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https://www.readbyqxmd.com/read/27871395/bilateral-scleritis-and-retinal-vasculitis-in-microscopic-polyangiitis
#1
David Diaz-Valle, Alejandro Gomez-Gomez, Alejandro Pascual-Martin
No abstract text is available yet for this article.
December 2016: Ophthalmology
https://www.readbyqxmd.com/read/27853018/infectious-pseudomonas-and-bipolaris-scleritis-following-history-of-pterygium-surgery
#2
Ashkan M Abbey, Nisha V Shah, Richard K Forster, Leejee H Suh
We report an interesting case of infectious scleritis from coinfection of Pseudomonas aeruginosa and Bipolaris with no corneal infiltrate. A healthy 60-year-old man with a history of infectious scleritis following pterygium excision presented with purulent material growing P. aeruginosa and 1+ colonies of Bipolaris species of fungus. Broad spectrum treatment was initiated with hourly topical moxifloxacin, fortified tobramycin, and natamycin along with a subconjunctival injection of voriconazole and topical cyclosporine, with PO ketoconazole...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27849414/clinical-features-and-complications-of-scleritis-in-chinese-patients
#3
Peizeng Yang, Zi Ye, Jihong Tang, Liping Du, Qingyun Zhou, Jian Qi, Liang Liang, Lili Wu, Chaokui Wang, Mei Xu, Yuan Tian, Aize Kijlstra
PURPOSE: To characterize the clinical features of scleritis in Chinese patients. METHODS: The history, demographics, ocular findings, auxiliary examination findings, complications, systemic diseases and therapeutic effects were analyzed retrospectively. RESULTS: The study included 124 male and 169 female patients with scleritis. Anterior and posterior scleritis were, respectively, found in 243 and 42 patients. The other eight patients had both anterior and posterior involvement...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27825329/intravitreal-dexamethasone-implants-for-the-treatment-of-refractory-scleritis-combined-with-uveitis-in-adult-onset-still-s-disease-a-case-report
#4
Seong Joon Ahn, Sun Jin Hwang, Byung Ro Lee
BACKGROUND: Adult-onset Still's disease is a systemic inflammatory disease which presents with uveitis and scleritis in the eye. Intravitreal dexamethasone implants are used for the treatment of refractory uveitis. CASE PRESENTATION: A 19-year-old woman diagnosed to have adult-onset Still's disease for fevers, joint pain, and a salmon-colored bumpy rash presented with scleritis and uveitis in the left eye. Topical and systemic steroids with oral methotrexate failed to control the inflammation...
November 8, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27775456/a-case-of-necrobiotic-xanthogranuloma-presenting-as-bilateral-posterior-scleritis
#5
Alenka Lavric, Rupesh Agrawal, Carlos Pavesio
No abstract text is available yet for this article.
October 24, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27772649/scleritis-with-devastating-consequences
#6
Meisha L Raven, Christopher K H Burris, Heather D Potter
No abstract text is available yet for this article.
November 2016: Ophthalmology
https://www.readbyqxmd.com/read/27769331/purpureocillium-lilacinum-keratitis-a-case-series-and-review-of-the-literature
#7
Rusheng Chew, Andrew Dorman, Marion L Woods
OBJECTIVE: To describe the clinical features and risk factors of and optimal antifungal therapy for Purpureocillium lilacinum keratitis. DESIGN: Retrospective case series in a quaternary referral hospital setting. METHODS: Comprehensive chart review of patients diagnosed with P. lilacinum keratitis in the past 10 years. PARTICIPANTS: Four patients were identified. All were aged 60 years or greater, with none having prior ocular trauma...
October 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27762661/clinical-profile-of-patients-with-necrotizing-scleritis-in-a-tertiary-eye-care-center-in-southern-india
#8
Parthopratim Dutta Majumder, Avirupa Ghose, Meenakshi Chidambaram, Sudha K Ganesh, Jyotirmay Biswas
PURPOSE: To report the clinical profile of a series of necrotizing scleritis in an Indian population. METHODS: A retrospective medical record review of 27 consecutive patients with necrotizing scleritis. Patient demographics, ocular and systemic findings, treatment modalities, and visual outcome were recorded. RESULTS: There were 19 males and 8 females (31 eyes) with mean age at presentation of 49.5 years (range: 30-84 years). Underlying immunologically induced disorders was present in 37%...
