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https://www.readbyqxmd.com/read/28212280/biofilm-formation-and-immunomodulatory-activity-of-proteus-mirabilis-clinically-isolated-strains
#1
Alessandra Fusco, Lorena Coretti, Vittoria Savio, Elisabetta Buommino, Francesca Lembo, Giovanna Donnarumma
Urinary tract infections (UTIs) and catheter-associated UTIs (CAUTIs) are the principal hospital-acquired infections. Proteus mirabilis is characterized by several virulence factors able to promote adhesion and biofilm formation and ameliorate the colonization of urinary tract and the formation of crystalline biofilms on the abiotic surface of the urinary catheters. Since, to date, the role of P. mirabilis in the etiopathogenesis of different types of urinary tract infections is not well established, in this study we sought to characterize two different clinically isolated strains of P...
February 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28212164/effectiveness-of-a-nurse-led-initiative-peer-to-peer-teaching-on-organizational-cauti-rates-and-related-costs
#2
Barbara Pashnik, Angela Creta, Lynette Alberti
A nurse-led initiative of peer-to-peer teaching positively impacted organizational incidence of catheter-associated urinary tract infections (CAUTIs). The initiative included validating the competency of the nursing staff, highlighting the importance of CAUTI prevention, identifying CAUTI costs, quantifying the value of nursing care, and supporting nurses as teachers. The project demonstrated that peer-to-peer teaching and competency validation can be effective methods to engage nurses in quality improvement...
February 16, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28152941/transforming-a-unit-s-culture-to-improve-clinical-outcomes
#3
Theresa Woodrum, Michael Romano
: 243 Background: Leadership identified an unhealthy work environment existed in our Oncology Hematology Special Care Unit (OHSCU). This was evidenced by increased turnover, low National Database of Nursing Quality Indicators (NDNQI), and nurse sensitive quality indicator scores. In the fall of 2014 changes were made to the unit with a goal of creating within the unit a culture of clinical excellence, engagement, professionalism, accountability, and improve staff satisfaction. METHODS: Leadership met to define the future state of the unit and develop a vision statement...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150261/-using-an-indicator-based-reminder-of-catheter-removal-to-effectively-decrease-catheter-associated-urinary-tract-infections-in-general-medical-patients
#4
Pey-Tsung Wang, Hsiang-Yu Lin, Yi-Tsun Lin, Wen-Huey Shin, Li-Yin Chien, Shirling Lin
BACKGROUND: Urinary tract infections are a common iatrogenic infection in healthcare institutions. Catheter-associated urinary tract infections (CAUTIs) may result in sepsis, prolonged hospitalization, additional hospital costs, and mortality. PURPOSE: The study examined the efficacy of an indicator-based reminder of catheter removal in decreasing CAUTIs among patients in the general medical ward. METHODS: A two-group, quasi-experimental design was used...
February 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28145178/preventing-cautis
#5
Rebecca Keown
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The CPD article discussed the symptoms of catheter-associated urinary tract infections (CAUTIs), the risks involved with catheter use and how to manage catheters safely.
February 1, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28122873/rising-stakes-for-healthcare-associated-infection-prevention-implications-for-the-clinical-microbiology-laboratory-revised
#6
Daniel J Diekema
Healthcare associated infection (HAI) rates are subject to public reporting, and are linked to hospital reimbursement from the Centers for Medicare and Medicaid Services (CMS). The increasing pressure to lower HAI rates comes at a time when advances in the clinical microbiology laboratory (CML) provide more precise and sensitive tests, altering HAI detection in ways that may increase reported HAI rates. I review how changing CML practices can impact HAI rates, and how the financial implications of HAI metrics may produce pressure to change diagnostic testing practices...
January 25, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28114875/catheter-associated-urinary-tract-infection-cauti-after-term-cesarean-delivery-incidence-and-risk-factors-at-a-multi-center-academic-institution
#7
Laura J Moulton, Mark Lachiewicz, Xiaobo Liu, Oluwatosin Goje
PURPOSE: To identify the rate of CAUTI (catheter-associated urinary tract infection) after CD (Cesarean delivery) and to determine if any factors increase risk of infection. METHODS: A retrospective cohort study was performed at a multi-center institution for patients who underwent CD in 2013. All patients had urinary catheters inserted before surgery. Diagnosis followed IDSA guidelines with culture growing greater than 10(3) CFU of bacteria per mL with symptoms or symptomatic urinary tract infections treated at provider discretion...
January 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28100054/efficacy-of-silver-hydrophilic-poly-p-xylylene-on-preventing-bacterial-growth-and-biofilm-formation-in-urinary-catheters
#8
Hamideh Heidari Zare, Viktorija Juhart, Attila Vass, Gerhard Franz, Dieter Jocham
Catheter associated urinary tract infections (CAUTI), caused by several strains of bacteria, are a common complication for catheterized patients. This may eventually lead to a blockage of the catheter due to the formation of a crystalline or amorphous biofilm. Inhibiting bacteria should result in a longer application time free of complaints. This issue has been investigated using an innovative type of silver-coated catheter with a semipermeable cap layer to prevent CAUTI. In this work, two different types of silver catheters were investigated, both of which were capped with poly(p-xylylene) (PPX-N) and exhibited different surface properties that completely changed their wetting conduct with water...
