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Medical marijuana epidemiology

Aaron L Sarvet, Melanie M Wall, Katherine M Keyes, Mark Olfson, Magdalena Cerdá, Deborah S Hasin
BACKGROUND: Self-medication with drugs or alcohol is commonly reported among adults with mood or anxiety disorders, and increases the risk of developing substance use disorders. Medical marijuana laws (MML) may be associated with greater acceptance of the therapeutic value of marijuana, leading individuals to self-medicate. METHODS: The study utilized data from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (2004-2005). Participants were sampled from households in the general population and included adults with a mood or anxiety disorder in the past 12 months (n = 7418), and the subset of those who used marijuana and no other drug (n = 314)...
March 2, 2018: Drug and Alcohol Dependence
Mark Olfson, Melanie Wall, Shang-Min Liu, Michael Schoenbaum, Carlos Blanco
INTRODUCTION: Despite recent declining mortality of the U.S. population from most leading causes, uncertainty exists over trends in health-related quality of life. METHODS: The 2001-2002 and 2012-2013 National Epidemiologic Surveys on Alcohol and Related Conditions U.S. representative household surveys were analyzed for trends in health-related quality of life (n=79,402). Health-related quality of life was measured with the Short Form-6 Dimension scale derived from the Short Form-12...
January 12, 2018: American Journal of Preventive Medicine
Elizabeth L Pestka, Julia Craner, Michele Evans, Virginia Nash, Njoki Kimondo, Deborah Pestka, Larissa Loukianova, Jeannie Sperry
The objectives of this study were to examine association between a family history of substance abuse and admission morphine equivalent dose, depression and pain catastrophizing screening scores, as well as reported personal history of substance use. The retrospective research was completed in an interdisciplinary three-week pain rehabilitation center. The subject cohort included admissions from January through December 2014 with 351 datasets for family history of substance abuse and oral morphine equivalency and 341 for depression, pain catastrophizing and use of substances...
November 15, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
V Varlet
Users of e-cigarettes are unwitting volunteers participating in a worldwide epidemiological study. Because of the obvious benefits of e-cigarettes compared with traditional cigarette smoking, these electronic devices have been introduced all around the world to support tobacco smoking cessation. Same potential harm reduction could be considered by cannabis vaping for marijuana smokers. However, the toxicities of liquids and aerosols remain under investigation because although the use of e-cigarettes is likely to be less harmful than traditional cigarette smoking, trace levels of contaminants have been identified...
December 16, 2016: Toxics
Mofiyinfolu Sokoya, Justin Eagles, Tyler Okland, Dylan Coughlin, Hannah Dauber, Christopher Greenlee, Andrew A Winkler
INTRODUCTION: The effect of marijuana on human health has been studied extensively. Marijuana intoxication has been shown to affect performance, attention span, and reaction time. The public health relationship between trauma and cannabis use has also been studied, with mixed conclusions. In this report, the effect of marijuana legalization on many aspects of facial trauma at two hospitals in Denver, Colorado is examined. METHODS: A retrospective review of the electronic medical records was undertaken...
October 7, 2017: American Journal of Emergency Medicine
William C Kerr, Camillia Lui, Yu Ye
BACKGROUND AND AIMS: Epidemiological trends show marijuana use in the United States to have increased in recent years. Previous research has identified cohort effects as contributing to the rising prevalence, in particular birth cohorts born after 1945. However, given recent policy efforts to regulate marijuana use at the state level, period effects could also play a contributory role. This study aimed to examine whether cohort or period effects play a larger role in explaining trends in marijuana use...
September 12, 2017: Addiction
Deborah S Hasin
This review provides an overview of the changing US epidemiology of cannabis use and associated problems. Adults and adolescents increasingly view cannabis as harmless, and some can use cannabis without harm. However, potential problems include harms from prenatal exposure and unintentional childhood exposure; decline in educational or occupational functioning after early adolescent use, and in adulthood, impaired driving and vehicle crashes; cannabis use disorders (CUD), cannabis withdrawal, and psychiatric comorbidity...
