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Chia-Hua Tai, Mei-Yu Hsu
BACKGROUND: Noninvasive positive pressure ventilation (NPPV) provides ventilation without tracheal intubation. Facial pressure injury is a recognized complication of this technique, making the prevention of facial pressure injuries an important issue for NPPV patients. PURPOSE: The present study compared the effects of foam dressing and hydrocolloid dressing in preventing facial pressure injuries in NPPV patients. METHODS: A randomized clinical trial was used to evaluate participants that were referred from the intensive care unit of a medical center in eastern Taiwan...
October 2016: Hu Li za Zhi the Journal of Nursing
Steven Kwasi Korang, Joshua Feinberg, Jørn Wetterslev, Janus C Jakobsen
BACKGROUND: Asthma is one of the most common reasons for hospital admission among children and constitutes a significant economic burden. Use of non-invasive positive pressure ventilation (NPPV) in the care of children with acute asthma has increased even though evidence supporting the intervention has been considered weak and clinical guidelines do not recommend the intervention. NPPV might be an effective intervention for acute asthma, but no systematic review has been conducted to assess the effects of NPPV as an add-on therapy to usual care in children with acute asthma...
September 30, 2016: Cochrane Database of Systematic Reviews
Lu-Qian Zhou, Xiao-Ying Li, Yun Li, Bing-Peng Guo, Li-Li Guan, Xin Chen, Yu-Wen Luo, Peng Luo, Rong-Chang Chen
OBJECTIVE: To investigate the effects of inspiratory muscle training followed by non-invasive positive pressure ventilation in patients with severe chronic obstructive pulmonary disease (COPD). METHODS: This investigator-initiated randomized, controlled trial recruited 88 patients with stable GOLD stage IV COPD, who were randomized into 4 equal groups to continue oxygen therapy (control group) or to receive inspiratory muscle training followed by non-invasive positive pressure ventilation (IMT-NPPV group), inspiratory muscle training only (IMT group), or noninvasive positive pressure ventilation only (NPPV group) for at least 8 weeks...
August 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Yi Yang, Nan Liu, Lizhong Sun, Ye Zhou, Yong Yang, Wei Shang, Xiaomi Li
OBJECTIVES: To assess the efficacy of noninvasive positive-pressure ventilation (NPPV) in improving hypoxemia after extubation for Stanford type-A aortic dissection and to compare NPPV using a mask or a helmet. DESIGN: Prospective, interventional study. SETTING: Department of Cardiac Surgery of the Beijing Anzhen Hospital, a tertiary university hospital. PARTICIPANTS: Patients experiencing hypoxemia within 24 hours after extubation for Stanford type-A aortic dissection...
March 10, 2016: Journal of Cardiothoracic and Vascular Anesthesia
Jing Cheng, Yanping Liu, Guishuang Li, Zhongwen Zhang, Lianyue Ma, Xiaoyan Yang, Jianmin Yang, Kai Zhang, Jing Kong, Mei Dong, Meng Zhang, Xingli Xu, Wenhai Sui, Jiali Wang, Rui Shang, Xiaoping Ji, Yun Zhang, Cheng Zhang, Panpan Hao
Chronic heart failure (CHF) has been shown to be associated with an increased incidence of sleep-disordered breathing. Whether treatment with noninvasivepositive-pressure ventilation (NPPV), including continuous positive airway pressure, bi-level positive airway pressure and adaptive servo-ventilation, improves clinical outcomes of CHF patients is still debated. 2,832 CHF patients were enrolled in our analysis. NPPV was significantly associated with improvement in left ventricular ejection fraction (39.39% vs...
July 6, 2016: Oncotarget
Audun Eskeland Rimehaug, Ingrid Elise Hoff, Lars Øivind Høiseth, Jonny Hisdal, Petter Aadahl, Idar Kirkeby-Garstad
BACKGROUND: Changes in cardiac power parameters incorporate changes in both aortic flow and blood pressure. We hypothesized that dynamic and non-dynamic cardiac power parameters would track hypovolemia better than equivalent flow- and pressure parameters, both during spontaneous breathing and non-invasive positive pressure ventilation (NPPV). METHODS: Fourteen healthy volunteers underwent lower body negative pressure (LBNP) of 0, -20, -40, -60 and -80 mmHg to simulate hypovolemia, both during spontaneous breathing and during NPPV...
