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Catheter infections: definition epidemiology

Maria N Gamaletsou, Thomas J Walsh, Nikolaos V Sipsas
Invasive fungal infections caused by drug-resistant organisms are an emerging threat to heavily immunosuppressed patients with hematological malignancies. Modern early antifungal treatment strategies, such as prophylaxis and empirical and preemptive therapy, result in long-term exposure to antifungal agents, which is a major driving force for the development of resistance. The extended use of central venous catheters, the nonlinear pharmacokinetics of certain antifungal agents, neutropenia, other forms of intense immunosuppression, and drug toxicities are other contributing factors...
March 1, 2018: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
L López-González, F J Candel, J M Viñuela-Prieto, J González-Del Castillo, A B García, I Pena, I Rodríguez-Avial
OBJECTIVE: The aim of this study is to know epidemiologic and clinical differences among those patients colonized or infected by carbapenemase-producing Enterobacteriaceae (CPE) and develop a predictive model to facilitate the clinical approach concerning to start antimicrobial therapy. METHODS: Observational retrospective cohort study was performed involving all patients with Urine carbapenemase-producing Enterobacteriaceae isolation (UCPEI) between November 2013 and July 2015...
December 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
Shin-Huei Kuo, Wei-Ru Lin, Jun-You Lin, Chung-Hao Huang, Ya-Ting Jao, Pei-Wen Yang, Jong-Rung Tsai, Wen-Hung Wang, Yen-Hsu Chen, Ching-Tzu Hung, Po-Liang Lu
BACKGROUND/PURPOSE: For high risk of central line-associated bloodstream infections (CLABSIs) in patients of intensive care units (ICUs) and scarcely epidemiology and therapeutic recommendations in Asia, we aimed to evaluate the annual change in epidemiology, antibiogram, and risk factors for 14-day mortality. METHODS: A retrospective study of ICUs patients with CLABSIs at a medical center in Taiwan (2010-2016), where central line care bundle implemented since 2014, by reviewing clinical data, pathogens, and the antibiogram...
September 6, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
V Vásquez, D Ampuero, B Padilla
Urinary tract infection (UTI) is one of the major nosocomial infections. In more than 80% of cases it is related to the use of urological devices, especially linked to the misuse of urinary catheters. Empirical treatment should be based on local epidemiology, severity criteria and risk of multiresistant bacteria. This review shows the most important aspects of nosocomial UTI, as well as the recommendations for correct treatment adjustment; both empirical and definitive, that is the great challenge to avoid multiresistance, as well as to avoid unnecessary treatments...
September 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
Narayan Prasad Parajuli, Subhash Prasad Acharya, Santosh Dahal, Jaya Prasad Singh, Shyam Kumar Mishra, Hari Prasad Kattel, Basista Prasad Rijal, Bharat Mani Pokhrel
BACKGROUND: Device-associated health care-acquired infections (DA-HAIs) in intensive care unit patients are a major cause of morbidity, mortality, and increased health care costs. METHODS: A prospective, structured clinicomicrobiological surveillance was carried out for 3 common DA-HAIs: ventilator-associated pneumonia (VAP), central line-associated bloodstream infection (CLABSI), and catheter-associated urinary tract infection (CAUTI) present in the patients of an intensive care unit of a teaching hospital in Nepal...
September 1, 2017: American Journal of Infection Control
Arne Simon, Rhoikos Furtwängler, Norbert Graf, Hans Jürgen Laws, Sebastian Voigt, Brar Piening, Christine Geffers, Philipp Agyeman, Roland A Ammann
Pediatric patients receiving conventional chemotherapy for malignant disease face an increased risk of bloodstream infection (BSI). Since BSI may represent an acute life-threatening event in patients with profound immunosuppression, and show further negative impact on quality of life and anticancer treatment, the prevention of BSI is of paramount importance to improve and guarantee patients' safety during intensive treatment. The great majority of all pediatric cancer patients (about 85%) have a long-term central venous access catheter in use (type Broviac or Port; CVAD)...
2016: GMS Hygiene and Infection Control
Therèse M Duane, Rajesh Ramanathan, Patricia Leavell, Catherine Mays, Janis Ober
BACKGROUND: The incidences of hospital-acquired conditions, such as catheter-associated urinary tract infections (CAUTIs) and central line-associated blood stream infections (CLABSIs) are being used to compare quality at institutions and determine reimbursements. These data come from the University HealthSystem Consortium (UHC) administrative database that relies almost exclusively on physician documentation as opposed to objective U.S. Centers for Disease Control and Prevention (CDC) guidelines...
