keyword
MENU ▼
Read by QxMD icon Read
search

Brain cooling

keyword
https://www.readbyqxmd.com/read/28049450/yawning-reduces-facial-temperature-in-the-high-yawning-subline-of-sprague-dawley-rats
#1
Jose R Eguibar, Carlos A Uribe, Carmen Cortes, Amando Bautista, Andrew C Gallup
BACKGROUND: Yawning is a stereotyped behavior that enhances blood flow to the skull, and the resulting counterflow has been hypothesized as a mechanism for brain cooling. Studies have shown that yawns are strongly associated with physiological and pathological conditions that increase brain temperature, and that they are followed by equivalent decreases in brain temperature. However, measured reductions in cranial or facial temperatures following yawning have yet to be reported, to our knowledge...
January 3, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28038481/selective-brain-cooling-after-traumatic-brain-injury-effects-of-three-different-cooling-methods-case-report
#2
Thomas Westermaier, Robert Nickl, Stefan Koehler, Patrick Fricke, Christian Stetter, Stefan Mark Rueckriegel, Ralf-Ingo Ernestus
Background In experimental models of neuronal damage, therapeutic hypothermia proved to be a powerful neuroprotective method. In clinical studies of traumatic brain injury (TBI), this very distinct effect was not reproducible. Several meta-analyses draw different conclusions about whether therapeutic hypothermia can improve outcome after TBI. Adverse side effects of systemic hypothermia, such as severe pneumonia, have been held responsible by some authors to counteract the neuroprotective effect. Selective brain cooling (SBC) attempts to take advantage of the protective effects of therapeutic hypothermia without the adverse side effects of systemic hypothermia...
December 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28010747/using-on-line-solid-phase-extraction-for-in%C3%A2-vivo-speciation-of-diffusible-ferrous-and-ferric-iron-in-living-rat-brain-extracellular-fluid
#3
Cheng-Kuan Su, Yi-Ting Chen, Yuh-Chang Sun
Exploration of brain extracellular non-protein-bound/diffusible iron species remains a critically important issue in investigations of free radical biology and neurodegenerative diseases. In this study, a facile sample pretreatment scheme, involving poly(vinyl chloride)-metal ion interactions as a selective extraction procedure, was optimized in conjunction with microdialysis (MD) sampling and inductively coupled plasma mass spectrometry (ICP-MS) in cool-plasma mode for in vivo online monitoring of rat brain extracellular Fe(II) and Fe(III) species...
February 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28008425/quantitative-pet-mri-evaluation-and-application-in-dementia
#4
Yongxia Zhou
A recently introduced integrated scanner combining simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) acquisition presents a unique set of opportunities for neuroimaging research and dementia in particular [1]. Among these, the intrinsic co-registration of the images has the potential to reduce errors in multi-modality image registration, which could lead to better quantification of longitudinal volumetric changes in neuroanatomical features that are important for assessing disease progression...
June 2016: Jacobs J Med Diagn Med Imaging
https://www.readbyqxmd.com/read/27997033/brain-mechanisms-of-abnormal-temperature-perception-in-cold-allodynia-induced-by-ciguatoxin
#5
Anneka Eisenblätter, Richard Lewis, Arnd Dörfler, Clemens Forster, Katharina Zimmermann
OBJECTIVE: Cold allodynia occurs as a major symptom of neuropathic pain states. It remains poorly treated with current analgesics. Ciguatoxins (CTXs), ichthyosarcotoxins that cause ciguatera, produce a large peripheral sensitization to dynamic cold stimuli in Aδ-fibers by activating sodium channels without producing heat or mechanical allodynia. We used CTXs as surrogate model of cold allodynia to dissect the framework of cold allodynia activated central pain pathways. METHODS: Reversible cold allodynia was induced in healthy male volunteers by shallow intracutaneous injection of low nM concentrations of CTX into the dorsal skin of the forefoot...
