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https://www.readbyqxmd.com/read/27891745/cardiac-extracellular-matrix-is-associated-with-adverse-outcome-in-patients-with-chronic-heart-failure
#1
Franz Duca, Caroline Zotter-Tufaro, Andreas A Kammerlander, Adelheid Panzenböck, Stefan Aschauer, Daniel Dalos, Benedikt Köll, Benedikt Börries, Hermine Agis, Renate Kain, Klaus Aumayr, Florian Klinglmüller, Julia Mascherbauer, Diana Bonderman
AIMS: Accumulation of extracellular matrix (ECM) is known to play a crucial role in the pathophysiology of heart failure (HF). However, its prognostic relevance is poorly investigated. METHODS AND RESULTS: A total of 73 HF patients who underwent LV endomyocardial biopsy were enrolled in our study. ECM area was quantified by TissueFAXS and ImageJ software. Patients were followed-up at 6-month intervals. The study endpoint was defined as hospitalization for a cardiac reason and/or cardiac death...
November 27, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27875874/geometries-of-h2s%C3%A2-mi-m-cu-ag-au-complexes-studied-by-rotational-spectroscopy-the-effect-of-the-metal-atom
#2
Chris Medcraft, Dror M Bittner, David P Tew, Nicholas R Walker, Anthony C Legon
Complexes formed between H2S and each of CuI, AgI, and AuI have been isolated and structurally characterised in the gas phase. The H2S⋯MI complexes (where M is the metal atom) are generated through laser vaporisation of a metal rod in the presence of a low concentration of H2S and CF3I in a buffer gas of argon undergoing supersonic expansion. The microwave spectra of six isotopologues of each of H2S⋯CuI, H2S⋯AgI and three isotopologues of H2S⋯AuI have been measured by chirped-pulse Fourier transform microwave spectroscopy...
November 21, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27871798/the-association-of-air-pollution-and-greenness-with-mortality-and-life-expectancy-in-spain-a-small-area-study
#3
Carmen de Keijzer, David Agis, Albert Ambrós, Gustavo Arévalo, Jose M Baldasano, Stefano Bande, Jose Barrera-Gómez, Joan Benach, Marta Cirach, Payam Dadvand, Stefania Ghigo, Èrica Martinez-Solanas, Mark Nieuwenhuijsen, Ennio Cadum, Xavier Basagaña
BACKGROUND: Air pollution exposure has been associated with an increase in mortality rates, but few studies have focused on life expectancy, and most studies had restricted spatial coverage. A limited body of evidence is also suggestive for a beneficial association between residential exposure to greenness and mortality, but the evidence for such an association with life expectancy is still very scarce. OBJECTIVE: To investigate the association of exposure to air pollution and greenness with mortality and life expectancy in Spain...
November 18, 2016: Environment International
https://www.readbyqxmd.com/read/27864855/planar-ptpd3-complex-stabilized-by-three-bridging-silylene-ligands
#4
Makoto Tanabe, Ryohei Yumoto, Tetsuyuki Yamada, Tomoko Fukuta, Tsuyoshi Hoshino, Kohtaro Osakada, Tomoaki Tanase
Heterobimetallic PtPd3 complex supported by three bridging diphenylsilylene ligands, [Pt{Pd(dmpe)}₃(μ-SiPh₂)₃] (1, dmpe = 1,2-bis(dimethylphosphino)ethane), is synthesized from mononuclear Pd and Pt complexes. The hexagonal core, composed of Pt, Pd, and Si atoms, is slightly larger than that of tetrapalladium complex, [Pd{Pd(dmpe)}₃(μ-SiPh₂)₃] (2). Reaction of PhSiH₃ with complex 1 in the presence and absence of Ph₂SiH₂ forms a tetranuclear complex with the silyl and hydride ligands at the Pt center, [PtH(SiPh2H){Pd(dmpe)}₃(μ-SiHPh)₃] (3), and octanuclear complex, [{Pt{Pd(dmpe)}₃(μ-SiHPh)₃}₂(κ²-dmpe)] (5), respectively...
