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https://www.readbyqxmd.com/read/29791875/effects-of-potassium-application-on-potato-starch-physicochemical-properties
#1
Wei Zhang, Xinwei Liu, Qiaolan Wang, Haiqing Zhang, Mingfeng Li, Botao Song, Zhuqing Zhao
Potato starch serves as an excellent raw material or food additive in the food industry. With the advancement of the potato staple food strategy in China, improving the potato starch yield and quality has attracted more and more attention. Potassium is an essential nutrient for potato due to its direct effects on the yield and quality of potato tubers. Here, the effects of three different potassium levels on potato starch physicochemical properties were evaluated by field experiments. With increasing potassium application rates, the amylose content, phosphorus content and particle size decreased, thereby resulting in low gelatinization temperature, breakdown and setback viscosity, and high swelling power, relative crystallinity and transparency...
May 20, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29788966/dyslipidemia-prevalence-awareness-treatment-control-and-risk-factors-in-chinese-rural-population-the-henan-rural-cohort-study
#2
Xiaotian Liu, Songcheng Yu, Zhenxing Mao, Yuqian Li, Haiqing Zhang, Kaili Yang, Honglei Zhang, Ruihua Liu, Xinling Qian, Linlin Li, Ronghai Bie, Chongjian Wang
BACKGROUND: The prevalence of dyslipidemia continue to increase in recent decades in China, however, little is known about the recent prevalence, awareness, treatment, control, and potential risk factors of dyslipidemia in the rural areas of China. METHODS: A total of 39,207 participants aged 18-79 years were recruited for the epidemiological research from the Henan Rural Cohort study. The age- and sex-adjusted means (95% confidence intervals, CI) of serum lipid levels or percentages of prevalence, awareness, treatment, and control overall and in various population subgroups were estimated and compared by multiple linear regression or logistic regression...
May 22, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29765319/progression-and-regression-of-hepatic-lesions-in-a-mouse-model-of-nash-induced-by-dietary-intervention-and-its-implications-in-pharmacotherapy
#3
Zhi-Ming Ding, Yue Xiao, Xikun Wu, Haixia Zou, Shurong Yang, Yiyun Shen, Juehua Xu, Heather C Workman, Amy L Usborne, Haiqing Hua
Understanding of the temporal changes of hepatic lesions in the progression and regression of non-alcoholic steatohepatitis (NASH) is vital to elucidation of the pathogenesis of NASH, and critical to the development of a strategy for NASH pharmacotherapy. There are challenges in studying hepatic lesion progression and regression in NASH patients due to the slow development of NASH in humans, one being the requirement for multiple biopsies during the longitudinal follow-up. Here we studied lesion progression and regression in the diet-induced animal model of NASH by application or removal of the pathogenic diet for multiple time periods...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29763448/modulation-of-functional-activity-and-connectivity-by-acupuncture-in-patients-with-alzheimer-disease-as-measured-by-resting-state-fmri
#4
Weimin Zheng, Zhuangzhi Su, Xingyun Liu, Hao Zhang, Ying Han, Haiqing Song, Jie Lu, Kuncheng Li, Zhiqun Wang
Acupuncture has been used in the therapy of Alzheimer disease (AD); however, its neural mechanisms are still unclear. The aim of this study is to examine the effect of acupuncture on the functional connectivity in AD by using resting-state functional magnetic resonance imaging (rs-fMRI). Twenty-eight subjects (14 AD and 14 normal controls) participated in this study. The rs-fMRI data were acquired before and after acupuncture stimulation at the acupoints of Tai chong (Liv3) and Hegu (LI4). During the baseline resting state, by using the amplitude of low-frequency fluctuations (ALFF), we found a significantly decreased or increased ALFF in the AD patients relative to the controls...
2018: PloS One
https://www.readbyqxmd.com/read/29752834/h-2-o-2-induces-pp2a-demethylation-to-downregulate-mtorc1-signaling-in-hek293-cells
#5
Shen Tang, Fu Qin, Xinhang Wang, Ziwei Liang, Haiqing Cai, Laiming Mo, Yue Huang, Boyin Liang, Xuejing Wei, Qingqing Ao, Yilu Xu, Yuyang Liu, Deqiang Xiao, Songchao Guo, Cailing Lu, Xiyi Li
Mammalian target of rapamycin (mTOR) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to govern cell growth and proliferation by mediating mitogen- and nutrient-dependent signal transduction. Protein phosphatase 2A (PP2A), a ubiquitously expressed serine/threonine phosphatase, negatively regulates mTOR signaling. Methylation of PP2A is catalyzed by leucine carboxyl methyltransferase-1 (LCMT1) and reversed by protein phosphatase methylesterase 1 (PME-1), which regulates PP2A activity and substrate specificity...
