keyword
MENU ▼
Read by QxMD icon Read
search

immunisations

keyword
https://www.readbyqxmd.com/read/28811050/vaccine-decision-making-begins-in-pregnancy-correlation-between-vaccine-concerns-intentions-and-maternal-vaccination-with-subsequent-childhood-vaccine-uptake
#1
M H Danchin, J Costa-Pinto, K Atwell, H Willaby, K Wiley, M Hoq, J Leask, K P Perrett, Jacinta O'Keefe, M L Giles, H Marshall
INTRODUCTION: Maternal and childhood vaccine decision-making begins prenatally. Amongst pregnant Australian women we aimed to ascertain vaccine information received, maternal immunisation uptake and attitudes and concerns regarding childhood vaccination. We also aimed to determine any correlation between a) intentions and concerns regarding childhood vaccination, (b) concerns about pregnancy vaccination, (c) socioeconomic status (SES) and (d) uptake of influenza and pertussis vaccines during pregnancy and routine vaccines during childhood...
August 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28810833/population-effectiveness-of-the-pentavalent-and-monovalent-rotavirus-vaccines-a-systematic-review-and-meta-analysis-of-observational-studies
#2
Daniel Hungerford, Katie Smith, Angela Tucker, Miren Iturriza-Gómara, Roberto Vivancos, Catherine McLeonard, Nigel A Cunliffe, Neil French
BACKGROUND: Rotavirus was the leading cause of acute gastroenteritis (AGE) in infants and young children prior to the introduction of routine vaccination. Since 2006 there have been two licensed vaccines available; with successful clinical trials leading the World Health Organization to recommend rotavirus vaccination for all children worldwide. In order to inform immunisation policy we have conducted a systematic review and meta-analysis of observation studies to assess population effectiveness against acute gastroenteritis...
August 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28808938/advances-in-vaccines-to-prevent-viral-respiratory-illnesses-in-children
#3
Aleisha J Anderson, Tom L Snelling, Hannah C Moore, Christopher C Blyth
Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens. Acute lower respiratory infection (ALRI) of both bacterial and viral aetiology continues to impact global child health. Key bacterial pathogens including Streptococcus pneumoniae and Haemophilus influenza type b are specifically targeted with current vaccination programmes, while at present there are less effective strategies for the prevention of viral disease...
August 14, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28807627/measles-immunity-gaps-and-the-progress-towards-elimination-a-multi-country-modelling-analysis
#4
Filippo Trentini, Piero Poletti, Stefano Merler, Alessia Melegaro
BACKGROUND: The persistent circulation of measles in both low-income and high-income countries requires a better characterisation of present epidemiological trends and existing immunity gaps across different sociodemographic settings. Serological surveys, which provide direct measures of population protection against the infection, are underexploited and often supply fragmentary estimates of population immunity. This study aims to investigate how measles immunity has changed over time across different socioeconomic settings, as a result of demographic changes and past immunisation policies...
August 11, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28804787/burden-of-paediatric-respiratory-syncytial-virus-disease-and-potential-effect-of-different-immunisation-strategies-a-modelling-and-cost-effectiveness-analysis-for-england
#5
Deborah Cromer, Albert Jan van Hoek, Anthony T Newall, Andrew J Pollard, Mark Jit
BACKGROUND: Vaccines and prophylactic antibodies against respiratory syncytial virus (RSV) are in development and likely to be available in the next 5-10 years. The most efficient way to use these products when they become available is an important consideration for public health decision makers. METHODS: We performed a multivariate regression analysis to estimate the burden of RSV in children younger than 5 years in England (UK), a representative high-income temperate country, and used these results to assess the potential effect of different RSV immunisation strategies (targeting vaccination for infants, or pregnant women, or prophylactic antibodies for neonates)...
