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Occipital epilepsy

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https://www.readbyqxmd.com/read/29351559/characterisation-of-ictal-and-interictal-states-of-epilepsy-a-system-dynamic-approach-of-principal-dynamic-modes-analysis
#1
Zabit Hameed, Saqib Saleem, Jawad Mirza, Muhammad Salman Mustafa, Qamar-Ul-Islam
Epilepsy is a brain disorder characterised by the recurrent and unpredictable interruptions of normal brain function, called epileptic seizures. The present study attempts to derive new diagnostic indices which may delineate between ictal and interictal states of epilepsy. To achieve this, the nonlinear modeling approach of global principal dynamic modes (PDMs) is adopted to examine the functional connectivity of the temporal and frontal lobes with the occipital brain segment using an ensemble of paediatric EEGs having the presence of epileptic seizure...
2018: PloS One
https://www.readbyqxmd.com/read/29295522/comparison-between-scalp-eeg-and-behind-the-ear-eeg-for-development-of-a-wearable-seizure-detection-system-for-patients-with-focal-epilepsy
#2
Ying Gu, Evy Cleeren, Jonathan Dan, Kasper Claes, Wim Van Paesschen, Sabine Van Huffel, Borbála Hunyadi
A wearable electroencephalogram (EEG) device for continuous monitoring of patients suffering from epilepsy would provide valuable information for the management of the disease. Currently no EEG setup is small and unobtrusive enough to be used in daily life. Recording behind the ear could prove to be a solution to a wearable EEG setup. This article examines the feasibility of recording epileptic EEG from behind the ear. It is achieved by comparison with scalp EEG recordings. Traditional scalp EEG and behind-the-ear EEG were simultaneously acquired from 12 patients with temporal, parietal, or occipital lobe epilepsy...
December 23, 2017: Sensors
https://www.readbyqxmd.com/read/29285091/treatment-of-acute-intermittent-porphyria-during-pregnancy-and-posterior-reversible-encephalopathy-syndrome-after-delivery-a-case-report
#3
Jian Zhang, Yiting Hu, Jimin Zheng, Juncha Gao, Hongtao Hou, Na Liu, Yuzhen Wang
Acute intermittent porphyria (AIP) is a rare inherited disorder of heme metabolism. It has the ability to trigger posterior reversible encephalopathy syndrome (PRES), a rare acute neurologic condition that is characterized by acute neurological symptoms. Pregnancy may induce AIP attacks. The present report describes the case of a pregnant woman with AIP. The patient was treated with heme-arginate during pregnancy and successfully delivered a healthy baby. Following delivery, the patient presented with PRES and experienced generalized seizures...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29274110/metabolic-correlates-of-cognitive-function-in-children-with-unilateral-sturge-weber-syndrome-evidence-for-regional-functional-reorganization-and-crowding
#4
Jeong-A Kim, Jeong-Won Jeong, Michael E Behen, Vinod K Pilli, Aimee Luat, Harry T Chugani, Csaba Juhász
To evaluate metabolic changes in the ipsi- and contralateral hemisphere in children showing a cognitive profile consistent with early reorganization of cognitive function, we evaluated the regional glucose uptake, interhemispheric metabolic connectivity, and cognitive function in children with unilateral SWS. Interictal 2-deoxy-2[18 F]fluoro-D-glucose (FDG)-PET scans of 27 children with unilateral SWS and mild epilepsy and 27 age-matched control (non-SWS children with epilepsy and normal FDG-PET) were compared using statistical parametric mapping (SPM)...
