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https://www.readbyqxmd.com/read/28810963/treating-decompression-sickness-military-flight-simulation-site-community-hospital-partnership
#1
Whitney C Rhodes, George Hertner, Robert Price, Lani Finck, Claudia Temmer, Tracy Cushing, Kathleen Flarity
BACKGROUND: High-altitude flight simulation familiarizes military trainees with the symptoms of hypoxia to prepare them for emergency situations. Decompression sickness (DCS) can occur as a result of these simulations. In cases when ground-level supplemental oxygen does not resolve symptoms, hyperbaric oxygen (HBO) therapy is indicated. Many military hyperbaric chambers have been closed because of cost reductions, necessitating partnerships with community hospitals to ensure access to treatment...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28790369/arginyl-dipeptides-increase-the-frequency-of-nacl-elicited-responses-via-epithelial-sodium-channel-alpha-and-delta-subunits-in-cultured-human-fungiform-taste-papillae-cells
#2
Jiao-Jiao Xu, Nadia Elkaddi, Alvaro Garcia-Blanco, Andrew I Spielman, Alexander A Bachmanov, Hau Yin Chung, Mehmet Hakan Ozdener
Salty taste is one of the five basic tastes and is often elicited by NaCl. Because excess sodium intake is associated with many health problems, it could be useful to have salt taste enhancers that are not sodium based. In this study, the regulation of NaCl-induced responses was investigated in cultured human fungiform taste papillae (HBO) cells with five arginyl dipeptides: Ala-Arg (AR), Arg-Ala (RA), Arg-Pro (RP), Arg-Glu (RE), and Glu-Arg (ER); and two non-arginyl dipeptides: Asp-Asp (DD) and Glu-Asp (ED)...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28783893/delayed-treatment-of-frostbite-with-hyperbaric-oxygen-a-report-of-two-cases
#3
Corine A Lansdorp, Gert R Roukema, Onno Boonstra, Jan Dokter
Frostbite is an injury caused by the freezing of tissue, causing varied levels of tissue damage and necrosis. Case reports have shown a positive effect of hyperbaric oxygen (HBO₂) in such injuries, in acute cases as well as delayed (up to 21 days) presentation with complications. In this case report we present the course of hyperbaric treatment of two patients (a brother and sister, age 58 and 62) who sustained frostbite injuries to both feet 28 days earlier while hiking in the Himalayas. They were initially treated in Nepal following local protocol; afterward their primary care in the Netherlands was managed by the Burn Centre at Maasstad Hospital in Rotterdam...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783892/effect-of-hyperbaric-oxygen-therapy-on-complete-blood-count
#4
Ali Erdal Gunes, Samil Aktas
Complete blood count (CBC) is a routine diagnostic procedure for patients and a part of routine health inspection for healthy individuals. The effect of hyperbaric oxygen (HBO₂) on CBC is not known. The objective of this study was to determine the effects of HBO₂ on blood parameters in CBC with long-term HBO₂ therapy. In this study, patients received HBO₂ at the department of Underwater and Hyperbaric Clinical Medicine. CBC results were obtained at specific time points during HBO₂ therapy. The study recruited a total of 140 patients who met the research inclusion criteria...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783891/hyperbaric-oxygen-therapy-for-five-days-increases-blood-brain-barrier-permeability
#5
Selçuk Tatar, Nurcan Orhan, Canan Ugur Yilmaz, Nadir Arican, Bulent Ahishali, Mutlu Kucuk, Imdat Elmas, Mehmet Kaya, Akin Savas Toklu
This study aimed to explore the effects of hyperbaric oxygen (HBO₂) on blood-brain barrier (BBB) integrity in rats, when administered for one (at 2.5 ATA, 3 HBO₂ sessions a day) and five days (at 2.5 ATA, 3 HBO₂ sessions a day for the first two days, and twice a day for the last three days). Horseradish peroxidase (HRP) was used to evaluate the BBB permeability. Superoxide dismutase (SOD) activity, glutathione (GSH) and malondialdehyde (MDA) levels were measured in the cerebral cortex and hippocampus regions...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783890/reduction-of-side-effects-of-hyperbaric-oxygen-therapy-with-thymoquinone-treatment-in-rats
