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https://www.readbyqxmd.com/read/28723746/effects-of-hyperbaric-oxygen-therapy-on-depression-and-anxiety-in-the-patients-with-incomplete-spinal-cord-injury-a-strobe-compliant-article
#1
Juan-Juan Feng, You-Hui Li
Little research has been done on the effects of hyperbaric oxygen (HBO) on depression and anxiety after spinal cord injury (SCI). The aim of this study was to investigate the effects of HBO on psychological problems and never function, especially on depression and anxiety in the patients with incomplete SCI (ISCI).Sixty patients with ISCI combined with depression and anxiety were randomly divided into HBO group (20 cases), psychotherapy group (20 cases), and conventional rehabilitation control group (20 cases)...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28690173/immediate-and-delayed-hyperbaric-oxygen-therapy-as-a-neuroprotective-treatment-for-traumatic-brain-injury-in-mice
#2
Renana Baratz-Goldstein, Shlomi Toussia-Cohen, Aviya Elpaz, Vardit Rubovitch, Chaim G Pick
BACKGROUND: Traumatic brain injury is the most common cause of death or chronic disability among people under-35-years-old. There is no effective pharmacological treatment currently existing for TBI. Hyperbaric oxygen therapy (HBOT) is defined as the inhalation of pure oxygen in a hyperbaric chamber that is pressurized higher than 1atm. HBOT offers physiological and mechanical effects by inducing a state of increased pressure and hyperoxia. HBOT has been proposed as an effective treatment for moderate traumatic brain injury (mTBI), yet the exact therapeutic window and mechanism that underlies this effect is not completely understood...
July 8, 2017: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/28673282/hyperbaric-oxygen-treatment-of-spinal-cord-injury-in-rat-model
#3
Yongming Sun, Dong Liu, Qingpeng Wang, Peng Su, Qifeng Tang
BACKGROUND: The purpose of this study was to investigate the therapeutic effects and mechanisms of hyperbaric oxygen (HBO) treatment on rats following spinal cord injury (SCI). METHODS: A total of 45 Sprague-Dawley (SD) rats were randomly divided into three groups. Sham-SCI group was surgically exposed but not subjected to the SCI procedure. SCI-control group was administered SCI and treated with regular air. SCI-HBO group was administered SCI and HBO treatment...
July 3, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28668280/classification-of-somatosensory-cortex-activities-using-fnirs
#4
Keum-Shik Hong, M Raheel Bhutta, Xiaolong Liu, Yong-Il Shin
The ability of the somatosensory cortex in differentiating various tactile sensations is very important for a person to perceive the surrounding environment. In this study, we utilize a lab-made multi-channel functional near-infrared spectroscopy (fNIRS) to discriminate the hemodynamic responses (HRs) of four different tactile stimulations (handshake, ball grasp, poking, and cold temperature) applied to the right hand of eight healthy male subjects. The activated brain areas per stimulation are identified with the t-values between the measured data and the desired hemodynamic response function...
June 28, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28645025/decreased-functional-connectivity-and-disrupted-neural-network-in-the-prefrontal-cortex-of-affective-disorders-a-resting-state-fnirs-study
#5
Huilin Zhu, Jie Xu, Jiangxue Li, Hongjun Peng, Tingting Cai, Xinge Li, Shijing Wu, Wei Cao, Sailing He
BACKGROUND: Affective disorders (AD) have been conceptualized as neural network-level diseases. In this study, we utilized functional near infrared spectroscopy (fNIRS) to investigate the spontaneous hemodynamic activities in the prefrontal cortex (PFC) of the AD patients with or without medications. METHODS: 42 optical channels were applied to cover the superior frontal gyrus (SFG), middle frontal gyrus (MFG), and inferior frontal gyrus (IFG), which constitute one of the most important affective networks of the brain...
October 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28641323/ischaemia-reperfusion-injury-and-hyperbaric-oxygen-pathways-a-review-of-cellular-mechanisms
#6
REVIEW
Ashish Francis, Richard Baynosa
Ischaemia-induced tissue injury has wide-ranging clinical implications including myocardial infarction, stroke, compartment syndrome, ischaemic renal failure and replantation and revascularization. However, the restoration of blood flow produces a 'second hit' phenomenon, the effect of which is greater than the initial ischaemic event and characterizes ischaemia-reperfusion (IR) injury. Some examples of potential settings of IR injury include: following thrombolytic therapy for stroke, invasive cardiovascular procedures, solid organ transplantation, and major trauma resuscitation...
