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JOURNAL ARTICLE
Catherine Larson-Nath, Linder Wendt, Riad Rahhal
OBJECTIVES: Patients with intestinal failure require central venous access which puts them at risk for central line-associated bloodstream infections (CLABSI). Maintaining vascular patency is critical for this population to receive nutrition support. When CLABSIs occur line salvage can help maintain vascular access. The aim of this study is to assess factors associated with safe and successful central venous catheter salvage. METHODS: Retrospective cohort study of patients with intestinal failure at two tertiary care institutions between 2012 and 2020...
March 7, 2024: Journal of Pediatric Gastroenterology and Nutrition
#22
REVIEW
J K Teus, L Mithen, H Green, A Hutton, R Fernandez
BACKGROUND: The COVID-19 pandemic has posed an unprecedented challenge to healthcare systems globally. Personal protective equipment has played a fundamental role in protecting healthcare workers and patients, but its effectiveness in reducing hospital-acquired infections (HAIs) during the pandemic remains a subject of debate. AIM: To conduct a synthesis and meta-analysis of the best available evidence of the prevalence of HAIs using a before/after approach. METHODS: A three-step search strategy was undertaken to locate published and unpublished studies...
February 27, 2024: Journal of Hospital Infection
#23
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Healthcare-associated infections (HAIs) are a significant healthcare burden in Canada. National surveillance of HAIs at sentinel acute care hospitals is conducted by the Canadian Nosocomial Infection Surveillance Program. This article describes device and surgical procedure-related HAI epidemiology in Canada from 2017 to 2021. METHODS: Data were collected from over 60 Canadian sentinel acute care hospitals between January 1, 2017, and December 31, 2021, for central line-associated bloodstream infections (CLABSIs), hip and knee surgical site infections (SSIs), cerebrospinal fluid shunt SSIs and paediatric cardiac SSIs...
May 1, 2023: Canada Communicable Disease Report
#24
REVIEW
Nasim Lotfinejad, Jean-Marie Januel, Sarah Tschudin-Sutter, Peter W Schreiber, Bruno Grandbastien, Lauro Damonti, Elia Lo Priore, Alexandra Scherrer, Stephan Harbarth, Gaud Catho, Niccolò Buetti
INTRODUCTION: Intravascular catheters are crucial devices in medical practice that increase the risk of healthcare-associated infections (HAIs), and related health-economic adverse outcomes. This scoping review aims to provide a comprehensive overview of published automated algorithms for surveillance of catheter-related bloodstream infections (CRBSI) and central line-associated bloodstream infections (CLABSI). METHODS: We performed a scoping review based on a systematic search of the literature in PubMed and EMBASE from 1 January 2000 to 31 December 2021...
February 28, 2024: Antimicrobial Resistance and Infection Control
#25
JOURNAL ARTICLE
Danielle J Durant, Nancy Fallwell, Lesley Martinez, Claudia Guerrazzi-Young
BACKGROUND: Central line-associated bloodstream infection (CLABSI) causes significant harm in neonatal intensive care unit (NICU) patients. However, data regarding risk factors and prevention strategies for CLABSI in NICU patients is limited. OBJECTIVE: To examine risk factors for CLABSI in a NICU population, with particular interest in central line type and site placement. DESIGN: Retrospective case-control study. SETTING: NICU (Level IV, 67 bed) at a pediatric hospital in South Texas...
2024: Antimicrob Steward Healthc Epidemiol
#26
JOURNAL ARTICLE
Alfredo J Mena Lora, Brenna Lindsey, Stephanie Echeverria, Mirza Ali, Candice Krill, Eden Takhsh, Susan C Bleasdale
Overuse of peripherally inserted central catheters (PICCs) can lead to idle central line (CL) days and increased risk for CL-associated bloodstream infections (CLABSIs). We established a midline prioritization initiative at a safety-net community hospital. This initiative led to possible CLABSI avoidance and a decline in PICC use.