August 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/28802754/cost-benefit-analyses-of-supplementary-measles-immunisation-in-the-highly-immunized-population-of-new-zealand
#6
D T S Hayman, J C Marshall, N P French, T E Carpenter, M G Roberts, T Kiedrzynski
As endemic measles is eliminated from countries through increased immunisation, the economic benefits of enhanced immunisation programs may come into question. New Zealand has suffered from outbreaks after measles introductions from abroad and we use it as a model system to understand the benefits of catch up immunisation in highly immunised populations. We provide cost-benefit analyses for measles supplementary immunisation in New Zealand. We model outbreaks based on estimates of the basic reproduction number in the vaccinated population (Rv, the number of secondary infections in a partially immunised population), based on the number of immunologically-naïve people at district and national levels, considering both pre- and post-catch up vaccination scenarios...
August 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28802753/challenges-in-immunisation-service-delivery-for-refugees-in-australia-a-health-system-perspective
#7
A Mahimbo, H Seale, M Smith, A Heywood
BACKGROUND: Refugees are at risk of being under-immunised in their countries of origin, in transit and post-resettlement in Australia. Whilst studies have focused on identifying barriers to accessibility of health services among refugees, few focus on providers' perspectives on immunisation service delivery to this group. Health service providers are well placed to provide insights into the pragmatic challenges associated with refugee health service delivery, which can be useful in identifying strategies aimed at improving immunisation coverage among this group...
August 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28801155/vaccinations-in-the-first-year-of-life-and-risk-of-atopic-disease-results-from-the-kiggs-study
#8
Martin Schlaud, Roma Schmitz, Christina Poethko-Müller, Ronny Kuhnert
BACKGROUND: The study focused on the question of whether and - if so - to what direction and extent immunisations in the 1st year may be associated with the risk of being diagnosed with atopic diseases after the 1st year of life. METHODS: Data from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS, 2003-2006) were analysed. For analyses of potential associations between vaccination status and risk of hay fever, atopic dermatitis or asthma, sample sizes of 15254, 14297, and 15262, respectively, were available...
August 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28799083/vaccination-coverage-and-mortality-after-splenectomy-results-from-an-italian-single-centre-study
#9
Antonio Di Sabatino, Marco Vincenzo Lenti, Francesco Paolo Tinozzi, Marina Lanave, Ivana Aquino, Catherine Klersy, Piero Marone, Carlo Marena, Andrea Pietrabissa, Gino Roberto Corazza
Splenectomy is a well-recognised risk factor for life-threatening overwhelming post-splenectomy infection (OPSI). To prevent OPSI, immunisations against encapsulated bacteria (S. pneumoniae, N. meningitidis, H. influenzae) and influenza virus are recommended. However, there is still a lack of uniformity and poor compliance with these recommendations. Following a local physicians' awareness campaign regarding the importance of vaccine prophylaxis of splenectomised patients, we aimed to register vaccination coverage, mortality and infection rates in all patients who underwent splenectomy at our hospital, over a six-year time span...
August 10, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28797124/preclinical-development-of-a-vaccine-against-oligomeric-alpha-synuclein-based-on-virus-like-particles
#10
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H M Hunn, Nora Bengoa-Vergniory, Milena Cioroch, Mauricio Ramm, Amy M Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F Bachmann
Parkinson's disease (PD) is a progressive and currently incurable neurological disorder characterised by the loss of midbrain dopaminergic neurons and the accumulation of aggregated alpha-synuclein (a-syn). Oligomeric a-syn is proposed to play a central role in spreading protein aggregation in the brain with associated cellular toxicity contributing to a progressive neurological decline. For this reason, a-syn oligomers have attracted interest as therapeutic targets for neurodegenerative conditions such as PD and other alpha-synucleinopathies...
