keyword
MENU ▼
Read by QxMD icon Read
search

Perioperative chemotherapy

keyword
https://www.readbyqxmd.com/read/28938509/-esophageal-adenocarcinoma-appraisal-of-a-rapidly-increasing-disease
#1
Jens Hoeppner, Torben Glatz, Rainer Claus, Andreas Fischer, Klaus Kraywinkel, Thomas Brunner
The incidence of esophageal adenocarcinoma is dramatically increasing in several Western countries. In Germany, the incidence increased by sevenfold since 1991. The most important risk factors for esophageal adenocarcinoma are gastroesophageal reflux and obesity. Early diagnosis is possible within surveillance programs for Barrett metaplasia. Endoscopic resection is effective for diagnosis and curative treatment of early carcinoma. Esophagectomy is the central curative treatment modality for non-metastasized tumors exceeding the mucosal layer...
September 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28935346/resection-of-the-tracheobronchial-bifurcation-with-complete-preservation-of-lung-parenchyma
#2
Georgios Stamatis, Sylvia Fechner, Miguel Rocha, Gerhard Weinreich
BACKGROUND: The resection of the tracheobronchial bifurcation with complete preservation of lung parenchyma remains a challenge owing to the limited indications for surgery, anesthesiologic management, operative technique, and postoperative course. The aim of this retrospective study was to evaluate factors influencing the perioperative course and long-term survival. METHODS: Between 1989 and 2014, 19 patients underwent a resection of the distal trachea and carina with complete preservation of lung tissue, 16 for malignant tumors (7 adenoid cystic carcinomas, 3 carcinoid tumors, 3 mucoepidermoid tumors, 2 squamous cell carcinomas, and 1 small cell carcinomas), 2 for inflammatory stenosis, and 1 after a complex traumatic rupture...
September 18, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28927119/effect-of-glutamine-enriched-nutritional-support-on-intestinal-mucosal-barrier-function-mmp-2-mmp-9-and-immune-function-in-patients-with-advanced-gastric-cancer-during-perioperative-chemotherapy
#3
Juan Wang, Yanfen Li, Yuanling Qi
We studied the effects of glutamine-enriched nutritional support on intestinal mucosal barrier, matrix metalloproteinase (MMP)-2, MMP-9 and immune function during perioperative chemotherapy in patients with advanced gastric cancer. The study was conducted on 94 patients with advanced gastric cancer admitted from April 2015 to March 2016. They were randomly divided into observation and control groups, n=47. Control group was given basic nutritional support whereas glutamine-enriched nutritional support was given to patients in observation group...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28925798/laparoscopic-resections-of-colorectal-cancer-and-synchronous-liver-metastases-a-case-controlled-study
#4
Xiao Xu, Yulin Guo, Guijin Chen, Chen Li, Hongguang Wang, Guanglong Dong
PURPOSE: To investigate the efficacy and safety of laparoscopic simultaneous resections of colorectal cancer and synchronous colorectal liver metastases (SCRLM), relative to open surgery. METHODS: Between 1 January 2009 and 20 April 2014, 20 of 25 patients who underwent laparoscopic simultaneous colorectal cancer and SCRLM resections were matched with 20 of 29 patients who underwent an open approach, based on prognostic propensity scores. Perioperative results and survival outcomes were compared...
September 19, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28925039/clinical-predictive-factors-of-long-term-survival-after-curative-resection-of-pancreatic-cancer-a-retrospective-study
#5
Yutaka Nakano, Minoru Kitago, Masahiro Shinoda, Yuta Abe, Hiroshi Yagi, Taizo Hibi, Ayano Takeuchi, Koichi Aiura, Osamu Itano, Yuko Kitagawa
Pancreatic ductal adenocarcinoma (PDAC) continues to have the poorest prognosis of all gastrointestinal malignancies, even after the tumor has been completely resected. However, only a proportion of patients achieve 5-year survival after resection. The factors predictive of achieving 5-year survival remain unclear. The aim of this study was to investigate the pre- and postoperative clinicopathological characteristics of PDAC patients with a >5-year survival after curative resection. We retrospectively reviewed patients who underwent pancreatectomy for PDAC between January 1995 and December 2011...