December 23, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29260614/neuroimaging-findings-in-pallister-killian-syndrome
#5
Emil Jernstedt Barkovich, Tarannum Musvee Lateef, Matthew T Whitehead
Pallister-Killian syndrome (PKS) is a rare chromosomal duplication disorder caused by additional copies of the short arm of chromosome 12 (12p). Clinically PKS is characterized by craniofacial dysmorphism with neonatal frontotemporal alopecia, hypertelorism, and low-set ears as well as kyphoscoliosis, severe intellectual disability, epilepsy, and abnormal muscle tone. Comprehensive high-resolution brain MR findings of PKS in childhood have not been previously illustrated in the medical literature. We present detailed neuroimaging findings from a child with PKS and thoroughly review previously reported structural brain abnormalities in this patient population...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29260011/isolated-pons-involvement-in-posterior-reversible-encephalopathy-syndrome-case-report-and-review-of-the-literature
#6
REVIEW
Mariangela Ferrara, Pietro Di Viesti, Vincenzo Inchingolo, Raffaela Rita Latino, Teresa Popolizio, Salvatore Angelo De Cosmo, Flavia Pugliese, Maurizio Angelo Leone
Background: Posterior Reversible Encephalopathy Syndrome (PRES) is a clinical-radiological syndrome, usually reversible and with a favorable prognosis, which recognizes a variety of etiologies and clinical patterns and is likely due to an impairment in cerebral blood flow autoregulation. It is typically characterized by subcortical, predominantly parieto-occipital, vasogenic brain oedema in patients with acute-subacute neurological symptoms. Infratentorial oedema on neuroimaging has been mostly described in association with the typical supratentorial pattern and seldom as isolated...
March 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29258967/occipital-ulegyria-causing-epilepsy-and-visual-impairment-an-easily-overlooked-epilepsy-syndrome
#7
Antoinette O'Connor, Daniel J Costello
Ulegyria refers to scarring of the cerebral cortex usually arising from perinatal ischaemia. The scarring has a specific configuration in which small atrophic circumvolutions at the bottom of a sulcus underlie an intact spared gyral apex. This disconnection of overlying cortex may allow an "epileptogenic" island of cortex to generate seizures. Ulegyria is often associated with epilepsy and developmental delay, however, the syndromic association of visual impairment with epilepsy due to occipital ulegyria may not be recognised as a specific entity...
December 20, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29247375/a-novel-mutation-in-lamc3-associated-with-generalized-polymicrogyria-of-the-cortex-and-epilepsy
#8
J L Zambonin, D A Dyment, Y Xi, R E Lamont, T Hartley, E Miller, M Kerr, K M Boycott, J S Parboosingh, S Venkateswaran
Occipital cortical malformation is a rare neurodevelopmental disorder characterized by pachygyria and polymicrogyria of the occipital lobes as well as global developmental delays and seizures. This condition is due to biallelic, loss-of-function mutations in LAMC3 and has been reported in four unrelated families to date. We report an individual with global delays, seizures, and polymicrogyria that extends beyond the occipital lobes and includes the frontal, parietal, temporal, and occipital lobes. Next-generation sequencing identified a homozygous nonsense mutation in LAMC3: c...
December 15, 2017: Neurogenetics
https://www.readbyqxmd.com/read/29219756/awake-perimetry-testing-for-occipital-epilepsy-surgery
#9
Holger Joswig, John P Girvin, Warren T Blume, Jorge G Burneo, David A Steven
In the literature, there are few reports that provide a detailed account on the technique of visual electrocortical stimulation in the setting of resective surgery for occipital epilepsy. In this technical note, the authors describe how a 26-year-old male with long-standing occipital epilepsy underwent resective surgery under awake conditions, using electrocortical stimulation of the occipital lobe, with the aid of a laser pointer and a perimetry chart on a stand within his visual field. The eloquent primary visual cortex was found to overlap with the seizure onset zone that was previously determined with subdural electrodes...
December 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29190524/four-dimensional-map-of-the-human-early-visual-system
#10
Yasuo Nakai, Akari Nagashima, Akane Hayakawa, Takuya Osuki, Jeong-Won Jeong, Ayaka Sugiura, Erik C Brown, Eishi Asano
OBJECTIVE: We generated a large-scale, four-dimensional map of neuronal modulations elicited by full-field flash stimulation. METHODS: We analyzed electrocorticography (ECoG) recordings from 63 patients with focal epilepsy, and delineated the spatial-temporal dynamics of visually-elicited high-gamma70-110 Hz amplitudes on a standard brain template. We then clarified the neuronal events underlying visual evoked potential (VEP) components, by correlating with high-gamma amplitude measures...
