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https://www.readbyqxmd.com/read/29451877/influence-of-hyperbaric-oxygen-on-biomechanics-and-structural-bone-matrix-in-type-1-diabetes-mellitus-rats
#1
Pedro Henrique Justino Oliveira Limirio, Huberth Alexandre da Rocha Junior, Richarlisson Borges de Morais, Karen Renata Nakamura Hiraki, Ana Paula Coelho Balbi, Priscilla Barbosa Ferreira Soares, Paula Dechichi
BACKGROUND: The aim of this study was to evaluate the biomechanics and structural bone matrix in diabetic rats subjected to hyperbaric oxygen therapy (HBO). METHODS: Twenty-four male rats were divided into the following groups: Control; Control + HBO; Diabetic, and Diabetic + HBO. Diabetes was induced with streptozotocin (STZ) in the diabetic Groups. After 30 days, HBO was performed every 48h in HBO groups and all animals were euthanized 60 days after diabetic induction...
2018: PloS One
https://www.readbyqxmd.com/read/29422841/detecting-pilot-s-engagement-using-fnirs-connectivity-features-in-an-automated-vs-manual-landing-scenario
#2
Kevin J Verdière, Raphaëlle N Roy, Frédéric Dehais
Monitoring pilot's mental states is a relevant approach to mitigate human error and enhance human machine interaction. A promising brain imaging technique to perform such a continuous measure of human mental state under ecological settings is Functional Near-InfraRed Spectroscopy (fNIRS). However, to our knowledge no study has yet assessed the potential of fNIRS connectivity metrics as long as passive Brain Computer Interfaces (BCI) are concerned. Therefore, we designed an experimental scenario in a realistic simulator in which 12 pilots had to perform landings under two contrasted levels of engagement (manual vs...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29392157/prefrontal-hemodynamic-changes-measured-using-near-infrared-spectroscopy-during-the-valsalva-maneuver-in-patients-with-orthostatic-intolerance
#3
Yoo Hwan Kim, Zephaniah Phillips V, Seung-Ho Paik, Nam-Joon Jeon, Beop-Min Kim, Byung-Jo Kim
The Valsalva maneuver (VM) with beat-to-beat blood pressure and heart rate monitoring are used to evaluate orthostatic intolerance (OI). However, they lack the ability to detect cerebral hemodynamic changes, which may be a cause of OI symptoms. Therefore, we utilized near-infrared spectroscopy during VM. Patients with OI symptoms and normal healthy subjects were recruited. Patients were subgrouped according to VM results: patients with normal VM (NVM) and abnormal VM (AbVM). Oxyhemoglobin (HbO), deoxyhemoglobin, and total hemoglobin changes were measured at four different source-detector distances (SD) (15, 30, 36, and 45 mm), and latency, amplitude, duration, and integrated total signal were calculated...
January 2018: Neurophotonics
https://www.readbyqxmd.com/read/29390550/successful-treatment-of-sudden-sensorineural-hearing-loss-by-means-of-pharmacotherapy-combined-with-early-hyperbaric-oxygen-therapy-case-report
#4
Dorota Olex-Zarychta
RATIONALE: According to the World Health Organization reports, adult-onset hearing loss is the 15th leading cause of burden of disease, and is projected to move up to 7th by the year 2030, especially in high-income countries. Sudden sensorineural hearing loss is considered by otologists as a true otologic emergency. The current standard treatment for sudden hearing loss is a tapered course of oral high-dose corticosteroids. The described clinical case points to the validity of undertaking early hyperbaric oxygenation (HBO) therapy together with corticosteroids for full recovery of adult onset idiopathic sudden sensorineural hearing loss...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29390534/toe-keloid-after-nail-extraction-treated-with-surgical-excision-a-case-report
#5
Hao Liu, Kexin Song, Mingzi Zhang, Xinhang Dong, Shu Liu, Youbin Wang
RATIONALE: In this study, a case of toe keloid after nail extraction is presented, in which the keloids on both toes were resected by surgical excision. Keloids (from the Greek word meaning "crab's claw") are fibrous growths that extend beyond the original area of injury to involve the adjacent normal skin. In general, keloid tendencies appear to be regionally isolated to keloid-prone areas, such as the chest, ears, and deltoid regions, whereas the hands and feet are usually spared, which is why this case is meaningful...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29383459/alterations-in-mitochondrial-respiration-and-reactive-oxygen-species-in-patients-poisoned-with-carbon-monoxide-treated-with-hyperbaric-oxygen
#6
David H Jang, Utsha G Khatri, Brenna P Shortal, Matthew Kelly, Kevin Hardy, David S Lambert, David M Eckmann
BACKGROUND: Carbon monoxide (CO) poisoning is the leading cause of poisoning mortality and morbidity in the USA. Carboxyhemoglobin (COHb) levels are not predictive of severity or prognosis. At this time, the measurement of mitochondrial respiration may serve as a biomarker in CO poisoning. The primary objective of this study was to assess changes in mitochondrial function consisting of respiration and generation of reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) obtained from patients with CO poisoning...
