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https://www.readbyqxmd.com/read/29240287/comparative-study-of-femtosecond-laser-assisted-cataract-surgery-and-conventional-phacoemulsification-in-vitrectomised-eyes
#1
Ellen F Wang, Andrew Worsley, Philip J Polkinghorne
IMPORTANCE: To compare the safety and outcomes of femtosecond laser assisted cataract surgery and conventional phacoemulsification in post-vitrectomy eyes. BACKGROUND: To compare visual outcomes and adverse outcomes of femtosecond laser assisted cataract surgery and conventional phacoemulsification in vitrectomised eyes. DESIGN: Single surgeon, retrospective study set in a private clinic in Auckland, New Zealand. Patients selected in a chronological manner, without masking or randomisation...
December 14, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29239906/nerve-growth-factor-changes-and-corneal-nerve-repair-after-keratoplasty
#2
Yueji Pan, Fang Liu, Xiaofeng Qi, Yuan Hu, Feihong Xu, Hui Jia
SIGNIFICANCE: Measured tear concentration of nerve growth factor is correlated with postoperative corneal reinnervation among patients who undergo keratoplasty. This may be a future therapeutic target for post-keratoplasty corneal nerve regeneration. PURPOSE: To determine the relationship between changes in the content of nerve growth factor (NGF) in tear fluid and corneal subepithelial nerve regeneration in patients after keratoplasty. METHODS: In this retrospective study, 30 eyes of 28 patients (15 males, 13 females; mean age 42...
December 13, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29239864/trabeculectomy-outcomes-after-glaucoma-drainage-device-surgery
#3
Reza Alizadeh, Handan Akil, James Tan, Simon K Law, Joseph Caprioli
PURPOSE: To evaluate outcomes of trabeculectomy with adjunctive Mitomycin-C (MMC) in patients with uncontrolled intraocular pressure (IOP) after glaucoma drainage device implantation (GDD). METHODS: Consecutive patients who had undergone a trabeculectomy after GDD were reviewed. The primary outcome was surgical success with stratified IOP targets based on the following criteria: (A) IOP <18▒mm Hg and IOP reduction of 20%; (B) IOP <15▒mm Hg and IOP reduction of 25%; (C) IOP <12▒mm Hg and IOP reduction of 30%...
December 12, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29239527/removal-of-epileptically-compromised-tissue-in-the-frontal-cortex-restores-oculomotor-selection-in-the-antisaccade-task
#4
Stefan Van der Stigchel, Frans S S Leijten, Mariska J Vansteensel, Hendrik Chris Dijkerman, Nick F Ramsey, Zachary V Freudenburg
The frontal cortex is heavily involved in oculomotor selection. Here, we investigated the neural correlates of eye movement selection during an antisaccade task in a young epileptic patient in whom the seizure focus included the frontal cortex and affected its function. Before resection surgery, the patient had difficulty in performing correct antisaccades towards the visual field contralateral to the seizure focus. Because the FEF is the only area in the human frontal cortex that is known to have a lateralized oculomotor function in the antisaccade task, this behavioural imbalance between the two visual fields suggests a disruption of FEF functioning by the nearby seizure focus...
December 14, 2017: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29238161/prevalence-and-causes-of-blindness-visual-impairment-and-cataract-surgery-in-timor-leste
#5
Marcelino Correia, Taraprasad Das, Julia Magno, Bernadette M Pereira, Valerio Andrade, Hans Limburg, John Trevelyan, Jill Keeffe, Nitin Verma, Yuddha Sapkota
Purpose: To estimate the prevalence and causes of blindness and visual impairment, cataract surgical coverage (CSC), visual outcome of cataract surgery, and barriers to uptake cataract surgery in Timor-Leste. Method: In a nationwide rapid assessment of avoidable blindness (RAAB), the latest population (1,066,409) and household data were used to create a sampling frame which consists of 2,227 population units (study clusters) from all 13 districts, with populations of 450-900 per unit...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29237925/corneal-endothelial-cell-loss-in-femtosecond-laser-assisted-descemet-s-stripping-automated-endothelial-keratoplasty-a-12-month-follow-up-study
#6
Yun Feng, Hong-Qiang Qu, Jing Ren, Philipp Prahs, Jing Hong
BACKGROUND: Descemet's stripping automated endothelial keratoplasty (DSAEK) surgery offers a more standardized approach and reliable method to create corneal grafts with an instrument such as a microkeratome. With the development of Descemet's membrane endothelial keratoplasty, an excellent clinical outcome is seen in the treatment of corneal endothelial dysfunctions, which indicates that thinner corneal graft results in better clinical outcome. With the recent development of the femtosecond laser, ultrathin corneal graft preparation has become possible...
