keyword
MENU ▼
Read by QxMD icon Read
search

polypoidal choroidal vasculopathy

keyword
https://www.readbyqxmd.com/read/27930435/polypoidal-choroidal-vasculopathy-a-clinicopathologic-study
#1
Kareem Moussa, Michele M Bloomer, Daniel M Schwartz, Carolyn K Pan, Brian C Toy, Joseph B Crawford, Armin R Afshar
PURPOSE: To present a unique case of polypoidal choroidal vasculopathy presenting as a blind, painful eye with a suspected intraocular mass, and to correlate clinical findings with histopathologic studies. METHODS: Clinical case report and literature review. RESULTS: A 58-year-old Vietnamese man presented with a blind, painful eye with concern for an intraocular mass. B-scan ultrasonography showed massive intraocular hemorrhage and could not rule out a tumor...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27928695/one-year-outcomes-of-a-treat-and-extend-regimen-of-intravitreal-aflibercept-for-polypoidal-choroidal-vasculopathy
#2
Mio Hosokawa, Yuki Morizane, Masayuki Hirano, Shuhei Kimura, Fumiaki Kumase, Yusuke Shiode, Shinichiro Doi, Shinji Toshima, Mika Hosogi, Atsushi Fujiwara, Toshiharu Mitsuhashi, Fumio Shiraga
PURPOSE: To evaluate the 1-year treatment outcomes of intravitreal aflibercept injections (IVA) using a treat-and-extend regimen for polypoidal choroidal vasculopathy (PCV). METHODS: Thirty-seven eyes with treatment-naive PCV treated with IVA using a treat-and-extend regimen for 1 year were reviewed retrospectively. The main outcome measures were changes in the best-corrected visual acuity (BCVA) and central retinal thickness (CRT), and the treatment interval at 1 year...
December 7, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27913869/ranibizumab-for-vascularized-pigment-epithelial-detachment-1-year-anatomic-and-functional-results
#3
Olivier Chevreaud, Hassiba Oubraham, Salomon Y Cohen, Camille Jung, Rocio Blanco-Garavito, Farah Gherdaoui, Eric H Souied
PURPOSE: To assess the anatomical and functional efficacy of ranibizumab on vascularized pigment epithelial detachment (V-PED) secondary to neovascular age-related macular degeneration (nAMD). METHODS: One hundred and nine patients (116 eyes) were retrospectively selected from medical records of 2097 patients who benefited from intravitreal injection between January 2011 and June 2013 in a tertiary-care University-based Department of Ophthalmology. Inclusion criteria were: nAMD, treatment-naive eyes, presence of V-PED higher than 250 μm, intravitreal ranibizumab with a loading phase, followed by a pro-re-nata regimen, and 1-year follow-up...
December 3, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27913447/comparison-of-oct-angiography-and-indocyanine-green-angiographic-findings-with-subtypes-of-polypoidal-choroidal-vasculopathy
#4
Koji Tanaka, Ryusaburo Mori, Akiyuki Kawamura, Hiroyuki Nakashizuka, Yu Wakatsuki, Mitsuko Yuzawa
PURPOSE: To compare the findings of optical coherence tomography angiography (OCTA) with indocyanine green angiography (ICGA) in polypoidal choroidal vasculopathy (PCV) that was divided into two types: polypoidal choroidal neovascularisation (CNV) and typical PCV (type 2 PCV). METHODS: We studied a retrospective case series of 32 patients with treatment-naïve PCV (24 men, eight women; mean age 65.4 years). PCV was categorised into polypoidal CNV (type 1 PCV) and type 2 PCV based on ICGA findings...
