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https://www.readbyqxmd.com/read/28407646/assessing-the-performance-of-3-human-immunodeficiency-virus-incidence-risk-scores-in-a-cohort-of-black-and-white-men-who-have-sex-with-men-in-the-south
#1
Jeb Jones, Martin Hoenigl, Aaron J Siegler, Patrick S Sullivan, Susan Little, Eli Rosenberg
BACKGROUND: Risk scores have been developed to identify men at high risk of human immunodeficiency virus (HIV) seroconversion. These scores can be used to more efficiently allocate public health prevention resources, such as pre-exposure prophylaxis. However, the published scores were developed with data sets that comprise predominantly white men who have sex with men (MSM) collected several years prior and recruited from a limited geographic area. Thus, it is unclear how well these scores perform in men of different races or ethnicities or men in different geographic regions...
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28407644/mobile-phone-and-internet-use-mostly-for-sex-seeking-and-associations-with-sexually-transmitted-infections-and-sample-characteristics-among-black-african-american-and-hispanic-latino-men-who-have-sex-with-men-in-3-us-cities
#2
Jacob E Allen, Gordon Mansergh, Matthew J Mimiaga, Jeremy Holman, Jeffrey H Herbst
BACKGROUND: Men who have sex with men (MSM) have a relatively high prevalence of sexually transmitted infections (STIs). This study examines the association of self-reported STIs and use of mobile phones and/or computer-based Internet to meet sexual partners among black and Hispanic/Latino MSM in the United States. METHODS: Black and Hispanic/Latino MSM (N = 853) were recruited from 3 US cities (Chicago, IL; Kansas City, MO; and Fort Lauderdale, FL) via online and community outreach...
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28406271/the-relationship-between-higher-social-trust-and-lower-late-hiv-diagnosis-and-mortality-differs-by-race-ethnicity-results-from-a-state-level-analysis
#3
Yusuf Ransome, Ashley Batson, Sandro Galea, Ichiro Kawachi, Denis Nash, Kenneth H Mayer
INTRODUCTION: Black men who have sex with men (MSM) continue to suffer a disproportionate burden of new HIV diagnoses and mortality. To better understand some of the reasons for these profound disparities, we examined whether the association between social trust and late HIV diagnosis and mortality differed by race/ethnicity, and investigated potential indirect effects of any observed differences. METHODS: We performed generalized structural equation modelling to assess main and interaction associations between trust among one's neighbours in 2009 (i...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28404766/randomised-controlled-trial-of-a-sexual-risk-reduction-intervention-for-sti-prevention-among-men-who-have-sex-with-men-in-the-usa
#4
Lisa A Eaton, Seth C Kalichman, Moira O Kalichman, Daniel D Driffin, Robert Baldwin, Larissa Zohren, Christopher Conway-Washington
OBJECTIVES: Novel interventions to address sexual risk taking and slow rates of STIs are urgently needed, in particular among black men who have sex with men (MSM) in the USA. Serosorting, or limiting condomless sex acts to partners of the same HIV status, is commonly practised among MSM, yet can lead to STI and remains largely unaddressed by public health agencies. METHODS: A two-arm, randomised controlled trial was conducted from 2012 to 2015. This trial assessed the effects of a single-session, sexual partner selection and risk decision intervention (experimental arm) versus a single-session, Centers for Disease Control and Prevention-based, sexual risk reduction intervention (control arm) on psychosocial measures, sexual risk taking and STI...
April 12, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28402405/sexual-networks-dyadic-characteristics-and-hiv-acquisition-and-transmission-behaviors-among-black-men-who-have-sex-with-men-in-6-us-cities
#5
DeMarc A Hickson, Leandro A Mena, Leo Wilton, Hong-Van Tieu, Beryl A Koblin, Vanessa Cummings, Carl Latkin, Kenneth H Mayer
The role of sexual networks in the epidemiology of human immunodeficiency virus (HIV) among black men who have sex with men (MSM) is poorly understood. Using data from 1,306 black MSM in the BROTHERS Study (2009-2010) in the United States, we examined the relationships between multiple sexual dyadic characteristics and serodiscordant/serostatus-unknown condomless sex (SDCS). HIV-infected participants had higher odds of SDCS when having sex at least weekly (odds ratio (OR) = 2.41, 95% confidence interval (CI): 1...
