H Lumey, Karin B Michels, Mary Beth Terry
BACKGROUND: Early life social environment may influence breast cancer through shaping risk factors operating in early life, adolescence and adulthood, or may be associated with breast cancer risk independent of known risk factors. We investigated the associations between early life socioeconomic status (SES) and mammographic density, a strong risk factor for breast cancer, and the extent to which these associations were independent of risk factors across the lifecourse. METHODS: We used data from an adult follow-up study of two U...
January 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28062399/longitudinal-study-of-mammographic-density-measures-that-predict-breast-cancer-risk
#17
Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Julie A Simpson, Gianluca Severi, Christopher Evans, Robert J MacInnis, Graham G Giles, Carmel Apicella, John L Hopper
BACKGROUND: After adjusting for age and body mass index (BMI), mammographic measures - dense area (DA), percent dense area (PDA) and non-dense area (NDA) - are associated with breast cancer risk. Our aim was to use longitudinal data to estimate the extent to which these risk-predicting measures track over time. METHODS: We collected 4,320 mammograms (age range, 24-83 years) from 970 women in the Melbourne Collaborative Cohort Study and the Australian Breast Cancer Family Registry...
January 6, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28040694/risk-factors-that-increase-risk-of-estrogen-receptor-positive-and-negative-breast-cancer
#18
Karla Kerlikowske, Charlotte C Gard, Jeffrey A Tice, Elad Ziv, Steven R Cummings, Diana L Miglioretti
BACKGROUND: Risk factors may differentially influence development of estrogen receptor (ER)-positive vs -negative breast cancer. We examined associations with strong, prevalent risk factors by ER subtype. METHODS: Of 1 279 443 women age 35 to 74 years participating in the Breast Cancer Surveillance Consortium, 14 969 developed ER-positive and 3617 developed ER-negative invasive breast cancer. We calculated hazard ratios (HRs) using Cox regression and compared ER subtype hazard ratios at representative ages or by menopausal status using Wald tests...
May 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28026901/the-effect-of-exercise-on-body-composition-and-bone-mineral-density-in-breast-cancer-survivors-taking-aromatase-inhibitors
#19
Gwendolyn A Thomas, Brenda Cartmel, Maura Harrigan, Martha Fiellin, Scott Capozza, Yang Zhou, Elizabeth Ercolano, Cary P Gross, Dawn Hershman, Jennifer Ligibel, Kathryn Schmitz, Fang-Yong Li, Tara Sanft, Melinda L Irwin
OBJECTIVE: This study examined the effect of 12 months of aerobic and resistance exercise versus usual care on changes in body composition in postmenopausal breast cancer survivors taking aromatase inhibitors (AIs). METHODS: The Hormones and Physical Exercise study enrolled 121 breast cancer survivors and randomized them to either supervised twice-weekly resistance exercise training and 150 min/wk of aerobic exercise (N = 61) or a usual care (N = 60) group. Dual-energy X-ray absorptiometry scans were conducted at baseline, 6 months, and 12 months to assess changes in body mass index, percent body fat, lean body mass, and bone mineral density...
February 2017: Obesity
https://www.readbyqxmd.com/read/27986574/mammography-before-and-after-bariatric-surgery
#20
Tara E Mokhtari, Ulysses S Rosas, John R Downey, Kanae K Miyake, Debra M Ikeda, John M Morton
BACKGROUND: Morbidly obese women are at increased risk for breast cancer, and the majority of surgical weight-loss patients are older than 40 years old. OBJECTIVE: The purpose of the present study was to determine the technical and interpretive changes in mammography following bariatric surgery. SETTING: Accredited Academic Hospital. METHODS: Two breast-imaging radiologists reviewed screening mammograms performed on 10 morbidly obese women undergoing bariatric surgery both pre- and postoperatively...
October 31, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
keyword
keyword
32640
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"