February 2016: Surgical Infections
Marta Wałaszek
INTRODUCTION: The patients in the neurosurgical ward are exposed to many risk factors causing nosocomial infections. These factors are related to operations, invasive diagnosing and monitoring of the nervous system and mechanical support of vital functions. Therefore, the objective of the undertaken studies was to assess the prevalence and structure of the healthcare-associated infections (HAI) in patients hospitalized in the neurosurgical ward in the St. Lukas District Hospital in Tarnów...
2015: Przegla̧d Epidemiologiczny
Kuan-Yin Lin, Aristine Cheng, Yu-Ching Chang, Mei-Chuan Hung, Jann-Tay Wang, Wang-Huei Sheng, Po-Ren Hseuh, Yee-Chun Chen, Shan-Chwen Chang
BACKGROUND/PURPOSE: Patients admitted to intensive care units (ICUs) are at high risk for central line-associated bloodstream infections (CLABSIs). Bundle care has been documented to reduce CLABSI rates in Western countries, however, few reports were from Asian countries and the differences in the epidemiology or outcomes of critically-ill patients with CLABSIs after implementation of bundle care remain unknown. We aimed to evaluate the incidence, microbiological characteristics, and factors associated with mortality in critically-ill patients after implementation of bundle care...
June 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Rudy Tedja, Jean Wentink, John C O'Horo, Rodney Thompson, Priya Sampathkumar
OBJECTIVE: To delineate the epidemiology of catheter-associated urinary tract infections (CAUTIs) and to better understand the value of urine cultures for evaluation of fever in the intensive care unit (ICU) setting DESIGN: Two-year retrospective review (2012-2013) SETTING: A single tertiary center with 1,200 hospital beds and 158 adult ICU beds PATIENTS: ICU patients with a CAUTI event METHODS: The cohort was identified from a prospective infection prevention database...
November 2015: Infection Control and Hospital Epidemiology
Anupama Neelakanta, Sarit Sharma, Vishnu Priya Kesani, Madiha Salim, Amina Pervaiz, Nida Aftab, Tal Mann, Nader Tashtoush, Shigehiko Karino, Sorabh Dhar, Keith S Kaye
The impact of the 2013 NHSN CAUTI definition on CAUTI rates was analyzed. A total of 107 CAUTI episodes were identified; 60 according to NHSN 2013 definitions only and 47 according to the 2012 and 2013 definitions. Physician-diagnosed "other infections" were more common among patients who had CAUTI only according to NHSN 2013 definitions (P<.001).
March 2015: Infection Control and Hospital Epidemiology
Wilhelmina Strasheim, Martha M Kock, Veronica Ueckermann, Ebrahim Hoosien, Andries W Dreyer, Marthie M Ehlers
BACKGROUND: The burden of catheter-related infections (CRIs) in developing countries is severe. In South Africa, a standardised surveillance definition does not exist and the collection of catheter days is challenging. The aim of the study was to provide baseline data on the prevalence of CRIs and to describe the epidemiology of CRI events within a tertiary academic hospital. METHODS: Surveillance was laboratory-based and conducted for a six month period. A microbiologically confirmed CRBSI (MC-CRBSI) event was defined as the isolation of the same microorganism from the catheter and concomitant blood cultures (BCs), within 48 h of catheter removal, which were not related to an infection at another site...
January 8, 2015: BMC Infectious Diseases
Valerio Iacovelli, Gabriele Gaziev, Luca Topazio, Pierluigi Bove, Giuseppe Vespasiani, Enrico Finazzi Agrò
Nosocomial urinary tract infections are a common complication in healthcare systems worldwide. A review of the literature was performed in June 2014 using the Medical Literature Analysis and Retrieval System Online (MEDLINE) database, through either PubMed or Ovid as a search engine, to identify publications regarding nosocomial urinary tract infections (NUTIs) definition, epidemiology, etiology and treatment.According to current definitions, more than 30% of nosocomial infections are urinary tract infections (UTIs)...
October 2014: Urologia
K Poesen, H Pottel, J Colaert, C De Niel
OBJECTIVES: Guidelines for diagnosis of infective endocarditis are largely based upon epidemiological studies in referral hospitals. Referral bias, however, might impair the validity of guidelines in non-referral hospitals. Recent studies in non-referral care centres on infective endocarditis are sparse. We conducted a retrospective epidemiological study on infective endocarditis in a large non-referral hospital in a Belgian city (Kortrijk). METHODS: The medical record system was searched for all cases tagged with a putative diagnosis of infective endocarditis in the period 2003-2010...