2024: Antimicrob Steward Healthc Epidemiol
#27
JOURNAL ARTICLE
Frank A Drews, Richard A Martinello, Joan N Hebden, Keith H St John, David A Pegues
OBJECTIVE: Evidence-based central-line-associated bloodstream infection (CLABSI) prevention guidelines recommend the use of an antiseptic scrub to disinfect needleless connectors before device access. Guideline noncompliance may render disinfection ineffective. The goal of this study was to observe needleless-connector disinfection practices and to identify perceived facilitators and barriers to best practices of needleless-connector access. METHODS: A human factors mixed-methods study involving nursing focus groups of perceived barriers and facilitators and clinical observations of compliance with instructions and protocols for use of 3...
February 23, 2024: Infection Control and Hospital Epidemiology
#28
REVIEW
Erica Almeida Carvalho Peixoto, Vanessa de Brito Poveda, Juliana Rizzo Gnatta, Ramon Antonio Oliveira
BACKGROUND: Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI. METHODS: Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions...
February 10, 2024: American Journal of Infection Control
#29
JOURNAL ARTICLE
Asad Latif, Wajid Ali, Sohail Haleem, Faisal Mahmood, Tahir Munir, Nazleen Virani, Hamza Khan, Maqbool Qadir, Rozina Roshan, Khairunnissa Hooda, Nadeem Mustafa Khan, Afia Zafar, Peter Pronovost
BACKGROUND: Central line-associated bloodstream infections (CLABSIs) pose a significant risk to critically ill patients, particularly in intensive care units (ICU) and are a significant cause of hospital-acquired infections. We investigated whether implementation of a multifaceted intervention was associated with reduced incidence of CLABSIs. METHODOLOGY: This was a prospective cohort study over 9 years. We implemented a bundled intervention approach to prevent CLABSIs, consisting of a comprehensive unit-based safety program (CUSP)...
February 7, 2024: American Journal of Infection Control
#30
JOURNAL ARTICLE
Vaibhav R Suryawanshi, Atmaram Pawar, Bharat Purandare, Niveda Vijayvargiya, Sandesh Sancheti, Susan Philip, Prasad Nagare
BACKGROUND: There is a scarcity of studies evaluating the microbial profile, antimicrobial susceptibility, and prevalence of MDR/XDR pathogens causing medical device-associated infections (MDAIs). The present study was sought in this regard. MATERIALS AND METHODS: An ambispective-observational, site-specific, surveillance-based study was performed for a period of 2 years in the intensive care unit (ICU) and high dependency unit (HDU) (medicine/surgery) of a Tertiary-care University Hospital...
February 2024: Indian Journal of Critical Care Medicine
#31
JOURNAL ARTICLE
Ceder H van den Bosch, Florine N J Frakking, Yvette G T Loeffen, Harm van Tinteren, Alida F W van der Steeg, Marc H W A Wijnen, Marianne D van de Wetering, Jan-Tom van der Bruggen
BACKGROUND: The aim of this study was to investigate the applicability of the central line-associated bloodstream infection (CLABSI) criteria of the Centers for Disease Control and Prevention in pediatric oncology patients. METHODS: Bacteremia episodes from 2020 to 2022 from a prospective cohort of pediatric oncology patients with a central venous catheter were included. Episodes were classified by three medical experts following the CLABSI criteria as either a CLABSI or non-CLABSI (i...
January 31, 2024: European Journal of Haematology
#32
JOURNAL ARTICLE
Integration of Riboflavin-Modified Carbon Fiber Mesh Electrode Systems in a 3D-Printed Catheter Hub.
Charnete Casimero, Robert B Smith, James Davis
BACKGROUND: Catheter line infection is a common complication within clinical environments, and there is a pressing need for technological options to aid in reducing the possibility of sepsis. The early identification of contamination could be pivotal in reducing cases and improving outcomes. METHOD: A sensing rationale based on a riboflavin-modified electrode system integrated within a modified 3D-printed catheter needle-free connector is proposed, which can monitor changes in pH brought about by bacterial contamination...