May 12, 2018: Cell Biology International
https://www.readbyqxmd.com/read/29749961/superconductivity-in-solid-benzene-molecular-crystal
#6
Guo-Hua Zhong, Chun-Lei Yang, Xiaojia Chen, Haiqing Lin
Light-element compounds hold great promise of high critical temperature superconductivity judging from the theoretical perspective. Hydrogen-rich material, benzene, is such a kind of candidate but also an organic compound. A series of first-principles calculations are performed on the electronic structures, dynamics properties, and electron-phonon interactions of solid benzene at high pressures. Benzene is found to be dynamically stable in the pressure range of 180-200 GPa and to exhibit superconductivity with a maximum transition temperature of 20 K at 195 GPa...
May 11, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29739895/long-term-survival-rates-of-patients-with-stage-iii-iv-hodgkin-lymphoma-according-to-age-sex-race-and-socioeconomic-status-1984-2013
#7
Yushi Li, Huanhuan Sun, Yan Yan, Tiantian Sun, Shuncong Wang, Haiqing Ma
BACKGROUND: Long-term survival rates for patients with stage III-IV Hodgkin lymphoma, or advanced Hodgkin lymphoma (aHL), have increased substantially since the 1960s. Because large-scale research of aHL is rare, we aimed to demonstrate the differences in incidence and survival of aHL according to four patient variables in recent decades, with a focus on the outcomes of treatment of aHL and the advancement of public health care. MATERIALS AND METHODS: Data on aHL cases diagnosed during 1984-2013 were extracted from the Surveillance, Epidemiology, and End Results Program database...
May 8, 2018: Oncologist
https://www.readbyqxmd.com/read/29738511/manufacturing-a-long-period-grating-with-periodic-thermal-diffusion-technology-on-high-na-fiber-and-its-application-as-a-high-temperature-sensor
#8
Xiang Shen, Bin Dai, Yingbin Xing, Luyun Yang, Haiqing Li, Jinyan Li, Jingang Peng
We demonstrated a kind of long-period fiber grating (LPFG), which is manufactured with a thermal diffusion treatment. The LPFG was inscribed on an ultrahigh-numerical-aperture (UHNA) fiber, highly doped with Ge and P, which was able to easily diffuse at high temperatures within a few seconds. We analyzed how the elements diffused at a high temperature over 1300 °C in the UHNA fiber. Then we developed a periodically heated technology with a CO₂ laser, which was able to cause the diffusion of the elements to constitute the modulations of an LPFG...
May 8, 2018: Sensors
https://www.readbyqxmd.com/read/29717155/survey-of-antithrombotic-treatment-in-rural-patients-60-years-with-atrial-fibrillation-in-east-china
#9
Yong Wei, Juan Xu, Haiqing Wu, Genqing Zhou, Songwen Chen, Caihong Wang, Yahong Shen, Shunhong Yang, Bin Wang, Zheng He, Jianping Sun, Weidong Sun, Ping Ouyang, Shaowen Liu
The prevalence and antithrombotic treatment of atrial fibrillation (AF) in Chinese rural population is not well known. The aim of this study was to investigate the extent to which antithrombotic treatment was prescribed for rural AF patients >60 years. We identified 828 AF patients from 36734 rural residents >60 years in Shanghai China. Our data indicated the overall prevalence rate of AF was 2.3% in rural population >60 years in East China and 38.9% of AF patients underwent antithrombotic therapy, including warfarin (5...
May 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29714312/confined-doped-fiber-for-effective-mode-control-fabricated-by-mcvd-process
#10
Lei Liao, Fangfang Zhang, Xinglong He, Yisha Chen, Yibo Wang, Haiqing Li, Jinggang Peng, Luyun Yang, Nengli Dai, Jinyan Li
A confined-doped fiber was fabricated by a modified chemical vapor deposition (MCVD) process based on refractive index matching technology. With theory and experiments, we compared the confined-doped fiber and normal-doped fiber. We found that the confined-doped fiber with a core of 35 μm and 0.07 numerical aperture could achieve single-mode output and improve the beam quality from 2.8 to 1.5 in the fiber laser. Meanwhile, it still possesses high laser efficiency and has good stability of beam quality with the increase in pump power...
