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https://www.readbyqxmd.com/read/29030623/monitoring-cerebral-hemodynamic-change-during-transcranial-ultrasound-stimulation-using-optical-intrinsic-signal-imaging
#1
Evgenii Kim, Eloise Anguluan, Jae Gwan Kim
Transcranial ultrasound stimulation (tUS) is a promising non-invasive approach to modulate brain circuits. The application is gaining popularity, however the full effect of ultrasound stimulation is still unclear and further investigation is needed. This study aims to apply optical intrinsic signal imaging (OISI) for the first time, to simultaneously monitor the wide-field cerebral hemodynamic change during tUS on awake animal with high spatial and temporal resolution. Three stimulation paradigms were delivered using a single-element focused transducer operating at 425 kHz in pulsed mode having the same intensity (ISPPA = 1...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29021747/hyperbaric-oxygen-environment-can-enhance-brain-activity-and-multitasking-performance
#2
Dor Vadas, Leonid Kalichman, Amir Hadanny, Shai Efrati
Background: The Brain uses 20% of the total oxygen supply consumed by the entire body. Even though, <10% of the brain is active at any given time, it utilizes almost all the oxygen delivered. In order to perform complex tasks or more than one task (multitasking), the oxygen supply is shifted from one brain region to another, via blood perfusion modulation. The aim of the present study was to evaluate whether a hyperbaric oxygen (HBO) environment, with increased oxygen supply to the brain, will enhance the performance of complex and/or multiple activities...
2017: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/28983908/interventions-for-managing-medication-related-osteonecrosis-of-the-jaw
#3
REVIEW
Natalie H Beth-Tasdogan, Benjamin Mayer, Heba Hussein, Oliver Zolk
BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and involves the progressive destruction of bone in the mandible or maxilla. Depending on the drug, its dosage, and the duration of exposure, the occurrence of this adverse drug reaction may be rare (e.g. following the oral administration of bisphosphonate or denosumab treatments for osteoporosis, or antiangiogenic agent-targeted cancer treatment) or common (e...
October 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28983491/mean-and-variability-in-functional-brain-activations-differentially-predict-executive-function-in-older-adults-an-investigation-employing-functional-near-infrared-spectroscopy
#4
Drew W R Halliday, Bryce P Mulligan, Douglas D Garrett, Stefan Schmidt, Sandra R Hundza, Mauricio A Garcia-Barrera, Robert S Stawski, Stuart W S MacDonald
OBJECTIVE: although the preponderance of research on functional brain activity investigates mean group differences, mounting evidence suggests that variability in neural activity is beneficial for optimal central nervous system (CNS) function. Independent of mean signal estimates, recent findings have shown that neural variability diminishes with age and is positively associated with cognitive performance, underscoring its adaptive nature. The present investigation sought to employ functional near infrared spectroscopy (fNIRS) to derive two operationalizations of cerebral oxygenation, representing mean and variability [using standard deviation (SD)] in neural activity, and to specifically contrast these mean- and SD-oxyhemoglobin (HbO) estimates as predictors of cognitive function...
January 2018: Neurophotonics
https://www.readbyqxmd.com/read/28953090/hyperbaric-oxygen-promotes-neural-stem-cell-proliferation-by-activating-vascular-endothelial-growth-factor-extracellular-signal-regulated-kinase-signaling-after-traumatic-brain-injury
#5
Yongkai Yang, Hao Wei, Xiaohui Zhou, Fan Zhang, Chunhua Wang
Hyperbaric oxygen (HBO) therapy and neural stem cell (NSC) transplantation can improve traumatic brain injury (TBI) clinically. This study aimed to investigate the mechanism of HBO promoting NSC proliferation and neurological recovery after TBI. Twenty-four Sprague-Dawley rats were divided randomly into three groups: a sham group, a TBI group (constructed using Feeney's free-fall method), and an HBO-treated TBI group. Neurological function was evaluated by Neurological Severity Scores on days 1, 3, and 7, and we found that TBI-induced poor neurological function was improved by HBO...