January 18, 2017: Biointerphases
https://www.readbyqxmd.com/read/28096455/multicenter-prospective-study-on-device-associated-infection-rates-and-bacterial-resistance-in-intensive-care-units-of-venezuela-international-nosocomial-infection-control-consortium-inicc-findings
#9
Gabriel D Empaire, Maria E Guzman Siritt, Victor D Rosenthal, Fernando Pérez, Yvis Ruiz, Claudia Díaz, Gabriela Di Silvestre, Evelyn Salinas, Nelva Orozco
BACKGROUND: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety in the intensive care unit (ICU). METHODS: A DA-HAI surveillance study was conducted by the International Nosocomial Infection Control Consortium (INICC) in two adult medical/surgical ICUs at two hospitals in Caracas, Venezuela, in different periods from March 2008 to April 2015, using the US Centers for Disease Control and Prevention's National Healthcare Safety Network (CDC/NHSN) definitions and criteria, and INICC methods...
January 2017: International Health
https://www.readbyqxmd.com/read/28069123/pepsin-diffusion-in-dairy-gels-depends-on-casein-concentration-and-microstructure
#10
J Thévenot, C Cauty, D Legland, D Dupont, J Floury
Fundamental knowledge of gastric digestion had only focused on acid diffusion from the gastric fluid, but no data are available for pepsin diffusion. Using fluorescence recovery after photobleaching technique, diffusion coefficients D of fluorescein isothiocyanate (FITC)-pepsin were measured in rennet gels across a range of casein concentrations allowing to form networks of protein aggregates with different structures. To investigate the microstructural parameters of native gels, electron microscopy image analysis were performed and qualitatively related to diffusion behavior of FITC-pepsin in these dairy gels...
May 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28057985/the-efficacy-of-noble-metal-alloy-urinary-catheters-in-reducing-catheter-associated-urinary-tract-infection
#11
Alanood Ahmed Aljohi, Hanan Elkefafy Hassan, Rakesh Kumar Gupta
BACKGROUND: Catheter-associated urinary tract infection (CAUTI) is the most common device-related healthcare-acquired infection. CAUTI can be severe and lead to bacteremia, significant morbidity, prolonged hospital stay, and high antibiotic consumption. PATIENTS AND METHODS: In this study, we evaluated the CAUTI-reducing efficacy of noble metal alloy catheters in sixty patients (thirty per group) in the Intensive Care Unit (ICU) at the King Fahad Hospital in Saudi Arabia...
October 2016: Urology Annals
https://www.readbyqxmd.com/read/28052781/inpatient-urine-cultures-are-frequently-performed-without-urinalysis-or-microscopy-findings-from-a-large-academic-medical-center
#12
Abigail L Carlson, Satish Munigala, Anthony J Russo, Kathleen M McMullen, Helen Wood, Ronald Jackups, David K Warren
OBJECTIVE To describe the frequency of urine cultures performed in inpatients without additional testing for pyuria DESIGN Retrospective cohort study SETTING A 1,250-bed academic tertiary referral center PATIENTS Hospitalized adults METHODS This study included urine cultures drawn on 4 medical and 2 surgical wards from 2009 to 2013 and in the medical and surgical intensive care units (ICUs) from 2012 to 2013. Patient and laboratory data were abstracted from the hospital's medical informatics database. We identified catheter-associated urinary tract infections (CAUTIs) in the ICUs by routine infection prevention surveillance...
January 5, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28033847/impact-of-polymicrobial-biofilms-in-catheter-associated-urinary-tract-infections
#13
Andreia S Azevedo, Carina Almeida, Luís F Melo, Nuno F Azevedo
Recent reports have demonstrated that most biofilms involved in catheter-associated urinary tract infections are polymicrobial communities, with pathogenic microorganisms (e.g. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and uncommon microorganisms (e.g. Delftia tsuruhatensis, Achromobacter xylosoxidans) frequently co-inhabiting the same urinary catheter. However, little is known about the interactions that occur between different microorganisms and how they impact biofilm formation and infection outcome...
December 30, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28031194/azithromycin-ciprofloxacin-impregnated-urinary-catheters-avert-bacterial-colonization-biofilm-formation-and-inflammation-in-a-murine-model-of-foreign-body-associated-urinary-tract-infections-caused-by-pseudomonas-aeruginosa
#14
Hina Saini, Anitha Vadekeetil, Sanjay Chhibber, Kusum Harjai
Pseudomonas aeruginosa is a multifaceted pathogen causing a variety of biofilm-mediated infections including catheter-associated urinary tract infections (CAUTIs). High prevalence of CAUTIs in hospitals, their clinical manifestations like urethritis, cystitis, pyelonephritis, meningitis, urosepsis, death; and economic challenges underscore the need for management of these infections. Biomaterial modification of urinary catheters with dual drugs seems an interesting approach to combat CAUTIs by inhibiting biofilm...