December 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29237924/glaucoma-in-patients-with-eyes-close-to-areas-affected-by-port-wine-stain-has-lateral-and-gender-predilection
#7
Yue Wu, Ru-Jing Yu, Di Chen, Li Xu, Mao Li, Li Zhu, Chun-Yu Guo, Wen-Yi Guo
BACKGROUND: The location of facial port-wine stain (PWS) may be helpful for predicting some associated anomalies; high glaucoma incidence is found in patients with eyes close to PWS-affected areas (V1, ophthalmic branch area of the trigeminal nerve). This study aimed to investigate the characteristics of glaucoma in V1-affected PWS. METHODS: A total of 569 patients with V1 area-affected PWS were reviewed in the study. The large series was based on the referral system between the Department of Plastic and Reconstructive Surgery and the Department of Ophthalmology...
December 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29237498/vitreous-hemorrhage-and-rhegmatogenous-retinal-detachment-that-developed-after-botulinum-toxin-injection-to-the-extraocular-muscle-case-report
#8
Dong Hyun Lee, Jinu Han, Sueng-Han Han, Sung Chul Lee, Min Kim
BACKGROUND: The authors report a case of a rare complication that occurred after botulinum toxin injection to the extraocular muscle, which was easily overlooked and successfully corrected by surgery. CASE PRESENTATION: A 34-year-old female patient visited our clinic for diplopia and ocular motility disorder after removal of an epidermoid tumor of the brain. At her initial visit, her best-corrected visual acuity (BCVA) was 20/20 for both eyes. An alternate cover test showed 45 prism-diopter esotropia and 3 prism-diopter hypertropia in the right eye...
December 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29234549/bilateral-mycobacterium-chelonae-keratitis-after-phacoemulsification-cataract-surgery
#9
Jaime D Martinez, Guillermo Amescua, Jesus Lozano-Cárdenas, Leejee H Suh
The purpose of this manuscript is to report the case of an 81-year-old patient who presented with bilateral keratitis after phacoemulsification surgery. Cultures came back positive for Mycobacterium chelonae. Despite aggressive topical and systemic antimicrobial treatment, the patient developed a corneal perforation in both eyes, treated with corneal glue in the right eye and corneoscleral patch in the left eye. After two years of follow-up, patient was free of infection in the right eye with visual acuity of 20/200 and the left eye progressed to phthisis bulbi...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29234230/traumatic-eye-ball-luxation-a-stepwise-approach-to-globe-salvage
#10
Himika Gupta, Srivalli Natarajan, Sushrut Vaidya, Shipra Gupta, Dinesh Shah, Raj Merchant, Shrikant Deshpande
Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF) leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG) biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29234222/anatomical-and-functional-outcomes-of-retinectomies-in-retinal-detachments-complicated-by-proliferative-vitreoretinopathy
#11
Mohammad Idrees Adhi, Nisar Siyal, Sumbul Aziz
Purpose: To study anatomical and functional outcomes of retinectomies in rhegmatogenous retinal detachments complicated by proliferative vitreoretinopathy. Methods: This is a retrospective interventional consecutive case series of eyes with rhegmatogenous retinal detachments complicated by advanced proliferative vitreoretinopathy and managed by relaxing retinectomy over a period of seventeen years. Three-port pars plana vitrectomy included core vitrectomy and removal of all epi-retinal membranes...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29233750/fibrin-hydrogels-as-a-xenofree-and-rapidly-degradable-support-for-transplantation-of-retinal-pigment-epithelium-monolayers
#12
Jarel K Gandhi, Zahid Manzar, Lori A Bachman, Cynthia Andrews-Pfannkoch, Travis Knudsen, Matthew Hill, Hannah Schmidt, Raymond Iezzi, Jose S Pulido, Alan D Marmorstein
Recent phase 1 trials of embryonic stem cell and induced pluripotent stem cell (iPSCs) derived RPE transplants for the treatment of macular degeneration have demonstrated the relative safety of this process. However, there is concern over clumping, thickening, folding, and wrinkling of the transplanted RPE. To deliver a flat RPE monolayer, current phase 1 trials are testing synthetic substrates for RPE transplantation. These substrates, however, cause localized inflammation and fibrosis in animal models due to long degradation times...
