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https://www.readbyqxmd.com/read/28816763/mammography-findings-of-breast-calcinosis-in-a-patient-with-dermatomyositis
#1
Veenu Singla, Nidhi Prabhakar, Tulika Singh, Aman Sharma, Niranjan Khandelwal
No abstract text is available yet for this article.
August 14, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28779847/efficacy-of-intralesional-sodium-thiosulfate-injections-for-disabling-tumoral-calcinosis-two-cases
#2
J Goossens, M Courbebaisse, E Caudron, C Bahans, V Vacquerie, J Melchior, P Vergne Salle, C Moesch, M Daudon, V Frocht, P Richette, Hang-Korng Ea, V Guigonis
INTRODUCTION: Tumoral calcinosis (TC) is a difficult-to-treat complication that can occur during several diseases such as dermatomyositis or genetic hyperphosphatemia. It is a painful and disabling condition that can lead to local complications including joint mobility reduction, cutaneous ulceration and superinfection. For the largest lesions, the treatment relies essentially on surgery. Intravenous sodium thiosulfate (STS) is efficient to treat calciphylaxis in patients undergoing hemodialysis...
June 17, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28771811/idiopathic-calcinosis-cutis-universalis-treated-successfully-with-oral-diltiazem-a-case-report
#3
Jayanti Singh, Vijay K Paliwal, Puneet Bhargava, Deepak K Mathur
Idiopathic calcinosis cutis is very rare and difficult to treat. Various medical modalities of treatment described with inconsistent results include chelating agents, colchicine, and probenecid. Calcium channel blockers are known to work by inhibiting intracellular entry of calcium. We successfully treated a case of idiopathic calcinosis cutis using oral diltiazem.
August 2, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28764177/idiopathic-tumoral-calcinosis-rare-clinico-pathological-entity-a-report-of-two-cases
#4
Sreedevi Jakka, Radhika Narayan, Minakshi Mishra, Farah Rana, J K Laik
Tumoral calcinosis is a rare disease reported mainly in blacks of tropical and subtropical African regions. It is characterized by tumour-like periarticular deposits of calcium that are found in the regions of the hip, shoulder, elbow and small joints of hands and feet. The involvement of this disease in a healthy patient is extremely rare in young and middle aged individuals. We are presenting two cases with large, painless periarticular swellings in subscapular joint and feet. First case presented with recurrent swelling in different anatomical locations at different time intervals involving the hip and followed by shoulder joint...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28752990/quartz-crystal-microbalance-assay-of-clinical-calcinosis-samples-and-their-synthetic-models-differentiates-the-efficacy-of-chelation-based-treatments
#5
Fan Fei, Andrzej Gallas, Yun-Chuan Chang, Yikun Rao, Alan Christy Hunter, Richard E P Winpenny, Ariane Herrick, Nicholas P Lockyer, Christopher Francis Blanford
This paper sets out in vitro protocols for studying the relative effectiveness of chelators used in the dissolution-based treatment of hard calcinosis. Pulverized hard calcinosis samples from human donors or synthetic hydroxyapatite nanoparticles were deposited by electrophoretic deposition on the surface of a quartz crystal microbalance sensor. Over 150 deposits of <20 µg were dissolved over the course of an hour by aliquots of buffered, aqueous solutions of two calcium chelators, EDTA and citrate, with the surface-limited dissolution kinetics monitored with <1s time resolution...
July 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28722530/are-there-risk-factors-for-scleroderma-related-calcinosis
#6
Sneha Pai, Vivien Hsu
OBJECTIVES: Pathogenesis and risk factors of scleroderma associated calcinosis is poorly understood and there is no effective treatment. This study was performed to better understand the prevalence and clinical features associated with calcinosis in a cohort of SSc outpatients. METHODS: In this cross-sectional study, we compared clinical characteristics of SSc patients with (SSc-calcinosis) and without calcinosis (SSc-control) seen in the outpatient Rutgers-RWJ Scleroderma Program between 2012 and 2015...
July 19, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28685324/phenotypic-characteristics-and-outcome-of-juvenile-dermatomyositis-in-arab-children
#7
Sulaiman M Al-Mayouf, Nora AlMutiari, Mohammed Muzaffer, Rawiah Shehata, Adel Al-Wahadneh, Reem Abdwani, Safia Al-Abrawi, Mohammed Abu-Shukair, Zeyad El-Habahbeh, Abdullah Alsonbul
This study describes the disease characteristics and outcome of Arab children with juvenile dermatomyositis (JDM) and compares the findings with other ethnicities. We retrospectively reviewed the hospital registries of the participating hospitals for children with JDM seen between 1990 and 2016 in three Arab countries. All patients fulfilled Bohan and Peter criteria for JDM, diagnosed before 14 years of age and were of Arab ethnicity. Clinical and laboratory features as well as the long-term outcomes including accrual disease damage were collected at the last follow-up visit...
July 6, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28670092/invited-commentary-calcinosis-cutis-and-renal-disease-an-evolving-story
#8
EDITORIAL
Andrew Z Fenves, Daniela Kroshinsky
No abstract text is available yet for this article.
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28670091/metastatic-calcinosis-cutis-in-end-stage-renal-disease
#9
Victoria A Jaeger, Megan G Newman, Curtis R Mirkes
Alterations in calcium and phosphorus levels and joint pain are a common occurrence in end-stage renal disease patients. However, metastatic calcinosis cutis is a rare diagnosis that often combines these two findings, with extensive soft tissue calcification surrounding a large joint being the hallmark of this disease. The exact mechanism behind this clinical entity is unknown. The treatment and complications can be severe and disabling. Here, we discuss the case of a 26-year-old man presenting with unusually advanced skin and joint calcification of the shoulders, neck, hand, and penis...