December 20, 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27988879/therapeutic-hypothermia-for-neonatal-hypoxic-ischemic-encephalopathy-is-associated-with-short-term-reduction-of-seizures-after-discharge-from-the-neonatal-intensive-care-unit
#6
Suman Ghosh, Lily Tran, Jonathan J Shuster, Mary L Zupanc
INTRODUCTION: Therapeutic hypothermia for the treatment of moderate to severe neonatal hypoxic ischemic encephalopathy has been shown to reduce death and disability, but the effects on seizures after discharge from the Neonatal ICU are not known. METHODS: A retrospective cohort study was conducted involving 56 neonates admitted to the Neonatal ICU at Children's Hospital of Orange County, CA from January 1, 2007 to September 1, 2013 with hypoxic ischemic encephalopathy who met criteria for selective brain cooling...
December 17, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27978510/optimizing-cerebral-autoregulation-may-decrease-neonatal-regional-hypoxic-ischemic-brain-injury
#7
Jennifer K Lee, Andrea Poretti, Jamie Perin, Thierry A G M Huisman, Charlamaine Parkinson, Raul Chavez-Valdez, Matthew O'Connor, Michael Reyes, Jillian Armstrong, Jacky M Jennings, Maureen M Gilmore, Raymond C Koehler, Frances J Northington, Aylin Tekes
BACKGROUND: Therapeutic hypothermia provides incomplete neuroprotection for neonatal hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that support autoregulation are associated with decreased brain injury and whether these relationships are affected by birth asphyxia or vary by anatomic region. METHODS: Neonates cooled for HIE received near-infrared spectroscopy autoregulation monitoring to identify the mean arterial blood pressure with optimized autoregulatory function (MAPOPT)...
December 16, 2016: Developmental Neuroscience
https://www.readbyqxmd.com/read/27959970/magnetic-resonance-thermometry-guided-stereotactic-laser-ablation-of-cavernous-malformations-in-drug-resistant-epilepsy-imaging-and-clinical-results
#8
D Jay McCracken, Jon T Willie, Brad Fernald, Amit M Saindane, Daniel L Drane, Daniel L Barrow, Robert E Gross
BACKGROUND: Surgery is indicated for cerebral cavernous malformations (CCM) that cause medically refractory epilepsy. Real-time magnetic resonance thermography (MRT)-guided stereotactic laser ablation (SLA) is a minimally invasive approach to treating focal brain lesions. SLA of CCM has not previously been described. OBJECTIVE: To describe MRT-guided SLA, a novel approach to treating CCM-related epilepsy, with respect to feasibility, safety, imaging, and seizure control in 5 consecutive patients...
March 2016: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/27941370/meta-analysis-of-therapeutic-hypothermia-for-traumatic-brain-injury-in-adult-and-pediatric-patients
#9
Ellie M Crompton, Irina Lubomirova, Ioana Cotlarciuc, Thang S Han, Sapna D Sharma, Pankaj Sharma
OBJECTIVE: Therapeutic hypothermia has been used to attenuate the effects of traumatic brain injuries. However, the required degree of hypothermia, length of its use, and its timing are uncertain. We undertook a comprehensive meta-analysis to quantify benefits of hypothermia therapy for traumatic brain injuries in adults and children by analyzing mortality rates, neurologic outcomes, and adverse effects. DATA SOURCES: Electronic databases PubMed, Google Scholar, Web of Science, Cochrane Central Register of Controlled Trials, and ClinicalTrials...
December 9, 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27933367/antipsychotic-inductors-of-brain-hypothermia-and-torpor-like-states-perspectives-of-application
#10
REVIEW
Yury S Tarahovsky, Irina S Fadeeva, Natalia P Komelina, Maxim O Khrenov, Nadezhda M Zakharova
Hypothermia and hypometabolism (hypometabothermia) normally observed during natural hibernation and torpor, allow animals to protect their body and brain against the damaging effects of adverse environment. A similar state of hypothermia can be achieved under artificial conditions through physical cooling or pharmacological effects directed at suppression of metabolism and the processes of thermoregulation. In these conditions called torpor-like states, the mammalian ability to recover from stroke, heart attack, and traumatic injuries greatly increases...
