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https://www.readbyqxmd.com/read/28426381/hyperbaric-oxygen-for-experimental-intracerebral-haemorrhage-systematic-review-and-stratified-meta-analysis
#1
Han-Jin Cui, Hao-Yu He, A-Li Yang, Hua-Jun Zhou, Tao Tang, Jie-Kun Luo
OBJECTIVE: Hyperbaric oxygen (HBO) is widely used in treating various neurological diseases. However, HBO for treatment of intracerebral haemorrhage (ICH) remains controversial, in either animal or clinical studies. Therefore, we conducted this systematic review and meta-analysis on studies describing the efficacy of HBO in animal models of ICH. METHODS: Studies were identified by searching mainstream databases through November 2015. The efficacy of HBO in animal models of ICH was assessed by changes in the brain water content (BWC), neurobehavioural outcome (NO) or both...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28413648/effects-of-hyperbaric-oxygen-treatment-on-gastric-cancer-cell-line-sgc7901
#2
Yinliang Qi, Jianfeng Ruan, Mei Wang, Yuanchang Dai, Qing Zhou, Shuyu Gui, Sumei Zhang, Yuan Wang
Hyperbaric oxygen (HBO) has been previously identified as an effective adjunct treatment option for the management of brain injury, diabetic ulcers and chronic wounds. However, the roles of HBO as an adjunctive therapy for tumors remain controversial. The present research project was performed to explore the effects of HBO treatment on proliferation, autophagy and endoplasmic reticulum stress response of the gastric cancer cell line, SGC7901. The present study demonstrated that, after subjecting SGC7901 cells to HBO treatment, the increase in cell proliferation was significant, compared with that of the control group...
April 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28410116/hyperbaric-oxygenation-for-resuscitation-and-therapy-of-elderly-patients-with-cerebral-and-cardio-respiratory-dysfunction
#3
Gennady G Rogatsky, Ilia Stambler
Hyperbaric oxygenation therapy (HBOT) has been gaining an increasing recognition as a versatile therapeutic approach. This article reviews the application of hyperbaric oxygenation as a method for resuscitation and therapy of elderly patients with cerebral and cardio-respiratory dysfunction, in acute as compared to chronic impairments. The vital role of proper dosage of HBO therapy to ensure both the efficacy and safety of the treatment is emphasized. We argue that in the acute stages of brain and cardiorespiratory impairment, the adequate hyperbaric oxygen dose is the most important condition for obtaining maximum therapeutic effect, due to the powerful anti-hypoxic capabilities of this method...
June 1, 2017: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/28393184/hyperbaric-oxygen-inhibits-venous-neointimal-hyperplasia-following-arteriovenous-fistulization
#4
Zhui Li, Maoping Li, Xiangjie Li, Mao Zhang, Yu Zhao, Wei Ren, Jun Cheng, Xuehu Wang
Hypoxia following arteriovenous fistulization results in venous neointimal hyperplasia (VNH), potentially causing early arteriovenous fistula (AVF) dysfunction. In this study, we used hyperbaric oxygen (HBO) in a rabbit model of AVF to determine whether it could ameliorate early AVF failure. Chronic renal failure was induced by adenine in 96 adult rabbits randomly divided into 3 groups (n=32 in each group). The sham + HBO group underwent sham operation and received HBO. The AVF alone group underwent fistulization, but did not receive HBO...
