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baseline testing

Walquiria Batista Andrade, Jeferson Lucas Jacinto, Douglas Kratki da Silva, Mirela Casonato Roveratti, José Maria Estoche, Douglas Benedito Oliveira, Mario Carlos Welin Balvedi, Rubens A da Silva, Andreo Fernando Aguiar
The purpose of this study was to investigate the effects of L-arginine (L-arg) supplementation on muscle recovery process after a single session of high-intensity resistance exercise (RE). 20 healthy young adult (22.8 ± 3.4 y) participants were assigned to two groups (N = 10/group): a placebo-supplement group (PLA) or a L-arginine-supplement group (ARG). The groups completed a session of high-intensity RE (0h), and three subsequent fatigue tests sessions (at 24, 48 and 72 h post-exercise) to assess the time course of muscle recovery...
March 15, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Taner Arabaci, Mevlut Albayrak
BACKGROUND: The aim of this study to evaluate the contributions of titanium-prepared platelet-rich fibrin (T-PRF) combined with open flap debridement (OFD) on biological markers in gingival crevicular fluid (GCF)and periodontal outcomes. METHODS: Twenty-nine participants with chronic periodontitis were treated either with autologous T-PRF+OFD or OFD alone. GCF growth factor levels and relative receptor activator nuclear factor kappa-B/osteoprotegerin (RANKL/OPG) ratio at baseline and 2, 4, and 6 weeks postoperatively were analyzed, and clinical parameters such as probing depth (PD), relative attachment level (RAL) and gingival margin level (GML) at baseline and 9 months after surgery were compared...
March 2018: Journal of Periodontology
Christian Møller Madsen, Benjamin Badault, Lars Nybo
Badminton-specific speed and endurance performance was evaluated in both cross-sectional and longitudinal studies of elite youth players and compared to the physiological capacities of world top-50 singles players.The cross-sectional study involved ten males in the category U15 (<15 years), ten U17, nine U19 and four senior elite players. They performed 30-m sprint, counter-movement jump (CMJ) and badminton-specific speed (B-SPEED) and endurance (B-ENDURANCE) tests. The longitudinal data were collected for ten U15 players with 1- and 2-year follow-up measures...
March 13, 2018: Journal of Strength and Conditioning Research
Mario Silva, Cornelia M Schaefer-Prokop, Colin Jacobs, Giovanni Capretti, Francesco Ciompi, Bram van Ginneken, Ugo Pastorino, Nicola Sverzellati
OBJECTIVES: The aim of this study was to compare computer-aided diagnosis (CAD) and visual reading for the detection of subsolid nodules (SSNs) in volumetrl measuremic low-dose computed tomography (LDCT) for lung cancer screening. MATERIALS AND METHODS: Prospective visual detection (VD) and manuaent of SSN were performed in the 2303 baseline volumetric LDCTs of the Multicenter Italian Lung Detection trial. Baseline and 2- and 4-year LDCTs underwent retrospective CAD analysis, subsequently reviewed by 2 experienced thoracic radiologists...
March 14, 2018: Investigative Radiology
Young Joon Choi, Si Yoon Park, Ikhyun Jun, Moonjung Choi, Kyoung Yul Seo, Eung Kweon Kim, Tae-Im Kim
PURPOSE: To evaluate perioperative dry eye (DE) syndrome and meibomian gland dysfunction (MGD) parameters associated with persistent DE symptoms after cataract surgery. METHODS: We enrolled patients who underwent uncomplicated cataract surgery without previous ocular comorbidities and previous use of ophthalmic treatment except for artificial tears at a single tertiary hospital. Lipid layer thickness, meibomian gland (MG) dropout, tear breakup time, Oxford staining score, lid margin abnormality, meibum quality, meibum expressibility, MG orifice obstruction, MGD stage, Ocular Surface Disease Index (OSDI), and Schirmer test score were prospectively assessed in order at baseline and 1 and 3 months postoperative...
March 14, 2018: Cornea
I A Filatova
By improving the existing surgical technologies for dacryocystitis, one enhances the effectiveness of patient rehabilitation. AIM: To evaluate the effectiveness of radio-wave surgery in the treatment of dacryocystitis and lacrimal sac abscesses. MATERIAL AND METHODS: The clinical group consisted of 207 patients ranging in age from 7 to 89 years (the mean age of 41±7.3 years). For 39% of patients this was a repeated treatment, while 9.3% had undergone 4-5 surgical interventions...
2018: Vestnik Oftalmologii
Christopher P Tomczyk, Megan Mormile, Megan S Wittenberg, Jody L Langdon, Tamerah N Hunt
CONTEXT:   An estimated 15.3 million adolescent students are enrolled in U.S. high schools, with approximately 7.8 million participating in athletics. Researchers have examined various demographics in high school athletes; however, athletic participation may play a larger role in test performance than previously thought. Currently, investigations of concussion assessment may rely on uninjured athletes as controls. However, due to the intense nature of athletics, this may not be an appropriate practice...