September 18, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28923700/venous-thromboembolism-risk-in-patients-with-locoregional-urothelial-tract-tumors
#6
Jorge D Ramos, Jonathan T Wingate, Roman Gulati, Elizabeth R Plimack, Lauren C Harshman, Thomas Powles, Simon J Crabb, Guenter Niegisch, Joaquim Bellmunt, Sylvain Ladoire, Ugo De Giorgi, Syed Hussain, Ajjai S Alva, Jack Baniel, Neeraj Agarwal, Jonathan E Rosenberg, Ulka N Vaishampayan, Matthew D Galsky, Evan Y Yu
BACKGROUND: Venous thromboembolism (VTE) is common in cancer patients, but there is limited data on patients with urothelial tract tumors (UTT). We previously identified several associative factors for increased VTE rates in patients with metastatic UTT. In this study, we assessed the frequency, associative factors, and impact on survival of VTE in patients with locoregional UTT. METHODS: Patients with locoregional bladder, upper urinary tract, or urethral cancer were included in this multi-center study from 29 academic institutions...
August 24, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28916866/laparoscopic-versus-open-parenchymal-preserving-liver-resections-in-the-posterosuperior-segments-a-case-matched-study
#7
Mathieu D'Hondt, Esther Tamby, Isabelle Boscart, Simon Turcotte, Isabelle Parmentier, Hans Pottel, Réal Lapointe, Sander Ovaere, Franky Vansteenkiste, Franck Vandenbroucke-Menu
BACKGROUND: Patients with lesions in the posterosuperior (PS) segments of the liver have been considered poor candidates for laparoscopic liver resection (LLR). This study aims to compare short-term outcomes of LLR and open liver resections (OLR) in the PS segments. METHODS: This multicenter study consisted of all patients who underwent LLR in the PS segments and all patients who underwent OLR in the PS segments between October 2011 and July 2016. Laparoscopic cases were case-matched with those who had an identical open procedure during the same period based on tumor location (same segment) and the Brisbane classification of the resection...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28905486/perioperative-allogeneic-blood-transfusion-does-not-adversely-impact-oncological-outcomes-after-radical-cystectomy-for-urinary-bladder-cancer-a-propensity-score-weighted-european-multicenter-study
#8
Malte W Vetterlein, Philipp Gild, Luis A Kluth, Thomas Seisen, Michael Gierth, Hans-Martin Fritsche, Maximilian Burger, Chris Protzel, Oliver W Hakenberg, Nicolas von Landenberg, Florian Roghmann, Joachim Noldus, Philipp Nuhn, Armin Pycha, Michael Rink, Felix K-H Chun, Matthias May, Margit Fisch, Atiqullah Aziz
OBJECTIVES: To evaluate the effect of perioperative blood transfusion (PBT) on recurrence-free survival (RFS), overall survival (OS), cancer-specific mortality (CSM), and other-cause mortality (OCM) in patients undergoing radical cystectomy (RC), utilizing a contemporary European multicenter cohort. PATIENTS AND METHODS: The PROspective MulticEnTer RadIcal Cystectomy Series (PROMETRICS) includes data on 679 patients who underwent RC at 18 European tertiary care centers in 2011...
September 14, 2017: BJU International
https://www.readbyqxmd.com/read/28902776/pancreatic-cancer-arising-from-the-remnant-pancreas-is-it-a-local-recurrence-or-new-primary-lesion
#9
Daisuke Hashimoto, Akira Chikamoto, Toshiro Masuda, Shigeki Nakagawa, Katsunori Imai, Yo-Ichi Yamashita, Howard A Reber, Hideo Baba
Local recurrence of pancreatic cancer (PC) can occur in the pancreatic remnant. In addition, new primary PC can develop in the remnant. There are limited data available regarding this so-called remnant PC. The aim of this review was to describe the characteristics and therapeutic strategy regarding remnant PC. A literature search was performed using Medline published in English according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The incidence of remnant PC has been reported to be 3% to 5%...
