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https://www.readbyqxmd.com/read/29243307/pulmonary-nodules-and-nodular-scleritis-in-a-teenager-with-superficial-granulomatous-pyoderma-gangrenosum
#1
Francisco A Contreras-Verduzco, Sara E Espinosa-Padilla, Luz Orozco-Covarrubias, Adriana Alva-Chaire, César M Rojas-Maruri, Marimar Sáez-de-Ocariz
Superficial granulomatous pyoderma gangrenosum, a rare variant of pyoderma gangrenosum, has been considered to be the most benign form of the disease. We present the case of a 15-year-old boy with pulmonary involvement and nodular scleritis associated with this unusual type of pyoderma gangrenosum and discuss its differential diagnosis.
December 15, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#2
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29095065/anterior-scleritis-associated-with-pemphigus-vulgaris
#3
Tal Zeeli, Efrat Bar-Ilan, Zohar Habot-Wilner, Eli Sprecher
We present a rare co-occurrence of anterior scleritis developing in a patient with recalcitrant pemphigus vulgaris. We discuss the clinical and therapeutic implications of these two conditions and offer concise recommendations.
November 2, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29042820/necrobiotic-xanthogranuloma-scleritis-in-a-case-of-granulomatosis-with-polyangiitis-wegener-s-granulomatosis
#4
Narumon Keorochana, Kanaspana Klanarongran, Kantang Satayasoontorn, Sumapa Chaiamnuay
The purpose of this study was to describe a case of necrobiotic xanthogranuloma scleritis in a 53-year-old male with unilateral progressive visual loss, scleritis, prolonged fever, and multiple mononeuropathy. Scleral biopsy showed necrosis with small abscess, and the pathological tissues revealed submucosal infiltration of mononucleated foamy histiocytes (xanthoma cells), hemosiderin-laden macrophages, neutrophils, lymphocytes, plasma cells, and erythrocytes without Touton giant cells or cholesterol clefts...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29040032/interventions-and-outcomes-in-patients-with-infectious-pseudomonas-scleritis-a-10-year-perspective
#5
Sumayya Ahmad, Michelle Lopez, Marwan Attala, Anat Galor, Natalie A Stanciu, Darlene Miller, Leejee Suh, Thomas Albini, Victor L Perez, Carol L Karp, Janet L Davis, Eduardo Alfonso, Richard K Forster, Guillermo Amescua
PURPOSE: To identify interventional factors associated with improved visual results and faster time to resolution for patients with Pseudomonas scleritis. METHODS: Retrospective study analyzing inciting factors, therapeutic modalities, and outcomes of patients with Pseudomonas scleritis. RESULTS: A total of 24 patients were analyzed; 22 were treated as outpatients. All had resolution of infection and 58% (n = 14) maintained ≥20/200 vision...
October 17, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29023165/clinical-characteristics-of-ocular-sarcoidosis-a-population-based-study-1976-2013
#6
Patompong Ungprasert, Andrea A Tooley, Cynthia S Crowson, Eric L Matteson, Wendy M Smith
PURPOSE: To characterize the epidemiology and clinical characteristics of ocular involvement in patients with systemic sarcoidosis. METHODS: An inception cohort of patients with systemic sarcoidosis in 1976-2013 in Olmsted County, Minnesota, was identified based on comprehensive individual medical record review. Medical records of those patients were then reviewed for ocular involvement. RESULTS: A total of 345 incident cases of systemic sarcoidosis were identified...