September 25, 2017: Neuroreport
https://www.readbyqxmd.com/read/28947973/hyperbaric-oxygen-protects-type-ii-collagen-in-interleukin-1%C3%AE-induced-mandibular-condylar-chondrocyte-via-inhibiting-the-jnk-c-jun-signaling-pathway
#6
Qi Sun, Gaoyi Wu, Hang Chen, Lei Chen, Hongyu Chen, Guoxiong Zhu, Huaqiang Zhao
The aim of this study was to explore the mechanisms of Hyperbaric oxygen (HBO) protective on interleukin-1β (IL-1β) induced rat's mandibular condylar chondrocytes. Chondrocytes were exposure to Hyperbaric oxygen after induced inflammatory by IL-1β. After that, the expression of p-JNK and c-Jun was increased significantly, while the Sox-9 was decreased significantly, Immunofluorescence results showed that the expression of p-JNK and p-c-Jun were decreased while the expression of Sox-9 and COL2 were increased in chondrocytes treated with IL-1β and selective JNK inhibitor...
September 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28937254/assessing-muscular-oxygenation-during-incremental-exercise-using-near-infrared-spectroscopy-comparison-of-three-different-methods
#7
N F Agbangla, M Audiffren, C T Albinet
Using continuous-wave near-infrared spectroscopy (NIRS), this study compared three different methods, namely the slope method (SM), the amplitude method (AM), and the area under the curve (AUC) method to determine the variations of intramuscular oxygenation level as a function of workload. Ten right-handed subjects (22+/-4 years) performed one isometric contraction at each of three different workloads (30%, 50% and 90% of maximal voluntary strength) during a period of twenty seconds. Changes in oxyhemoglobin (delta[HbO(2)]) and deoxyhemoglobin (delta[HHb]) concentrations in the superficial flexor of fingers were recorded using continuous-wave NIRS...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28937253/sirt1-mediates-improvement-in-cognitive-defects-induced-by-focal-cerebral-ischemia-following-hyperbaric-oxygen-preconditioning-in-rats
#8
P Ding, D Ren, S He, M He, G Zhang, Y Chen, H Sang, Z Peng, W Yan
Hyperbaric oxygen preconditioning (HBO-PC) has been proposed as a safe and practical approach for neuroprotection in ischemic stroke. However, it is not known whether HPO-PC can improve cognitive deficits induced by cerebral ischemia, and the mechanistic basis for any beneficial effects remains unclear. We addressed this in the present study using rats subjected to middle cerebral artery occlusion (MCAO) as an ischemic stroke model following HBO-PC. Cognitive function and expression of phosphorylated neurofilament heavy polypeptide (pNF-H) and doublecortin (DCX) in the hippocampus were evaluated 14 days after reperfusion and after short interfering RNA-mediated knockdown of sirtuin1 (Sirt1)...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28935857/sensorimotor-computation-underlying-phototaxis-in-zebrafish
#9
Sébastien Wolf, Alexis M Dubreuil, Tommaso Bertoni, Urs Lucas Böhm, Volker Bormuth, Raphaël Candelier, Sophia Karpenko, David G C Hildebrand, Isaac H Bianco, Rémi Monasson, Georges Debrégeas
Animals continuously gather sensory cues to move towards favourable environments. Efficient goal-directed navigation requires sensory perception and motor commands to be intertwined in a feedback loop, yet the neural substrate underlying this sensorimotor task in the vertebrate brain remains elusive. Here, we combine virtual-reality behavioural assays, volumetric calcium imaging, optogenetic stimulation and circuit modelling to reveal the neural mechanisms through which a zebrafish performs phototaxis, i.e...
September 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28927648/hyperbaric-oxygenation-alleviates-chronic-constriction-injury-cci-induced-neuropathic-pain-and-inhibits-gabaergic-neuron-apoptosis-in-the-spinal-cord
#10
Huiqun Fu, Fenghua Li, Sebastian Thomas, Zhongjin Yang
BACKGROUND AND AIMS: Dysfunction of GABAergic inhibitory controls contributes to the development of neuropathic pain. We examined our hypotheses that (1) chronic constriction injury (CCI)-induced neuropathic pain is associated with increased spinal GABAergic neuron apoptosis, and (2) hyperbaric oxygen therapy (HBO) alleviates CCI-induced neuropathic pain by inhibiting GABAergic neuron apoptosis. METHODS: Male rats were randomized into 3 groups: CCI, CCI+HBO and the control group (SHAM)...
