keyword
MENU ▼
Read by QxMD icon Read
search

nomogram

keyword
https://www.readbyqxmd.com/read/28923618/impact-of-induction-therapy-on-delayed-graft-function-following-kidney-transplantation-in-mated-kidneys
#1
T Butler, N Hayde
BACKGROUND: Delayed graft function (DGF) is defined as the need for dialysis within 1 week of transplantation and occurs in 20%-50% of deceased-donor kidney transplant recipients. Although recovery from DGF often occurs within a few days, many cases may take weeks to months before the transplant function begins. The delay in function increases the complexity of recipient care, makes the diagnosis of acute rejection more difficult, prolongs length of stay, and increases hospital costs...
October 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28921890/phase-ii-study-of-dabigatran-in-children-with-venous-thrombosis-pharmacokinetics-safety-and-tolerabilty
#2
J M L Halton, M Albisetti, B Biss, L Bomgaars, M Brueckmann, S Gropper, R Harper, F Huang, M Luciani, H Maas, I Tartakovsky, L G Mitchell
BACKGROUND: The current standard-of-care treatments for pediatric venous thromboembolism (VTE) have limitations. Dabigatran etexilate (DE), a direct thrombin inhibitor, may offer an alternative therapeutic option. OBJECTIVES: To assess the pharmacokinetics (PK), pharmacodynamics (PD), safety and tolerability of DE oral liquid formulation (OLF) in pediatric patients with VTE. PATIENTS/METHODS: Patients who had completed planned treatment with low-molecular-weight heparin or oral anticoagulants for VTE were enrolled in two age groups (2-<12 and 1-<2 years) and received DE OLF based on an age- and weight-adjusted nomogram...
September 16, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28919181/lymphadenectomy-in-gleason-7-prostate-cancer-adherence-to-guidelines-and-effect-on-clinical-outcomes
#3
Thenappan Chandrasekar, Hanan Goldberg, Zachary Klaassen, Rashid K Sayyid, Robert J Hamilton, Neil E Fleshner, Girish S Kulkarni
BACKGROUND: To examine usage trends, guideline adherence, and survival data for patients undergoing lymphadenectomy (LND) at the time of radical prostatectomy (RP) for Gleason 7 prostate cancer (PCa). METHODS: The SEER database was queried for all patients with nonmetastatic biopsy Gleason 7 PCa from 2004 to 2013. Distribution and trends of LND were analyzed. The Memorial-Sloan Kettering Cancer Center nomogram was applied to stratify patients based on risk of nodal disease at time of RP (<5% risk or ≥5% risk)...
September 14, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28918166/high-expression-of-cxc-chemokine-receptor-6-associates-with-poor-prognosis-in-patients-with-clear-cell-renal-cell-carcinoma
#4
Yuan Chang, Lin Zhou, Le Xu, Qiang Fu, Yuanfeng Yang, Zongming Lin, Jiejie Xu
PURPOSE: Accumulating evidence indicates that CXC chemokine receptor 6 (CXCR6) has a crucial role in cancer development and progression, however, its role in clear cell renal cell carcinoma (ccRCC) remains obscure. The aim of this study is to investigate the prognostic value of CXCR6 expression in patients with ccRCC following surgery. MATERIALS AND METHODS: This study retrospectively included 239 patients with ccRCC who underwent nephrectomy and had paraffin tissue available at a single center...
September 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28914711/change-in-eyelid-position-following-muller-s-muscle-conjunctival-resection-with-a-standard-versus-variable-resection-length
#5
Daniel B Rootman, Kunal R Sinha, Robert A Goldberg
PURPOSE: This study compares the use of a standard 7 mm resection length to a variable 4:1 ratio of resection length to desired elevation nomogram when performing Muller's muscle conjunctival resection surgery. METHODS: In this cross-sectional case control study, 2 groups were defined. The first underwent Muller's muscle conjunctival resection surgery with a standard 7 mm resection length and the second underwent the same surgery with a variable resection length determined by a 4:1 ratio of resection length to desired elevation nomogram...