October 2017: Pancreas
https://www.readbyqxmd.com/read/28900997/-surgical-treatment-and-prognostic-analysis-for-57-patients-with-gastrointestinal-lymphoma
#10
Jianhong Peng, Binyi Xiao, Yixin Zhao, Cong Li, Rongxin Zhang, Gong Chen, Liren Li, Zhenhai Lu, Peirong Ding, Desen Wan, Zhizhong Pan, Xiaojun Wu
OBJECTIVE: To explore clinicopathologic characteristics, surgical features and prognostic factors in patients with primary gastrointestinal lymphoma(PGIL) in order to provide evidence for optimizing surgical treatment. METHODS: Clinicopathological data of 57 PGIL patients undergoing abdominal surgery in Sun Yat-sen University Cancer Center between October 1990 and January 2015 were retrospectively collected. The survival rates were compared among patients with different clinicopathologic characteristics by Kaplan-Meier method, while Cox regression model was employed to analyze the prognostic factors...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28891127/helicobacter-pylori-gastric-cancer-and-other-gastrointestinal-malignancies
#11
REVIEW
Marino Venerito, Riccardo Vasapolli, Theodore Rokkas, Jean-Charles Delchier, Peter Malfertheiner
In a retrospective study performed in California, U.S.A., ca. 3% of patients with gastric intestinal metaplasia (GIM) developed gastric cancer (GC) within a median time period of 4.6 years after diagnosis of GIM. This observation stresses the importance of targeted surveillance even in regions with a low GC prevalence. Patients with alcoholic liver disease as well as survivors of colorectal and lobular breast cancer were found to be at increased risk of secondary GC. A population-based Chinese study confirmed "serologic biopsy" as a useful screening tool for stratifying the individual risk of developing GC...
September 2017: Helicobacter
https://www.readbyqxmd.com/read/28890825/splenectomy-is-an-independent-risk-factor-for-poorer-perioperative-outcomes-after-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-an-analysis-of-936-procedures
#12
Akshat Saxena, Winston Liauw, David L Morris
BACKGROUND: There is a paucity of data on the impact of splenectomy on peri-operative outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). We report the largest series to date which addresses this topic. METHODS: Nine hundred and thirty six consecutive patients underwent CRS/HIPEC from 1996 to 2016 at a high-volume institution in Sydney, Australia. Of these, 418 (45%) underwent splenectomy. Peri-operative complications were graded according to the Clavien-Dindo Classification...
August 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28889727/multidisciplinary-treatment-of-colorectal-liver-metastases
#13
Tobias S Schiergens, Jobst von Einem, Michael N Thomas, Markus Albertsmeier, Clemens Giessen-Jung, Maximilian Dörsch, Christian Heiliger, Moritz Drefs, Joachim Andrassy, Dominik P Modest, Sebastian Stintzing, Markus Guba, Martin Angele, Jens Werner, Markus Rentsch
INTRODUCTION: The therapy of patients with colorectal liver metastases (CRLM) has undergone significant changes. Extended survival has been observed to be associated with adoption of hepatic resection and improved chemotherapy. EVIDENCE ACQUISITION: This review summarizes standards, developments and controversies on the management of these patients. Literature search was performed with focus on work published within the last ten years. EVIDENCE SYNTHESIS: Patients with CRLM should undergo surgery whenever possible with careful and experienced patient selection as hepatic resection offers the best long-term prognosis...
September 8, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28888800/percutaneous-lung-ablation-of-pulmonary-recurrence-may-improve-survival-in-selected-patients-undergoing-cytoreductive-surgery-for-colorectal-cancer-with-peritoneal-carcinomatosis
#14
T A Bin Traiki, O M Fisher, S J Valle, R N Parikh, M A Kozman, D Glenn, M Power, W Liauw, N A Alzahrani, D L Morris
PURPOSE: To analyze the outcomes of patients developing pulmonary metastases (PM) following cytoreductive surgery (CRS) and perioperative intra-peritoneal chemotherapy (IPC) for colorectal cancer (CRC) with peritoneal carcinomatosis. PATIENTS AND METHODS: A retrospective analysis of patients undergoing CRS/IPC for CRC from 1996 to 2016 was performed. Lung-specific disease-free and patient overall survival was analyzed. Patients undergoing percutaneous lung ablative therapy (PLAT) for PM were compared to patients receiving systemic chemotherapy alone...
August 31, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28884391/prognostic-significance-of-surgical-margin-size-after-neoadjuvant-folfox-and-or-folfiri-for-colorectal-liver-metastases
#15
Cynthia L Miller, Martin S Taylor, Motaz Qadan, Vikram Deshpande, Steven Worthington, Robert Smalley, Chey Collura, David P Ryan, Jill N Allen, Lawrence S Blaszkowsky, Jeffrey W Clark, Janet E Murphy, Aparna R Parikh, David Berger, Kenneth K Tanabe, Keith D Lillemoe, Cristina R Ferrone
PURPOSE: Optimal margin size when resecting colorectal liver metastases (CRLM) remains unclear, particularly in the setting of perioperative chemotherapy. We evaluated the prognostic significance of margin size in patients who received neoadjuvant FOLFOX and/or FOLFIRI prior to resection of CRLM. METHODS: Clinicopathologic factors were collected for patients who underwent curative liver resections for CRLM between 4/2004-1/2016 and received neoadjuvant oxaliplatin and/or irinotecan and 5-FU (FOLFOX, FOLFIRI)...