October 20, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27749454/nodulo-ulcerative-ocular-surface-squamous-neoplasia-in-6-patients-a-rare-presentation
#9
Swathi Kaliki, Suzanne K Freitag, James Chodosh
PURPOSE: To describe clinical presentation and histopathological features of a nodulo-ulcerative variant of ocular surface squamous neoplasia (OSSN). METHODS: Retrospective study. RESULTS: Six patients were identified with a nodulo-ulcerative variant of OSSN. Mean age at presentation was 56 years. One patient was immunosuppressed because of human immunodeficiency virus infection. The initial misdiagnosis was necrotizing scleritis/sclerokeratitis (n = 4), intraepithelial neoplasia (n = 1), and chalazion (n = 1)...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27744531/uveitis-specialists-and-rheumatologists-select-different-therapies-for-idiopathic-non-necrotizing-anterior-scleritis
#10
Daniel J Ozzello, Jason R Kolfenbach, Alan G Palestine
INTRODUCTION: Uveitis specialists and rheumatologists treat patients with anterior scleritis, but data from controlled trials to guide management are scarce, making differences in treatment paradigms possible. METHODS: 1044 uveitis specialists and rheumatologists were surveyed regarding therapy for a patient with anterior scleritis. Respondents were asked to select first- and second-choice therapies and then reselect therapies assuming that the costs of all options were equal and that insurance approval was ensured...
October 15, 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27663070/gevokizumab-in-the-treatment-of-autoimmune-non-necrotizing-anterior-scleritis-results-of-a-phase-i-ii-clinical-trial
#11
Jared E Knickelbein, William R Tucker, Nirali Bhatt, Karen Armbrust, David Valent, Dominic Obiyor, Robert B Nussenblatt, H Nida Sen
PURPOSE: To evaluate the safety and potential efficacy of gevokizumab, an anti-interleukin 1β (IL-1β) monoclonal antibody, in the treatment of active, noninfectious, non-necrotizing anterior scleritis. DESIGN: Phase 1/2, open label, nonrandomized, prospective, single-arm pilot trial. METHODS: Eight patients with active, noninfectious, non-necrotizing anterior scleritis with a scleral inflammatory grade of +1 to +3 in at least 1 eye were enrolled...
September 20, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27646473/latent-tuberculosis-related-scleritis-a-case-report
#12
Houssaine Ait Lhaj, Amine Benjelloun, Youssef Bouia, Youssef Bennouk, Yassine Mouzari, Youssef El Kamouni, Mohamed Kriet
BACKGROUND: Scleritis is a painful inflammatory process centered in the sclera that may involve the cornea and the underlying uvea. The etiology is commonly idiopathic or autoimmune but some cases are associated with systemic infection such as tuberculosis. CASE PRESENTATION: In this report, we describe an unusual case of a female Moroccan patient who had a long history of bilateral recurrent scleritis associated with peripheral keratopathy and anterior uveitis...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/27550224/-diagnosis-and-treatment-of-episcleritis-and-scleritis
#13
C Tappeiner, K Walscheid, A Heiligenhaus
Episcleritis is a benign and self-limiting disease, often with a recurrent course, manifesting mainly in young adults. In less than a third of patients, an associated systemic disease can be found. In contrast, scleritis is observed mainly in patients between the 4th and 6th decade of life, may lead to severe ocular complications, and is often associated with a systemic rheumatological disease. Diffuse, nodular, and necrotizing forms of scleritis can be differentiated. Necrotizing and posterior scleritis have a higher risk of complications and worse visual outcome...
September 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27538451/ocular-toxocariasis-presenting-as-bilateral-scleritis-with-suspect-retinal-granuloma-in-the-nerve-fiber-layer-a-case-report
#14
Kang Yeun Pak, Sung Who Park, Ik Soo Byon, Ji Eun Lee
BACKGROUND: This report details ocular toxocariasis presenting as bilateral scleritis with suspect retinal granuloma in the nerve fiber layer. CASE PRESENTATION: The patient presented with scleritis, which did not improve with systemic steroid. Intraocular pressure was elevated, and well demarcated hyper-reflective round lesion were noted in both eyes. He had a history of general ache and concurrent onset of ocular symptoms the day after eating raw meat. Systemic work-ups revealed no remarkable abnormalities except antibody for toxocara...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27495133/trigeminal-autonomic-cephalgia-caused-by-recurrent-posterior-scleritis
#15
Ali Alim-Marvasti, Jason Ho, Mark Weatherall, Maneesh Patel, Sheena George, Stuart Viegas
A 40-year-old woman presented with a side-locked headache with autonomic features, which then switched sides before reverting to the original side. The atypical features of side swapping, partial response to indometacin and abnormal optic disc appearances ultimately led to a diagnosis of recurrent posterior scleritis. We discuss the differential diagnosis of trigeminal autonomic cephalgias and its secondary causes, and provide practical pointers for its investigation and management.