December 30, 2023: Micromachines
#33
JOURNAL ARTICLE
Silvia Boni, Marina Sartini, Filippo Del Puente, Giulia Adriano, Elisabetta Blasi Vacca, Nicoletta Bobbio, Alessio Carbone, Marcello Feasi, Viviana Grasso, Marco Lattuada, Mauro Nelli, Martino Oliva, Andrea Parisini, Roberta Prinapori, Maria Carmela Santarsiero, Stefania Tigano, Maria Luisa Cristina, Emanuele Pontali
In several settings, the COVID-19 pandemic determined a negative impact on the occurrence of healthcare-associated infection, particularly for on central lines associated bloodstream infections (CLABSI). In our setting, we observed a significant increase in CLABSI in our intensive care unit (ICU) during 2020 and 2021 vs. 2018 to 2019. A refresher training activity on central venous catheter (CVC) management bundles was carried out in September-October 2021 for the ICU health staff. We assessed the impact of bundle implementation by means of standardized indicators, such as the Device Utilization Ratio (DUR), in this case, the Central Line Utilization Ratio, the Standardized Utilization Ratio (SUR), and the device Standardized Infection Ratio (dSIR)...
January 11, 2024: Journal of Clinical Medicine
#34
REVIEW
Tina Perme
Central lines are essential devices in NICUs, used primarily in preterm neonates and critically ill term neonates. They are typically divided into non-tunnelled, tunnelled and totally implanted. In light of the increasing use of central lines in the NICU setting, monitoring of the risk factors associated with complications has to be an important part of neonatal care quality management. Presented here is a case of a preterm neonate with cardiac tamponade caused by UVC tip migration. Among complications of central lines are CLABSI, with an incidence of 3 to 21 per 1000 catheter days, and portal vein thrombosis, which is common but probably under-recognised, whereas other mechanical complications such as pericardial and pleural effusions are rare, with an incidence of less than 1%...
December 25, 2023: Children
#35
JOURNAL ARTICLE
Hao Chen, Takamasa Yamane, Terunobu Haruyama, Masashi Ishihara, Hiroki Kazahari, Takahiko Sakamoto, Shigeru Tanzawa, Takeshi Honda, Yasuko Ichikawa, Kiyotaka Watanabe, Nobuhiko Seki
BACKGROUND: Central venous catheters (CVCs) are sometimes superior to peripheral vascular access for chemotherapy. Central line-associated bloodstream infections (CLABSIs) are an important complication of CVCs in chemotherapy. METHODS: A retrospective, observational study was conducted to investigate patients with implanted venous access ports (PORTs) from July 2010 to June 2021 in a teaching hospital. General conditions of the PORTs, backgrounds, and characteristics of patients were compared between CLABSI cases and uninfected cases to identify predictors of CLABSI...
December 31, 2023: Translational Cancer Research
#36
JOURNAL ARTICLE
Neeta Gade, Ranga Burri, Akkilagunta Sujiv, Meena Mishra, B E Pradeep, Harish Debaje, Tejswini Sable, Amandeep Kaur
INTRODUCTION: Device-associated healthcare infections are among the prevailing threats to patient safety worldwide. They constitute the third most common adverse event during healthcare delivery, resulting in heightened morbidity, mortality, and healthcare costs. Patients in intensive care units (ICUs) are at increased risk for device-associated healthcare infections. Focused active surveillance is a crucial measure for assessing the prevalence of healthcare-associated infections and controlling the transmission of pathogens, ultimately contributing to the establishment of quality outcome indicators...