April 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28385082/hyperbaric-oxygen-therapy-modulates-serum-opg-rankl-in-femoral-head-necrosis-patients
#5
Giuliano Vezzani, Silvia Quartesan, Pasqua Cancellara, Enrico Camporesi, Devanand Mangar, Thomas Bernasek, Prachiti Dalvi, Zhongjin Yang, Antonio Paoli, Alex Rizzato, Gerardo Bosco
Hyperbaric oxygen therapy (HBOT) has beneficial effects on avascular necrosis of femoral head (ANFH), but its mechanism of action is still unclear. We investigated if HBOT upregulates serum osteoprotegerin (OPG) and/or inhibits osteoclast activation. 23 patients with unilateral ANFH at stage I, II and III consented to the study: the patients received standard HBOT. Serum OPG levels were obtained at the beginning of HBOT (T0), after 15 sessions (T1), 30 sessions (T2), after a 30-day break (T3), and after 60 sessions (T4)...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28378582/low-affinity-zinc-sensor-showing-fluorescence-responses-with-minimal-artifacts
#6
Xinhao Yan, Jin Ju Kim, Hye Sun Jeong, Yu Kyung Moon, Yoon Kyung Cho, Soyeon Ahn, Sang Beom Jun, Hakwon Kim, Youngmin You
The study of the zinc biology requires molecular probes with proper zinc affinity. We developed a low-affinity zinc probe (HBO-ACR) based on an azacrown ether (ACR) and an 2-(2-hydroxyphenyl)benzoxazole (HBO) fluorophore. This probe design imposed positive charge in the vicinity of a zinc coordination center, which enabled fluorescence turn-on responses to high levels of zinc without being affected by the pH and the presence of other transition-metal ions. Steady-state and transient photophysical investigations suggested that such a high tolerance benefits from orchestrated actions of proton-induced nonradiative and zinc-induced radiative control...
April 5, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28374694/-dynamics-of-eeg-and-psychophysiological-indicators-of-acute-poisoning-neurotoxicants-on-the-stage-of-rehabilitation-on-the-background-of-different-methods-of-treatment
#7
I Yu Berezina, A V Badalyan, L I Sumsky, Yu S Gol'dfarb
AIM: To evaluate the dynamics of functional activity of brain structures underlying cognitive functions in patients with encephalopathy due to poisoning with neurotoxicants on the stage of rehabilitation. MATERIAL AND METHODS: Fifty-six patients were examined. The main group consisted of 40 patients treated with intravenous injections with mexidol (n=10), combination of mexidol with non-pharmacological methods - mesodiencephalic modulation (MDM) (n=10), hyperbaric oxygenation (HBO) (n=10) and the combination of MDM and HBO (n=10)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28362819/hydrogen-gas-alleviates-oxygen-toxicity-by-reducing-hydroxyl-radical-levels-in-pc12-cells
#8
Junchao Yu, Qiuhong Yu, Yaling Liu, Ruiyun Zhang, Lianbi Xue
Hyperbaric oxygen (HBO) therapy through breathing oxygen at the pressure of above 1 atmosphere absolute (ATA) is useful for varieties of clinical conditions, especially hypoxic-ischemic diseases. Because of generation of reactive oxygen species (ROS), breathing oxygen gas at high pressures can cause oxygen toxicity in the central nervous system, leading to multiple neurological dysfunction, which limits the use of HBO therapy. Studies have shown that Hydrogen gas (H2) can diminish oxidative stress and effectively reduce active ROS associated with diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28352069/efficacy-of-n-butylphthalide-and-hyperbaric-oxygen-therapy-on-cognitive-dysfunction-in-patients-with-delayed-encephalopathy-after-acute-carbon-monoxide-poisoning
#9
RANDOMIZED CONTROLLED TRIAL
Wenping Xiang, Hui Xue, Baojun Wang, Yuechun Li, Jun Zhang, Changchun Jiang, Jiangxia Pang
BACKGROUND Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) is one of the most serious complications after CO poisoning. This study was conducted to explore the efficacy of the combined application of N-Butylphthalide and hyperbaric oxygenation therapy (HBO) on cognitive dysfunction in patients with DEACMP. MATERIAL AND METHODS A total of 184 patients with DEACMP were randomly assigned to either receive HBO or N-Butylphthalide and HBO. Meanwhile, all patients received conventional treatment...