January 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
Namkee G Choi, Diana M DiNitto, Carl Nathan Marti
BACKGROUND AND OBJECTIVE: Given that 29 U.S. states now have laws allowing medical marijuana use, this study examined mental and physical health correlates of medical versus nonmedical marijuana use among three age groups of adults (18-29, 30-49, and 50+). METHODS: Data came from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions (N = 36,309 respondents aged 18+). Logistic regression models were used to examine age group differences in associations of substance use and mental disorders and health conditions with medical versus nonmedical marijuana use...
October 2017: American Journal on Addictions
Nicholas Pintori, Barbara Loi, Maddalena Mereu
Spice drugs are herbal mixtures sprayed with synthetic cannabinoids designed to mimic the psychoactive ingredient in marijuana [Δ-tetrahydrocannabinol (Δ-THC)] and synthesized by introducing modifications to the chemical structure of parental compounds aiming to circumvent legal regulations. Synthetic cannabinoid use/abuse can be devastating as toxicological effects and adverse reactions cannot be entirely predicted and may vary with the dose, route of administration, individual vulnerability and concomitant intake with other drugs...
September 2017: Behavioural Pharmacology
Deborah S Hasin, Aaron L Sarvet, Magdalena Cerdá, Katherine M Keyes, Malka Stohl, Sandro Galea, Melanie M Wall
Importance: Over the last 25 years, illicit cannabis use and cannabis use disorders have increased among US adults, and 28 states have passed medical marijuana laws (MML). Little is known about MML and adult illicit cannabis use or cannabis use disorders considered over time. Objective: To present national data on state MML and degree of change in the prevalence of cannabis use and disorders. Design, Participants, and Setting: Differences in the degree of change between those living in MML states and other states were examined using 3 cross-sectional US adult surveys: the National Longitudinal Alcohol Epidemiologic Survey (NLAES; 1991-1992), the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; 2001-2002), and the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III; 2012-2013)...
June 1, 2017: JAMA Psychiatry
Bryce Pardo
BACKGROUND AND AIMS: In the United States, overdose deaths attributed to opioid pain relievers (OPR) have quadrupled since 1999, prompting many states to adopt Prescription Drug Monitoring Programs (PMP). This study aimed to: (1) estimate the relationship of PMP strength with OPR overdose deaths across states and over time; (2) measure what threshold in PMP strength is associated with the greatest reduction in OPR overdose; and (3) assess the relationship of medical marijuana dispensaries with OPR overdose deaths...
December 23, 2016: Addiction
James C Anthony, Catalina Lopez-Quintero, Omayma Alshaarawy
BACKGROUND: Globally, the most widely used set of compounds among the internationally regulated drugs is cannabis. OBJECTIVE: To review evidence from epidemiological research on cannabis, organized in relation to this field's five main rubrics: quantity, location, causes, mechanisms, and prevention/ control. METHOD: The review covers a selection of evidence from standardized population surveys, official statistics, and governmental reports, as well as published articles and books identified via MEDLINE, Web of Science, and Google Scholar as of July 2016...
January 4, 2017: Current Pharmaceutical Design
Chittaranjan Andrade
Psychosis is one of the most serious among the adverse effects associated with cannabis use. The association between cannabis use and psychosis has been variously explored in a series of recent meta-analyses. The results of these meta-analyses show that persons who develop psychosis experience onset of psychosis about 2-3 years earlier if they are cannabis users; this effect is not observed with alcohol or other substance use. Higher levels of cannabis use are associated with greater risk of psychosis. Current cannabis abuse or dependence (but not past use or lower levels of current use) increases the risk of transition into psychosis in persons at ultrahigh risk of psychosis...