April 10, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28400851/what-influences-quality-of-life-in-older-people-living-with-hiv
#6
Jose Catalan, Veronica Tuffrey, Damien Ridge, Dana Rosenfeld
BACKGROUND: People with HIV with access to treatment are growing older and living healthier lives than in the past, and while health improvements and increased survival rates are welcome, the psychological and social consequences and quality of life of ageing are complex for this group. Understanding how ageing, HIV and quality of life intersect is key to developing effective interventions to improve QoL. METHODS: One hundred people with HIV over the age of 50 (range 50-87, mean 58), were recruited through HIV community organizations, and clinics, and included men who have sex with men (MSM), and Black African and White heterosexual men and women...
2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28399891/what-influences-quality-of-life-in-older-people-living-with-hiv
#7
Jose Catalan, Veronica Tuffrey, Damien Ridge, Dana Rosenfeld
BACKGROUND: People with HIV with access to treatment are growing older and living healthier lives than in the past, and while health improvements and increased survival rates are welcome, the psychological and social consequences and quality of life of ageing are complex for this group. Understanding how ageing, HIV and quality of life intersect is key to developing effective interventions to improve QoL. METHODS: One hundred people with HIV over the age of 50 (range 50-87, mean 58), were recruited through HIV community organizations, and clinics, and included men who have sex with men (MSM), and Black African and White heterosexual men and women...
April 11, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28398775/lack-of-support-for-socially-connected-hiv-1-transmission-among-young-adult-black-men-who-have-sex-with-men
#8
Kayo Fujimoto, Lyndon M Coghill, Christopher A Weier, Lu-Yu Hwang, Ju Yeong Kim, John A Schneider, Michael L Metzker, Jeremy M Brown
We explore the phylogenetic relationships among HIV sequences sampled from young adult black men who have sex with men (YAB-MSM), who are connected through peer referral/social ties and who attend common venues. Using 196 viral sequences sampled from the peripheral blood mononuclear cells of 10 individuals, our preliminary phylogenetic results indicate that these socially connected YAB-MSM are infected with distantly related viruses and provide no evidence for viral transmission between network members. Our results suggest that HIV-prevention strategies that target young adult MSM should extend beyond their network members and local community...
April 18, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28384058/analysis-of-hiv-integrase-resistance-in-black-men-who-have-sex-with-men-in-the-united-states
#9
Iris Chen, Yinfeng Zhang, Vanessa Cummings, Gavin A Cloherty, Matthew Connor, Geetha Beauchamp, Sam Griffith, Scott Rose, Joel Gallant, Hyman M Scott, Steven Shoptaw, Carlos Del Rio, Irene Kuo, Sharon Mannheimer, Hong-Van Tieu, Christopher B Hurt, Sheldon D Fields, Darrell P Wheeler, Kenneth H Mayer, Beryl A Koblin, Susan H Eshleman
Resistance to reverse transcriptase and protease inhibitors was frequently detected in HIV from black men who have sex with men (MSM) enrolled in the HIV prevention trials network (HPTN) 061 study. In this study, integrase strand transfer inhibitor (INSTI) resistance was analyzed in black MSM enrolled in HPTN 061 (134 infected at enrollment and 23 seroconverters) and a follow-up study, HPTN 073 (eight seroconverters). The ViroSeq HIV-1 Integrase Genotyping Kit (Abbott Molecular) was used for analysis. Major INSTI resistance mutations were not detected in any of the samples...
April 6, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28368523/the-continuum-of-hiv-care-in-the-urban-united-states-black-men-who-have-sex-with-men-msm-are-less-likely-than-white-msm-to-receive-antiretroviral-therapy
#10
Sten H Vermund
No abstract text is available yet for this article.