June 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28638297/pediatric-nasal-tip-amputation-successfully-treated-with-nonmicrovascular-replantation-and-hyperbaric-oxygen-therapy
#7
Jason D Pou, H Devon Graham
BACKGROUND: Nasal tip amputation is a rare but difficult problem to manage. Nonmicrovascular nasal tip replantation is a valid and relatively simple repair option for moderate nasal defects, but tissue ischemia and graft failure occur frequently. CASE REPORT: We present the case of a pediatric nasal tip amputation from a dog bite treated with replantation within 5 hours. The 2.5-cm avulsed tip contained skin, cartilage, and mucosa and was replanted as a 3-layer composite graft...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28584411/effectiveness-of-hyperbaric-oxygen-therapy-in-irradiated-maxillofacial-dental-implant-patients-a-systematic-review-with-meta-analysis
#8
REVIEW
Darshana Nilesh Shah, Chirag Jasubhai Chauhan, Jenish Sureshbhai Solanki
The significantly higher implant failure rates in maxillofacial patients, undergoing radiotherapy, might be caused by the long-term effects of reduced vascularization compromising the implantation site. An extensive preclinical animal literature and a multitude of clinical reports suggest the use of hyperbaric oxygen (HBO) therapy as it can improve the tissue vascularity. Hence, it may increase the implant survival rate by enhancing osseointegration process in such patients. The objective of this systematic review was to investigate the effectiveness of HBO therapy on dental implant survival rate in irradiated maxillofacial patients who require prosthodontic rehabilitation...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28581561/2-phenylbenzoxazole-derivatives-a-family-of-robust-emitters-of-solid-state-fluorescence
#9
Chantal Carayon, Suzanne Fery-Forgues
The derivatives of 2-phenylbenzoxazole (PBO) are popular fluorescent organic dyes for use in solution or after dispersion in an appropriate matrix. Their spectroscopic behavior in the solid state is, unjustly, not so well known. Many of them are strongly emissive as pure solid dyes, due to a favorable crystal packing mode. The PBO fragment lends itself well to relatively simple modifications of its chemical structure, aimed at enlarging the conjugated π-electron system. Many molecules thus designed show aggregation-induced emission (AIE)...
July 1, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28555597/hyperbaric-oxygen-therapy-as-salvage-therapy-for-sudden-sensorineural-hearing-loss
#10
Jakov Ajduk, Mihael Ries, Robert Trotic, Ivana Marinac, Kovacic Vlatka, Vladimir Bedekovic
OBJECTIVE: To measure the effect of hyperbaric oxygen (HBO) therapy as salvage therapy after the failure of steroid therapy for sudden sensorineural hearing loss (SSNHL). MATERIALS AND METHODS: Ninety-three patients with SSNHL were unsuccessfully treated with systemic steroid therapy. Following steroid therapy, 43 patients received additional HBO therapy while 50 did not. Hearing levels at 0.25, 0.5, 1, 2, 4, and 8 kHz before and after therapy were measured. RESULTS: A significant difference in hearing thresholds after HBO therapy was found at all frequencies in patients with a hearing loss of >61 dB...
April 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28547651/photoplethysmography-for-blood-volumes-and-oxygenation-changes-during-intermittent-vascular-occlusions
#11
T Y Abay, P A Kyriacou
Photoplethysmography (PPG) is an optical technique that measures blood volume variations. The main application of dual-wavelength PPG is pulse oximetry, in which the arterial oxygen saturation (SpO[Formula: see text]) is calculated noninvasively. However, the PPG waveform contains other significant physiological information that can be used in conjunction to SpO[Formula: see text] for the assessment of oxygenation and blood volumes changes. This paper investigates the use of near infrared spectroscopy (NIRS) processing techniques for extracting relative concentration changes of oxygenated ([Formula: see text]HbO[Formula: see text]), reduced ([Formula: see text]HHb) and total haemoglobin ([Formula: see text]tHb) from dual-wavelength PPG signals during intermittent pressure-increasing vascular occlusions...