2016: BMC Anesthesiology
Yusuke Fujiwara, Hiroki Yamaguchi, Katsuya Kobayashi, Atsushi Marumo, Ikuko Omori, Satoshi Yamanaka, Shunsuke Yui, Keiko Fukunaga, Takeshi Ryotokuji, Tsuneaki Hirakawa, Masahiro Okabe, Satoshi Wakita, Hayato Tamai, Muneo Okamoto, Kazutaka Nakayama, Shinhiro Takeda, Koiti Inokuchi
Objective In hematological malignancy patients, the complication of acute respiratory failure often reaches a degree of severity that necessitates mechanical ventilation. The objective of the present study was to investigate the therapeutic outcomes of mechanical ventilation in hematological malignancy patients with respiratory failure and to analyze the factors that are associated with successful treatment in order to identify the issues that should be addressed in the future. Methods The present study was a retrospective analysis of 71 hematological malignancy patients with non-cardiogenic acute respiratory failure who were treated with mechanical ventilation at Nippon Medical School Hospital between 2003 and 2014...
2016: Internal Medicine
Deanna Britton, Joshua O Benditt, Jeannette D Hoit
For more than a decade, there has been a trend toward increased use of noninvasive positive pressure ventilation (NPPV) via mask or mouthpiece as a means to provide ventilatory support without the need for tracheostomy. All indications are that use of NPPV will continue to increase over the next decade and beyond. In this article, we review NPPV, describe two common forms of NPPV, and discuss the potential benefits and challenges of NPPV for speaking and swallowing based on the available literature, our collective clinical experience, and interviews with NPPV users...
August 2016: Seminars in Speech and Language
Takamitsu Kawazu, Takeshi Nakamura, Takashi Moriki, Yoshi-Ichiro Kamijo, Yukihide Nishimura, Tokio Kinoshita, Fumihiro Tajima
BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been implicated in enhancing neuronal health. Exercise and noninvasive-positive-pressure-ventilation (NPPV) are known to independently alter BDNF levels in patients with depression, dementia, type 2 diabetes, chronic obstructive pulmonary disease and obstructive sleep apnea syndrome. However, the combined effects of exercise and NPPV on serum BDNF in normal subjects are unknown. OBJECTIVE: To determine the effects of the combination of acute aerobic exercise under NPPV on serum BDNF in normal adults...
May 18, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Toru Kadowaki, Kiryo Wakabayashi, Masahiro Kimura, Kanako Kobayashi, Toshikazu Ikeda, Shuichi Yano
BACKGROUND: For patients with chronic respiratory failure (CRF) who are treated with noninvasive positive pressure ventilation (NPPV), a little is known regarding the effects of low-intensity NPPV (LI-NPPV) on the clinical course of CRF and the frequency of adjustments in these patients. OBJECTIVES: This study investigated the effects of LI-NPPV on the clinical course of patients with CRF as compared with patients who were treated with conventional NPPV (C-NPPV) and determined how frequently NPPV was adjusted during therapy...
April 2016: Annals of Thoracic Medicine
Annelijn M Meeder, Dave H T Tjan, Arthur R H van Zanten
BACKGROUND: Noninvasive positive pressure ventilation (NPPV) for acute respiratory failure in the intensive care unit (ICU) is associated with a marked reduction in intubation rate, complications, hospital length of stay and mortality. Multiple studies have indicated that patients failing NPPV have worse outcomes compared with patients with successful NPPV treatment; however limited data is available on risks associated with NPPV failure resulting in (delayed) intubation and outcomes compared with initial intubation...
May 2016: Journal of Thoracic Disease
Tao Huang, Hua Wang, Jixiang Tan
OBJECTIVE: To investigate the influence of exhalation valve location as well as its type on carbon dioxide (CO2) rebreathing during noninvasive positive pressure ventilation (NPPV). METHODS: With a standardized NPPV experimental model system, the exhalation valve was respectively installed between the ventilator tube and mask (position II), or on the mask (position II). This study included four groups according to the position and type of exhalation valve, namely: single-arch exhalation valve was installed on the position I (A group), and position II (C group, the distal end of single-arch exhalation valve was blocked); plateau exhalation valve was installed on the position I (B group) and position II (D group, the distal end of plateau exhalation valve was blocked)...
October 2015: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Takayoshi Shimohata, Naotaka Aizawa, Hideaki Nakayama, Hiroshige Taniguchi, Yasuyoshi Ohshima, Hitoshi Okumura, Tetsuya Takahashi, Akio Yokoseki, Makoto Inoue, Masatoyo Nishizawa
BACKGROUND: Sudden death in multiple system atrophy (MSA) usually occurs during sleep and was therefore attributed to suffocation resulting from vocal cord abductor paralysis, a characteristic laryngeal finding of MSA. This led to the use of tracheostomy and noninvasive positive pressure ventilation (NPPV) for the prevention of sudden death. However, neither method has been able to prevent sudden death, and both have occasionally precipitated treatment-related complications, including central sleep apneas and exacerbation of floppy epiglottis...