September 15, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28914230/prefrontal-cortical-responses-in-children-with-prenatal-alcohol-related-neurodevelopmental-impairment-a-functional-near-infrared-spectroscopy-study
#11
Julie A Kable, Claire D Coles
OBJECTIVE: Disruption in the neural activation of the prefrontal cortex (PFC) in modulating arousal was explored in children with heavy prenatal alcohol exposure (PAE), who have known neurobehavioral impairment. METHODS: During a task that elicits frustration, functional near-infrared spectroscopy (fNIRS) was used to measure PFC activation, specifically levels of oxygenated (HBO) and deoxygenated (HBR) hemoglobin, in children with PAE (n=18) relative to typically developing Controls (n=12) and a Clinical Contrast group with other neurodevelopmental or behavioral problems (n=14)...
September 2, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28883864/the-efficacy-of-hyperbaric-oxygen-in-hemorrhagic-stroke-experimental-and-clinical-implications
#12
Robert P Ostrowski, Katarzyna Stępień, Emanuela Pucko, Ewa Matyja
Hemorrhagic stroke, accounting for 10-30% of stroke cases, carries high rates of morbidity and mortality. This review presents the current knowledge on the efficacy of hyperbaric oxygen (HBO)-based modalities in the preclinical research on hemorrhagic stroke. Both preconditioning and post-treatment with HBO are considered as prospective therapeutic options. High efficacy of HBO therapy (HBOT) for brain hemorrhage has been noted. We found that moderate hyperbaric pressures appear optimal for therapeutic effect, while the therapeutic window of opportunity is short...
August 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28860917/hyperbaric-oxygen-in-the-management-of-wound-tissue-necrosis-after-external-dacrocystorhinostomy
#13
Alicia Galindo-Ferreiro, Ahmed Ghetami, Diego Strianese, Sahar Elkhamary, Deepak P Edward, Antonio Palma, Silvana A Schellini
Hyperbaric oxygen is an adjunctive treatment for promoting wound healing and reducing infection. We present an unusual case of wound tissue necrosis occurring after external dacryocystorhinostomy (ExtDCR) that was subsequently treated with hyperbaric oxygen (HBO) and advancement flaps with good outcome. HBO improves vascularization of ischemic tissues after ExtDCR for greater success after reconstructive surgery.
July 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28857997/cervical-necrotizing-fasciitis-of-odontogenic-origin-and-hyperbaric-oxygen-therapy
#14
Caner Hakki Inan, Haydar Murat Yener, Mehmet Yilmaz, Emine Deniz Gözen, Zülküf Burak Erdur, Bengüsu Oroğlu, Eren Olcay, Nermin Memmedova
Necrotizing fasciitis (NF) is an infection of the soft tissues pathology with high mortality that spreads through the fascial planes and rarely seen in head and neck region. The cause of infection is often odontogenic problems. Broad-spectrum antibiotics, surgical debridement, and hyperbaric oxygen therapy (HBO) are important for the treatment of disease. We report a case of cervical NF in a 33-year-old woman who was treated with rapid surgical debridement and simultaneous HBO.