March 29, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28368493/updated-data-on-linkage-to-human-immunodeficiency-virus-care-and-antiretroviral-treatment-among-men-who-have-sex-with-men-20-cities-united-states
#11
Brooke E Hoots, Teresa J Finlayson, Cyprian Wejnert, Gabriela Paz-Bailey
We examined differences in prevalence of linkage to care and antiretroviral (ARV) treatment among human immunodeficiency virus (HIV)-positive men who have sex with men (MSM) between 2008 and 2014 in National HIV Behavioral Surveillance. Prevalence of linkage to care increased from 79% in 2008 to 87% in 2014 (prevalence ratio [PR], 1.05; 95% confidence interval [CI], 1.03-1.07). ARV treatment increased from 69% in 2008 to 88% in 2014 (adjusted PR, 1.15; 95% CI, 1.12-1.18). Despite these increases, a large disparity in ARV treatment between white and black MSM remains...
March 29, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28346077/effects-of-brief-messages-about-antiretroviral-therapy-and-condom-use-benefits-among-black-and-latino-msm-in-three-us-cities
#12
Jeffrey H Herbst, Gordon Mansergh, Nicole Pitts, Damian Denson, Matthew J Mimiaga, Jeremy Holman
This pilot study examined effects of HIV prevention messages about self and partner benefits of antiretroviral therapy (ART) and condom effectiveness on increased intentions for behavior change. Data were from Messages4Men, a study examining prevention messages among 320 HIV-positive and 605 HIV-negative black and Latino MSM. Men completed a computer-based assessment after message exposure, and multivariable models controlled for risky sex and demographics. A majority of HIV-positive men reported increased intentions for ART use; 22% reported partner benefit information was new...
March 27, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28336355/estimated-hiv-inter-test-interval-among-people-at-high-risk-for-hiv-infection-in-the-u-s
#13
Qian An, Ruiguang Song, Teresa J Finlayson, Cyprian Wejnert, Gabriela Paz-Bailey
INTRODUCTION: Knowing the HIV testing frequency and its temporal changes are central to evaluate public adherence to HIV testing recommendations and performance of HIV prevention programs. This study intended to estimate the mean HIV inter-test interval (ITI) and monitor its trends among men who have sex with men (MSM); people who inject drugs (PWID); and high-risk heterosexuals (HRH). METHODS: Using National HIV Behavioral Surveillance data collected during 2008-2015, this analysis estimated the mean HIV ITI for each year by race/ethnicity and age among MSM, PWID, and HRH who reported the most recent HIV test date...
March 20, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28332090/disparities-in-the-clinical-evolution-of-anal-neoplasia-in-an-hiv-infected-cohort
#14
Edward R Cachay, Wollelaw Agmas, Wm Christopher Mathews
BACKGROUND: A recent meta-analysis suggested that anal intraepithelial neoplasia and invasive anal cancer are more prevalent among black men having sex with men (MSM). METHODS: We conducted a retrospective cohort of HIV-infected adult patients under care between 2001 and 2012. Disparities in clinical evolution of anal intraepithelial neoplasia to high-grade squamous intraepithelial lesion (HSIL) and invasive anal cancer were evaluated in a three-state Markov model adjusted for cytology misclassification...
March 23, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28286983/stigma-medical-mistrust-and-perceived-racism-may-affect-prep-awareness-and-uptake-in-black-compared-to-white-gay-and-bisexual-men-in-jackson-mississippi-and-boston-massachusetts
#15
Sean Cahill, S Wade Taylor, Steven A Elsesser, Leandro Mena, DeMarc Hickson, Kenneth H Mayer
Gay and bisexual men and other men who have sex with men (MSM) account for more than two thirds of new HIV infections in the U.S., with Black MSM experiencing the greatest burden. Antiretroviral pre-exposure prophylaxis (PrEP) can reduce MSM's vulnerability to HIV infection. Uptake of PrEP has been limited, particularly among racial and ethnic minority MSM. Four semi-structured focus groups with gay and bisexual men and other MSM at risk for HIV infection were convened in Boston and Jackson in late 2013. The analysis plan utilized a within-case, across-case approach to code and analyze emerging themes, and to compare results across the two cities...
March 12, 2017: AIDS Care
https://www.readbyqxmd.com/read/28282649/emerging-regional-and-racial-disparities-in-the-lifetime-risk-of-human-immunodeficiency-virus-infection-among-men-who-have-sex-with-men-a-comparative-life-table-analysis-in-king-county-wa-and-mississippi
#16
Galant A Chan, Kendra L Johnson, Nicholas G Mosca, Thomas E Dobbs, Julia C Dombrowski, Amy B Bennett, Susan E Buskin, Matthew R Golden
BACKGROUND: Little is known about the lifetime risk of human immunodeficiency virus (HIV) diagnosis among US men who have sex with men (MSM), trends in risk and how risk varies between populations. METHODS: We used census and HIV surveillance data to construct life tables to estimate the cumulative risk of HIV diagnosis among cohorts of MSM born 1940 to 1994 in King County, Washington (KC) and Mississippi (MS). RESULTS: The cumulative risk of HIV diagnosis progressed in 3 phases...
