Shanaz M Daneshdoost, Jad M El Abiad, Kathy J Ruble, Lynne C Jones, Janet L Crane, Carol D Morris, Adam S Levin
BACKGROUND: Despite improved outcomes in children with leukemia, complications such as osteonecrosis are common. We conducted a systematic review to investigate the role of bisphosphonates in reducing pain, improving mobility, and stabilizing lesions in pediatric leukemia survivors. METHODS: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched the PubMed, Embase, Cochrane, Web of Science, Scopus, CINAHL, and ClinicalTrials...
April 1, 2021: Journal of Pediatric Hematology/oncology