June 2016: Journal of Clinical Psychiatry
Mark M Silvestri, Christopher J Correia
Recent epidemiological data indicate an increasing trend in the nonmedical use of prescription drugs among college students. The nonmedical use of prescription drugs involves using a prescription medication without a prescription, or using the medication in a manner inconsistent with a health care provider's instructions. Among college students, prescription stimulants have the highest ratio of nonmedical to medical use and the highest rate of illicit selling and trading on college campuses. The increased prevalence is accompanied by increased risk, as 18-25-year-olds have the highest rate of emergency department visits for nonmedical use of prescription stimulants (NMUPS)...
2016: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
Carlos Blanco, Deborah S Hasin, Melanie M Wall, Ludwing Flórez-Salamanca, Nicolas Hoertel, Shuai Wang, Bradley T Kerridge, Mark Olfson
IMPORTANCE: With rising rates of marijuana use in the general population and an increasing number of states legalizing recreational marijuana use and authorizing medical marijuana programs, there are renewed clinical and policy concerns regarding the mental health effects of cannabis use. OBJECTIVE: To examine prospective associations between cannabis use and risk of mental health and substance use disorders in the general adult population. DESIGN, SETTING, AND PARTICIPANTS: A nationally representative sample of US adults aged 18 years or older was interviewed 3 years apart in the National Epidemiologic Survey on Alcohol and Related Conditions (wave 1, 2001-2002; wave 2, 2004-2005)...
April 2016: JAMA Psychiatry
Timmen L Cermak
This article begins with a case vignette exemplifying the common clinical problem of heavy marijuana users. The epidemiology and basic science underlying cannabis dependence is outlined, followed by clinical strategies for basing a therapeutic alliance on known research findings and using motivational interviewing to deal with typical patterns of denial.
January 2016: Journal of Psychoactive Drugs
Ivan Senta, Ivona Krizman, Marijan Ahel, Senka Terzic
Besides the common illicit drugs, such as cocaine, heroin, and marijuana, there is a growing concern about the use of modern "designer drugs" that have emerged in large numbers over the past few years. In this work, a sensitive and selective method for simultaneous determination of 25 synthetic amphetamine-like psychoactive compounds, including amphetamine, sympathomimetic substituted amphetamines, synthetic cathinones and ketamine, in raw wastewater (RW), secondary effluent (SE) and river water was developed...
December 18, 2015: Journal of Chromatography. A
Daryl Shorter, John Hsieh, Thomas R Kosten
BACKGROUND AND OBJECTIVES: Post-traumatic Stress Disorder (PTSD) and substance use disorders (SUD) frequently co-occur, and their combination can increase poor health outcomes as well as mortality. METHODS: Using PUBMED and the list of references from key publications, this review article covered the epidemiology, neurobiology and pharmacotherapy of PTSD with comorbid alcohol, opiate, and cannabis use disorders. These SUD represent two with and one without FDA approved pharmacotherapies...
December 2015: American Journal on Addictions
Jessica A Kahn, Bret J Rudy, Jiahong Xu, Elizabeth A Secord, Bill G Kapogiannis, Sarah Thornton, Maura L Gillison
BACKGROUND: Little is known about the epidemiology or risk factors for oral human papillomavirus (HPV) in HIV-infected youth. The objectives of this study were to determine the prevalence and correlates of oral HPV infection and to explore the association between HPV vaccination and oral infection in HIV-infected youth. METHODS: Youth 12 to 24 years of age with behaviorally acquired HIV were recruited for this cross-sectional study. Procedures involved medical chart review, survey, and collection of an oral rinse sample...
May 2015: Sexually Transmitted Diseases
Michael D Stein, Debra S Herman, Genie L Bailey, John Straus, Bradley J Anderson, Lisa A Uebelacker, Risa B Weisberg
BACKGROUND: Pain and depression are each prevalent among opioid dependent patients receiving maintenance buprenorphine, but their interaction has not been studied in primary care patients. OBJECTIVE: We set out to examine the relationship between chronic pain, depression, and ongoing substance use, among persons maintained on buprenorphine in primary care settings. DESIGN: Between September 2012 and December 2013, we interviewed buprenorphine patients at three practice sites...
July 2015: Journal of General Internal Medicine
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