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Occipital epilepsy

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https://www.readbyqxmd.com/read/27923187/sleep-eeg-patterns-in-infants-with-congenital-zika-virus-syndrome
#1
Maria Durce Costa Gomes Carvalho, Demócrito de Barros Miranda-Filho, Vanessa van der Linden, Paula Fabiana Sobral, Regina Coeli Ferreira Ramos, Maria Ângela Wanderley Rocha, Marli Tenório Cordeiro, Sarah Pinheiro de Alencar, Magda Lahorgue Nunes
OBJECTIVES: To describe sleep EEG patterns of neonates, and infants with microcephaly due to congenital Zika virus (ZikV) syndrome. METHODS: A descriptive case series of EEGs performed in a cohort of neonates with microcephaly monitored from October 2015 to February 2016 at a University Hospital in Northeast Brazil. Infants were investigated following an established protocol that includes EEG, neuroimaging studies, PCR and specific antibodies for ZikV detection...
November 14, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27899123/a-functional-magnetic-resonance-imaging-investigation-of-visual-hallucinations-in-the-human-striate-cortex
#2
Hina Abid, Fayyaz Ahmad, Soo Y Lee, Hyun W Park, Dongmi Im, Iftikhar Ahmad, Safee U Chaudhary
PURPOSE: Human beings frequently experience fear, phobia, migraine and hallucinations, however, the cerebral mechanisms underpinning these conditions remain poorly understood. Towards this goal, in this work, we aim to correlate the human ocular perceptions with visual hallucinations, and map them to their cerebral origins. METHODS: An fMRI study was performed to examine the visual cortical areas including the striate, parastriate and peristriate cortex in the occipital lobe of the human brain...
November 29, 2016: Behavioral and Brain Functions: BBF
https://www.readbyqxmd.com/read/27895559/reorganization-of-visual-callosal-connections-following-alterations-of-retinal-input-and-brain-damage
#3
REVIEW
Laura Restani, Matteo Caleo
Vision is a very important sensory modality in humans. Visual disorders are numerous and arising from diverse and complex causes. Deficits in visual function are highly disabling from a social point of view and in addition cause a considerable economic burden. For all these reasons there is an intense effort by the scientific community to gather knowledge on visual deficit mechanisms and to find possible new strategies for recovery and treatment. In this review, we focus on an important and sometimes neglected player of the visual function, the corpus callosum (CC)...
2016: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/27889818/somatosensory-reflex-seizures-in-a-child-with-epilepsy-related-to-novel-scn1a-mutation
#4
Pinar Arican, Nihal Olgac Dundar, Dilek Cavusoglu, Taha Resid Ozdemır, Pinar Gencpinar
INTRODUCTION: Mutations in SCN1A have been reported in patients with different types of epilepsy, including generalized epilepsy with febrile seizures plus, severe myoclonic epilepsy in infancy, malignant migrating partial seizures in infancy, and other infantile epileptic encephalopathies. CASE REPORT: We report a case of a 10-month-old girl presented with reflex epileptic seizures provoked by somatosensory stimuli with a novel de novo mutation of SCN1A gene. She was observed to have seizures with eye deviation, unresponsiveness provoked by somatosensory stimuli of the face...