January 30, 2018: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/29383031/treatment-of-ulcerative-compared-to-non-ulcerative-interstitial-cystitis-with-hyperbaric-oxygen-a-pilot-study
#7
David L Wenzler, Farris Gulli, Maureen Cooney, Michael B Chancellor, Jason Gilleran, Kenneth M Peters
Background: The etiology of interstitial cystitis (IC) is often idiopathic but can be due to Hunner's ulcers. Hyperbaric oxygen (HBO) is used to treat ulcerative disease of the superficial skin. We hypothesized that HBO can treat ulcerative IC (UIC) but would be less efficacious for non-ulcerative IC (NIC). Methods: Patients with NIC and UIC enrolled in this study. Following informed consent, demographic information was collected. A visual analog pain scale and validated questionnaires were collected; each patient underwent cystoscopy prior to treatment...
December 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29378458/hyperbaric-oxygen-therapy-effects-on-bone-regeneration-in-type-1-diabetes-mellitus-in-rats
#8
Pâmella Coelho Dias, Pedro Henrique Justino Oliveira Limirio, Camila Rodrigues Borges Linhares, Mariana Lobo Bergamini, Flaviana Soares Rocha, Richarlisson Borges de Morais, Ana Paula Coelho Balbi, Karen Renata Nakamura Hiraki, Paula Dechichi
PURPOSE: The aim of this study was evaluate the effect of HBO on diabetic rats. MATERIALS AND METHODS: Twenty rats were distributed into four groups (n = 5): Control (C); Control + HBO (CH); Diabetes (D) and Diabetes + HBO (DH). Diabetes was induced by streptozotocin, and bone defects were created in both femurs in all animals. HBO therapy began immediately after surgery and was performed daily in the CH and DH groups. After seven days, the animals were euthanized...
January 29, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29377928/effect-of-hyperbaric-oxygen-therapy-hbo-on-implant-associated-osteitis-in-a-femur-fracture-model-in-mice
#9
Carina Büren, Tim Lögters, Lisa Oezel, Golnessa Rommelfanger, Armin Olaf Scholz, Joachim Windolf, Ceylan Daniela Windolf
Hyperbaric oxygen therapy (HBO) is applied very successfully in treatment of various diseases such as chronic wounds. It has been already suggested as adjunctive treatment option for osteitis by immune- and fracture modulating effects. This study evaluates the importance of HBO in an early implant-associated localized osteitis caused by Staphylococcus aureus (SA) compared to the standard therapy. In a standardized murine model the left femur of 120 BALB/c mice were osteotomized and fixed by a titanium locking plate...
2018: PloS One
https://www.readbyqxmd.com/read/29363648/increased-efficacy-of-antivenom-combined-with-hyperbaric-oxygen-on-deinagkistrodon-acutus-envenomation-in-adult-rats
#10
Mo Li, Zhi-Hui Xie, An-Yong Yu, Dong-Po He
BACKGROUND: Snakebites are a neglected threat to global human health with a high morbidity rate. The present study explored the efficacy of antivenom with hyperbaric oxygen (HBO) intervention on snakebites, which could provide the experimental basis for clinical adjuvant therapy. METHODS: Male Sprague-Dawley rats (n = 96) were randomized into four groups: the poison model was established by injecting Deinagkistrodon acutus (D. acutus) venom (0.8 LD50) via the caudal vein; the antivenom group was injected immediately with specific antivenom via the caudal vein after successful establishment of the envenomation model; and the antivenom + HBO group was exposed to HBO environment for 1 h once at predetermined periods of 0 h, 4 h, 12 h, and 23 h after antivenin administration...