November 19, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27858012/a-simultaneous-disulfide-bond-cleavage-n-s-bialkylation-n-protonation-and-self-assembly-reaction-syntheses-structures-and-properties-of-two-hybrid-iodoargentates-with-thiazolyl-based-heterocycles
#5
Guang-Ning Liu, Ke Li, Qing-Shun Fan, Hui Sun, Xin-Yu Li, Xiao-Nan Han, Yu Li, Zhen-Wei Zhang, Cuncheng Li
Solvothermal reactions of AgI with the vulcanization accelerator 2,2'-dibenzothiazolyl disulfide and hydroiodic acid in alcohols afford two hybrid iodoargentates with one-dimensional structures, namely (Et2mbt)[Ag2I3] (1, Hmbt = 2-mercaptobenzothiazole) and {(Hmbt)[AgI]}n (2). The syntheses of both 1 and 2 involve unprecedented multiple in situ reactions. Specifically, a simultaneous disulfide bond cleavage, N and S donor atoms bialkylation, and self-assembly reaction lead to 1 that contains a discrete N,S-biethylated cation (Et2mbt)(+) and a rare inorganic (Ag2I3)(-) anionic chain, while a simultaneous disulfide bond cleavage, N-protonation and self-assembly reaction affords 2 which features zwitterionic Hmbt molecules coordinating with the opposite side Ag atoms of a neutral inorganic (AgI)n chain via forming Ag-S coordination bonds...
November 18, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27856232/improved-recombinant-antibody-production-by-cho-cells-using-a-production-enhancer-dna-element-with-repeated-transgene-integration-at-a-predetermined-chromosomal-site
#6
Yoshinori Kawabe, Takanori Inao, Shodai Komatsu, Guan Huang, Akira Ito, Takeshi Omasa, Masamichi Kamihira
Chinese hamster ovary (CHO) cells are one of the most useful host cell lines for the production of biopharmaceutical proteins. Although a series of production processes have been refined to improve protein productivity and cost performance, establishing producer cells is still time-consuming and labor-intensive. Recombinase-mediated site-specific gene integration into a predetermined chromosomal locus may enable predictable protein expression, reducing the laborious process of cell screening. We previously developed an accumulative site-specific gene integration system (AGIS) using Cre recombinase and mutated loxP sites for transgene integration and amplification in the CHO cell genome...
November 14, 2016: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/27850218/578-application-of-agi-grading-system-in-critically-ill-patients-a-multicenter-observational-study
#7
Bangchuan Hu, Feng Guo, Lijun Ying, Guoping Ge, Aijun Ding, Yunchao Shi, Changwen Liu, Lei Xu
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27812895/glaucoma-intraocular-pressure-reduction
#8
Alex S Huang, Lilit Minasyan, Robert N Weinreb
Medical treatment is a mainstay for the management of glaucoma (Realini 2011; Marquis and Whitson 2005; Hoyng and van Beek 2000). Intraocular pressure (IOP) lowering has been long recognized as and still represents the primary and most widely employed treatment to prevent glaucomatous vision loss (Musch et al. 2011; Leske et al. 2003; The Advanced Glaucoma Intervention Study (AGIS) 2000). Soon after the recognition that "tension" or IOP was related to glaucoma, pharmacological agents were introduced in the mid-1800s, first with the calabar bean (Realini 2011; Proudfoot 2006)...
November 4, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27771318/diagnosis-of-aortic-graft-infection-a-case-definition-by-the-management-of-aortic-graft-infection-collaboration-magic
#9
O T A Lyons, M Baguneid, T D Barwick, R E Bell, N Foster, S Homer-Vanniasinkam, S Hopkins, A Hussain, K Katsanos, B Modarai, J A T Sandoe, S Thomas, N M Price
OBJECTIVE/BACKGROUND: The management of aortic graft infection (AGI) is highly complex and in the absence of a universally accepted case definition and evidence-based guidelines, clinical approaches and outcomes vary widely. The objective was to define precise criteria for diagnosing AGI. METHODS: A process of expert review and consensus, involving formal collaboration between vascular surgeons, infection specialists, and radiologists from several English National Health Service hospital Trusts with large vascular services (Management of Aortic Graft Infection Collaboration [MAGIC]), produced the definition...
