Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Aybuke Acar, Anthony Zampino, Neel Fotedar
Epileptic nystagmus (EN) is a subtle seizure semiology, most commonly seen in seizures originating in the posterior cortical regions. EN is broadly categorized into type I and type II. Type I EN consists of contralateral repetitive saccadic eye movements alternating with post-saccadic slow drifts with an overall contralateral deviation. Type II EN is characterized by ipsilateral slow drift alternating with contralateral corrective saccades. In this article, we report a method to perform oculographic analysis of eye movements using EEG only...
January 26, 2024: Epilepsy Research
#22
REVIEW
Jakob Paungarttner, Martina Quartana, Lucrezia Patti, Barbora Sklenárová, Fatemeh Farham, Inés Hernando Jiménez, M Gokcen Soylu, Irina Maria Vlad, Semih Tasdelen, Teresa Mateu, Oreste Marsico, Federica Reina, Viktoria Tischler, Christian Lampl
BACKGROUND: Migraine and epilepsy are two paroxysmal chronic neurological disorders affecting a high number of individuals and being responsible for a high individual and socioeconomic burden. The link between these disorders has been of interest for decades and innovations concerning diagnosing and treatment enable new insights into their relationship. FINDINGS: Although appearing to be distinct at first glance, both diseases exhibit a noteworthy comorbidity, shared pathophysiological pathways, and significant overlaps in characteristics like clinical manifestation or prophylactic treatment...
January 26, 2024: Journal of Headache and Pain
#23
İlknur Sürücü Kara, Engin Köse, Büşranur Çavdarlı, Fatma Tuba Eminoğlu
OBJECTIVES: Neuronal ceroid lipofuscinosis type 11 (NCL11) is a rare disease that presents with progressive cognitive decline, epilepsy, visual impairment, retinal atrophy, cerebellar ataxia and cerebellar atrophy. We present herein a case of NCL11 in a patient diagnosed with neuromotor developmental delay, epilepsy, bronchiolitis obliterans and hypothyroidism. CASE PRESENTATION: A 4-year-old male patient was admitted to our clinic with global developmental delay and a medical history that included recurrent hospitalizations for pneumonia at the age of 17 days, and in months 4, 5 and 7...
January 23, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
#24
JOURNAL ARTICLE
Andrew Janson, Lucas Sainburg, Behnaz Akbarian, Graham W Johnson, Baxter P Rogers, Catie Chang, Dario J Englot, Victoria L Morgan
OBJECTIVE: To understand the potential behavioral and cognitive effects of mesial temporal resection for temporal lobe epilepsy (TLE) a method is required to characterize network-wide functional alterations caused by a discrete structural disconnection. The objective of this study was to investigate network-wide alterations in brain dynamics of patients with TLE before and after surgical resection of the seizure focus using average regional controllability (ARC), a measure of the ability of a node to influence network dynamics...
January 19, 2024: Epilepsia
#25
JOURNAL ARTICLE
Sheng-Ping Li, Lung-Chang Lin, Rei-Cheng Yang, Chen-Sen Ouyang, Yi-Hung Chiu, Mu-Han Wu, Yi-Fang Tu, Tung-Ming Chang, Rong-Ching Wu
Childhood absence epilepsy (CAE) is a common type of idiopathic generalized epilepsy, manifesting as daily multiple absence seizures. Although seizures in most patients can be adequately controlled with first-line antiseizure medication (ASM), approximately 25 % of patients respond poorly to first-line ASM. In addition, an accurate method for predicting first-line medication responsiveness is lacking. We used the quantitative electroencephalogram (QEEG) features of patients with CAE along with machine learning to predict the therapeutic effects of valproic acid in this population...
January 16, 2024: Epilepsy & Behavior: E&B
#26
JOURNAL ARTICLE
Jodi L Smith, Jeremy Wertz, Arnold Lippa, Xingjie Ping, Xiaoming Jin, James M Cook, Jeffrey M Witkin, Rok Cerne
A clinical case of a 19-year-old male patient with pharmacoresistant seizures occurring following parieto-occipital tumor-resection at age 6 is described. Seizure surgery work-up included prolonged video EEG monitoring and head CT without contrast. Seizure focus was localized to the left temporal lobe, and we felt that the patient was an excellent candidate for seizure surgery. The patient underwent a left frontotemporal craniotomy for removal of the seizure focus with intraoperative electrocorticography (ECoG) conducted pre and post resection...