December 28, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28025951/optimizing-inpatient-urine-culture-ordering-practices-using-the-electronic-medical-record-a-pilot-study
#15
Daniel Shirley, Harry Scholtz, Kurt Osterby, Jackson Musuuza, Barry Fox, Nasia Safdar
A prospective quasi-experimental before-and-after study of an electronic medical record-anchored intervention of embedded education on appropriate urine culture indications and indication selection reduced the number of urine cultures ordered for catheterized patients at an academic medical center. This intervention could be a component of CAUTI-reduction bundles. Infect Control Hosp Epidemiol 2016;1-3.
December 27, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28001383/luminescent-lanthanide-cyclen-based-enzymatic-assay-capable-of-diagnosing-the-onset-of-catheter-associated-urinary-tract-infections-both-in-solution-and-within-polymeric-hydrogels
#16
Esther M Surender, Samuel J Bradberry, Sandra A Bright, Colin P McCoy, D Clive Williams, Thorfinnur Gunnlaugsson
Herein we present a supramolecular (delayed luminescent) Eu(III)-based pH-responsive probe/sensor with the ability to detect the urease-mediated hydrolysis of urea in aqueous solution. A series of photophysical titrations show this Eu(III) chelate behaves as an "on-off" luminescent switching probe, with its luminescence being quenched upon urea being enzymatically converted into ammonia and carbon dioxide. Calculation of the rate constant (k) and activation energy (Ea) for this hydrolysis reaction are detailed; the results demonstrate a direct observation of enzymatic activity in solution by the sensor...
December 21, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27987067/prophylactic-antibiotic-treatment-following-laparoscopic-robot-assisted-radical-prostatectomy-for-the-prevention-of-catheter-associated-urinary-tract-infections-did-the-aua-guidelines-make-a-difference
#17
Miki Haifler, Yoram Mor, Zohar Dotan, Jacob Ramon, Dorit E Zilberman
We sought to evaluate the effectiveness of the American Urological Association (AUA) antibiotic prophylaxis guidelines in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP). Our prospective registry database was reviewed for all RALP cases. The following variables were evaluated: age, associated comorbidities, body mass index (BMI), total operative time, length of stay (LOS), prostate weight, pathological grade and stage. Until 11/2011, RALP patients were treated with antibiotics administered in the operating room and continued until urethral catheter removal...
December 16, 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/27986361/systematic-review-and-meta-analysis-of-the-effectiveness-of-antiseptic-agents-for-meatal-cleaning-in-the-prevention-of-catheter-associated-urinary-tract-infections
#18
REVIEW
O Fasugba, J Koerner, B G Mitchell, A Gardner
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) are among the most common healthcare-associated infections. Antiseptic cleaning of the meatal area before and during catheter use may reduce the risk of CAUTIs. AIM: To undertake a systematic review of the literature and meta-analysis of studies investigating the effectiveness of antiseptic cleaning before urinary catheter insertion and during catheter use for prevention of CAUTIs. METHODS: Electronic databases were searched to identify randomized controlled trials...
March 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27919427/-lose-the-tube-a-choosing-wisely-initiative-to-reduce-catheter-associated-urinary-tract-infections-in-hospitalist-led-inpatient-units
#19
Hyung J Cho, Steve Khalil, Jashvant Poeran, Madhu Mazumdar, Nathaniel Bravo, Fran Wallach, Brian Markoff, Nathan Lee, Andrew S Dunn
We developed a multidisciplinary initiative, "Lose the Tube," focused on a Choosing Wisely recommendation to decrease catheter-associated urinary tract infection (CAUTI) rates and catheter days. Through an electronic health record catheter identification tool, daily interdisciplinary query, and clinician education, our multifaceted intervention reduced mean per-person catheter days from 3.3 to 2.9, decreased CAUTI rates from 2.85 to 0.32 per 1,000 catheter days, and reduced cost by $32,245.
December 2, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27917728/comparing-catheter-associated-urinary-tract-infection-prevention-programs-between-veterans-affairs-nursing-homes-and-non-veterans-affairs-nursing-homes
#20
Lona Mody, M Todd Greene, Sanjay Saint, Jennifer Meddings, Barbara W Trautner, Heidi L Wald, Christopher Crnich, Jane Banaszak-Holl, Sara E McNamara, Beth J King, Robert Hogikyan, Barbara S Edson, Sarah L Krein
OBJECTIVE The impact of healthcare system integration on infection prevention programs is unknown. Using catheter-associated urinary tract infection (CAUTI) prevention as an example, we hypothesize that US Department of Veterans Affairs (VA) nursing homes have a more robust infection prevention infrastructure due to integration and centralization compared with non-VA nursing homes. SETTING VA and non-VA nursing homes participating in the AHRQ Safety Program for Long-Term Care collaborative. METHODS Nursing homes provided baseline information about their infection prevention programs to assess strengths and gaps related to CAUTI prevention via a needs assessment questionnaire...
December 5, 2016: Infection Control and Hospital Epidemiology
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