May 25, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28542481/effect-of-hyperbaric-oxygen-on-bdnf-release-and-neuroprotection-investigations-with-human-mesenchymal-stem-cells-and-genetically-modified-nih3t3-fibroblasts-as-putative-cell-therapeutics
#12
Jennifer Schulze, Odett Kaiser, Gerrit Paasche, Hans Lamm, Andreas Pich, Andrea Hoffmann, Thomas Lenarz, Athanasia Warnecke
Hyperbaric oxygen therapy (HBOT) is a noninvasive widely applied treatment that increases the oxygen pressure in tissues. In cochlear implant (CI) research, intracochlear application of neurotrophic factors (NTFs) is able to improve survival of spiral ganglion neurons (SGN) after deafness. Cell-based delivery of NTFs such as brain-derived neurotrophic factor (BDNF) may be realized by cell-coating of the surface of the CI electrode. Human mesenchymal stem cells (MSC) secrete a variety of different neurotrophic factors and may be used for the development of a biohybrid electrode in order to release endogenously-derived neuroprotective factors for the protection of residual SGN and for a guided outgrowth of dendrites in the direction of the CI electrode...
2017: PloS One
https://www.readbyqxmd.com/read/28538801/effects-of-hyperbaric-oxygen-and-nerve-growth-factor-on-the-long-term-neural-behavior-of-neonatal-rats-with-hypoxic-ischemic-brain-damage
#13
Lixia Wei, Qing Ren, Yongjun Zhang, Jiwen Wang
Purpose: To evaluate the effects of HBO (Hyperbaric oxygen) and NGF (Nerve growth factor) on the long-term neural behavior of neonatal rats with HIBD (Neonatal hypoxic ischemic brain damage). Methods: The HIBD model was produced by ligating the right common carotid artery of 7 days old SD (Sprague-Dawley) rats followed by 8% O2 + 92% N2 for 2h. Totally 40 rats were randomly divided into 5 groups including sham-operated group, HIBD control group, HBO treated group, NGF treated group and NGF + HBO treated group...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28502690/the-clinical-effect-of-postoperative-hyperbaric-oxygen-therapy-on-idiopathic-normal-pressure-hydrocephalus-a-retrospective-and-comparative-analysis-of-61-patients-with-ventriculoperitoneal-shunt
#14
Lin Yang, Xingdong Wang, Yuping Li, Lang Chen, Zhengcun Yan, Lei She, Jun Dong
OBJECTIVE: The aim of the study was to examine the clinical effect of postoperative hyperbaric oxygen (HBO) therapy on symptoms and signs in the ventriculoperitoneal (VP) shunt insertion treatment of idiopathic normal pressure hydrocephalus (iNPH). METHODS: We conducted a retrospective analysis of 61 patients treated at our institution for iNPH since 2007. Patients were stratified into 2 groups according to undergoing pure VP shunt with gravitational valves (group 1) or combined with postoperative HBO therapy (group 2)...
August 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28495827/hyperbaric-oxygen-reduces-infarction-volume-and-hemorrhagic-transformation-through-atp-nad-sirt1-pathway-in-hyperglycemic-middle-cerebral-artery-occlusion-rats
#15
Qin Hu, Anatol Manaenko, Hetao Bian, Zongduo Guo, Jun-Long Huang, Zhen-Ni Guo, Peng Yang, Jiping Tang, John H Zhang
BACKGROUND AND PURPOSE: Energy depletion is a critical factor leading to cell death and brain dysfunction after ischemic stroke. In this study, we investigated whether energy depletion is involved in hyperglycemia-induced hemorrhagic transformation after ischemic stroke and determined the pathway underlying the beneficial effects of hyperbaric oxygen (HBO). METHODS: After 2-hour middle cerebral artery occlusion, hyperglycemia was induced by injecting 50% dextrose (6 mL/kg) intraperitoneally at the onset of reperfusion...