April 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29712658/determination-of-mic-distribution-and-mechanisms-of-decreased-susceptibility-to-bedaquiline-among-clinical-isolates-of-mycobacterium-abscessus
#11
Bing Li, Meiping Ye, Qi Guo, Zhemin Zhang, Shiyi Yang, Wei Ma, Fangyou Yu, Haiqing Chu
Chemotherapeutic options are very limited against Mycobacterium abscessus infections. Bedaquiline, a new anti-tuberculosis drug, is effective for the treatment of multidrug-resistant TB. However, little data is available on bedaquiline in treating M. abscessus infections. In this study, we reported the in vitro susceptibility profile of M. abscessus clinical isolates to bedaquiline and investigated the potential molecular mechanisms of decreased susceptibility. A total of 197 M. abscessus clinical isolates were collected from sputum and bronchoalveolar fluid of patients with lung infections...
April 30, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29709288/is-the-bishop-koop-procedure-useful-in-severe-jejunoileal-atresia
#12
Yanfen Peng, Haiqing Zheng, Qiuming He, Zhe Wang, Hong Zhang, Puja Bk Chaudhari, Wei Zhong, Jiakang Yu
PURPOSE: The aim of this study was to report our experience using the Bishop-Koop procedure for the treatment of various surgical problems of jejunoileal atresia including luminal discrepancy, complex meconium peritonitis, type IIIb and type IV atresia which we defined as severe jejunoileal atresia. METHODS: This retrospective study was performed on the patients with severe jejunoileal atresia who underwent Bishop-Koop procedure at a tertiary center in China over a five year of period...
April 5, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29707573/impact-of-health-education-on-knowledge-and-behaviors-toward-infectious-diseases-among-students-in-gansu-province-china
#13
Manli Wang, Xuemei Han, Haiqing Fang, Chang Xu, Xiaojun Lin, Shuxu Xia, Wenhan Yu, Jinlu He, Shuai Jiang, Hongbing Tao
Objectives: Infectious disease knowledge and behaviors are key elements that ensure student health and safety. This study explores the impact of health education on student knowledge and behaviors toward infectious diseases and determines the factors affecting infectious diseases knowledge and behaviors among students in Gansu, China. Methods: A cross-sectional study and three sampling methods were used in two counties, 12 schools, and 32 classes in Gansu, China, from 2012 to 2013...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29695961/altered-functional-connectivity-of-insular-subregions-in-alzheimer-s-disease
#14
Xingyun Liu, Xiaodan Chen, Weimin Zheng, Mingrui Xia, Ying Han, Haiqing Song, Kuncheng Li, Yong He, Zhiqun Wang
Recent researches have demonstrated that the insula is the crucial hub of the human brain networks and most vulnerable region of Alzheimer's disease (AD). However, little is known about the changes of functional connectivity of insular subregions in the AD patients. In this study, we collected resting-state functional magnetic resonance imaging (fMRI) data including 32 AD patients and 38 healthy controls (HCs). By defining three subregions of insula, we mapped whole-brain resting-state functional connectivity (RSFC) and identified several distinct RSFC patterns of the insular subregions: For positive connectivity, three cognitive-related RSFC patterns were identified within insula that suggest anterior-to-posterior functional subdivisions: (1) an dorsal anterior zone of the insula that exhibits RSFC with executive control network (ECN); (2) a ventral anterior zone of insula, exhibits functional connectivity with the salience network (SN); (3) a posterior zone along the insula exhibits functional connectivity with the sensorimotor network (SMN)...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29694791/genetic-variant-q63r-of-cannabinoid-receptor-2-cb2r-causes-differential-erk-phosphorylation-in-human-immune-cells
#15
Jingru Wang, Juehua Xu, Jie Liu, Huang Zhu, Yanyan Peng, Zhi-Ming Ding, Haiqing Hua
BACKGROUND: The cannabinoid receptor 2 (CB2R) is primarily expressed in immune tissues and implicated in immune regulation. In models of inflammatory diseases, modulation of CB2R alters function of immune cells and affects the progression of disease. We therefore believe that CB2R modulation could be a promising therapy for inflammatory diseases. In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases...