January 2017: Psychopharmacology
https://www.readbyqxmd.com/read/27895985/multi-channel-multi-distance-broadband-near-infrared-spectroscopy-system-to-measure-the-spatial-response-of-cellular-oxygen-metabolism-and-tissue-oxygenation
#11
Phong Phan, David Highton, Jonathan Lai, Martin Smith, Clare Elwell, Ilias Tachtsidis
We present a multi-channel, multi-distance broadband near-infrared spectroscopy (NIRS) system with the capability of measuring changes in haemoglobin concentrations (Δ[HbO2], Δ[HHb]), oxidation state of cytochrome-c-oxidase (Δ[oxCCO]) and tissue oxygen saturation (TOI) in the adult human brain. The main components of the instrument are two customized spectrographs and two light sources. Each spectrograph is lens-based to improve light throughput, has a grating enhanced to optimise reflection in the near-infrared (NIR) spectral region and uses a front illuminated cooled CCD camera (-70° C) with a square chip dimension of 12...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27888923/determination-of-time-of-death-in-forensic-science-via-a-3-d-whole-body-heat-transfer-model
#12
Catherine Bartgis, Alexander M LeBrun, Ronghui Ma, Liang Zhu
This study is focused on developing a whole body heat transfer model to accurately simulate temperature decay in a body postmortem. The initial steady state temperature field is simulated first and the calculated weighted average body temperature is used to determine the overall heat transfer coefficient at the skin surface, based on thermal equilibrium before death. The transient temperature field postmortem is then simulated using the same boundary condition and the temperature decay curves at several body locations are generated for a time frame of 24h...
December 2016: Journal of Thermal Biology
https://www.readbyqxmd.com/read/27857953/spinal-cord-thermosensitivity-an-afferent-phenomenon
#13
REVIEW
James A Brock, Robin M McAllen
We review the evidence for thermoregulatory temperature sensors in the mammalian spinal cord and reach the following conclusions. 1) Spinal cord temperature contributes physiologically to temperature regulation. 2) Parallel anterolateral ascending pathways transmit signals from spinal cooling and spinal warming: they overlap with the respective axon pathways of the dorsal horn neurons that are driven by peripheral cold- and warm-sensitive afferents. 3) We hypothesize that these 'cold' and 'warm' ascending pathways transmit all extracranial thermosensory information to the brain...
April 2016: Temperature: Multidisciplinary Biomedical Journal
https://www.readbyqxmd.com/read/27857952/regional-brain-responses-in-humans-during-body-heating-and-cooling
#14
REVIEW
Michael J Farrell
Functional brain imaging of responses to thermal challenge in humans provides a viable method to implicate widespread neuroanatomical regions in the processes of thermoregulation. Thus far, functional neuroimaging techniques have been used infrequently in humans to investigate thermoregulation, although preliminary outcomes have been informative and certainly encourage further forays into this field of enquiry. At this juncture, sustained regional brain activations in response to prolonged changes in body temperature are yet to be definitively characterized, but it would appear that thermoregulatory regions are widely distributed throughout the hemispheres of the human brain...
April 2016: Temperature: Multidisciplinary Biomedical Journal
https://www.readbyqxmd.com/read/27830952/return-to-work-following-acquired-brain-injury-the-views-of-patients-and-employers
#15
Birgit H P M Donker-Cools, Maria J E Schouten, Haije Wind, Monique H W Frings-Dresen
PURPOSE: To investigate which factors are experienced as facilitators of or barriers to return to work (RTW), or as solutions to RTW-problems, by patients with acquired brain injury (ABI) and by employers. DESIGN: Qualitative study. METHOD: Ten patients with ABI and seven employers participated in semi-structured interviews. Patients and employers were unrelated. Transcripts were open coded. Factors perceived to be facilitators, barriers, or solutions to RTW-problems were grouped on a thematic basis...