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28667747/lack-of-response-to-intravenous-sodium-thiosulfate-in-three-cases-of-extensive-connective-tissue-disease-associated-calcinosis-cutis
#10
P Song, N M Fett, J Lin, J F Merola, M Costner, R A Vleugels
Dystrophic calcinosis cutis is a debilitating condition of calcium salt deposition in the skin often occurring in association with connective tissue disease (CTD). Available treatments for calcinosis cutis are unsatisfactory, but given the recent use of topical and intralesional sodium thiosulfate (STS) to treat calcifying disorders, we sought to describe the use of intravenous (IV) STS for CTD-associated dystrophic calcinosis cutis. We report three patients with longstanding and extensive CTD-associated calcinosis cutis treated with IV STS after having failed multiple prior therapies...
July 1, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28667736/infantile-tumoral-calcinosis
#11
Lavleen Singh, Amitabh Singh, Sataroopa Mishra
No abstract text is available yet for this article.
June 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28654465/high-velocity-paint-gun-injuries
#12
Wendi E Wohltmann, Joshua A Wisell, Celina M C Lafrades, Daniel M Cramer, Bruce D Ragsdale
Cutaneous injuries due to industrial high-pressure paint guns are well-documented in the literature; however, the histologic characteristics are uncommonly described, and facial involvement has not been previously reported. Histopathologic features of paint gun injuries vary depending on the time since injection and type of material. Early lesions display an acute neutrophilic infiltrate, edema, and thrombosis, with varying degrees of skin, fat, and muscle necrosis. More developed lesions (120-192 hours after injury) have prominent histiocytes and fibrosis around necrotic foci, possibly with the pitfall of muscle regenerative giant cells that could be mistaken for sarcoma...
August 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28638697/breast-calcinosis-in-a-patient-with-dermatomyositis
#13
Rajaie Namas, Nassar Beydoun, Alireza Meysami
No abstract text is available yet for this article.
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28626193/uremic-tumoral-calcinosis-resolved-by-improvements-in-hyperphosphatemia
#14
Hirofumi Watanabe, Ryo Koda, Noriaki Iino, Ichiei Narita
No abstract text is available yet for this article.
2017: Internal Medicine
https://www.readbyqxmd.com/read/28613118/initial-experience-with-a-new-quantitative-assessment-tool-for-fluorescent-imaging-in-peripheral-artery-disease
#15
Henrik Christian Rieß, Anna Duprée, Christian-Alexander Behrendt, Tilo Kölbel, Eike Sebastian Debus, Axel Larena-Avellaneda, Detlef Russ, Sabine Wipper
BACKGROUND: Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluorescent imaging (ICG-FI) before and after peripheral bypass grafting...
June 14, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28605526/anti-nxp2-antibody-associated-extensive-subcutaneous-calcinosis-in-adult-onset-myositis
#16
Radjiv Goulabchand, Philippe Guilpain, Catherine Cyteval, Alain Le Quellec
No abstract text is available yet for this article.
June 12, 2017: Rheumatology
https://www.readbyqxmd.com/read/28603937/idiopathic-scrotal-calcinosis-diagnosed-by-fine-needle-aspiration-cytology-report-of-a-rare-case
#17
Nibedita Sahoo, Madhusmita Sethy, Pritinanda Mishra, Susama Patra, Suvendu Purkait, Sanjay Kumar Giri
No abstract text is available yet for this article.
June 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28585220/inherited-arterial-calcification-syndromes-etiologies-and-treatment-concepts
#18
REVIEW
Yvonne Nitschke, Frank Rutsch
PURPOSE OF REVIEW: We give an update on the etiology and potential treatment options of rare inherited monogenic disorders associated with arterial calcification and calcific cardiac valve disease. RECENT FINDINGS: Genetic studies of rare inherited syndromes have identified key regulators of ectopic calcification. Based on the pathogenic principles causing the diseases, these can be classified into three groups: (1) disorders of an increased extracellular inorganic phosphate/inorganic pyrophosphate ratio (generalized arterial calcification of infancy, pseudoxanthoma elasticum, arterial calcification and distal joint calcification, progeria, idiopathic basal ganglia calcification, and hyperphosphatemic familial tumoral calcinosis; (2) interferonopathies (Singleton-Merten syndrome); and (3) others, including Keutel syndrome and Gaucher disease type IIIC...
August 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28576700/tumoral-calcinosis-diffuse-multifocal-form-in-hemodialysis-patients-two-case-reports
#19
D Ibrahim Montasser, J Issouani, Mohamed Hassani, D Kabbaj
Orthopedic surgeons are often consulted for diagnosis of MASS (mitral valve prolapse, aortic enlargement, skin and skeletal findings) syndrome, imaging showing periarticular calcification, or joint stiffness. Such presentations in a dialyzed patient should suggest tumoral calcinosis, which is a rare complication of dialysis, often diagnosed wrongly or late. It is often associated with calcium phosphate balance disorder, in which treatment is difficult and must take account of known contributing factors: severe hyperparathyroidism, increased phosphocalcic product, therapeutic calcium and vitamin D overload, and bone turnover slowed for varying reasons...
May 30, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28564698/intralesional-sodium-thiosulfate-treatment-for-calcinosis-cutis-in-the-setting-of-lupus-panniculitis
#20
Nicole S Gunasekera, Lia E Gracey Maniar, Cecilia Lezcano, Alvaro C Laga, Joseph F Merola
No abstract text is available yet for this article.
May 31, 2017: JAMA Dermatology
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