December 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29233738/prevalence-of-transforming-growth-factor-%C3%AE-induced-gene-corneal-dystrophies-in-chinese-refractive-surgery-candidates
#13
Yanzheng Song, Mingshen Sun, Ningli Wang, Xingtao Zhou, Jing Zhao, Qinmei Wang, Shihao Chen, Yingping Deng, Lemei Qiu, Yueguo Chen, Anthony J Aldave, Fengju Zhang
PURPOSE: To determine the prevalence of the transforming growth factor (TGF) β-induced gene corneal dystrophies in refractive surgery candidates in China. SETTING: Five hospitals in China. DESIGN: Prospective case series. METHOD: Refractive surgical candidates from 5 preselected eye hospitals/centers in China were recruited after providing informed consent. All patients had slitlamp biomicroscopy and collection of a buccal swab as a source of DNA for screening of the TGF β-induced gene for the 5 most common mutations associated with Reis-Bückler corneal dystrophy, Thiel-Behnke corneal dystrophy, granular corneal dystrophy type 1, granular corneal dystrophy type 2, and lattice corneal dystrophy type 1...
December 9, 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29232338/internal-limiting-membrane-peeling-versus-inverted-flap-technique-for-treatment-of-full-thickness-macular-holes-a-comparative-study-in-a-large-series-of-patients
#14
Stanislao Rizzo, Ruggero Tartaro, Francesco Barca, Tomaso Caporossi, Daniela Bacherini, Fabrizio Giansanti
BACKGROUND: The inverted flap (IF) technique has recently been introduced in macular hole (MH) surgery. The IF technique has shown an increase of the success rate in the case of large MHs and in MHs associated with high myopia. This study reports the anatomical and functional results in a large series of patients affected by MH treated using pars plana vitrectomy and gas tamponade combined with internal limiting membrane (ILM) peeling or IF. METHODS: This is a retrospective, consecutive, nonrandomized comparative study of patients affected by idiopathic or myopic MH treated using small-gauge pars plana vitrectomy (25- or 23-gauge) between January 2011 and May 2016...
December 8, 2017: Retina
https://www.readbyqxmd.com/read/29232337/retinal-telangiectasia-in-patients-with-pathologic-myopia-a-case-series
#15
Boya Lei, Ruiping Gu, Chen Jiang, Gezhi Xu
PURPOSE: To describe the characteristics of retinal telangiectasia in eyes with pathologic myopia. METHODS: The study included 10 patients (18 eyes) who were diagnosed with pathologic myopia combined with retinal telangiectasia. The patients visited our retinal clinic every 3 months. Nine eyes underwent vitrectomy for vision-threatening complications after diagnosis. All eyes underwent comprehensive ophthalmologic examinations including multimodal retinal imaging at presentation and at each follow-up...