#6
Ali Erdal Gunes, Orhan Gozeneli, Muhammed Emin Guldur
INTRODUCTION: Hyperbaric oxygen (HBO₂) treatment results in elevated production of reactive oxygen species (ROS) that leads to cellular damage. Thymoquinone (TQ) is reported to have anti-inflammatory and antimicrobial activity and may suppress the generation of free radicals. The goal of this study is reduction of side effects of hyperbaric oxygen therapy with thymoquinone treatment. METHODS: 30 female Sprague-Dawley rats were randomly assigned to one of three groups (n = 10 per group)...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783888/attenuation-of-collagen-induced-arthritis-by-hyperbaric-oxygen-therapy-through-altering-immune-balance-in-favor-of-regulatory-t-cells
#7
Byung-In Moon, Hyung-Ran Kim, Eun-Jeong Choi, Jeong-Hae Kie, Ju-Young Seoh
Hyperbaric oxygen (HBO₂) therapy is currently used for the treatment of chronic wounds, radiation-induced soft tissue necrosis, several oxygen-deficiency conditions and decompression sickness. In addition to the current indications, much empirical and experimental data suggest that HBO₂ therapy may benefit autoimmune diseases by suppressing immunity, but the underlying mechanism is not well understood. Therefore, in the present study, we investigated whether HBO₂ prevents the development of collagen-induced arthritis (CIA) in association with alteration of the immune balance between pro-inflammatory Th17 and anti-inflammatory regulatory T cells (Tregs)...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783887/hyperbaric-oxygen-therapy-for-wound-breakdown-after-oronasal-fistula-and-cleft-palate-repair-four-cases
#8
C Lane Anzalone, Cara C Cockerill, Shelagh A Cofer
We offer the first report of hyperbaric oxygen (HBO₂) therapy to treat early surgical wound breakdown after oronasal fistula and cleft palate repair in the pediatric population. We present four patients' experiences after undergoing HBO₂ therapy. HBO₂ was initiated as soon as an oronasal fistula was identified. Three of the children underwent 10 HBO₂ treatments with the fourth undergoing 11 treatments. There were no adverse effects during treatment; none of the patients required decompressive myringotomy...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777909/cave-canem-hbo%C3%A2-therapy-efficacy-on-capnocytophaga-canimorsus-infections-a-case-series
#9
Mariano Marmo, Romolo Villani, Raffaele Maria Di Minno, Giuseppe Noschese, Matteo Paganini, Silvia Quartesan, Alex Rizzato, Gerardo Bosco
BACKGROUND: Dog bites are a frequent injury, but the incidence and type of lesions vary across countries. Although only few patients develop complications, the treatment of advanced injuries has a considerable medical, social and economic impact. A frequently isolated pathogen in dog bite wounds is Capnocytophaga canimorsus, a bacterium that can cause sepsis or meningitis. Hyperbaric oxygen (HBO₂) therapy has been shown to be useful in treating anaerobic infections, most likely because it creates an inhospitable environment for the bacterium and enhances the patient's immune response...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777908/carboxyhemoglobin-half-life-during-hyperbaric-oxygen-in-a-patient-with-lung-dysfunction-a-case-report
#10
Lindell K Weaver, Kayla Deru
INTRODUCTION: The carboxyhemoglobin half-life (COHb t1/2) during hyperbaric oxygen (HBO₂) is often quoted as 23 minutes, derived from the average of two adult male volunteers breathing HBO₂ at 3 atmospheres absolute (ATA). However, the mean COHb t1/2 of 12 male volunteer smokers was 26.3 minutes at 1.58 ATA and in 12 non-intubated carbon monoxide (CO) poisoned patients treated at 3 ATA, was 43 minutes. CASE REPORT: An 81-year old male, poisoned by an improperly ventilated natural gas heater, was intubated for coma, then treated with HBO₂...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777907/elimination-of-ct-detected-gas-bubbles-derived-from-decompression-illness-with-abdominal-symptoms-after-a-short-hyperbaric-oxygen-treatment-in-a-monoplace-chamber-a-case-report
#11
Takuya Oyaizu, Mitsuhiro Enomoto, Toshihide Tsujimoto, Yasushi Kojima, Atsushi Okawa, Kazuyoshi Yagishita