November 26, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27888083/clinical-and-imaging-evaluation-of-the-transuncus-selective-amygdalo-hippocampectomy
#5
Enrico Ghizoni, Roger Matias, Stefan Lieber, Brunno Machado de Campos, Clarissa Lin Yasuda, João Paulo Sant Ana Santos de Souza, Pamela Castro Pereira, Augusto Amato, Andrei Fernandes Joaquim, Tátila Martins Lopes, Helder Tedeschi, Fernando Cendes
BACKGROUND: Various reports described the transuncus approach (TU) as a selective route to the amygdala and hippocampus, but this approach has not yet being submitted to a solid post operative imaging analysis. The objective of this study was to evaluate the anatomy, surgical technique, postoperative imaging analysis and outcome in a series of temporal lobe epilepsy (TLE) patients who underwent to selective amigdalo-hippocampectomy (SHA) via TU. METHODS: This is a prospective study of 25 consecutive patients who underwent to selective amigdalo-hippocampectomy through TU...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27878136/phenotypic-convergence-of-menkes-and-wilson-disease
#6
Boglarka Bansagi, David Lewis-Smith, Endre Pal, Jennifer Duff, Helen Griffin, Angela Pyle, Juliane S Müller, Gabor Rudas, Zsuzsanna Aranyi, Hanns Lochmüller, Patrick F Chinnery, Rita Horvath
Menkes disease is an X-linked multisystem disorder with epilepsy, kinky hair, and neurodegeneration caused by mutations in the copper transporter ATP7A. Other ATP7A mutations have been linked to juvenile occipital horn syndrome and adult-onset hereditary motor neuropathy.(1,2) About 5%-10% of the patients present with "atypical Menkes disease" characterized by longer survival, cerebellar ataxia, and developmental delay.(2) The intracellular copper transport is regulated by 2 P type ATPase copper transporters ATP7A and ATP7B...
December 2016: Neurology. Genetics
https://www.readbyqxmd.com/read/27859033/stereo-electroencephalography-guided-radiofrequency-thermocoagulation-seeg-guided-rf-tc-in-drug-resistant-focal-epilepsy-results-from-a-10-year-experience
#7
Pierre Bourdillon, Jean Isnard, Hélène Catenoix, Alexandra Montavont, Sylvain Rheims, Philippe Ryvlin, Karine Ostrowsky-Coste, François Mauguiere, Marc Guénot
OBJECTIVE: Stereo electroencephalography (SEEG)-guided radiofrequency thermocoagulation (SEEG-guided RF-TC) has been proposed since 2004 as a possible treatment of some focal drug-resistant epilepsy. The aim of this study is to provide extensive data about efficacy and safety of SEEG-guided RF-TC. METHODS: Over a 10-year period, 162 patients with drug-resistant focal epilepsy were eligible for SEEG-guided RF-TG during phase II invasive investigation by SEEG. All follow-up and safety data were collected prospectively...
November 16, 2016: Epilepsia
https://www.readbyqxmd.com/read/27830114/disruptions-in-cortico-subcortical-covariance-networks-associated-with-anxiety-in-new-onset-childhood-epilepsy
#8
Camille Garcia-Ramos, Jack J Lin, Leonardo Bonilha, Jana E Jones, Daren C Jackson, Vivek Prabhakaran, Bruce P Hermann
Anxiety disorders represent a prevalent psychiatric comorbidity in both adults and children with epilepsy for which the etiology remains controversial. Neurobiological contributions have been suggested, but only limited evidence suggests abnormal brain volumes particularly in children with epilepsy and anxiety. Since the brain develops in an organized fashion, covariance analyses between different brain regions can be investigated as a network and analyzed using graph theory methods. We examined 46 healthy children (HC) and youth with recent onset idiopathic epilepsies with (n = 24) and without (n = 62) anxiety disorders...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27816896/simultaneous-seeg-meg-eeg-recordings-overcome-the-seeg-limited-spatial-sampling
#9
Martine Gavaret, Anne-Sophie Dubarry, Romain Carron, Fabrice Bartolomei, Agnès Trébuchon, Christian-George Bénar
During presurgical evaluation of pharmacoresistant partial epilepsies, stereoelectroencephalography (SEEG) records interictal and ictal activities directly but is inherently limited in spatial sampling. In contrast, scalp-EEG and MEG are less sensitive but provide a global view on brain activity. Therefore, recording simultaneously these three modalities should provide a better understanding of the underlying brain sources by taking advantage of the different sensitivities of the three recording techniques...