April 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28260636/hiv-risk-behaviours-among-immigrant-and-ethnic-minority-gay-and-bisexual-men-in-north-america-and-europe-a-systematic-review
#17
Nathaniel M Lewis, Kathi Wilson
HIV surveillance systems show that gay, bisexual, and other men who have sex with men (MSM) bear a disproportionate burden of HIV in North American and European countries. Within the MSM category, HIV prevalence is often elevated among ethnic minority (i.e., Latino, Asian, and Black) MSM, many of whom are also foreign-born immigrants. Little research has focused specifically on foreign-born populations, though studies that provide data on the nativity of their samples offer an opportunity to investigate the potential role of transnational migration in informing HIV risk among ethnic minority MSM...
February 24, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28224313/sexual-stereotypes-ascribed-to-black-men-who-have-sex-with-men-an-intersectional-analysis
#18
Sarah K Calabrese, Valerie A Earnshaw, Manya Magnus, Nathan B Hansen, Douglas S Krakower, Kristen Underhill, Kenneth H Mayer, Trace S Kershaw, Joseph R Betancourt, John F Dovidio
Sexual stereotypes may adversely affect the health of Black men who have sex with men (MSM). Greater understanding of the nature and nuances of these stereotypes is needed. This online, survey-based study used an inductive, intersectional approach to characterize the sexual stereotypes ascribed to Black MSM by the U.S. general public, their distinctiveness from those ascribed to Black men and MSM in general, and their relative prototypicality as compared to dominant subgroups. Members of the public, recruited in 2014-2015, were randomly assigned to survey conditions that varied systematically by race (Black, White, or unspecified) and sexual orientation (gay, heterosexual, or unspecified) of a designated social group...
February 21, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28195201/crispr-cas9-mediated-genome-editing-in-wild-derived-mice-generation-of-tamed-wild-derived-strains-by-mutation-of-the-a-nonagouti-gene
#19
Michiko Hirose, Ayumi Hasegawa, Keiji Mochida, Shogo Matoba, Yuki Hatanaka, Kimiko Inoue, Tatsuhiko Goto, Hideki Kaneda, Ikuko Yamada, Tamio Furuse, Kuniya Abe, Yoshihisa Uenoyama, Hiroko Tsukamura, Shigeharu Wakana, Arata Honda, Atsuo Ogura
Wild-derived mice have contributed to experimental mouse genetics by virtue of their genetic diversity, which may help increase the chance of identifying novel modifier genes responsible for specific phenotypes and diseases. However, gene targeting using wild-derived mice has been unsuccessful because of the unavailability of stable embryonic stem cells. Here, we report that CRISPR/Cas9-mediated gene targeting can be applied to the Japanese wild-derived MSM/Ms strain (Mus musculus molossinus). We targeted the nonagouti (a) gene encoding the agouti protein that is localized in hair and the brain...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28159730/hiv-trends-in-the-united-states-diagnoses-and-estimated-incidence
#20
H Irene Hall, Ruiguang Song, Tian Tang, Qian An, Joseph Prejean, Patricia Dietz, Angela L Hernandez, Timothy Green, Norma Harris, Eugene McCray, Jonathan Mermin
BACKGROUND: The best indicator of the impact of human immunodeficiency virus (HIV) prevention programs is the incidence of infection; however, HIV is a chronic infection and HIV diagnoses may include infections that occurred years before diagnosis. Alternative methods to estimate incidence use diagnoses, stage of disease, and laboratory assays of infection recency. Using a consistent, accurate method would allow for timely interpretation of HIV trends. OBJECTIVE: The objective of our study was to assess the recent progress toward reducing HIV infections in the United States overall and among selected population segments with available incidence estimation methods...
February 3, 2017: JMIR Public Health and Surveillance
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