November 27, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29171397/crossing-the-lines-between-epilepsy-syndromes-a-myoclonic-epilepsy-variant-with-prominent-eyelid-myoclonia-and-atonic-components
#11
Pinelopi Dragoumi, Jacqueline Emery, Fiona Chivers, Megan Brady, Archana Desurkar, J Helen Cross, Krishna B Das
Accurate diagnosis of a distinct epilepsy syndrome is based on well-defined electroclinical features that differentiate separate nosological entities. In clinical practice, however, syndromes may overlap and cases may present with unusual manifestations posing a diagnostic challenge. This heterogeneity has been documented in several cases presenting with eyelid myoclonia with or without absences (EMA) diagnosed either as Jeavons syndrome (JS) variants or as genetic generalised epilepsies defined by the presence of this unique clinical entity...
November 24, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29166136/the-gamma-aminobutyric-acid-b-receptor-gabab-encephalitis-clinical-manifestations-and-response-to-immunotherapy
#12
Junzhao Cui, Hui Bu, Junying He, Zeyan Zhao, Weixin Han, Ruiping Gao, Xiaoqing Li, Qing Li, Xiaosu Guo, Yueli Zou
PURPOSE: We report 11 patients diagnosed with GABAB receptor (GABABR) antibodies encephalitis in China and aim to analyze the clinical characteristics, laboratory and imaging findings, therapeutic modalities and outcomes. METHODS: Clinical data from patients diagnosed with anti-GABAB receptor encephalitis in the Second Affiliated Hospital of Hebei Medical University from February 2016 to October 2016 January were retrospectively collected and evaluated. RESULTS: Of the 11 patients, seven were males, and a mean age at presentation of 63 years (range: 47-79 years)...
December 6, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29140463/anatomic-investigation-of-the-trajectory-for-stereotactic-laser-amygdalohippocampectomy
#13
Vanessa M Holanda, Abuzer Gungor, Serhat Baydin, Erik H Middlebrooks, Shabbar F Danish
BACKGROUND: Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) has emerged as a promising treatment for mesial temporal lobe epilepsy. Surgeons must understand the relevant anatomy that is traversed by the catheter and affected by ablation. OBJECTIVE: To study the anatomic structures crossed by the LITT catheter until it reaches the amygdala. METHODS: Three human cadaveric heads were implanted with catheters using a frameless stereotactic technique...
November 11, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29122895/migration-of-ventriculoperitoneal-shunt-to-urethral-and-rectal-orifices
#14
Banan Osman, Stella Roushias, Rachel Hargest, Krishna Narahari
Ventriculoperitoneal (VP) shunt surgery remains the most widely used neurosurgical procedure for the management of hydrocephalus. However, shunt complications are common and may require multiple surgical procedures during a patient's lifetime. We report the case of a 29-year-old patient with a background of Dandy-Walker malformation, occipital encephalocele, recurrent hydrocephalus, spina bifida and epilepsy presented with VP shunt migration into urinary and gastrointestinal tracts. In absence of sepsis or peritonism from either bowel or bladder perforation, local control of stent extrusion was successful for several years, although surgery was eventually undertaken...
November 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29076788/relationship-between-cortical-resection-and-visual-function-after-occipital-lobe-epilepsy-surgery
#15
Won Heo, June Sic Kim, Chun Kee Chung, Sang Kun Lee
OBJECTIVE In this study, the authors investigated long-term clinical and visual outcomes of patients after occipital lobe epilepsy (OLE) surgery and analyzed the relationship between visual cortical resection and visual function after OLE surgery. METHODS A total of 42 consecutive patients who were diagnosed with OLE and underwent occipital lobe resection between June 1995 and November 2013 were included. Clinical, radiological, and histopathological data were reviewed retrospectively. Seizure outcomes were categorized according to the Engel classification...