November 10, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27823842/cerebral-sinovenous-thrombosis-in-the-asphyxiated-cooled-infants-a-prospective-observational-study
#16
Maurizio Radicioni, Vittorio Bini, Pietro Chiarini, Ambra Fantauzzi, Francesca Leone, Raffaella Scattoni, Pier Giorgio Camerini
BACKGROUND: Cerebral sinovenous thrombosis is unusual in the asphyxiated cooled infants, but reliable data regarding the incidence of this comorbidity are lacking. We assessed the incidence of sinovenous thrombosis in a population of asphyxiated cooled infants by performing routine brain magnetic resonance venography. METHODS: All asphyxiated infants who underwent therapeutic cooling at our institution completed brain magnetic resonance venography after rewarming...
January 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/27808277/the-influence-of-warm-ischemia-elimination-on-kidney-injury-during-transplantation-clinical-and-molecular-study
#17
Dorota Kamińska, Katarzyna Kościelska-Kasprzak, Paweł Chudoba, Agnieszka Hałoń, Oktawia Mazanowska, Agnieszka Gomółkiewicz, Piotr Dzięgiel, Dominika Drulis-Fajdasz, Marta Myszka, Agnieszka Lepiesza, Wojciech Polak, Maria Boratyńska, Marian Klinger
Kidney surface cooling was used during implantation to assess the effect of warm ischemia elimination on allograft function, histological changes and immune-related gene expression. 23 recipients were randomly assigned to a group operated on with kidney surface cooling during implantation (ice bag technique, IBT group), and the other 23 recipients receiving the contralateral kidney from the same donor were operated on with a standard technique. Three consecutive kidney core biopsies were obtained during the transplantation procedure: after organ recovery, after cold ischemia and after reperfusion...
November 3, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27805583/repetitive-transcranial-magnetic-stimulation-to-the-unilateral-hemisphere-of-rat-brain
#18
Jaewon Beom, Jung Chan Lee, Jin Chul Paeng, Tai Ryoon Han, Moon Suk Bang, Byung-Mo Oh
Previous rodent models of repetitive transcranial magnetic stimulation (rTMS) adopted whole-brain stimulation instead of unilateral hemispheric rTMS, which is unlike the protocols used for human subjects. We report a successful application of rTMS to the unilateral hemisphere of rat brain. The rTMS was delivered with a low-frequency (1 Hz), high-frequency (20 Hz), or sham stimulation protocol to one side of the brain by using a small 25-mm figure-8 coil. We placed the center of the coil 1 cm lateral to the vertex on the biauricular line and angulated the coil 45° to the ground to minimize a potential direct effect of rTMS on the contralateral cortex...
October 22, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27799012/selective-brain-hypothermia-mitigates-brain-damage-and-improves-neurological-outcome-after-post-traumatic-decompressive-craniectomy-in-mice
#19
Jacek Szczygielski, Andreas Müller, Angelika E Mautes, Christoph Sippl, Cosmin Glameanu, Karsten Schwerdtfeger, Wolf-Ingo Steudel, Joachim Oertel
Hypothermia and decompressive craniectomy (DC) have been considered as treatment for traumatic brain injury. The present study investigates whether selective brain hypothermia added to craniectomy could improve neurological outcome after brain trauma. Male CD-1 mice were assigned into the following groups: sham; DC; closed head injury (CHI); CHI followed by craniectomy (CHI+DC); and CHI+DC followed by focal hypothermia (CHI+DC+H). At 24 h post-trauma, animals were subjected to Neurological Severity Score (NSS) test and Beam Balance Score test...
January 3, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27784293/simultaneous-acoustic-stimulation-of-human-primary-and-secondary-somatosensory-cortices-using-transcranial-focused-ultrasound
#20
Wonhye Lee, Yong An Chung, Yujin Jung, In-Uk Song, Seung-Schik Yoo
BACKGROUND: Transcranial focused ultrasound (FUS) is gaining momentum as a novel non-invasive brain stimulation method, with promising potential for superior spatial resolution and depth penetration compared to transcranial magnetic stimulation or transcranial direct current stimulation. We examined the presence of tactile sensations elicited by FUS stimulation of two separate brain regions in humans-the primary (SI) and secondary (SII) somatosensory areas of the hand, as guided by individual-specific functional magnetic resonance imaging data...
October 26, 2016: BMC Neuroscience
keyword
keyword
32554
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"