We report the case of a 54-year-old male compressed-air worker with gas bubbles detected by computed tomography (CT). He had complained of strong abdominal pain 30 minutes after decompression after working at a pressure equivalent to 17 meters of sea water for three hours. The initial CT images revealed gas bubbles in the intrahepatic portal vein, pulmonary artery and bilateral femoral vein. After the first hyperbaric oxygen treatment (HBO₂ at 2.5 atmospheres absolute/ATA for 150 minutes), no bubbles were detected on repeat CT examination...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777902/effects-of-hyperbaric-oxygen-on-hippocampal-neuronal-apoptosis-in-rats-with-acute-carbon-monoxide-poisoning
#12
Li Xue, Wen-Lan Wang, Ya Li, Xu Gong, Jun-Xiang Bao, Hai-Jun Zhang, Xiao-Ping Xie, Yao-Ming Chang, Jin-Sheng Li
INTRODUCTION: Acute carbon monoxide (CO) poisoning causes serious health problems such as neuropsychological sequelae. This study aimed to investigate neuronal apoptosis and the effects of hyperbaric oxygen (HBO₂) on different regions of the rat hippocampus after CO poisoning. METHODS: 90 mature male Sprague Dawley rats were randomly divided into three groups: the normal control group (NC group), the acute carbon monoxide-poisoned group (CO group) and the hyperbaric oxygen treatment group (HBO₂ group)...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777899/effect-of-hyperbaric-oxygen-therapy-on-blood-pressure-in-patients-undergoing-treatment
#13
Marvin Heyboer Rd, Susan M Wojcik, Garrett Smith, William Santiago
INTRODUCTION: Hyperbaric oxygen (HBO₂) therapy is generally safe and well tolerated. However, known side effects do exist. Elevation in the blood pressure of patients undergoing HBO₂ therapy is a less defined potential side effect. We sought to better quantify effects of HBO₂ on blood pressure (BP) in patients undergoing HBO₂. METHODS: A retrospective chart review was performed on quality assurance data captured on all patients undergoing HBO₂ between March 2012 and October 2015 at a large tertiary referral university hospital hyperbaric center...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777523/transient-osteoporosis-of-the-hip-treated-with-hyperbaric-oxygen-therapy-a-case-series
#14
Kazuyoshi Yagishita, Tetsuya Jinno, Daisuke Koga, Tsuyoshi Kato, Mitsuhiro Enomoto, Tsuyoshi Kato, Takeshi Muneta, Atsushi Okawa
INTRODUCTION: Transient osteoporosis of the hip (TOH) is a self-limiting disorder characterized by bone marrow edema at the femoral head and neck. Patients report pain as moderate or severe at onset; pain gradually subsides at about six months (range four to 12 months). Differential diagnosis of the early stages of osteonecrosis of the femoral head (ONFH) is sometimes difficult. Because hyperbaric oxygen (HBO₂) therapy is effective for reduction of edema in soft tissue injury and early stages of ONFH, we hypothesized that HBO₂ could be effective in TOH for accelerated recovery...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777519/effect-of-hyperbaric-oxygen-treatment-on-pilonidal-disease-surgery
#15
Feyzullah Ersoz, Soykan Arikan, Serkan Sari, Sefika Korpinar, Ozhan Ozcan, Bekir Poyraz, Sevim Purisa, Akin Savas Toklu
Surgical excision and lay-open is a well-known technique for the treatment of sacrococcygeal pilonidal disease, which impairs a patient's quality of life considerably since wound healing takes a substantial amount of time. It is known that with this method total healing period is longer, but recurrence rate of the disease is lower. The beneficial effects of hyperbaric oxygen (HBO₂) therapy on wound healing have been well established since it was first put into in clinical use. The purpose of this prospective randomized clinical trial was to investigate the effects of HBO₂ therapy on wound healing in the patients who had sacrococcygeal pilonidal disease and surgical treatment...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777517/changes-in-pulmonary-function-in-hyperbaric-chamber-inside-attendants-a-case-control-study
#16
Adem Ozdemir, Gunalp Uzun, Turker Turker, Turker Turker, Ergun Ucar, Senol Yildiz