September 2016: Parkinsonism & related Disorders
Shinya Oda, Kei Otaki, Nozomi Yashima, Misato Kurota, Sachiko Matsushita, Airi Kumasaka, Hutaba Kurihara, Kaneyuki Kawamae
PURPOSE: Noninvasive positive pressure ventilation (NPPV) using a helmet is expected to cause inspiratory trigger delay due to the large collapsible and compliant chamber. We compared the work of breathing (WOB) of NPPV using a helmet or a full face-mask with that of invasive ventilation by tracheal intubation. METHODS: We used a lung model capable of simulating spontaneous breathing (LUNGOO; Air Water Inc., Japan). LUNGOO was set at compliance (C) = 50 mL/cmH2O and resistance (R) = 5 cmH2O/L/s for normal lung simulation, C = 20 mL/cmH2O and R = 5 cmH2O/L/s for restrictive lung, and C = 50 mL/cmH2O and R = 20 cmH2O/L/s for obstructive lung...
August 2016: Journal of Anesthesia
Qin Tang, Guangmei Qin
OBJECTIVE: To determine the efficacy of long-term noninvasive positive pressure ventilation (NPPV) on stable chronic obstructive pulmonary disease (COPD). 
 METHODS: Information was collected from the database of China National Knowledge Infrastructure (CNKI), WanFang, WeiPu, PubMed, EMbase, CBM (from the begining to October 2014). Statistical analysis was performed with the Cochrane Collaboration's software RevMan 5.2.
 RESULTS: A total of 23 trials involving 1 200 patients were included...
March 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
David J Walker, Wolfram Windisch, Michael Dreher
We are grateful to Ulasli and Esquinas for their comments to our paper.. They argued that arterial blood gas analyses were not performed without oxygen prior to the 6-minute walk test with noninvasive ventilation (6MWT-NPPV). This point has already been discussed in our original work by indicating the limitations of our study. The reason for using oxygen prior to exercise testing was to guarantee comparable starting conditions.
August 2016: COPD
Raffaele Scala
Flexible bronchoscopy (FBO) and non-invasive positive pressure ventilation (NIPPV) are largely applied in respiratory and general intensive care units. FBO plays a crucial role for the diagnosis of lung infiltrates of unknown origin and for the treatment of airways obstruction due to bronchial mucous plugging and hemoptysis in critical patients. NIPPV is the first-choice ventilatory strategy for acute respiratory failure (ARF) of different causes as it could be used as prevention or as alternative to the conventional mechanical ventilation (CMV) via endotracheal intubation (ETI)...
September 2016: Panminerva Medica
Tino Prell, Thomas M Ringer, Kara Wullenkord, Philipp Garrison, Anne Gunkel, Beatrice Stubendorff, Otto W Witte, Julian Grosskreutz
BACKGROUND: Non-invasive positive-pressure ventilation (NPPV) is an established, effective, long-term treatment for patients with amyotrophic lateral sclerosis (ALS), but the correct indicators for the establishment of NPPV have not been defined. METHODS: In this retrospective study, records (spirometry, nocturnal polygraphy, nocturnal blood gases) of 131 patients with ALS were reviewed in order to evaluate the role of polygraphy for prediction of respiratory failure in ALS...
September 2016: Journal of Neurology, Neurosurgery, and Psychiatry
Yoshinobu Ichiki, Junji Kawasaki, Tetsuro Yoshida, Takayuki Hamatsu, Taketoshi Suehiro, Fumihiro Tanaka, Keizo Sugimachi
The utility of stent placements has been widely reported. We performed a thought-provoking stent placement for malignant tracheal stenosis recently. A 90-year-old woman who was admitted to our hospital because of a urinary tract infection was treated with a course of antibiotics, but she demonstrated a rapidly progressive course with dyspnea. Chest computed tomography showed severe tracheal stenosis due to an upper mediastinal mass. She was put on noninvasive positive pressure ventilation (NPPV) because of severe respiratory failure...
March 1, 2016: Journal of UOEH
M P Di Yorio, D I Pérez Sirkin, T H Delgadin, A Shimizu, K Tsutsui, G M Somoza, P G Vissio
The role of gonadotrophin-inhibitory hormone (GnIH) in the inhibition of the reproductive axis has been well-established in birds and mammals. However, its role in other vertebrates, such as the teleost fish, remains controversial. In this context, the present study aimed to evaluate whether GnIH modulates the release of gonadotrophins and growth hormone (GH) in the cichlid fish Cichlasoma dimerus. First, we partially sequenced the precursor polypeptide for GnIH and identified three putative GnIH peptides. Next, we analysed the expression of this precursor polypeptide via a polymerase chain reaction in the reproductive axis of both sexes...
May 2016: Journal of Neuroendocrinology
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