March 29, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28336821/hyperbaric-oxygen-therapy-reduces-renal-lactate-production
#10
Thomas S Nørlinger, Per Mose Nielsen, Haiyun Qi, Emmeli Mikkelsen, Kasper Hansen, Nikolaj H Schmidt, Michael Pedersen, Peter Agger, Fredrik Palm, Christoffer Laustsen
Intrarenal hypoxia is an acknowledged factor contributing to the development of diabetic nephropathy. Hyperbaric oxygen (HBO) therapy is a well-known adjuvant treatment for several medical conditions, such as decompression sickness, infections, and wound healing. The underlying metabolic response of HBO is largely unknown. In this study, we investigated the effect of HBO on the intrarenal metabolic alteration in diabetes. Hyperpolarized [1-(13)C]pyruvate MRI was performed to assess intrarenal energy metabolism in normoglycemic controls and short-term (2 weeks) streptozotocin-induced diabetic rats with and without HBO for five consecutive days...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28336339/optimal-feature-selection-from-fnirs-signals-using-genetic-algorithms-for-bci
#11
Farzan Majeed Noori, Noman Naseer, Nauman Khalid Qureshi, Hammad Nazeer, Rayyan Azam Khan
In this paper, a novel technique for determination of the optimal feature combinations and, thereby, acquisition of the maximum classification performance for a functional near-infrared spectroscopy (fNIRS)-based brain-computer interface (BCI), is proposed. After obtaining motor-imagery and rest signals from the motor cortex, filtering is applied to remove the physiological noises. Six features (signal slope, signal mean, signal variance, signal peak, signal kurtosis and signal skewness) are then extracted from the oxygenated hemoglobin (HbO)...
March 20, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28328661/microangiography-to-monitor-treatment-outcomes-following-severe-frostbite-injury-to-the-hands
#12
Thomas Masters, Steven Omodt, Jon Gayken, Christopher Logue, Bjorn Westgard, Stephen Hendriksen, Joseph Walter, Rachel Nygaard
Frostbite injury causes direct damage to tissues following exposure to temperatures below their freezing point causing tissue death potentially leading to serious amputations. After rewarming, a variety of treatment options have been employed to avoid amputation. This case report details the use of indocyanine green fluorescence microangiography to monitor the clinical progression of perfusion following hyperbaric oxygen therapy (HBOT) for severe frostbite injury. We present a case report of a man with deep frostbite of the bilateral hands treated with thrombolytics and HBOT...
March 15, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28325788/decompression-illness-with-hypovolemic-shock-and-neurological-failure-symptoms-after-two-risky-dives-a-case-report
#13
Sebastian Klapa, Johannes Meyne, Wataru Kähler, Frauke Tillmans, Henning Werr, Andreas Binder, Andreas Koch
Hypovolemia is known to be a predisposing factor of decompression illness (DCI) while diving. The typical clinically impressive neurological symptoms of DCI may distract from other symptoms such as an incipient hypovolemic shock. We report the case of a 61-year-old male Caucasian, who presented with an increasing central and peripheral neural failure syndrome and massive hypovolemia after two risky dives. Computed tomography (CT) scans of the chest and Magnetic resonance imaging scans of the head revealed multiple cerebral and pulmonary thromboembolisms...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28267944/changes-in-cerebral-oxygen-saturation-and-haemoglobin-concentration-during-paediatric-cardiac-surgery
#14
T Suemori, S B Horton, S Bottrell, J J Skowno, A Davidson
Although near-infrared spectroscopy (NIRS) enables bedside assessment of cerebral oxygenation, it provides little information on the cause of deoxygenation. The authors aimed to investigate the changes in cerebral oxygenation and haemoglobin concentration and their associations during paediatric cardiac surgery in order to elucidate the physiology underlying cerebral deoxygenation. An observational retrospective study on 399 patients who underwent paediatric cardiac surgery was conducted. With use of NIRS, cerebral oxygen saturation as expressed by tissue oxygen index (TOI) before and after surgery, concentration changes in oxygenated haemoglobin (Δ[HbO<sub>2</sub>]) and deoxygenated haemoglobin (Δ[HHb]) after surgery were studied as were the associations between these values and clinical variables...