September 12, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28912468/cytokine-based-predictive-models-to-estimate-the-probability-of-chronic-periodontitis-development-of-diagnostic-nomograms
#6
I Tomás, N Arias-Bujanda, M Alonso-Sampedro, M A Casares-de-Cal, C Sánchez-Sellero, D Suárez-Quintanilla, C Balsa-Castro
Although a distinct cytokine profile has been described in the gingival crevicular fluid (GCF) of patients with chronic periodontitis, there is no evidence of GCF cytokine-based predictive models being used to diagnose the disease. Our objectives were: to obtain GCF cytokine-based predictive models; and develop nomograms derived from them. A sample of 150 participants was recruited: 75 periodontally healthy controls and 75 subjects affected by chronic periodontitis. Sixteen mediators were measured in GCF using the Luminex 100™ instrument: GMCSF, IFNgamma, IL1alpha, IL1beta, IL2, IL3, IL4, IL5, IL6, IL10, IL12p40, IL12p70, IL13, IL17A, IL17F and TNFalpha...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912447/development-and-validation-of-a-nomogram-for-predicting-survival-in-patients-with-advanced-pancreatic-ductal-adenocarcinoma
#7
Qing-Long Deng, Shu Dong, Lei Wang, Chen-Yue Zhang, Hai-Feng Ying, Zhao-Shen Li, Xiao-Heng Shen, Yuan-Bao Guo, Zhi-Qiang Meng, Jin-Ming Yu, Qi-Wen Chen
This study aimed to develop and validate an effective prognostic nomogram for advanced PDAC patients. We conducted a prospective multicenter cohort study involving 1,526 advanced PDAC patients from three participating hospitals in China between January 1, 2004 and December 31, 2013. Two thirds of the patients were randomly assigned to the training set (n = 1,017), and one third were assigned to the validation set (n = 509). Multivariate cox regression analysis was performed to identify significant prognostic factors for overall survival to develop the nomogram...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28905657/selecting-a-risk-based-sqc-procedure-for-a-hba1c-total-qc-plan
#8
Sten A Westgard, Hassan Bayat, James O Westgard
BACKGROUND: Recent US practice guidelines and laboratory regulations for quality control (QC) emphasize the development of QC plans and the application of risk management principles. The US Clinical Laboratory Improvement Amendments (CLIA) now includes an option to comply with QC regulations by developing an individualized QC plan (IQCP) based on a risk assessment of the total testing process. The Clinical and Laboratory Standards Institute (CLSI) has provided new practice guidelines for application of risk management to QC plans and statistical QC (SQC)...
September 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28903439/lymph-node-status-in-different-molecular-subtype-of-breast-cancer-triple-negative-tumours-are-more-likely-lymph-node-negative
#9
Ning Liu, Zhigang Yang, Xiaozhen Liu, Yun Niu
BACKGROUND AND OBJECTIVES: To investigate the association between different molecular subtype (MST) and the axillary lymph nodal (ALN) status. MATERIALS AND METHODS: A total of 528 female patients with primary breast cancer were collected. Survival estimates were calculated using the Kaplan-Meier method, univariate and multivariate logistic regression models. RESULTS: Triple negative and Luminal A breast cancers were more frequently node-negative (N0) when compared to Luminal B and Her-2 positive cancers (77...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28900497/pretreatment-nomograms-for-local-and-regional-recurrence-after-radical-radiation-therapy-for-primary-nasopharyngeal-carcinoma
#10
Fo-Ping Chen, Li Lin, Zhen-Yu Qi, Guan-Qun Zhou, Rui Guo, Jiang Hu, Ai-Hua Lin, Jun Ma, Ying Sun
Background: The aim of this study was to build nomograms to predict local recurrence (LR) and regional recurrence (RR) in patients with nasopharyngeal carcinoma (NPC) underwent intensity-modulated radiation therapy (IMRT). Patients and Methods : A total of 1811 patients with non-metastatic NPC treated with IMRT (with or without chemotherapy) between October 2009 and February 2012 at our center were involved for building the nomograms. Nomograms for LR-free rate and RR-free rate at 3- and 5- year were generated as visualizations of Cox proportional hazards regression models, and validated using bootstrap resampling, estimating discrimination and calibration...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28900495/differentially-expressed-lncrnas-in-gastric-cancer-patients-a-potential-biomarker-for-gastric-cancer-prognosis