October 12, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29020538/orbital-inflammatory-syndrome-post-group-a-streptococcal-infection-case-series-and-review-of-literature
#7
Gilad Rabina, Igal Leibovitch, Muhammad Abumanhal, Amir Rosenblatt, Ran Ben Cnaan
OBJECTIVE: To report new cases of orbital inflammatory syndrome (OIS) post group A streptococcal (GAS) infection and review the literature. METHODS: A retrospective case series of patients with OIS post GAS infection seen in our clinic (from January 2015 to December 2016) and review of additional patients from the literature. RESULTS: A total of nine patients with OIS post GAS infection were included in the study (four patients seen in our clinic and five from previous literature); seven females and two males, three children (under the age of 16), and six adults...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28990976/orbital-inflammation-as-a-presenting-sign-for-crest-syndrome
#8
Shirin W Hamed-Azzam, David P D'Cruz, David H Verity
A 61-year-old male was referred with a week's history of a painful and swollen left eye. Examination revealed normal visual acuities, left proptosis and global restriction of ocular ductions, and subretinal fluid at the macula. CT imaging confirmed thickening of the posterior scleral coat, with an associated choroidal effusion. Serology revealed positive antinuclear antibodies with a centromere staining pattern; subsequent rheumatology review revealed extensive telangiectasia with digital ulceration in both hands, and a diagnosis of limited cutaneous systemic sclerosis was made...
September 27, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28981391/posterior-scleritis-with-choroidal-effusion-secondary-to-herpes-zoster-ophthalmicus
#9
Edmund Tsui, Soshian Sarrafpour, Yasha S Modi
PURPOSE: To describe a case of posterior scleritis with serous choroidal detachment that occurred as an acute complication of herpes zoster ophthalmicus (HZO). METHODS: Retrospective case report. RESULTS: A 75-year-old female presented with 3 days of painful, decreased vision in her left eye 1 week after being diagnosed with HZO. She had unilateral crusted vesicular lesions in the V1 dermatomal distribution and corneal pseudodendrites. Funduscopic examination demonstrated a large choroidal detachment in her left eye...
October 5, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28978606/sclerokeratouveitis-and-lens-dislocation-in-a-patient-with-genital-ulcer-was-the-great-imitator-imitated
#10
Anubha Rathi, Brijesh Takkar, Namrata Sharma
Uveitis is the most common ocular manifestation of syphilis, while scleritis is rare. A case of nodular scleritis, peripheral keratitis and uveitis in a patient with genital ulcer is presented in this report. This patient had a clinical profile suggestive of syphilis, though the serology was negative for treponemal antibodies. Other possible differential diagnosis imitating syphilis are discussed.
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28957561/clinical-characteristics-of-inflammatory-ocular-disease-in-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis-a-retrospective-cohort-study
#11
Patompong Ungprasert, Cynthia S Crowson, Rodrigo Cartin-Ceba, James A Garrity, Wendy M Smith, Ulrich Specks, Eric L Matteson, Ashima Makol
Objective: To characterize the clinical correlates and outcome of inflammatory ocular disease (IOD) among patients with ANCA-associated vasculitides (AAV). Methods: Medical records of potential cases of AAV seen at Mayo Clinic from 2003 to 2013, inclusive, were reviewed to identify confirmed cases meeting the diagnosis of AAV using the Chapel Hill Consensus Conference 2012 descriptors. Records of confirmed cases of AAV were then further reviewed for IOD, and clinical characteristics, treatment and outcomes abstracted...