December 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27792884/altered-basal-ganglia-cortical-functional-connections-in-frontal-lobe-epilepsy-a-resting-state-fmri-study
#10
Li Dong, Pu Wang, Rui Peng, Sisi Jiang, Benjamin Klugah-Brown, Cheng Luo, Dezhong Yao
OBJECTIVES: The purpose of this study was to investigate alterations of basal ganglia-cortical functional connections in patients with frontal lobe epilepsy (FLE). METHOD: Resting-state functional magnetic resonance imaging (fMRI) data were gathered from 19 FLE patients and 19 age- and gender-matched healthy controls. Functional connectivity (FC) analysis was used to assess the functional connections between basal ganglia and cerebral cortex. Regions of interest, including the left/right caudate, putamen, pallidum and thalamus, were selected as the seeds...
December 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27785033/vagus-nerve-stimulation-balanced-disrupted-default-mode-network-and-salience-network-in-a-postsurgical-epileptic-patient
#11
Kailiang Wang, Qi Chai, Hui Qiao, Jianguo Zhang, Tinghong Liu, Fangang Meng
INTRODUCTION: In recent years, treatment of intractable epilepsy has become more challenging, due to an increase in resistance to antiepileptic drugs, as well as diminished success following resection surgery. Here, we present the case of a 19-year old epileptic patient who received vagus nerve stimulation (VNS) following unsuccessful left parietal-occipital lesion-resection surgery, with results indicating an approximate 50% reduction in seizure frequency and a much longer seizure-free interictal phase...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27744245/glutamate-concentrations-vary-with-antiepileptic-drug-use-and-mental-slowing
#12
Tamar M van Veenendaal, Dominique M IJff, Albert P Aldenkamp, Richard H C Lazeron, Nicolaas A J Puts, Richard A E Edden, Paul A M Hofman, Anton J A de Louw, Walter H Backes, Jacobus F A Jansen
OBJECTIVE: Although antiepileptic drugs (AEDs) are effective in suppressing epileptic seizures, they also induce (cognitive) side effects, with mental slowing as a general effect. This study aimed to assess whether concentrations of MR detectable neurotransmitters, glutamate and GABA, are associated with mental slowing in patients with epilepsy taking AEDs. METHODS: Cross-sectional data were collected from patients with localization-related epilepsy using a variety of AEDs from three risk categories, i...
October 13, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27728902/changes-in-corticocortical-and-corticohippocampal-network-during-absence-seizures-in-wag-rij-rats-revealed-with-time-varying-granger-causality
#13
Marina V Sysoeva, Lyudmila V Vinogradova, Galina D Kuznetsova, Ilya V Sysoev, Clementina M van Rijn
PURPOSE: Spike-and-wave discharges (SWDs) recorded in the cortical EEGs of WAG/Rij rats are the hallmark for absence epilepsy in this model. Although this type of epilepsy was long regarded as a form of primary generalized epilepsy, it is now recognized that there is an initiation zone - the perioral region of the somatosensory cortex. However, networks involved in spreading the seizure are not yet fully known. Previously, the dynamics of coupling between different layers of the perioral cortical region and between these zones and different thalamic nuclei was studied in time windows around the SWDs, using nonlinear Granger causality...
October 8, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27665526/the-retrieval-of-perceptual-memory-details-depends-on-right-hippocampal-integrity-and-activation
#14
Marie St-Laurent, Morris Moscovitch, Mary Pat McAndrews
We assessed whether perceptual richness, a defining feature of episodic memory, depends on the engagement and integrity of the hippocampus during episodic memory retrieval. We tested participants' memory for complex laboratory events (LEs) that differed in perceptual content: short stories were either presented as perceptually rich film clips or as perceptually impoverished narratives. Participants underwent functional magnetic resonance imaging (fMRI) while retrieving these LEs (narratives and clips), as well as events from their personal life (autobiographical memories)...
August 27, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/27662337/occipito-frontal-sharp-waves-an-under-recognized-eeg-pattern-in-self-limited-idiopathic-childhood-focal-epilepsy
#15
Elaine Wyllie, Ahsan Nv Moosa
We report four children who highlight the potentially under-recognized EEG pattern of bilaterally synchronous occipito-frontal sharp waves, which may occur in children with Panayiotopoulos-type self-limited childhood epilepsy but may be easily confused with the patterns of symptomatic generalized epilepsy. Our patients were young, healthy children who had infrequent, predominantly nocturnal, fairly prolonged seizures characterized by altered consciousness, vomiting, and autonomic features, or in one case nocturnal secondary generalized tonic clonic convulsion...