2017: PloS One
https://www.readbyqxmd.com/read/28795455/perceptions-of-caregivers-and-providers-regarding-the-potential-introduction-of-the-varicella-vaccine-to-the-childhood-immunisation-schedule-in-new-zealand-a-qualitative-exploratory-study
#11
Nadia A Charania, Donna G Watson, Nikki M Turner
AIM: The varicella vaccine has been proposed to be added to the childhood immunisation schedule in New Zealand as the fourth injectable at the 15-month event. We sought to understand the perceptions of caregivers and health-care providers regarding the potential introduction of routine varicella vaccination. METHODS: A qualitative exploratory study was conducted using semi-structured interviews with caregivers and providers (N = 20) in Auckland. Key themes from the interviews were identified through thematic analysis using a combination of deductive and inductive coding...
August 9, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28794096/an-increase-in-accident-and-emergency-presentations-for-adverse-events-following-immunisation-after-introduction-of-the-group-b-meningococcal-vaccine-an-observational-study
#12
Viveka Nainani, Ushma Galal, Jim Buttery, Matthew D Snape
OBJECTIVES: To determine whether the introduction of the capsular group B meningococcal vaccine (4CMenB) in the UK has increased presentations of infants to emergency departments with adverse events following immunisation (AEFI). PARTICIPANTS, DESIGN AND SETTING: A retrospective review of hospital records of infants aged 1-6 months presenting to Oxford University Hospitals NHS Trust's emergency departments from September 2013 to August 2016 with discharge diagnoses of vaccine reactions or non-specific conditions...
August 9, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28792332/meningitis-and-septicaemia-vaccinations
#13
Kimberley Hackett
Essential facts Teenagers and young people are the second most at-risk group for contracting meningitis and septicaemia. Due to an increase in the virulent strain of meningitis MenW, the Joint Committee on Vaccination and Immunisation has recommended a programme to vaccinate all people aged 14 to 18 years.
August 9, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28782441/connecting-remote-populations-to-public-health-the-case-for-a-digital-immunisation-information-system-in-nunavut
#14
Lindsay A Wilson, Barry Pakes, Malia S Q Murphy, Katherine M Atkinson, Cameron Bell, Kumanan Wilson
Despite the best efforts of local healthcare workers and health officials, Nunavut, a large geographical region in Northern Canada, has struggled with outbreaks of vaccine-preventable diseases (VPD). We contend that the implementation of an immunisation information system (IIS) could strengthen prevention and response efforts to this and future outbreaks of vaccine-preventable diseases. Developing an IIS in Nunavut that builds on the existing CANImmunize infrastructure would reduce the cost and complexity of developing a new IIS, and allow Nunavut to benefit from the ongoing efforts to secure data on the CANImmunize platform...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28776206/healthcare-associated-clostridium-difficile-infections-are-sustained-by-disease-from-the-community
#15
Angus McLure, Archie C A Clements, Martyn Kirk, Kathryn Glass
Clostridium difficile infections (CDIs) are some of the most common hospital-associated infections worldwide. Approximately 5% of the general population is colonised with the pathogen, but most are protected from disease by normal intestinal flora or immune responses to toxins. We developed a stochastic compartmental model of CDI in hospitals that captures the condition of the host's gut flora and the role of adaptive immune responses. A novel, derivative-based method for sensitivity analysis of individual-level outcomes was developed and applied to the model...