December 2023: Curēus
#37
JOURNAL ARTICLE
Essa AlSaleh, Balajis Naik, Ali M AlSaleh
Introduction Patients admitted to intensive care units (ICU), especially those with devices used to support their condition, are at a higher risk of getting healthcare-associated infections (HAIs). The aim of the present study was to analyze the surveillance data and assess the device-associated infection (DAI) rates such as central line-associated blood-stream infection (CLABSI), catheter-associated urinary tract infection (CAUTI), ventilator-associated pneumonia (VAP) and ventilator-associated event (VAE) in ICUs of the Ministry of Health (MoH) hospitals in Al-Ahsa region...
December 2023: Curēus
#38
JOURNAL ARTICLE
Victor D Rosenthal, Ruijie Yin, Patricio Nercelles, Sara E Rivera-Molina, Somani Jyoti, Reshma Dongol, Daisy Aguilar-De-Moros, Nellie Tumu, Johana Alarcon-Rua, Juan P Stagnaro, Safaa Alkhawaja, Luisa F Jimenez-Alvarez, Yuliana A Cano-Medina, Sandra L Valderrama-Beltran, Claudia M Henao-Rodas, Maria A Zuniga-Chavarria, Amani El-Kholy, Hala Mounir Agha, Suneeta Sahu, Siksha O Anusandhan, Mahuya Bhattacharyya, Mohit Kharbanda, Aruna Poojary, Pravin K Nair, Sheila N Myatra, Rajesh Chawla, Kavita Sandhu, Yatin Mehta, Prasad Rajhans, Farid Zand, Mohammad Abdellatif-Daboor, Chian-Wern Tai, Chin S Gan, Mohd-Basri Mat Nor, Guadalupe Aguirre-Avalos, Blanca E Hernandez-Chena, Alejandro Sassoe-Gonzalez, Isabel Villegas-Mota, Mary C Aleman-Bocanegra, Ider Bat-Erdene, Nilton Y Carreazo, Alex Castaneda-Sabogal, Jarosław Janc, Vladislav Belskiy, Sona Hlinkova, Dincer Yildizdas, Merve Havan, Alper Koker, Hulya Sungurtekin, Ener C Dinleyici, Ertugrul Guclu, Lili Tao, Ziad A Memish, Zhilin Jin
BACKGROUND: Reporting on the International Nosocomial Infection Control Consortium study results from 2015 to 2020, conducted in 630 intensive care units across 123 cities in 45 countries spanning Africa, Asia, Eastern Europe, Latin America, and the Middle East. METHODS: Prospective intensive care unit patient data collected via International Nosocomial Infection Control Consortium Surveillance Online System. Centers for Disease Control and Prevention/National Health Care Safety Network definitions applied for device-associated health care-associated infections (DA-HAI)...
January 6, 2024: American Journal of Infection Control
#39
JOURNAL ARTICLE
Madhuri M Sopirala, Carolee D Estelle, La'Titia Houston
Centers for Medicare and Medicaid Services imparts financial penalties for central line-associated bloodstream infections (CLABSIs) and other healthcare-acquired infections. Data for this purpose is obtained from the Centers for Disease Control and Prevention (CDC)'s National Health Safety Network. We present examples of misclassification of bloodstream infections into CLABSI by the CDC's definition and present the financial implications of such misclassification and potential long-term implications.
March 1, 2024: Critical Care Medicine
#40
JOURNAL ARTICLE
Arshan Dehbozorgi, Badr Jandali, Robert Turner, Aaron Rohr, Brandon Custer, Kate Young, Carissa Walter, Lauren Clark, Yanming Li, Deepika Polineni, Joel Mermis
BACKGROUND: Peripherally inserted central catheters (PICCs) are the most common route of intravenous (I.V.) access for treatment of cystic fibrosis (CF) pulmonary exacerbations, but repeated PICC placement can result in upper extremity peripheral venous stenosis. Once peripheral stenosis develops, a non-cuffed tunneled central venous catheter (NcTCVC) is an alternative route for IV access. While these are regularly used at some CF centers, the safety and complication rate compared to PICCs in adults with CF has not been reported...
November 30, 2023: Respiratory medicine and research
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