BACKGROUND: Inside attendants (IAs) [are] exposed to high pressure during hyperbaric oxygen (HBO₂) therapy. The aim of this study was to evaluate the alterations of pulmonary functions in IAs over time. METHODS: IAs in our hyperbaric center constituted the IA group (n=11). A sex- and age-matched control group (n=15) was constituted from hospital staff who had not dived or been exposed to hyperbaric environments before. We measured the respiratory function of all subjects at two time points: 1) at the start of the study; and 2) 12 months after the first measurement...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777516/hyperbaric-oxygenation-affects-the-mechanisms-of-acetylcholine-induced-relaxation-in-diabetic-rats
#17
Sanela Unfirer, Martina Mihalj, Sanja Novak, Aleksandar Kibel, Ava Cavka, Zrinka Mijalevic, Mario Gros, Ivica Brizic, Danijela Budimir, Anita Cosic, Mladen Boban, Ines Drenjancevic
The effects of hyperbaric oxygenation (HBO₂) on acetylcholine-induced vasorelaxation (AChIR) were evaluated in male Sprague-Dawley (SD) rats randomized into four groups: healthy controls (Ctrl), diabetic rats (DM), and control and diabetic rats that underwent hyperbaric oxygenation (Ctrl+HBO₂ and DM+HBO₂). AChIR was measured in aortic rings, with L-NAME, indomethacin, or MS-PPOH and a combination of inhibitors. mRNA expression of eNOS, iNOS, COX-1 and COX-2 was assessed by qPCR, and protein expression of CYP4A(1-3) by Western blot...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777515/early-treatment-response-predicts-outcome-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss-treated-with-hyperbaric-oxygen-therapy
#18
Iclal Karatop-Cesur, Gunalp Uzun, Kubra Ozgok-Kangal, Mesut Mutluoglu, Senol Yildiz
Hyperbaric oxygen (HBO₂) therapy is used in the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL). Some patients, however, do not benefit from HBO₂ therapy despite several weeks of treatment. We hypothesized that early treatment response could predict treatment failure. We conducted a retrospective chart review and identified patients diagnosed with ISSNHL and recorded the pure tone average (PTA) levels prior to, after the first week and at completion of HBO₂ therapy. Early treatment response (ETR) was assessed after the first week of HBO₂ therapy, and an increase ⟨10 decibels (dB) in mean PTA level was defined as a negative ETR...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777514/our-experience-in-the-treatment-of-idiopathic-sensorineural-hearing-loss-isnhl-effect-of-combination-therapy-with-hbo%C3%A2-and-vasodilator-infusion-therapy
#19
Barbora Kratochvílovà, Oliver Profant, Jaromír Astl, Richard Holý
Idiopathic sensorineural hearing loss (ISNHL) is a hearing impairment that occurs suddenly with onset over a period of 24 to 72 hours, affecting at least three adjacent frequencies with hearing loss of 30 decibels or more, caused by damage to the inner ear or auditory nerve without clear reasons. The treatment of ISNHL is still a hot topic. In a retrospective study, we examined 88 patients with ISNHL (2008-2013). The objective of the study was to compare the effects of two different types of therapy: vasodilator infusion treatment combined with hyperbaric oxygen (HBO₂) therapy vs...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777513/rna-sequencing-analysis-reveals-new-findings-of-hyperbaric-oxygen-treatment-on-rats-with-acute-carbon-monoxide-poisoning
#20
Wenlan Wang, Li Xue, Ya Li, Rong Li, Xiaoping Xie, Junxiang Bao, Chunxu Hai, Jinsheng Li
OBJECTIVE: To elucidate the altered gene network in the brains of carbon monoxide (CO) poisoned rats after treatment with hyperbaric oxygen (HBO₂). METHODS: RNA sequencing (RNA-seq) analysis was performed to examine differentially expressed genes (DEGs) in brain tissue samples from nine male rats: a normal control group; a CO poisoning group; and an HBO₂ treatment group (three rats/group). Reverse transcription polymerase chain reaction (RT-PCR) and real-time quantitative PCR were used for validation of the DEGs in another 18 male rats (six rats/group)...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
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