June 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28473763/the-optimal-speed-for-cortical-activation-of-passive-wrist-movements-performed-by-a-rehabilitation-robot-a-functional-nirs-study
#16
Sung Jin Bae, Sung Ho Jang, Jeong Pyo Seo, Pyung Hun Chang
Objectives: To advance development of rehabilitation robots, the conditions to induce appropriate brain activation during rehabilitation performed by robots should be optimized, based on the concept of brain plasticity. In this study, we examined differences in cortical activation according to the speed of passive wrist movements performed by a rehabilitation robot. Methods: Twenty three normal subjects participated in this study. Passive movements of the right wrist were performed by the wrist rehabilitation robot at three different speeds: 0...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28470432/the-no-cgmp-pkg-signal-transduction-pathway-is-involved-in-the-analgesic-effect-of-early-hyperbaric-oxygen-treatment-of-neuropathic-pain
#17
Yuanyuan Ding, Peng Yao, Tao Hong, Zhenkai Han, Baisong Zhao, Weimin Chen
BACKGROUND: Hyperbaric oxygen (HBO) has the potential to relieve neuropathic pain. The purpose of this study was to determine whether the NO-cGMP-PKG signaling pathway is involved in the analgesic effects of early hyperbaric oxygen treatment of neuropathic pain in rats. METHODS: Rats were randomly grouped for establishment of chronic constriction injury (CCI) models. Intrathecal catheters were inserted and 2.5ATA HBO therapy was administered from day 1 post-surgery for 60 minutes daily, continuously for 5 days; menstruum NS, DMSO, NO synthase(NOS) nonspecific inhibitor (L-NAME), soluble guanylyl cyclase(sGC) inhibitor (ODQ) and protein kinase G(PKG) inhibitor (KT5823) were administered intrathecally 30 minutes prior to HBO therapy...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28426381/hyperbaric-oxygen-for-experimental-intracerebral-haemorrhage-systematic-review-and-stratified-meta-analysis
#18
Han-Jin Cui, Hao-Yu He, A-Li Yang, Hua-Jun Zhou, Tao Tang, Jie-Kun Luo
OBJECTIVE: Hyperbaric oxygen (HBO) is widely used in treating various neurological diseases. However, HBO for treatment of intracerebral haemorrhage (ICH) remains controversial, in either animal or clinical studies. Therefore, we conducted this systematic review and meta-analysis on studies describing the efficacy of HBO in animal models of ICH. METHODS: Studies were identified by searching mainstream databases through November 2015. The efficacy of HBO in animal models of ICH was assessed by changes in the brain water content (BWC), neurobehavioural outcome (NO) or both...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28413648/effects-of-hyperbaric-oxygen-treatment-on-gastric-cancer-cell-line-sgc7901
#19
Yinliang Qi, Jianfeng Ruan, Mei Wang, Yuanchang Dai, Qing Zhou, Shuyu Gui, Sumei Zhang, Yuan Wang
Hyperbaric oxygen (HBO) has been previously identified as an effective adjunct treatment option for the management of brain injury, diabetic ulcers and chronic wounds. However, the roles of HBO as an adjunctive therapy for tumors remain controversial. The present research project was performed to explore the effects of HBO treatment on proliferation, autophagy and endoplasmic reticulum stress response of the gastric cancer cell line, SGC7901. The present study demonstrated that, after subjecting SGC7901 cells to HBO treatment, the increase in cell proliferation was significant, compared with that of the control group...
April 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28410116/hyperbaric-oxygenation-for-resuscitation-and-therapy-of-elderly-patients-with-cerebral-and-cardio-respiratory-dysfunction
#20
REVIEW
Gennady G Rogatsky, Ilia Stambler
Hyperbaric oxygenation therapy (HBOT) has been gaining an increasing recognition as a versatile therapeutic approach. This article reviews the application of hyperbaric oxygenation as a method for resuscitation and therapy of elderly patients with cerebral and cardio-respiratory dysfunction, in acute as compared to chronic impairments. The vital role of proper dosage of HBO therapy to ensure both the efficacy and safety of the treatment is emphasized. We argue that in the acute stages of brain and cardiorespiratory impairment, the adequate hyperbaric oxygen dose is the most important condition for obtaining maximum therapeutic effect, due to the powerful anti-hypoxic capabilities of this method...
June 1, 2017: Frontiers in Bioscience (Scholar Edition)
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