January 15, 2024: Heliyon
#27
JOURNAL ARTICLE
Galymzhan Issabekov, Takahiro Matsumoto, Hideyuki Hoshi, Keisuke Fukasawa, Sayuri Ichikawa, Yoshihito Shigihara
PURPOSE: Epilepsy is a prevalent neurological disorder characterised by repetitive seizures. It is categorised into three types: generalised epilepsy (GE), focal epilepsy (FE), and combined generalised and focal epilepsy. Correctly subtyping the epilepsy is important to select appropriate treatments. The types are mainly determined (i.e., diagnosed) by their semiologies supported by clinical examinations, such as electroencephalography and magnetoencephalography (MEG). Although these examinations are traditionally based on visual inspections of interictal epileptic discharges (IEDs), which are not always visible, alternative analyses have been anticipated...
February 2024: Seizure: the Journal of the British Epilepsy Association
#28
JOURNAL ARTICLE
Nicholas Fearns, Matias Wagner, Ingo Borggräfe, Mathias Kunz, Jan Rémi, Christian Vollmar
Pathogenic variants in COL4A1, encoding the alpha chain of type IV collagen, have been associated with cerebrovascular pathology as well as malformations of cortical development, thereby causing structural epilepsy. This case illustrates successful resective epilepsy surgery in a 12-month-old girl with left occipital focal cortical dysplasia (FCD) associated with a heterozygous splice-donor variant in COL4A1. She presented with drug-resistant focal epilepsy with daily seizures from the age of 2 months, refractory to several combinations of antiseizure medications, as well as mild right-sided hemiparesis and developmental delay...
January 2, 2024: Neuropediatrics
#29
JOURNAL ARTICLE
Zeynep Gokce-Samar, Annalisa Vetro, Julitta De Bellescize, Tiziana Pisano, Laloe Monteiro, Noémie Penaud, Christian M Korff, Joel Fluss, Carla Marini, Elisabetta Cesaroni, Blanca Mercedes Alvarez, Damien Sanlaville, Nicolas Chatron, Alexis A Arzimanoglou, Audrey Labalme, Vishnu A Cuddapah, Sarah M Ruggiero, Francois Lecoquierre, Gael Nicolas, Guerrot Anne Marie, Axel Lebas, Herve O Testard, Katherine L Helbig, Anna Ruiz, Adeline Ngoh, Manju A Kurian, Kimberley Reid, Robert Spaull, Pascal Joset, Georgia Ramantani, Katharina Steindl, Martin Krenn, Lucia Gerstl, Silvia Vieker, Dana Craiu, Manuela Pendziwiat, Chad Haldeman-Englert, Ilya Kanivets, Irina Romanova, Deepa S Rajan, Jill A Rosenfeld, Margaret Au, Katheryn Grand, John Graham, Arnaud Isapof, Nathalie Villeneuve, Thomas Smol, Roseline Caumes, Pia Zacher, Sonja Neuser, Sigrid Tinschert, Konrad Platzer, Tobias Bartolomaeus, Ines Mohnke, Maximilian Radtke, Rami Abou Jamra, Ingo Helbig, Floortje E Jansen, Klaas Koop, Gabrielle Rudolf, Sebastien Küry, Julien Courchet, Renzo Guerrini, Gaetan Lesca
BACKGROUND AND OBJECTIVES: Heterozygous variants in RAR-related orphan receptor B ( RORB ) have recently been associated with susceptibility to idiopathic generalized epilepsy. However, few reports have been published so far describing pathogenic variants of this gene in patients with epilepsy and intellectual disability (ID). In this study, we aimed to delineate the epilepsy phenotype associated with RORB pathogenic variants and to provide arguments in favor of the pathogenicity of variants...