September 7, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28878595/neoadjuvant-platinum-based-chemotherapy-is-an-independent-predictor-for-preoperative-thromboembolic-events-in-bladder-cancer-patients-undergoing-radical-cystectomy
#16
Cliodhna Browne, Niall F Davis, William J Nolan, Eoin D MacCraith, Gerald M Lennon, David W Mulvin, David J Galvin, David M Quinlan
INTRODUCTION: Neoadjuvant chemotherapy (NAC) confers a significant survival benefit in patients with muscle invasive bladder cancer. Platinum-based chemotherapy increases the risk of thromboembolic events (TEE). We determined the effect of cisplatin-based NAC on the incidence of preoperative TEEs in radical cystectomy patients. MATERIALS AND METHODS: A retrospective matched case-control study was performed on 55 patients undergoing radical cystectomy for muscle invasive bladder cancer...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28877045/advances-in-the-treatment-of-gastric-cancer
#17
David H Ilson
PURPOSE OF REVIEW: To review recent studies in esophagogastric cancer. RECENT FINDINGS: Positive emission tomography (PET) scan in follow-up after curative treatment of esophagogastric cancer did not lead to improved survival. In the preoperative treatment of esophagogastric cancer, the addition of the antivascular endothelial growth factor agent bevacizumab to perioperative chemotherapy with combination epirubicin, cisplatinum, and 5-fluorouracil (5-FU; ECF) failed to improve survival compared with chemotherapy alone...
September 4, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28872778/effects-of-thiazolidinedione-in-patients-with-active-bladder-cancer
#18
Roger Li, Michael J Metcalfe, J E Ferguson Rd, Sharada Mokkapati, Graciela M Nogueras González, Colin P Dinney, Neema Navai, David J McConkey, Sunil K Sahai, Ashish M Kamat
OBJECTIVE: To examine the influence of perioperative thiazolidinedione (TZD) on cancer-specific outcomes in patients undergoing radical cystectomy (RC) for urothelial carcinoma (UC). DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort of 173 diabetic patients undergoing RC from 2005 to 2010 was identified. Of those, 53 were on TZD treatment at the time of surgery, with 33 patients taking pioglitazone. Baseline clincopathologic characteristics, as well as cancer specific survival (CSS), recurrence free survival (RFS), and overall survival (OS) were compared between the patients on and off of TZD at the time of RC...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28871569/treatment-strategies-and-outcome-of-surgery-for-synchronous-colorectal-liver-metastases
#19
Daniel Reding, Bernhard Cornelius Pestalozzi, Stefan Breitenstein, Roger Stupp, Pierre-Alain Clavien, Ksenija Slankamenac, Panagiotis Samaras
OBJECTIVES: To report survival following different operative strategies and perioperative chemotherapy in patients with synchronous colorectal liver metastases in a tertiary academic referral centre. METHODS: We performed a retrospective analysis, based on a prospective database, of patients who presented with synchronous colorectal liver metastases. Follow-up data were obtained from medical records, letters or telephone contacts. The main endpoint was overall survival...
September 5, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28866245/incidence-and-effect-of-thromboembolic-events-in-radical-cystectomy-patients-undergoing-preoperative-chemotherapy-for-muscle-invasive-bladder-cancer
#20
Aditya Bagrodia, Ranjit Sukhu, Andrew G Winer, Eric Levy, Michael Vacchio, Byron Lee, Eugene J Pietzak, Timothy F Donahue, Eugene Cha, Gopa Iyer, Daniel D Sjoberg, Andrew J Vickers, Jonathan E Rosenberg, Dean F Bajorin, Guido Dalbagni, Bernard H Bochner
BACKGROUND: We evaluated the incidence and effect of thromboembolic events (TEEs) in patients with muscle-invasive bladder cancer treated with preoperative chemotherapy (POC) and radical cystectomy (RC) with pelvic lymph node dissection (PLND). PATIENTS AND METHODS: We performed a retrospective review of all patients who had undergone POC followed by RC plus PLND for muscle-invasive bladder cancer from June 2000 to January 2013 (n = 357). The chemotherapy type (neoadjuvant vs...
August 10, 2017: Clinical Genitourinary Cancer
keyword
keyword
32529
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"