October 19, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27743595/relevance-of-the-plasminogen-system-in-physiology-pathology-and-regeneration-of-oral-tissues-from-the-perspective-of-dental-specialties
#10
Christian Wehner, Klara Janjić, Hermann Agis
Plasmin is a proteolytic enzyme that is crucial in fibrinolysis. In oral tissues, the plasminogen system plays an essential role in physiological and pathological processes, which in addition to fibrinolysis include degradation of extracellular matrix, inflammation, immune response, angiogenesis, tissue remodeling, cell migration, and wound healing. Oral tissues reveal a change in the plasminogen system during pathological processes such as periodontitis, peri-implantitis, or pulpitis, as well as in response to mechanical load...
October 5, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27740552/erratum-journal-of-water-and-health-14-3-549-558-results-of-heavy-metals-and-other-water-quality-levels-in-tap-water-from-%C3%A3-an-sourced-from-a%C3%A4-%C3%A4-da%C3%A4-%C3%A4-mt-a%C3%A4-%C3%A4-%C3%A3-anakkale-turkey-gamze-kilinc-selehattin-yilmaz-muhammet-turkoglu-and-huseyin-erdugan-doi-10-2166
#11
https://www.readbyqxmd.com/read/27738704/-evaluation-of-an-icd-10-based-electronic-surveillance-of-acute-respiratory-infections-seed-ari-in-germany
#12
Karla Köpke, Kerstin Prahm, Silke Buda, Walter Haas
BACKGROUND: Every year epidemic waves of influenza and other acute respiratory infections (ARIs) cause a highly variable burden of disease in the population. Thus, assessment of the situation and adaptation of prevention strategies have to rely on real time syndromic surveillance. OBJECTIVE: We have established an ICD-10-based electronic system allowing rapid capture and transmission of information on ARI (SEED(ARI)), in Germany. Here we report the evaluation of this new system based on results of the syndromic and virologic surveillance carried out by the working group on influenza in Germany (AGI)...
October 13, 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27722672/impact-of-the-si-al-ratio-on-the-selective-capture-of-iodine-compounds-in-silver-mordenite-a-periodic-dft-study
#13
Siwar Chibani, Mouheb Chebbi, Sébastien Lebègue, Laurent Cantrel, Michael Badawi
Silver modified zeolites with a mordenite structure can capture volatile iodine compounds (I2 and ICH3) which can be released during a severe nuclear accident. However under these particular conditions, molecules such as CO and H2O present in the containment atmosphere are expected to inhibit the adsorption of iodine compounds. In the present work, periodic density functional theory calculations have been carried out to investigate the interaction of I2, ICH3, H2O and CO molecules in silver-exchanged mordenite with various Si/Al ratios with the aim of finding values that favor a selective adsorption of I2 and ICH3...
September 14, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27722571/an-oxygen-vacancy-rich-3d-novel-hierarchical-mos2-bioi-agi-ternary-nanocomposite-enhanced-photocatalytic-activity-through-photogenerated-electron-shuttling-in-a-z-scheme-manner
#14
M Jahurul Islam, D Amaranatha Reddy, Noh Soo Han, Jiha Choi, Jae Kyu Song, Tae Kyu Kim
An oxygen-vacancy rich, bismuth oxyiodide-based Z-scheme 3D hierarchical MoS2/BiOI/AgI ternary nanocomposite photocatalyst was fabricated using a simple precipitation process in ethylene glycol and water. The presence of oxygen-vacancies in BiOI and the two-dimensional nature of molybdenum disulfides in the composite prolongs the charge carrier lifetime through a Z-scheme system and enhances the performance of the photocatalyst for the degradation of rhodamine B. On the basis of efficient separation of photoexcited electron-hole pairs, a mechanism is proposed whereby MoS2 and oxygen vacancy states increase charge carrier lifetimes and improve the photocatalytic activity...
September 14, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27711576/dynamics-of-silver-ions-in-agi-doped-ag2o-seo2-moo3-mixed-former-glasses
#15
Arnab Palui, Anirban Shaw, A Ghosh
We have studied the dynamics of silver ions in AgI-doped Ag2O-SeO2-MoO3 mixed former glasses in wide frequency and temperature ranges. We have observed that the ionic conductivity exhibits a mixed glass network former effect for low AgI content. The scaling for the conductivity spectra shows that the mechanism of charge carrier dynamics is independent of temperature and composition. We have obtained a mobile Ag(+) ion concentration from the Nernst-Einstein relation, which is found to be independent of temperature, but slightly dependent on composition...