January 23, 2024: Neurology
#30
JOURNAL ARTICLE
Jinxin Bu, Hangxing Yin, Nanxiao Ren, Haitao Zhu, Honghao Xu, Rui Zhang, Shugang Zhang
PURPOSE: To investigate brain network properties and connectivity abnormalities of the default mode network (DMN) in drug-resistant epilepsy (DRE). The study was based on probabilistic fiber tracking and functional connectivity (FC) analysis, to explore the structural and functional connectivity patterns change between frontal lobe epilepsy (FLE) and temporal lobe epilepsy (TLE). METHODS: A total of 33 DRE patients (18 TLE and 15 FLE) and 30 healthy controls (HCs) were recruited...
December 28, 2023: Epilepsy & Behavior: E&B
#31
JOURNAL ARTICLE
Rosa Ferrer Tarrés, Marina Garcia Huguet, Carla Vera Cáceres, Almudena Boix Lago, LLuís Ramió Torrentà, Gary Álvarez-Bravo
OBJECTIVES: Shapiro's syndrome (SS) is a rare condition characterized by spontaneous periodic hypothermia. The underlying pathophysiological mechanisms and etiology of this syndrome remain controversial, and fewer than 100 cases have been reported to date. The objective of this case report is to present a unique iatrogenic case of SS and contribute additional insights into the underlying etiology of this rare disorder. METHODS: We conducted an analysis of existing medical literature and described a clinical case of SS secondary to a neurosurgical procedure...
December 28, 2023: Neurological Sciences
#32
JOURNAL ARTICLE
Dorian M Kusyk, Nicholas Blaney, Timothy Quezada, Alexander C Whiting
BACKGROUND: Responsive neural stimulation (RNS) is a relatively novel procedure for drug-resistant epilepsy, which involves implantation of a device into the skull and brain. As more devices are implanted, there may be an increasing need to perform intracranial electrocorticography in implant patients with persistent seizures. Given the device location, imaging difficulties with implanted devices, and other technical hurdles, stereoelectroencephalography (SEEG) could be especially challenging...
December 11, 2023: J Neurosurg Case Lessons
#33
JOURNAL ARTICLE
Yulei Sun, Qi Shi, Min Ye, Ailiang Miao
OBJECTIVE: Although intracranial electrical stimulation has emerged as a treatment option for various diseases, its impact on the properties of brain networks remains challenging due to its invasive nature. The combination of intracranial electrical stimulation and whole-brain functional magnetic resonance imaging (fMRI) in patients with refractory epilepsy (RE) makes it possible to study the network properties associated with electrical stimulation. Thus, our study aimed to investigate the brain network characteristics of RE patients with concurrent electrical stimulation and obtain possible clinical biomarkers...
2023: Frontiers in Neuroscience
#34
JOURNAL ARTICLE
Chang Liu, Qingzhu Liu, Hao Yu, Yu Sun, Yao Wang, Guojing Yu, Shuang Wang, Xiaoyan Liu, Yuwu Jiang, Lixin Cai
BACKGROUND: The study aimed to summarize the indications and clinical features of pediatric drug-resistant epilepsy associated with early brain injury, surgical outcomes, and prognostic factors. METHODS: We retrospectively analyzed children diagnosed with drug-resistant epilepsy due to early brain injury, who had undergone surgery at the Pediatric Epilepsy Center of Peking University First Hospital from May 2014 to May 2021. Clinical data of vasculogenic and non-vasculogenic injuries from early brain damage were compared and analyzed...
December 8, 2023: Epilepsy & Behavior: E&B
#35
JOURNAL ARTICLE
Yao Ding, Zhidong Cen, Yang Zheng, Xia Qiu, Yumao Ye, Xinhui Chen, Lingli Hu, Bo Wang, Zhongjin Wang, Houmin Yin, Chunhong Shen, Wenjie Ming, Yi Ge, Fei Xie, Dehao Yang, Zhiyuan Ouyang, Haotian Wang, Sheng Wu, Meiping Ding, Shuang Wang, Wei Luo
OBJECTIVES: To investigate and characterize epileptic seizures and electrophysiological features of familial cortical myoclonic tremor with epilepsy (FCMTE) type 1 patients in a large Chinese cohort. METHODS: We systematically evaluated 125 FCMTEtype 1 patients carrying the pentanucleotide (TTTCA) repeat expansion in the SAMD12 gene in China. RESULTS: Among the 28 probands, epileptic seizures (96.4%, 27/28) were the most common reason for an initial clinic visit...