#11
Xianglong Tian, Xiaoqiang Zhu, Tingting Yan, Chenyang Yu, Chaoqin Shen, Jie Hong, Haoyan Chen, Jing-Yuan Fang
Current studies indicate that long non-coding RNAs (lncRNAs) are frequently aberrantly expressed in cancers and implicated with prognosis in gastric cancer (GC). We intended to generate a multi-lncRNA signature to improve prognostic prediction of GC. By analyzing ten paired GC and adjacent normal mucosa tissues, 339 differentially expressed lncRNAs were identified as the candidate prognostic biomarkers in GC. Then we used LASSO Cox regression method to build a 12-lncRNA signature and validated it in another independent GEO dataset...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28900490/wnt3a-expression-is-associated-with-epithelial-mesenchymal-transition-and-impacts-prognosis-of-lung-adenocarcinoma-patients
#12
Jinming Xu, Wang Lv, Yeji Hu, Luming Wang, Yiqing Wang, Jinlin Cao, Jian Hu
Background: Epithelial-mesenchymal transition (EMT) plays an important role in the invasion and migration during cancer metastasis. Wnt3a is one of the ligands in canonical Wnt/β-catenin signaling pathway, which contributes to the carcinogenesis and progression of lung cancer cell lines. The aim of this study was to evaluate the association between Wnt3a and EMT-related proteins (E-cadherin and N-cadherin), and to further investigate its impact on prognosis of lung adenocarcinoma patients. Methods: A total of 147 lung adenocarcinoma patients were included and their clinicopathological characteristics were collected in this retrospective study...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28895486/iatrogenic-adrenal-insufficiency-secondary-to-combination-therapy-with-elvitegravir-cobicistat-tenofovir-disoproxil-fumarate-emtricitabine-and-interlaminar-triamcinolone-injection-in-an-aids-patient
#13
Chanie Wassner, Sutapa Maiti, Kurt Kodroff, Henry Cohen
We report the first identified case of suspected iatrogenic adrenal insufficiency after an interlaminar injection of triamcinolone acetonide while on concomitant Stribild (elvitegravir 150 mg/cobicistat 150 mg/tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg [EVG/c/TDF/FTC]). A 49-year-old female with HIV on EVG/c/TDF/FTC therapy presented to our endocrinology clinic to be evaluated for suspected Cushing syndrome. Prior to presentation, the patient had been given 2 interlaminar spinal injections of triamcinolone...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28895112/external-validation-of-the-prognostic-nomogram-compass-for-patients-with-peritoneal-carcinomatosis-of-colorectal-cancer
#14
Karel Demey, Albert Wolthuis, Anthony de Buck van Overstraeten, Steffen Fieuws, Vincent Vandecaveye, Eric Van Cutsem, André D'Hoore
BACKGROUND: To optimize outcome, selection of patients for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is critical. Recently, Simkens et al.7 evaluated the peritoneal surface disease severity score (PSDSS) and suggested a new prognostic nomogram, the colorectal peritoneal metastases prognostic surgical score (COMPASS) based on age, peritoneal carcinomatosis index score, locoregional lymph node status, and signet ring cell histology. This COMPASS nomogram had better discriminative ability according to the Harrell c-index than PSDSS (c = 0...
September 11, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28895080/population-pharmacokinetic-and-pharmacodynamic-modeling-of-artemisinin-resistance-in-southeast-asia
#15
Jesmin Lohy Das, Arjen M Dondorp, Francois Nosten, Aung Pyae Phyo, Warunee Hanpithakpong, Pascal Ringwald, Pharath Lim, Nicholas J White, Mats O Karlsson, Martin Bergstrand, Joel Tarning
Orally administered artemisinin-based combination therapy is the first-line treatment against uncomplicated P. falciparum malaria worldwide. However, the increasing prevalence of artemisinin resistance is threatening efforts to treat and eliminate malaria in Southeast Asia. This study aimed to characterize the exposure-response relationship of artesunate in patients with artemisinin sensitive and resistant malaria infections. Patients were recruited in Pailin, Cambodia (n = 39), and Wang Pha, Thailand (n = 40), and received either 2 mg/kg/day of artesunate mono-therapy for 7 consecutive days or 4 mg/kg/day of artesunate monotherapy for 3 consecutive days followed by mefloquine 15 and 10 mg/kg for 2 consecutive days...