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28932076/ophthalmic-manifestations-in-patients-with-inflammatory-bowel-disease-a-review
#12
REVIEW
Leandro Lopes Troncoso, Ana Luiza Biancardi, Haroldo Vieira de Moraes, Cyrla Zaltman
Clinical manifestations of inflammatory bowel disease (IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in PubMed, was performed. Episcleritis, the most common ocular extraintestinal manifestation (EIM), seems to be more associated with IBD activity when compared with other ocular EIMs...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28924436/pseudomonas-scleritis-following-pterygium-excision
#13
Winai Chaidaroon, Sumet Supalaset
PURPOSE: The aim of this case report was to describe a patient who presented with Pseudomonas scleritis after pterygium excision. The study was conducted at the Department of Ophthalmology, Faculty of Medicine, Chiang Mai University in Chiang Mai, Thailand. METHODS: The record of a patient who was diagnosed as Pseudomonas scleritis after pterygium excision was retrospectively reviewed for history, clinical characteristics, laboratory findings, treatments, and outcomes...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28916114/-scleritis-and-episcleritis
#14
REVIEW
E Héron, T Bourcier
Episcleritis is generally a benign disease with a self-limited course, while scleritis is a severe ocular condition due to a risk of impaired vision in one-fifth of patients and its association with systemic diseases in one third of them. Infectious scleritis, representing 8 % of the etiologies, is mainly of herpetic origin (varicella zoster and herpes simplex viruses). A systemic autoimmune disease is observed in roughly 30 % of scleritis patients: inflammatory rheumatisms (15 %), firstly rheumatoid polyarthritis, systemic vasculitides (8 %), mainly granulomatosis with polyangiitis (Wegener's) and polychondritis, and less often inflammatory bowel disease and systemic lupus erythematosus...
October 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28914559/bilateral-posterior-scleritis-associated-with-giant-cell-arteritis-a-case-report
#15
Mehmet Erdogan, Nihat Sayin, Dilbade Yıldız Ekinci, Sadik Bayramoglu
AIM: To report a case of bilateral posterior scleritis associated with giant cell arteritis Case Report: A 62-year-old female patient presented with bilateral progressive vision loss was diagnosed with bilateral posterior scleritis. According to clinical signs and symptoms and laboratory testing, Giant cell arteritis was also diagnosed. Within 8 weeks of the corticosteroid treatment, the serous retinal detachments completely resolved and choroidal thickness decreased in both eyes. Visual acuity increased, and the symtoms related to Giant cell arteritis improved...
September 15, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28910555/conjunctival-necrosis-masquerading-as-necrotizing-scleritis
#16
Mamta Agarwal, Amala Elizabeth, Ronnie George, Jyotirmay Biswas
No abstract text is available yet for this article.
September 14, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28903964/clinical-profile-of-pythium-keratitis-perioperative-measures-to-reduce-risk-of-recurrence
#17
Shweta Agarwal, Geetha Iyer, Bhaskar Srinivasan, Mamta Agarwal, Shobha Panchalam Sampath Kumar, Lily K Therese
PURPOSE: To report the clinical profile and role of perioperative adjunctive measures to reduce the risk of recurrence in Pythium insidiosum keratitis. METHODS: Retrospective analysis of 10 eyes of 10 patients with P. insidiosum keratitis. Diagnosis was confirmed by PCR DNA sequencing. RESULTS: 7out of 10 patients were from urban locales, and none had any obvious history of injury with vegetative matter and were being treated for fungal keratitis...
September 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28886929/indocyanine-green-angiography-in-anterior-scleritis
#18
M C Garcia-Saenz, C Del Prado Sánchez, L Lloreda Martin, J Bañuelos Bañuelos
No abstract text is available yet for this article.
September 5, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28871936/xanthoma-like-skin-changes-in-an-elderly-woman-with-a-normal-lipid-profile
#19
Piotr Nockowski, Zdzisław Woźniak, Adam Reich, Joanna Maj
Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Imaging assessment and ultrasound examination did not show any specific involvement of internal organs...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28858963/igg4-related-disease-in-the-eye-and-ocular-adnexa
#20
REVIEW
Larissa Derzko-Dzulynsky
PURPOSE OF REVIEW: IgG4-related disease is a multi-organ fibro-inflammatory disease with characteristic histopathology showing lymphoplasmacytic infiltration, increased IgG4+ plasma cells and elevated IgG4/IgG ratios (>40%). The lacrimal gland is the most common ocular site of involvement. Scleritis and intraocular involvement in IgG4-related ophthalmic disease (IgG4-ROD) have recently been reported. The purpose of this review is to describe orbital and intraocular IgG4-ROD with a focus on publications since 2016...
November 2017: Current Opinion in Ophthalmology
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