February 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29358697/hyperbaric-oxygen-reduces-inflammation-oxygenates-injured-muscle-and-regenerates-skeletal-muscle-via-macrophage-and-satellite-cell-activation
#11
Takuya Oyaizu, Mitsuhiro Enomoto, Naoki Yamamoto, Kunikazu Tsuji, Masaki Horie, Takeshi Muneta, Ichiro Sekiya, Atsushi Okawa, Kazuyoshi Yagishita
Hyperbaric oxygen treatment (HBO) promotes rapid recovery from soft tissue injuries. However, the healing mechanism is unclear. Here we assessed the effects of HBO on contused calf muscles in a rat skeletal muscle injury model. An experimental HBO chamber was developed and rats were treated with 100% oxygen, 2.5 atmospheres absolute for 2 h/day after injury. HBO reduced early lower limb volume and muscle wet weight in contused muscles, and promoted muscle isometric strength 7 days after injury. HBO suppressed the elevation of circulating macrophages in the acute phase and then accelerated macrophage invasion into the contused muscle...
January 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29340072/hyperbaric-oxygen-protects-against-myocardial-reperfusion-injury-via-the-inhibition-of-inflammation-and-the-modulation-of-autophagy
#12
Chunxia Chen, Wan Chen, Yaoxuan Li, Yanling Dong, Xiaoming Teng, Zhihuan Nong, Xiaorong Pan, Liwen Lv, Ying Gao, Guangwei Wu
Our previous study demonstrated that hyperbaric oxygen (HBO) preconditioning protected against myocardial ischemia reperfusion injury (MIRI) and improved myocardial infarction. However, HBO's effect on MIRI-induced inflammation and autophagy remains unclear. In this study, we investigate the potential impact and underlying mechanism of HBO preconditioning on an MIRI-induced inflammatory response and autophagy using a ligation of the left anterior descending (LAD) coronary artery rat model. Our results showed that HBO restored myocardial enzyme levels and decreased the apoptosis of cardiomyocytes, which were induced by MIRI...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29325344/-experimental-observation-of-hyperbaric-oxygen-combined-with-radioactive-seed-implantation-in-the-treatment-of-nude-mice-bearing-esophageal-squamous-cell-carcinoma
#13
K Yue, L X Wan, C H Zhang, Z Jin, Y Shang, H Y Ma
Objective: To investigate the effect and mechanism of hyperbaric oxygen combined with radioactive seed implantation in the treatment of esophageal squamous cell carcinoma. Methods: Subcutaneous tumor model of esophageal squamous cell carcinoma using TE-8 cells was established. Tumor bearing Balb/c(nu/nu) mice (60 mice) were divided into four groups, Cont group that treated with normal oxygen level, HBO group that treated with hyperbaric oxygen, RSI group that treated with radioactive seed implantation, and HBO+ RSI group that treated with hyperbaric oxygen combined with radioactive seed implantation...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29281193/quantitative-romberg-s-test-in-acute-carbon-monoxide-poisoning-treated-by-hyperbaric-oxygen
#14
Daniel Bidstrup, Erik Christian Jansen, Ole Hyldegaard
OBJECTIVE: The aim of this study was to evaluate whether monitoring of acute carbon monoxide-poisoned (COP) patients by means of quantitative Romberg's test (QR-test) during a hyperbaric oxygen (HBO₂) therapy regimen could be a useful supplement in the evaluation of neurological status. METHODS: We conducted a retrospective study (2000-2014) in which we evaluated data containing quantitative sway measurements of acute COP patients (n = 58) treated in an HBO₂ regimen...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29281192/dried-salted-plum-consumption-ameliorates-hyperbaric-oxygen-therapy-induced-otalgia-severity-at-the-first-chamber-session-a-prospective-randomized-controlled-study
#15
Fan-Chun Meng, Chih-Hao Shen, Di Wu, Chi-Ming Chu, Cheng-Ping Shih, Hung-Che Lin, Chung-Kan Peng, Shun Cheng Chang, Kun-Lun Huang
PURPOSE: One of the most common complications of hyperbaric oxygen (HBO₂) therapy is middle ear barotrauma (MEB), occasionally causing otalgia. The objective of this study was to evaluate the effect of dried salted plum consumption on MEB and otalgia associated with HBO₂ therapy. MATERIALS AND METHODS: Patients undergoing the first chamber session of HBO₂ therapy were included in the present prospective randomized controlled trial. The Valsalva maneuver was administered to all patients before HBO₂...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29281191/hyperbaric-oxygen-suppresses-growth-of-klebsiella-pneumoniae-and-enhances-effect-of-tigecycline-in-vitro