August 3, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28775292/mucosal-vaccination-with-pili-from-group-a-streptococcus-expressed-on-lactococcus-lactis-generates-protective-immune-responses
#16
Jacelyn M S Loh, Natalie Lorenz, Catherine J-Y Tsai, Adrina Hema J Khemlani, Thomas Proft
The human pathogen Group A Streptococcus (GAS) produces pili that are involved in adhesion and colonisation of the host. These surface-exposed pili are immunogenic and therefore represent an attractive target for vaccine development. The pilus is encoded in the genomic region known as the fibronectin-collagen-T-antigen (FCT)-region, of which at least nine different types have been identified. In this study we investigate expressing two of the most common FCT-types (FCT-3 and FCT-4) in the food-grade bacteria Lactococcus lactis for use as a mucosal vaccine...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28774566/correlation-between-anthrax-lethal-toxin-neutralizing-antibody-levels-and-survival-in-guinea-pigs-and-nonhuman-primates-vaccinated-with-the-av7909-anthrax-vaccine-candidate
#17
Vladimir Savransky, Jeffry D Shearer, Melicia R Gainey, Daniel C Sanford, Gloria S Sivko, Gregory V Stark, Na Li, Boris Ionin, Michael J Lacy, Mario H Skiadopoulos
The anthrax vaccine candidate AV7909 is being developed as a next generation vaccine for a post-exposure prophylaxis (PEP) indication against anthrax. AV7909 consists of the Anthrax Vaccine Adsorbed (AVA, BioThrax®) bulk drug substance adjuvanted with the immunostimulatory oligodeoxynucleotide (ODN) compound, CPG 7909. The addition of CPG 7909 to AVA enhances both the magnitude and the kinetics of antibody responses in animals and human subjects, making AV7909 a suitable next-generation vaccine for use in a PEP setting...
July 31, 2017: Vaccine
https://www.readbyqxmd.com/read/28770639/the-preventive-effects-of-nanopowdered-red-ginseng-on-collagen-induced-arthritic-mice
#18
Yun-Kyung Lee, Kyung-Hoon Choi, Hae-Soo Kwak, Yoon Hyuk Chang
This study was carried out to investigate the efficiency of red ginseng nanopowder in preventing collagen-induced arthritis (CIA) in mice. The mice were divided into five groups: normal group (no immunisation), control (CIA), powdered red ginseng (PRG), nanopowdered red ginseng (NRG) and methotrexate (MTX). Administering MTX, PRG and NRG to arthritic mice significantly decreased spleen indexes, clinical and histological scores compared to control group. Serum analysis of NRG and MTX groups showed a reduction in the cytokines such as the levels of tumour necrosis factor alpha (TNF-α), interleukin 6 (IL-6) and interleukin 1β (IL-1β) in comparison to PRG group...
August 3, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28764768/more-than-a-virus-a-qualitative-study-of-the-social-implications-of-hepatitis-b-infection-in-china
#19
J Wallace, M Pitts, C Liu, V Lin, B Hajarizadeh, J Richmond, S Locarnini
BACKGROUND: China has the largest absolute number of people living with hepatitis B with up to 300,000 people estimated to die each year from hepatitis B related diseases. Despite advances in immunisation, clinical management, and health policy, there is still a lack of accessible and affordable health care for people with hepatitis B. Through in-depth interviews, this study identifies the personal, social and economic impact of living with hepatitis B and considers the role of stigma and discrimination as barriers to effective clinical management of the disease...
August 1, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28761614/-impact-of-controlled-temperature-chain-ctc-approach-on-immunization-coverage-achieved-during-the-preventive-vaccination-campaign-against-meningitis-a-using-menafrivac-in-togo-in-2014
#20
Dadja Essoya Landoh, Anna-Léa Kahn, Anani Lacle, Kodjovi Adjeoda, Bayaki Saka, Issifou Yaya, Danladi Ibrahim Nassoury, Assima Kalao, Makawa-Sy Makawa, Nsiari-Mueyi Joseph Biey, Andre Bita, Yaovi Temfa Toke, Petit Dörte, Lucile Imboua, Olivier Ronveaux
METHOD: We conducted a survey from 9 to 14 March 2015 (for approximately 3 months) after the end of the vaccination campaign in these four regions. Interviewees were selected using two stages cluster sampling stratified according to the regions. MenAfriVac vaccine in Controlled Temperature Chain (CTC) was used in 10 districts, in Togo. RESULTS: A total of 2707 households were surveyed and 9082 people aged 1-29 years were interviewed. The average age of the individuals surveyed was 11...
2017: Pan African Medical Journal
keyword
keyword
32632
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"