June 2014: Acta Clinica Belgica
Cristiane Silveira Brito, Rosineide Marques Ribas, Daiane Silva Resende, Denise Von Dolinger de Brito, Vânia Olivetti Steffen Abdallah, Kátia Regina Netto dos Santos, Fernanda Sampaio Cavalcante, Pricilla Dias Moura de Matos, Paulo P Gontijo Filho
OBJECTIVE: To investigate the pathogenesis of bloodstream infection by Staphylococcus epidermidis, using the molecular epidemiology, in high-risk neonates. METHODS: We conducted a prospective study of a cohort of neonates with bloodstream infection using central venous catheters for more than 24h. "National Healthcare Safety Network" surveillance was conducted. Genotyping was performed by DNA fingerprinting and mecA genes and icaAD were detected by multiplex-PCR...
July 2014: Brazilian Journal of Infectious Diseases
Rudy Tedja, Steven M Gordon, Cynthia Fatica, Thomas G Fraser
OBJECTIVE: To review and describe device utilization and central line-associated bloodstream (CLABSI) events among patients in a non-intensive care unit (ICU) setting and to examine the morbidity and mortality associated with these events. DESIGN: One-year descriptive review. SETTING: A single tertiary center with a 1,200-bed hospital and 209 adult ICU beds. PATIENTS: Hospitalized patients identified as having a CLABSI event attributed to a non-ICU setting...
February 2014: Infection Control and Hospital Epidemiology
Ewa Helwich, Jadwiga Wójkowska-Mach, Maria Borszewska-Kornacka, Janusz Gadzinowski, Ewa Gulczyńska, Agnieszka Kordek, Dorota Pawlik, Jerzy Szczapa, Joanna Domańska, Jerzy Klamka, Piotr B Heczko
AIM OF STUDY: 1. prospective record of infections; 2. prevention of nosocomial infections by providing current data about infections, which are significant for making therapeutic decisions. MATERIAL AND METHODS: Recorded infections: early-onset sepsis (congenital), late-onset sepsis (acquired in hospital), necrotising enterocolitis (NEC), pneumonia. Infections were diagnosed and qualified on the basis of definitions of infections based on the National Nosocomial Infections Surveillance (NNIS) criteria, developed by CDC, USA, including modifications of German Neo-KISS programme...
July 2013: Medycyna Wieku Rozwojowego
Michael L Rinke, David G Bundy, Aaron M Milstone, Kristin Deuber, Allen R Chen, Elizabeth Colantuoni, Marlene R Miller
BACKGROUND: A study was conducted to investigate health care agency central line-associated bloodstream infection (CLABSI) definitions and prevention policies and pare them to the Joint Commission National Patient Safety Goal (NPSG.07.04.01), the Centers for Disease Control and Prevention (CDC) CLABSI prevention recommendations, and a best-practice central line care bundle for inpatients. METHODS: A telephone-based survey was conducted in 2011 of a convenience sample of home health care agencies associated with children's hematology/oncology centers...
August 2013: Joint Commission Journal on Quality and Patient Safety
Isaac See, Martha Iwamoto, Kathy Allen-Bridson, Teresa Horan, Shelley S Magill, Nicola D Thompson
OBJECTIVE: To assess challenges to implementation of a new National Healthcare Safety Network (NHSN) surveillance definition, mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI). DESIGN: Multicenter field test. SETTING: Selected locations of acute care hospitals participating in NHSN central line-associated bloodstream infection (CLABSI) surveillance. METHODS: Hospital staff augmented their CLABSI surveillance for 2 months to incorporate MBI-LCBI: a primary bloodstream infection due to a selected group of organisms in patients with either neutropenia or an allogeneic hematopoietic stem cell transplant with gastrointestinal graft-versus-host disease or diarrhea...
August 2013: Infection Control and Hospital Epidemiology
Jadwiga Wójkowska-Mach, Magda Baran, Rafał Drwiła, Mirosław Ziętkiewicz, Ewelina Foryciarz, Edyta Synowiec, Dorota Romaniszyn, Piotr B Heczko
BACKGROUND: The aim of this study was to analyse the epidemiology and aetiology of laboratoryconfirmed bloodstream infections (LC-BSI) and central line-associated bloodstream infections (CLABSI) after pulmonary and coronary surgery, in postoperative intensive care units in 2009. METHODS: Sources of infections were identified by the hospital Infection Control Team in cooperation with ITU personnel using the CDC definitions. RESULTS: A total of 37 LC-BSI and 21 CLA-BSI cases in 3...
January 2012: Anaesthesiology Intensive Therapy
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