December 8, 2017: Retina
https://www.readbyqxmd.com/read/29232333/structural-analysis-and-comprehensive-surgical-outcomes-of-the-sutureless-intrascleral-fixation-of-secondary-intraocular-lenses-in-human-eyes
#16
Bozho Todorich, Maxwell S Stem, Keshav Kooragayala, Aristomenis Thanos, Lisa J Faia, George A Williams, Tarek S Hassan, Maria A Woodward, Jeremy D Wolfe
PURPOSE: To describe surgical outcomes and structural characteristics of intraocular lenses (IOLs) implanted with transconjunctival sutureless intrascleral (SIS) fixation in human eyes. DESIGN: Retrospective interventional surgical case series involving live and cadaveric human eyes. METHODS: In this study, we investigated the surgical outcomes and structural anatomy of secondary IOLs implanted with the SIS technique in human eyes. All cases involving SIS IOL fixation performed at a single academic center from January 1, 2012, through July 30, 2016, were reviewed to describe the surgical technique, common indications, clinical outcomes, and the rate of common operative complications...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29232332/outcomes-of-repeat-pars-plana-vitrectomy-after-failed-surgery-for-proliferative-vitreoretinopathy
#17
Ramsudha Narala, Nariman Nassiri, Chaesik Kim, Christian Mehregan, Sneha Padidam, Gary W Abrams
PURPOSE: To evaluate outcomes of repeat pars plana vitrectomy for proliferative vitreoretinopathy after previous failed pars plana vitrectomy. METHODS: This is a retrospective case series including 51 eyes of 50 patients who underwent repeat surgery after failed previous pars plana vitrectomy for proliferative vitreoretinopathy from 2000 to 2015 at the Kresge Eye Institute, Detroit, MI. Patients were classified into successful and unsuccessful groups. Success was defined as retinal reattachment, silicone oil removed, and best-corrected visual acuity (BCVA) ≥5/200 at the final follow-up visit...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29232331/theoretical-gas-concentrations-achieving-100-fill-of-the-vitreous-cavity-in-the-postoperative-period-a-gas-eye-model-study
#18
Tom H Williamson, Jean-Yves Guillemaut, Sheldon K Hall, Joseph C Hutter, Tony Goddard
PURPOSE: To determine the concentrations of different gas tamponades in air to achieve 100% fill of the vitreous cavity postoperatively and to examine the influence of eye volume on these concentrations. METHODS: A mathematical model of the mass transfer dynamics of tamponade and blood gases (O2, N2, and CO2) when injected into the eye was used. Mass transfer surface areas were calculated from published anatomical data. The model has been calibrated from published volumetric decay and composition results for three gases sulphahexafluoride (SF6), hexafluoroethane (C2F6), or perfluoropropane (C3F8)...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29232330/foveal-avascular-zone-area-analysis-using-optical-coherence-tomography-angiography-before-and-after-idiopathic-epiretinal-membrane-surgery
#19
Yorihisa Kitagawa, Hiroyuki Shimada, Ari Shinojima, Hiroyuki Nakashizuka
PURPOSE: To determine the size of the foveal avascular zone (FAZ) by optical coherence tomography angiography before and after idiopathic epiretinal membrane surgery. METHODS: Thirteen consecutive patients (13 eyes) with unilateral epiretinal membrane were studied retrospectively. Optical coherence tomography angiography was used to measure the FAZ area within 3 mm × 3 mm scans of the superficial (superficial FAZ) and deep plexus layers (deep FAZ) before and 6 months after vitrectomy...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29232194/persistent-ventricular-bigeminy-during-anesthesia-in-pediatric-patients-a-case-report-of-an-11-year-old-child
#20
Sheetal Dalal, Vikas Chaudhari
An 11-year-old male child with fractures in both bones in his left forearm presented for open reduction and internal fixation. The pre-anesthetic check-up and investigations did not reveal any pre-existing underlying cardio-respiratory disease. The patient had an uneventful peri-operative period during the operation and was comfortable without any anxiety or restlessness. After an uneventful induction and intubation as per routine protocol, the patient received 600 mg of amoxicillin+clavunate intravenously as an antibiotic...
December 12, 2017: Journal of Basic and Clinical Physiology and Pharmacology
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