September 16, 2016: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/27661438/alteration-of-the-alertness-related-network-in-patients-with-right-temporal-lobe-epilepsy-a-resting-state-fmri-study
#16
Jianping Li, Xuemei Chen, Wei Ye, Wenyu Jiang, Huihua Liu, Jinou Zheng
OBJECTIVES: This study aimed to investigate alterations in the alertness-related network in patients with right temporal lobe epilepsy (rTLE) and explore the functional mechanisms of impaired alertness. METHODS: We recruited twenty patients with rTLE and eighteen matched healthy controls. All participants took a neuropsychological attention network test (ANT) and underwent resting-state functional magnetic resonance imaging (rs-fMRI) scanning. We extracted the alertness-related network using multiple independent component analysis (MICA)...
September 16, 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27648177/temporal-plus-epilepsy-anatomo-electroclinical-subtypes
#17
René Andrade-Machado, Vanessa Benjumea-Cuartas
Background: Mesial temporal lobe epilepsy (TLE) is a remediable epileptic syndrome. About 40% of patients continue to have seizures after standard temporal lobectomy. It has been suggested that some of these patients could actually suffer from a more complex epileptogenic network. Because a few papers have been dedicated to this topic, we decided to write an article updating this theme. Methods: We performed a literature search using the following terminology: "temporal plus epilepsy and networks," "temporal plus epilepsy," "orbito-temporal epilepsy," "temporo-insular epilepsy," "temporo-parieto-occipital (TPO) epilepsy," "parieto-temporal epilepsy," "intracortical evoked potential and temporal plus epilepsy," "temporal lobe connectivity and epilepsy," "intracortical evoked potential and epilepsy surgery," "role of extratemporal structures in TLE," "surgical failure after temporal lobectomy," "Diffusion tensor imaging (DTI) and temporal epilepsy," and "positron emission tomography (PET) in temporal plus lobe epilepsy" in the existing PubMed databases...
July 6, 2016: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/27635629/pre-ictal-bold-alterations-two-cases-of-patients-with-focal-epilepsy
#18
Sarah A Vinette, Shahleen Premji, Craig A Beers, Ismael Gaxiola-Valdez, Daniel J Pittman, Edward G Slone, Bradley G Goodyear, Paolo Federico
The pre-ictal state is of interest for better understanding pathophysiological processes leading up to seizures and for identifying potential biomarkers for the prediction of these events. We present two cases of patients with focal epilepsy (occipital, insular) who had seizures during functional magnetic resonance imaging (fMRI) scans. Interictal (>30min pre-seizure) control data was available for one participant. The location and timing of pre-ictal blood oxygenation-level dependent (BOLD) signal alterations were examined along with changes in pre-ictal functional connectivity...
September 8, 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27592471/retinotopic-fmri-and-tumour-resection-in-a-case-with-occipital-lobe-epilepsy
#19
Khalid Hamandi, Siân E Robson, Malek Zaben, Krish D Singh, William P Gray
No abstract text is available yet for this article.
October 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27554452/epilepsy-due-to-mutations-in-the-mitochondrial-polymerase-gamma-polg-gene-a-clinical-and-molecular-genetic-review
#20
Maria-Eleni Anagnostou, Yi Shiau Ng, Robert W Taylor, Robert McFarland
We performed a systematic review of the clinical, molecular, and biochemical features of polymerase gamma (POLG)-related epilepsy and current evidence on seizure management. Patients were identified from a combined electronic search of articles using Ovid Medline and Scopus databases, published from January 2000 to January 2015. Only patients with a confirmed genetic diagnosis of POLG mutations were considered. Seventy-two articles were included for analysis. We identified 128 pathogenic variants in 372 patients who had POLG-related epilepsy...
October 2016: Epilepsia
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