September 11, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28893792/influence-of-mechanical-ventilation-on-vancomycin-pharmacokinetics-administered-by-continuous-infusion-in-critically-ill-patients
#16
Susanna Edith Medellín-Garibay, Silvia Romano-Moreno, Pilar Tejedor-Prado, Noelia Rubio-Álvaro, Aida Rueda-Naharro, Miguel Angel Blasco-Navalpotro, Benito García, Emilia Barcia
Pathophysiological changes involved on drug disposition in critically ill patients, should be considered on the dosing optimization of vancomycin administered by continuous infusion, and certain strategies must be applied to reach therapeutic targets on the first day of treatment. The aim of this study was to develop a population pharmacokinetic model of vancomycin to determine clinical covariates, including mechanical ventilation, that influence the wide variability of this antimicrobial. Vancomycin plasma concentrations from 54 critically ill patients were simultaneously analyzed by population pharmacokinetic approach...
September 11, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28893427/nomograms-for-echocardiographic-right-ventricular-sub-costal-view-dimensions-in-healthy-caucasian-children-a-new-approach-to-measure-the-right-ventricle
#17
Massimiliano Cantinotti, Raffaele Giordano, Marco Scalese, Eliana Franchi, Giulia Corana, Nadia Assanta, Crocetti Maura, Marotta Marco, Sabrina Molinaro, Martin Koestenberger, Giorgio Iervasi
BACKGROUND: The sub-costal examination of the heart is part of routine examination in pediatric echocardiography, and has the advantage to visualize also the infundibulum part of the right ventricle (RV). Despite this fact, currently nomograms for sub-costal RV dimensions are lacking. METHODS: We prospectively studied healthy Caucasian Italian children by two-dimensional echocardiography. Measurements included: sub-costal end diastolic basal-apical and latero-lateral diameters, end diastolic and end systolic area, 4 chamber end diastolic and end systolic area and length, end diastolic basal (RV1) and mid-cavity (RV2) diameters...
September 8, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28893132/prediction-of-infection-caused-by-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-development-of-a-clinical-decision-making-nomogram
#18
Ana García-Tello, Helena Gimbernat, Cristina Redondo, Elisa Meilán, David M Arana, Juana Cacho, Juan F Dorado, Javier C Angulo
OBJECTIVE: This study aimed to assess the population at risk of infection by extended-spectrum beta-lactamase (ESBL)-producing organisms, using clinical criteria. MATERIALS AND METHODS: All urine cultures positive for Enterobacteriaceae in a Spanish hospital department from January 2010 to 2014 were reviewed. All isolates with ESBL-positive strains were collected, and isolates received during the first week of each month with ESBL-negative strains from symptomatic patients hospitalized or admitted to the emergency room...
September 11, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28887511/hemoglobin-level-a-prognostic-factor-for-nasal-extranodal-natural-killer-t-cell-lymphoma-patients-from-stage-i-to-iv-a-validated-prognostic-nomogram
#19
Jianzhong Cao, Shengmin Lan, Liuhai Shen, Hongwei Si, Huan Xiao, Qiang Yuan, Xue Li, Hongwei Li, Ruyuan Guo
Although nasal extranodal natural killer/T-cell lymphoma (nasal ENKL) shares some prognostic factors with other lymphomas, seldom studies had explored the prognostic value of hemoglobin. The ENKL cases in stage I-IV during 2000 to 2015 were collected from two medical centers (group A, n = 192), and were randomly divided into the group B (n = 155) and C (n = 37). Although the significant factors identified by the univariate analysis differed between the group A and B, the multivariate Cox regression indicated the same factors...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28882456/predicting-adverse-events-in-patients-undergoing-hepatectomy-validation-of-preoperative-nomogram-and-risk-score
#20
Travis P Spaulding, Robert C G Martin
BACKGROUND/PURPOSE: Much research exists on preoperative measures of postoperative mortality in the surgical treatment of liver malignancies, but little on morbidity, a more common outcome. This study aims (i) to validate the published calculations as acceptable measures of postoperative mortality and (ii) to assess the value of these published measures in predicting postoperative morbidity. METHODS: Data were collected from a prospectively managed dataset of 1059 hepatectomies performed in Louisville, Kentucky from December 1990 to April 2014...
September 4, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
keyword
keyword
32523
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"