December 7, 2023: Annals of Clinical and Translational Neurology
#36
JOURNAL ARTICLE
Jiajie Mo, Wenyu Dong, Lin Sang, Zhong Zheng, Qiang Guo, Xiuming Zhou, Wenjing Zhou, Haixiang Wang, Xianghong Meng, Yi Yao, Fengpeng Wang, Wenhan Hu, Kai Zhang, Xiaoqiu Shao
BACKGROUND: Posterior cortex epilepsy (PCE) primarily comprises seizures originating from the occipital, parietal, and/or posterior edge of the temporal lobe. Electroclinical dissociation and subtle imaging representation render the diagnosis of PCE challenging. Improved methods for accurately identifying patients with PCE are necessary. OBJECTIVES: To develop a novel voxel-based image postprocessing method for better visual identification of the neuroimaging abnormalities associated with PCE...
2023: Therapeutic Advances in Neurological Disorders
#37
JOURNAL ARTICLE
Silke Ethofer, Monika Milian, Michael Erb, Sabine Rona, Jürgen Honegger, Thomas Ethofer
OBJECTIVE: We aimed to investigate differences in episodic memory networks between patients with temporal lobe epilepsy (TLE) due to hippocampal sclerosis and healthy controls, especially with regards to the parietal memory network (PMN), as well as their relation to neuropsychological memory performance after mesial temporal resection. METHODS: 28 healthy subjects as well as 21 patients with TLE (12 left, 9 right) were investigated using a spatial memory fMRI paradigm, which has been shown to activate the PMN...
November 28, 2023: Epilepsia Open
#38
JOURNAL ARTICLE
Georgia M Wong, Katherine Hofmann, Nathan A Shlobin, Tammy N Tsuchida, William D Gaillard, Chima O Oluigbo
Emerging neuromodulatory treatments, such as deep brain stimulation (DBS) and responsive neurostimulation (RNS), have shown promise in reducing drug-resistant seizures. While centromedian thalamic nucleus and anterior thalamic nucleus stimulation have been effective in certain types of seizures, limited research has explored pulvinar nucleus stimulation for epilepsy. To address this gap, we conducted a systematic review and individual patient data analysis. Of 78 resultant articles, 5 studies with transient stimulation and chronic stimulation of the pulvinar nucleus were included...
December 2023: Clinical Neurology and Neurosurgery
#39
JOURNAL ARTICLE
Karin Westin, Sándor Beniczky, Christoph Pfeiffer, Matti Hämäläinen, Daniel Lundqvist
OBJECTIVE: Epilepsy surgery requires localization of the seizure onset zone (SOZ). Today this can only be achieved by intracranial electroencephalography (iEEG). The iEEG electrode placement is guided by findings from non-invasive modalities that cannot themselves detect SOZ-generated initial seizure activity. On scalp magnetoencephalography (osMEG), with sensors placed on the scalp, demonstrates higher sensitivity than conventional MEG (convMEG) and could potentially detect early seizure activity...
December 2023: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
#40
JOURNAL ARTICLE
Ji Hye Shin, Min Ji Song, Ji Hyun Kim
Recent morphometric MRI studies suggested the possibility that valproate (VPA) use is associated with parieto-occipital cortical thinning in patients with heterogeneous epilepsy syndromes. In this study, we examined the effect of VPA on the brain volume using a large number of homogenous patients with idiopathic generalized epilepsy. Voxel-based morphometry was used to compare regional grey matter (GM) volume between 112 patients currently taking VPA (VPA+ group), 81 patients not currently taking VPA (VPA- group), and 120 healthy subjects (control group)...
November 9, 2023: Epilepsia
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