March 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28260864/combined-application-of-dexamethasone-and-hyperbaric-oxygen-therapy-yields-better-efficacy-for-patients-with-delayed-encephalopathy-after-acute-carbon-monoxide-poisoning
#15
Wenping Xiang, Hui Xue, Baojun Wang, Yuechun Li, Jun Zhang, Changchun Jiang, Furu Liang, Jiangxia Pang, Lehua Yu
BACKGROUND: Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) commonly occurs after recovering from acute CO poisoning. This study was performed to assess the efficacy of the combined application of dexamethasone and hyperbaric oxygen (HBO) therapy in patients with DEACMP. PATIENTS AND METHODS: A total of 120 patients with DEACMP were recruited and randomly assigned into the experimental group (receiving dexamethasone 5 mg/day or 10 mg/day plus HBO therapy) and control group (HBO therapy as monotherapy)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28225493/acetylcholinesterase-inhibitor-treatment-alleviated-cognitive-impairment-caused-by-delayed-encephalopathy-due-to-carbon-monoxide-poisoning-two-case-reports-and-a-review-of-the-literature
#16
REVIEW
Kumi Yanagiha, Kazuhiro Ishii, Akira Tamaoka
INTRODUCTION: Delayed encephalopathy due to carbon monoxide (CO) poisoning can even occur in patients with mild symptoms of acute CO poisoning. Some cases taking conventional hyperbaric oxygen (HBO) therapy or steroid-pulse therapy may be insufficient, and AchEI may be effective. PATIENT CONCERNS AND DIAGNOSES: We report two cases of delayed encephalopathy after acute CO poisoning involving two women aged 69 (Case 1) and 60 years (Case 2) whose cognitive function improved with acetylcholinesterase inhibitor (AchEI) treatment...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28217297/hyperbaric-oxygen-therapy-and-preconditioning-for-ischemic-and-hemorrhagic-stroke
#17
REVIEW
Sheng-Li Hu, Hua Feng, Guo-Hua Xi
To date, the therapeutic methods for ischemic and hemorrhagic stroke are still limited. The lack of oxygen supply is critical for brain injury following stroke. Hyperbaric oxygen (HBO), an approach through a process in which patients breathe in 100% pure oxygen at over 101 kPa, has been shown to facilitate oxygen delivery and increase oxygen supply. Hence, HBO possesses the potentials to produce beneficial effects on stroke. Actually, accumulated basic and clinical evidences have demonstrated that HBO therapy and preconditioning could induce neuroprotective functions via different mechanisms...
October 2016: Medical Gas Research
https://www.readbyqxmd.com/read/28217293/application-of-hyperbaric-oxygen-in-liver-transplantation
#18
REVIEW
Hu Lv, Cui-Hong Han, Xue-Jun Sun, Wen-Wu Liu
In recent years, hyperbaric oxygen (HBO) has been used in the treatment of a lot of diseases such as decompression sickness, arterial gas embolism, carbon dioxide poisoning, soft tissue infection, refractory osteomyelitis, and problematic wound, but little is known about its application in liver transplantation. Although several studies have been conducted to investigate the protective effects of HBO on liver transplantation and liver preservation, there are still some controversies on this issue, especially its immunomodulatory effect...
October 2016: Medical Gas Research
https://www.readbyqxmd.com/read/28217290/neuroprotective-effect-of-hyperbaric-oxygen-therapy-in-a-juvenile-rat-model-of-repetitive-mild-traumatic-brain-injury
#19
Lei Huang, Andre Obenaus, Mary Hamer, John H Zhang
Repetitive mild traumatic brain injury (rmTBI) is an important medical concern for adolescent athletes that can lead to long-term disabilities. Multiple mild injuries may exacerbate tissue damage resulting in cumulative brain injury and poor functional recovery. In the present study, we investigated the increased brain vulnerability to rmTBI and the effect of hyperbaric oxygen treatment using a juvenile rat model of rmTBI. Two episodes of mild cortical controlled impact (3 days apart) were induced in juvenile rats...
October 2016: Medical Gas Research
https://www.readbyqxmd.com/read/28215388/impact-of-weight-of-the-nation-community-screenings-on-obesity-related-beliefs
#20
Courtney T Luecking, Seth M Noar, Rachel M Dooley, Ziya Gizlice, Alice S Ammerman
INTRODUCTION: HBO's Weight of the Nation was a collaborative effort among several national organizations to raise awareness about the complexity of the obesity epidemic and promote action through media and community forums. The primary aim of this study was to assess the short-term effects of Weight of the Nation community screenings on obesity-related beliefs, intentions, and policy support. METHODS: Five Prevention Research Centers across the U.S. administered surveys at nine Weight of the Nation community screenings between September 2012 and May 2013...
March 2017: American Journal of Preventive Medicine
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