March 15, 2018: Journal of Athletic Training
Sylvie Perreault, Payman Shahabi, Robert Côté, Stéphanie Dumas, Étienne Rouleau-Mailloux, Yassamin Feroz Zada, Sylvie Provost, Ian Mongrain, Marc Dorais, Thao Huynh, Simon Kouz, Ariel Diaz, Mark Blostein, Simon de Denus, Jacques Turgeon, Jeffrey Ginsberg, Jacques Lelorier, Lyne Lalonde, Lambert Busque, Jeannine Kassis, Mario Talajic, Jean-Claude Tardif, Marie-Pierre Dubé
BACKGROUND: Over- and under-coagulation with warfarin is associated with hemorrhagic and thromboembolic events, respectively. Genetic and clinical factors affect warfarin response, and the causes of this variability remain unclear. We present descriptive statistics and test for predictors of poor anticoagulation control. METHODS: The Quebec Warfarin Cohort (QWC) comprises 1,059 new warfarin users, with prospective follow up using telephone questionnaires every 3 months for one year, and using healthcare administrative databases (RAMQ and Med-Echo) for 5-year prior to cohort entry and up to 10-years following active patient participation...
March 15, 2018: Clinical Cardiology
Giovanni Castellini, Lorenzo Lelli, Emanuele Cassioli, Eleonora Ciampi, Francesco Zamponi, Beatrice Campone, Alessio Maria Monteleone, Valdo Ricca
The aim of this study was to evaluate the role of childhood adversities in long-term outcomes in eating disorders (EDs). One hundred thirty-three eating disorder patients were studied by means of the Structured Clinical Interview for DSM-IV and psychometric tests, at baseline, at the end of individual cognitive behavioural therapy, and at 3-year follow-up. As compared with the other patients, those reporting childhood abuse (overall: 24.8%; physical abuse: 20.3%; sexual abuse: 13.6%) showed higher impulsivity, psychiatric comorbidity, lower full recovery at follow-up (12...
March 15, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
Lauren Massimo, Sharon X Xie, Lior Rennert, Donna M Fick, Amy Halpin, Katerina Placek, Andrew Williams, Katya Rascovsky, David J Irwin, Murray Grossman, Corey T McMillan
To evaluate whether occupational attainment influences the trajectory of longitudinal cognitive decline in behavioral variant frontotemporal degeneration (bvFTD). Single-center, retrospective, longitudinal study. Sixty-three patients meeting consensus criteria for bvFTD underwent evaluation at the University of Pennsylvania Frontotemporal Degeneration Center. All patients were studied longitudinally on letter-guided fluency, category-naming fluency and Boston Naming Test (BNT). Occupational attainment was defined categorically by assigning each individual's occupation to a professional or non-professional category...
March 14, 2018: Brain Imaging and Behavior
W Weinrebe, S Käbe-Frisch, I Füsgen, M Karaman, E Johannsdottir, S Rupp
OBJECTIVE: To compare the efficacy of desmopressin and placebo in independent geriatric outpatients with nocturnal polyuria (NP). METHODS: A prospective, randomized, single-center, national, double blind, placebo-controlled, fixed-dose, parallel group comparative trial was carried out. The study included 110 geriatric outpatients, 55 patients per treatment group using desmopressin acetate nasal spray (strength: 0.1 mg/ml) once daily of 10 μg/spray blast or placebo...
March 14, 2018: Zeitschrift Für Gerontologie und Geriatrie
Nicole Stone, Cynthia Graham, Sydney Anstee, Katherine Brown, Katie Newby, Roger Ingham
Background: Condoms remain the main protection against sexually transmitted infections (STIs) when used correctly and consistently. Yet, there are many reported barriers to their use such as negative attitudes, reduced sexual pleasure, fit-and-feel problems and erection difficulties. The UK home-based intervention strategy (HIS-UK) is a behaviour change condom promotion intervention for use among young men (aged 16-25 years) designed to increase condom use by enhancing enjoyment of condom-protected intercourse...
2018: Pilot and Feasibility Studies
Swee Siang Wong, Cheng Hua Huang, Chiu Chu Yang, Yi Pei Hsieh, Chen Ni Kuo, Yi Ru Chen, Li Ching Chen
Background: Environmental cleaning is a fundamental principle of infection control in health care settings. We determined whether implementing separated environmental cleaning management measures in MICU reduced the density of HAI. Methods: We performed a 4-month prospective cohort intervention study between August and December 2013, at the MICU of Cathay General hospital. We arranged a training program for all the cleaning staff regarding separated environmental cleaning management measures by using disposable wipes of four colors to clean the patients' bedside areas, areas at a high risk of contamination, paperwork areas, and public areas...
2018: Antimicrobial Resistance and Infection Control
Philip W Cameron, Noelle C Soltero, Justin Byers
Mild traumatic brain injuries (mTBIs) are common in contact sports. There is an association between mTBIs and altered motor function. BioSway technology measures individuals' balance using the Balance Error Scoring System (BESS). Prior to incorporating BESS testing in concussion protocol, other variables that influence the BESS test require review. The objective of this study is to determine if game fatigue in hockey players also influences the BESS score. 23 male (21.08 ± 1.09) National Collegiate Athletic Association (NCAA) athletes were tested using the BioSway™ (Biodex, USA)...