October 27, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29064616/gain-of-function-hcn2-variants-in-genetic-epilepsy
#16
Melody Li, Snezana Maljevic, A Marie Phillips, Slave Petrovski, Michael Hildebrand, Rosemary Burgess, Therese Mount, Federico Zara, Pasquale Striano, Julian Schubert, Holger Thiele, Peter Nürnberg, Michael Wong, Judith L Weisenberg, Liu Lin Thio, Holger Lerche, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou, Christopher A Reid
Genetic generalized epilepsy (GGE) is a common epilepsy syndrome that encompasses seizure disorders characterized by spike-and-wave discharges (SWDs). Pacemaker hyperpolarization-activated cyclic nucleotide-gated channels (HCN) are considered integral to SWD genesis, making them an ideal gene candidate for GGE. We identified HCN2 missense variants from a large cohort of 585 GGE patients, recruited by the Epilepsy Phenome-Genome Project (EPGP), and performed functional analysis using two-electrode voltage clamp recordings from Xenopus oocytes...
October 24, 2017: Human Mutation
https://www.readbyqxmd.com/read/29062689/occipital-dysembryoplastic-neuroepithelial-tumor-presenting-as-adult-onset-temporal-epilepsy
#17
Riddhi Patira, Cody Nathan, Sarah Zubkov, Camilo Gutierrez, Charles Munyon, Abir Mukherjee, Mercedes Jacobson
Dysembryoplastic neuroepithelial tumor (DNET) is a benign brain tumor which commonly presents as childhood-onset temporal lobe epilepsy (TLE). We present a case of histologically proven DNET with a clinical presentation and scalp EEG suggestive of adult-onset TLE. MRI showed an occipital lesion. PET showed abnormal metabolism of the occipital lesion and the ipsilateral temporal lobe; raising concern for an abnormal functional network reorganization. Intracranial EEG showed interictal spikes and seizures originating from the occipital lesion with no seizures emanating from the temporal lobe...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29060677/localization-of-stereo-electroencephalography-signals-using-a-finite-difference-complete-electrode-model
#18
Damon E Hyde, Xavier Tomas-Fernandez, Scellig S Stone, Jurriaan Peters, Simon K Warfield
Surgical intervention in epilepsy aims to eliminate seizures in refractory patients by resecting the tissue responsible for seizure onset. Stereo-electroencephalography (sEEG) provides highly accurate but invasive electrophysiological measurements using narrow multi-contact electrodes implanted stereotactically through small holes in the skull. However, the three dimensional nature of sEEG measurements make observed seizure onsets difficult to associate with physical cortical regions. Three dimensional source localization from sEEG measurements can improve the interpretation of this data, but requires more accurate modeling as compared to localization from scalp EEG...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28993753/electroencephalography-in-the-diagnosis-of-genetic-generalized-epilepsy-syndromes
#19
REVIEW
Udaya Seneviratne, Mark J Cook, Wendyl Jude D'Souza
Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized spike-wave complex. Other classic EEG abnormalities are polyspikes, epileptiform K-complexes and sleep spindles, polyspike-wave discharges, occipital intermittent rhythmic delta activity, eye-closure sensitivity, fixation-off sensitivity, and photoparoxysmal response...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28963933/functional-surgery-in-pediatric-drug-resistant-posterior-cortex-epilepsy-electro-clinical-findings-cognitive-and-seizure-outcome
#20
A Sierra-Marcos, M C Fournier-Del Castillo, J Álvarez-Linera, M Budke, M García-Fernández, M A Pérez-Jiménez
PURPOSE: Epilepsies originated from the occipital, parietal and/or the posterior edge of the temporal lobe are grouped together into posterior cortex epilepsy (PCE). Our objective was firstly to describe electro-clinical and imaging findings in the presurgical evaluation of children with PCE, and secondly to identify potential factors associated with surgical and cognitive outcomes. METHOD: From the total of patients referred to the Epilepsy Monitoring Unit of 'Hospital Universitario Niño Jesús' from 2003 to 2016, 55 had drug-resistant PCE...
September 22, 2017: Seizure: the Journal of the British Epilepsy Association
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