April 25, 2018: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/29693177/the-therapeutic-effect-of-artesunate-on-rosacea-through-the-inhibition-of-the-jak-stat-signaling-pathway
#16
Ting Li, Qingwen Zeng, Xingming Chen, Guojiang Wang, Haiqing Zhang, Aihua Yu, Hairui Wang, Yang Hu
Acne rosacea is a type of chronic dermatosis with the characteristics of erubescence, angiotelectasis and pustule formation. However, current treatment methods are limited due to the side effects. Artesunate demonstrated a promising therapeutic efficacy with a high safety margin. HaCaT cells were treated with antibacterial peptide LL‑37 to simulate rosacea caused by Demodex folliculorum (D. folliculorum) infection. Cell Counting kit 8 and flow cytometry assays were performed to measure cellular proliferation, apoptosis, the stage of the cell cycle and reactive oxygen species generation in order to determine the level of cell damage...
April 16, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29680417/gender-specific-independent-and-combined-dose-response-association-of-napping-and-night-sleep-duration-with-type-2-diabetes-mellitus-in-rural-chinese-adults-the-ruraldiab-study
#17
Ruihua Liu, Yuqian Li, Zhenxing Mao, Xiaotian Liu, Haiqing Zhang, Kaili Yang, Honglei Zhang, Runqi Tu, Xinling Qian, Jingjing Jiang, Ronghai Bie, Chongjian Wang
OBJECTIVE: The aim of this study was to explore the independent and combined dose-response association of napping and night sleep duration with type 2 diabetes mellitus (T2DM) among different genders in the rural Chinese population. METHODS: For this research, a total of 19,257 participants were enrolled in the Rural Diabetes, Obesity and Lifestyle (RuralDiab) study. Napping and night sleep duration were assessed using the Pittsburgh Sleep Quality Index (PSQI). Restricted cubic splines and logistic regression were used to estimate the relationship between napping and night sleep duration with T2DM...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29678775/involvement-of-gap-junctions-in-astrocyte-impairment-induced-by-manganese-exposure
#18
Cailing Lu, Zhijuan Meng, Yiyuan He, Deqiang Xiao, Haiqing Cai, Yilu Xu, Xianghong Liu, Xinhang Wang, Laiming Mo, Ziwei Liang, Xuejing Wei, Qingqing Ao, Boying Liang, Xiyi Li, Shen Tang, Songchao Guo
Glutamate excitotoxicity, characterized as excessive glutamate stress, is considered to be involved in cerebral ischaemia, brain trauma, and neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. Glutamate homeostasis disruption was highlighted in Mn neurotoxicity caused by high levels of Mn. Astrocytes, accounting for approximately 50% of the neuronal cells in the central nervous system and maintain glutamate homeostasis, are sensitive to neurotoxicity induced by Mn exposure. Astrocytes are tightly coupled with gap junctions (GJ), which are comprised of connexins, mainly connexin43 (Cx43)...
April 17, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29670374/multiline-treatment-combining-apatinib-with-toptecan-for-platinum-resistant-recurrent-ovarian-cancer-patients-a-report-of-three-cases
#19
Yuan Cheng, Juan Zhang, Haiyun Geng, Shukui Qin, Haiqing Hua
The aim of this study was to observe the efficacy and safety of apatinib combined with toptecan therapy in the multiline treatment of platinum-resistant recurrent ovarian cancer patients. The clinical records of three patients with platinum-resistant recurrent ovarian cancer treated with apatinib combined with toptecan therapy were analyzed and followed up for 3 months, and the related literatures were reviewed. The three patients achieved partial response and the tumor marker CA125 levels decreased significantly as an outcome of the treatment...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29668606/terlipressin-in-the-treatment-of-hepatorenal-syndrome-a-systematic-review-and-meta-analysis
#20
REVIEW
Haiqing Wang, Aixiang Liu, Wentao Bo, Xielin Feng, Yong Hu
BACKGROUND: Hepatorenal syndrome is a fatal complication of advanced cirrhosis. Terlipressin is the most widely used treatment method, however, the therapy effects remain inconsonant. We aim to systematically assess the safety and efficacy of terlipressin for hepatorenal syndrome. METHODS: We conducted a systematic review and meta-analysis. Randomized controlled trials involving terlipressin for hepatorenal syndrome were included in a systematic literature search...
April 2018: Medicine (Baltimore)
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