October 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28840158/utilizing-functional-near-infrared-spectroscopy-for-prediction-of-cognitive-workload-in-noisy-work-environments
#15
Ryan Gabbard, Mary Fendley, Irfaan A Dar, Rik Warren, Nasser H Kashou
Occupational noise frequently occurs in the work environment in military intelligence, surveillance, and reconnaissance operations. This impacts cognitive performance by acting as a stressor, potentially interfering with the analysts' decision-making process. We investigated the effects of different noise stimuli on analysts' performance and workload in anomaly detection by simulating a noisy work environment. We utilized functional near-infrared spectroscopy (fNIRS) to quantify oxy-hemoglobin (HbO) and deoxy-hemoglobin concentration changes in the prefrontal cortex (PFC), as well as behavioral measures, which include eye tracking, reaction time, and accuracy rate...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/28838774/the-role-of-hyperbaric-oxygen-therapy-in-the-prevention-and-management-of-radiation-induced-complications-of-the-head-and-neck-%C3%A2-a-systematic-review-of-literature
#16
P Ravi, D Vaishnavi, A Gnanam, V B Krishnakumar Raja
Radiation therapy for the treatment of head and neck cancer can injure normal tissues and have devastating side effects. Hyperbaric oxygen (HBO) is known to reduce the severity of radiation-induced injury by promoting wound healing. While most of the research in literature has focused on its efficacy in osteonecrosis, HBO has other proven benefits as well. The aim of this review was to identify the various benefits of hyperbaric oxygen therapy in patients who have undergone radiation for head and neck cancer...
August 22, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28838565/a-case-of-methemoglobinemia-successfully-treated-with-hyperbaric-oxygenation-monotherapy
#17
Youngmo Cho, Sung Wook Park, Sang-Kyoon Han, Hyung Bin Kim, Seok Ran Yeom
BACKGROUND: Methylene blue is the first-line therapy for methemoglobinemia, but it can be intermittently unavailable due to production issues. For this clinical scenario, alternative treatment options need to be explored. Hyperbaric oxygenation (HBO) is conventionally applied as an adjunctive therapy during the systemic administration of methylene blue. Currently, little is known regarding the effects of HBO monotherapy in methemoglobinemia. We report a case of methemoglobinemia that was successfully treated with HBO monotherapy...
August 21, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28810963/treating-decompression-sickness-military-flight-simulation-site-community-hospital-partnership
#18
Whitney C Rhodes, George Hertner, Robert Price, Lani Finck, Claudia Temmer, Tracy Cushing, Kathleen Flarity
BACKGROUND: High-altitude flight simulation familiarizes military trainees with the symptoms of hypoxia to prepare them for emergency situations. Decompression sickness (DCS) can occur as a result of these simulations. In cases when ground-level supplemental oxygen does not resolve symptoms, hyperbaric oxygen (HBO) therapy is indicated. Many military hyperbaric chambers have been closed because of cost reductions, necessitating partnerships with community hospitals to ensure access to treatment...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28790369/arginyl-dipeptides-increase-the-frequency-of-nacl-elicited-responses-via-epithelial-sodium-channel-alpha-and-delta-subunits-in-cultured-human-fungiform-taste-papillae-cells
#19
Jiao-Jiao Xu, Nadia Elkaddi, Alvaro Garcia-Blanco, Andrew I Spielman, Alexander A Bachmanov, Hau Yin Chung, Mehmet Hakan Ozdener
Salty taste is one of the five basic tastes and is often elicited by NaCl. Because excess sodium intake is associated with many health problems, it could be useful to have salt taste enhancers that are not sodium based. In this study, the regulation of NaCl-induced responses was investigated in cultured human fungiform taste papillae (HBO) cells with five arginyl dipeptides: Ala-Arg (AR), Arg-Ala (RA), Arg-Pro (RP), Arg-Glu (RE), and Glu-Arg (ER); and two non-arginyl dipeptides: Asp-Asp (DD) and Glu-Asp (ED)...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28783893/delayed-treatment-of-frostbite-with-hyperbaric-oxygen-a-report-of-two-cases
#20
Corine A Lansdorp, Gert R Roukema, Onno Boonstra, Jan Dokter
Frostbite is an injury caused by the freezing of tissue, causing varied levels of tissue damage and necrosis. Case reports have shown a positive effect of hyperbaric oxygen (HBO₂) in such injuries, in acute cases as well as delayed (up to 21 days) presentation with complications. In this case report we present the course of hyperbaric treatment of two patients (a brother and sister, age 58 and 62) who sustained frostbite injuries to both feet 28 days earlier while hiking in the Himalayas. They were initially treated in Nepal following local protocol; afterward their primary care in the Netherlands was managed by the Burn Centre at Maasstad Hospital in Rotterdam...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
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