September 21, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27702802/dynamic-disulfide-thiol-homeostasis-in-lead-exposure-denoted-by-a-novel-method
#16
Ceylan Bal, Erol Rauf Ağış, Meşide Gündüzöz, Murat Büyükşekerci, Murat Alışık, Orhan Şen, Engin Tutkun, Ömer Hınç Yılmaz
Lead is a toxic heavy metal, and prevention of human exposure to lead has not been accomplished yet. The toxicity of lead is continually being investigated, and the molecular mechanisms of its toxicity are still being revealed. In this study, we used a novel method to examine thiol (SH)/disulfide homeostasis in workers who were occupationally exposed to lead. A total of 80 such workers and 70 control subjects were evaluated, and their native and total SH values were measured in serum using a novel method; their blood lead levels were also assessed...
October 3, 2016: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/27701311/one-new-genus-and-three-new-species-of-plumulariid-hydroids-cnidaria-hydrozoa-plumulariidae-from-the-western-pacific-ocean-with-a-re-examination-of-plumularia-insignis-allman-1883-and-related-taxa
#17
José Ansín Agís, Fran Ramil, Dale R Calder
One new genus (Schizoplumularia) and three new species (Schizoplumularia vervoorti, S. geniculata and S. elegans) of plumulariids are recognized and described from large collections of plumularioid hydroids collected in New Caledonia and vicinity during several French expeditions. During taxonomic studies of these hydroids, colonies were compared with type material of Plumularia insignis Allman, 1883 and several other similar species-group taxa. As a result, three of the latter (P. flabellum Allman, 1883, P...
September 19, 2016: Zootaxa
https://www.readbyqxmd.com/read/27694159/low-vaccination-coverage-of-greek-roma-children-amid-economic-crisis-national-survey-using-stratified-cluster-sampling
#18
Dimitris Papamichail, Ioanna Petraki, Chrisoula Arkoudis, Agis Terzidis, Emmanouil Smyrnakis, Alexis Benos, Takis Panagiotopoulos
BACKGROUND: Research on Roma health is fragmentary as major methodological obstacles often exist. Reliable estimates on vaccination coverage of Roma children at a national level and identification of risk factors for low coverage could play an instrumental role in developing evidence-based policies to promote vaccination in this marginalized population group. METHODS: We carried out a national vaccination coverage survey of Roma children. Thirty Roma settlements, stratified by geographical region and settlement type, were included; 7-10 children aged 24-77 months were selected from each settlement using systematic sampling...
October 2, 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27681689/an-investigation-of-the-antiplatelet-effects-of-succinobucol-agi-1067
#19
Stephanie A Houston, Azizah Ugusman, Sukanya Gnanadesikan, Simon Kennedy
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet-platelet and platelet-vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for the antiplatelet activity of succinobucol. Platelet aggregation in response to collagen and adenosine diphosphate (ADP) was studied in rabbit whole blood and platelet-rich plasma using impedance aggregometry. The effect of oxidant stress on aggregation, platelet lipid peroxides, and vascular tone was studied by incubating platelets, washed platelets or preconstricted rabbit iliac artery rings respectively with a combination of xanthine and xanthine oxidase (X/XO)...
September 29, 2016: Platelets
https://www.readbyqxmd.com/read/27619522/photoresponsive-colorimetric-immunoassay-based-on-chitosan-modified-agi-tio2-heterojunction-for-highly-sensitive-chloramphenicol-detection
#20
Honghong Chang, Jia Lv, Haochun Zhang, Bing Zhang, Wenlong Wei, Yan Qiao
Chloramphenicol (CAP) is an antibiotic used for a variety of infections, however, it is banned for use in food-producing animals due to its hazards to humans blood. Herein, the highly sensitive photoresponsive colorimetric immunoassay was exploited based on AgI/TiO2 heterojunction nanomaterials. Firstly, chitosan modified AgI/TiO2 photocatalyst (CS-AgI/TiO2) was synthesized by deposition-precipitation method, which was characterized by transmission electron microscope (TEM), scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray powder diffraction (XRD), UV-Vis diffuse reflectance spectroscopy (DRS) and Fourier transform infrared spectroscopy (FTIR)...
September 2, 2016: Biosensors & Bioelectronics
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