August 5, 2016: Practical Neurology
https://www.readbyqxmd.com/read/27493788/paradoxical-reactions-under-tnf-%C3%AE-blocking-agents-and-other-biological-agents-given-for-chronic-immune-mediated-diseases-an-analytical-and-comprehensive-overview
#16
REVIEW
Éric Toussirot, François Aubin
Paradoxical adverse events (PAEs) have been reported during biological treatment for chronic immune-mediated diseases. PAEs are defined as the occurrence during biological agent therapy of a pathological condition that usually responds to this class of drug. A wide range of PAEs have been reported including dermatological, intestinal and ophthalmic conditions, mainly with antitumour necrosis factor α (TNF-α) agents. True PAEs include psoriasis, Crohn's disease and hidradenitis suppurativa. Other PAEs may be qualified as borderline and include uveitis, scleritis, sarcoidosis and other granulomatous diseases (granuloma annulare, interstitial granulomatous dermatitis), vasculitis, vitiligo and alopecia areata...
2016: RMD Open
https://www.readbyqxmd.com/read/27485819/multifocal-surgically-induced-necrotizing-scleritis-following-strabismus-surgery-a-case-report
#17
Mohammad Reza Akbari, Masoomeh Mohebbi, Mohammadkarim Johari, Arash Mirmohammadsadeghi, Alireza Mahmoudi
PURPOSE: To present clinical findings of a 28-year-old woman with multifocal surgically induced necrotizing scleritis following uncomplicated strabismus surgery. METHOD: A 28-year-old woman underwent uncomplicated strabismus surgery of her right eye for sensory exotropia under general anesthesia (6 mm right medial rectus muscle resection and 8 mm right lateral rectus muscle recession). DESIGN: Retrospective, observational case report and literature review...
September 2016: Strabismus
https://www.readbyqxmd.com/read/27472515/tarantula-hair-associated-panuveitis-treated-with-sustained-release-intravitreal-dexamethasone-implant
#18
Melina I Morkin, Lana M Rifkin, Sabin Dang, Caroline R Baumal
PURPOSE: To report a case of tarantula hair-induced panuveitis treated with sustained-release intravitreal dexamethasone implant and followed by sequential spectral domain optical coherence tomography imaging. METHODS: Findings on clinical examination, anterior segment optical coherence tomography, corneal in vivo confocal microscopy, color fundus photos, fluorescein angiography, and retinal spectral domain optical coherence tomography are presented. Sequential optical coherence tomography images demonstrated the course of the chorioretinal lesions before and after sustained-release intravitreal dexamethasone implant...
July 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27468098/-intraocular-inflammation-autoimmune-or-infectious
#19
C Auw-Hädrich, S Heinzelmann, S Coupland
Presentation of 3 cases of intraocular inflammation: 1. 47-year old female patient with severe necrotising scleritis and uveitis with underlying granulomatous polyangiitis (formerly known as Wegener granulomatosis, in honour of the German pathologist Friedrich Wegener), known for 10 years. 2. 48-year old male patient with longstanding bilateral uveitis and granulomatous polyangiitis for 2 years. In the histopathological examination of the enucleation specimen, a retrolental tumour turned out to be a granuloma...
July 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27444937/ct-and-mr-imaging-in-the-diagnosis-of-scleritis
#20
M C Diogo, M J Jager, T A Ferreira
Scleritis is a rare, underdiagnosed vision-threatening condition that can occur isolated or in association with other orbital abnormalities. The etiology of scleritis is mainly inflammatory noninfectious, either idiopathic or in the context of systemic disease. Ultrasonography remains the criterion standard in diagnostic imaging of this condition but might prove insufficient, and studies on the diagnostic value of CT and MR imaging are lacking. We retrospectively analyzed 11 cases of scleritis in which CT and/or MR imaging were performed during the active phase of disease and assessed the diagnostic utility of these techniques...
July 21, 2016: AJNR. American Journal of Neuroradiology
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