#16
Lina Zhang, Qing Sun, Di Wu, Ying Yang, Tao Yu, Guangkai Gao
OBJECTIVES: (1) To examine whether hyperbaric oxygen (HBO₂) will inhibit growth of multidrug-resistant Klebsiella pneumoniae (MDR-K. pneumoniae) and extensively drug-resistant Klebsiella pneumoniae (XDR-K. pneumoniae); (2) To determine whether the effect of tigecycline on XDR-K. pneumoniae will be enhanced by HBO₂. METHODS: The effects of 1.5 hours of treatment with normoxia (21% O₂, 1 atmosphere absolute/ATA) or HBO₂ (100% O₂, 2 ATA) on bacterial counts of eight isolates of MDR-K...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29281190/hyperbaric-oxygen-therapy-as-an-adjuvant-to-source-control-in-necrotizing-soft-tissue-infections
#17
António Pedro Pinto Ferreira, Sérgio Santos Vide, Tiago David Fonseca Fernandes, Pedro Miguel Barata de Silva Coelho, Óscar Ferraz Camacho
INTRODUCTION: Necrotizing soft tissue infections (NSTI) are rare but potentially lethal disorders, and adequate management is time- and resource-demanding. This study aims to assess whether variations in the treatment modalities - surgery, hyperbaric oxygen (HBO₂) therapy and negative pressure wound therapy - had an impact on the length to definitive source control in NSTI patients who underwent HBO₂. METHODS: This is a retrospective study of all NSTI patients treated with hyperbaric oxygen therapy between March 2007 and May 2015 at Unidade Local de Saúde de Matosinhos (ULSM) Hyperbaric Unit...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29281189/influence-of-hyperoxia-on-diastolic-myocardial-and-arterial-endothelial-function
#18
T Wunderlich, N Frey, W Kähler, M Lutz, P Radermacher, S Klapa, I Koch, F Tillmans, J Witte, A Koch
OBJECTIVE: Hyperoxia is known to influence cardiovascular and endothelial function, but it is unknown if there are differences between younger and older persons. The aim of this study was to monitor changes in myocardial diastolic function and flow-mediated dilatation (FMD) in younger and elderly volunteers, before and after exposure to relevant hyperbaric hyperoxia. METHODS: 51 male patients were separated into two groups for this study. Volunteers in Group 1 (n=28, mean age 26 ±6, "juniors") and Group 2 (n=23, mean age 53 ±9, "seniors") received standard HBO₂ protocol (240kPa oxygen)...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29281187/review-on-hyperbaric-oxygen-treatment-in-femoral-head-necrosis
#19
Enrico Camporesi, Giuliano Vezzani, Vincenzo Zanon, Daniele Manelli, Garrett Enten, Silvia Quartesan, Gerardo Bosco
BACKGROUND: Femoral head necrosis (FHN) is a common invalidating disease with an unclear etiology and pathophysiology that affects middle-aged people. FHN may lead to joint collapse and require invasive treatments. Because of its clinical and socioeconomic significance, an early diagnosis, staging and appropriate treatment are required. Unfortunately, to date a unique algorithm for the treatment of FHN has not been defined. OBJECTIVE: In this report we summarize the Tenth European Consensus Conference on hyperbaric medicine (April 2016, France), during which experts from Europe revised the list of accepted indications for hyperbaric oxygen (HBO₂) treatment, including FHN...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29246132/neuroprotective-effects-of-hyperbaric-oxygen-hbo-therapy-on-neuronal-death-induced-by-sciatic-nerve-transection-in-rat
#20
Zahra Shams, Ali Reza Khalatbary, Hassan Ahmadvand, Zohreh Zare, Kosar Kian
BACKGROUND: Recent studies shows that hyperbaric oxygen (HBO) therapy exerts some protective effects against neural injuries. The purpose of this study was to determine the neuroprotective effects of HBO following sciatic nerve transection (SNT). METHODS: Rats were randomly divided into five groups (n = 14 per group): Sham-operated (SH) group, SH + HBO group, SNT group, and SNT + pre- and SNT + post-HBO groups (100% oxygen at 2.0 atm absolute, 60 min/day for five consecutive days beginning on 1 day before and immediately after nerve transaction, respectively)...
December 16, 2017: BMC Neurology
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