2018: International Journal of Exercise Science
Boe M Burrus, Brian M Moscicki, Tracey D Matthews, Vincent J Paolone
Chronic supplementation of L-carnitine and carbohydrate has been reported to increase L-carnitine content in skeletal muscle and have positive influences on exercise variables and performance. This study investigated the acute intake of L-carnitine and carbohydrate on the exercise parameters of cycling. A total of 10 males (27.0 ± 4 years) completed two exercise sessions consisting of 40 min of cycling at 65% of VO2peak , followed by cycling to exhaustion at 85% of VO2peak . L-carnitine or a placebo was consumed 3 hours prior to exercise, and beverages consisting of 94 g of carbohydrate were consumed at both 2 hours, and 30 minutes prior to exercise...
2018: International Journal of Exercise Science
G Vittoria, G Pantaleo, A Blasi, G Spagnuolo, A Iandolo, M Amato
Background: There are a lot of techniques to obturate the root canals, but lateral condensation of gutta-percha is the most used one. An important aspect of thermafil is the error margin tolerated by the manufacturer in the production of plastic carriers. In literature, there is no evidence about discrepancy percentage between different carriers. It is demonstrated that the error margin of gutta-percha is 0.5% and is 0.2% for metal files (ISO standards). Objective: The aim of this study was to evaluate the real dimensions of thermafil plastic carriers observed by the stereo microscope measuring the dimensional discrepancy between them...
2018: Open Dentistry Journal
Kristina Jakob, Hanna Ehrentreich, Sarah K C Holtfrerich, Luise Reimers, Esther K Diekhof
Hormone by genotype interactions have been widely ignored by cognitive neuroscience. Yet, the dependence of cognitive performance on both baseline dopamine (DA) and current 17ß-estradiol (E2) level argues for their combined effect also in the context of reinforcement learning. Here, we assessed how the interaction between the natural rise of E2 in the late follicular phase (FP) and the 40 base-pair variable number tandem repeat polymorphism of the dopamine transporter (DAT1) affects reinforcement learning capacity...
2018: Frontiers in Endocrinology
Orrin Devinsky, Anup D Patel, Elizabeth A Thiele, Matthew H Wong, Richard Appleton, Cynthia L Harden, Sam Greenwood, Gilmour Morrison, Kenneth Sommerville
OBJECTIVE: To evaluate the safety and preliminary pharmacokinetics of a pharmaceutical formulation of purified cannabidiol (CBD) in children with Dravet syndrome. METHODS: Patients aged 4-10 years were randomized 4:1 to CBD (5, 10, or 20 mg/kg/d) or placebo taken twice daily. The double-blind trial comprised 4-week baseline, 3-week treatment (including titration), 10-day taper, and 4-week follow-up periods. Completers could continue in an open-label extension. Multiple pharmacokinetic blood samples were taken on the first day of dosing and at end of treatment for measurement of CBD, its metabolites 6-OH-CBD, 7-OH-CBD, and 7-COOH-CBD, and antiepileptic drugs (AEDs; clobazam and metabolite N -desmethylclobazam [N-CLB], valproate, levetiracetam, topiramate, and stiripentol)...
March 14, 2018: Neurology
Mark R Hazebroek, Ingrid Krapels, Job Verdonschot, Arthur van den Wijngaard, Els Vanhoutte, Marije Hoos, Luc Snijders, Lieke van Montfort, Maryvonne Witjens, Robert Dennert, Harry J G M Crijns, Hans-Peter Brunner-La Rocca, Han G Brunner, Stephane Heymans
BACKGROUND: Genetic evaluation is recommended in patients with unexplained dilated cardiomyopathy (DCM), but its diagnostic yield and prognostic relevance in unexplained isolated left ventricular dysfunction (LVdys) is unknown. METHODS AND RESULTS: A total of 127 LVdys and 262 DCM patients underwent genetic screening. Long-term outcome consisted of a combined end point of life-threatening arrhythmia, heart transplantation, and death. At baseline, LVdys patients were younger and had less frequently New York Heart Association class ≥3 when compared with DCM (55±13 versus 58±12; P =0...
March 2018: Circulation. Heart Failure
Frédéric N Brière, Gabrielle Yale-Soulière, Daniela Gonzalez-Sicilia, Marie-Josée Harbec, Julien Morizot, Michel Janosz, Linda S Pagani
BACKGROUND: Engaging in sport has been suggested to be mitigate against psychological distress. Using a prospective-longitudinal design, we examine whether sport participation is associated with reduced psychological difficulties in adolescents and whether associations differ by sport and personal characteristics. METHODS: 17 550 adolescents from grade 7 to 10 (mean age=14.4 years old) self-reported on sport participation, depressive symptoms, social anxiety symptoms and loneliness in Spring 2007 and 1 year later...
March 14, 2018: Journal of Epidemiology and Community Health
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