December 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27910906/analysis-of-the-serum-lipid-profile-in-polypoidal-choroidal-vasculopathy
#5
Miaoling Li, Xiongze Zhang, Nanying Liao, Baikang Ye, Yuting Peng, Yuying Ji, Feng Wen
Polypoidal choroidal vasculopathy (PCV), the predominant subtype of neovascular age-related macular degeneration in the Asian population, is associated with genetic polymorphism of lipid metabolism. In this study, we performed the untargeted lipidomics approach of ultra-performance liquid chromatography coupled with mass spectrometry (UPLC-MS) to reveal the potential discriminating lipid profile of PCV patients in serum (21 PCV patients and 19 age-matched controls). Unsupervised principal component, supervised orthogonal partial least squares analysis, correlation analysis, and heatmap analysis were performed with the data obtained by UPLC-MS...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27848983/treatment-of-polypoidal-choroidal-vasculopathy-by-photodynamic-therapy-aflibercept-and-dexamethasone-triple-therapy
#6
Mary Ho, Donald C F Woo, Vesta C K Chan, Alvin L Young, Marten E Brelen
Polypoidal choroidal vasculopathy is a relatively common type of degenerative macular disease among the Chinese population. This study aims to describe the therapeutic responses to combination therapy with photodynamic therapy, intravitreal aflibercept and intravitreal dexamethasone in patients with polypoidal choroidal vasculopathy. A prospective series of 17 eyes of 13 patients suffering from treatment-naïve polypoidal choroidal vasculoapathy were recruited. All cases received triple therapy with photodynamic therapy, intravitreal aflibercept and intravitreal dexamethasone and one year outcomes were reported...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27843227/combined-argon-laser-photocoagulation-and-antivascular-endothelial-growth-factor-for-management-of-macular-polypoidal-choroidal-vasculopathy
#7
Parveen Sen, S Vinay Kumar, Muna Bhende, Tarun Sharma
AIM: To evaluate the efficacy of combination therapy of argon laser photocoagulation and intravitreal antivascular endothelial growth factor (VEGF) injection in idiopathic polypoidal choroidal vasculopathy (PCV) involving macula. MATERIALS AND METHODS: A retrospective interventional study involving 12 eyes of 11 patients diagnosed with PCV involving the macula on indocyanine green angiography (ICGA). Intravitreal anti-VEGF was given in eyes with significant subretinal/sub retinal pigment epithelium hemorrhage or exudation...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27828911/characterization-and-differentiation-of-polypoidal-choroidal-vasculopathy-using-swept-source-optical-coherence-tomography-angiography
#8
Chui Ming Gemmy Cheung, Yasuo Yanagi, Aditi Mohla, Shu Yen Lee, Ranjana Mathur, Choi Mun Chan, Ian Yeo, Tien Yin Wong
PURPOSE: To determine the correlation and agreement between swept-source optical coherence tomography angiography (SS-OCT-A) with fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral domain OCT (SD-OCT) in characterizing polypoidal choroidal vasculopathy (PCV) and in differentiating eyes with typical age-related macular degeneration (t-AMD). METHODS: This study included 32 and 54 eyes with t-AMD and PCV, respectively, who underwent SS-OCT-A, SD-OCT, fluorescein angiography, and indocyanine green angiography...
November 8, 2016: Retina
https://www.readbyqxmd.com/read/27813526/comparison-of-indocyanine-green-angiography-and-optical-coherence-tomographic-angiography-in-polypoidal-choroidal-vasculopathy
#9
K Takayama, Y Ito, H Kaneko, K Kataoka, T Sugita, R Maruko, K Hattori, E Ra, F Haga, H Terasaki
PurposeTo compare optical coherence tomographic angiography (OCTA) and indocyanine green angiography (ICGA) images for detecting polypoidal lesions (PLs) and branching vascular networks (BVNs), and to measure the polypoidal areas (PAs) in patients with polypoidal choroidal vasculopathy (PCV).MethodsAll patients underwent ICGA, optical coherence tomography (OCT), and OCTA. We compared the detection sensitivity for PL and BVN, as evaluated by the ICGA and OCTA images. Furthermore, PA measured by ICGA was divided into two groups: one in which the area could be measured by OCTA (ICGA(+)OCTA(+)) and the other in which the area could not be measured by OCTA (ICGA(+)OCTA(-))...
November 4, 2016: Eye
https://www.readbyqxmd.com/read/27800252/treatment-outcomes-in-patients-with-polypoidal-choroidal-vasculopathy
#10
Işıl Sayman Muslubaş, Mümin Hocaoğlu, Serra Arf, Hakan Özdemir, Murat Karaçorlu
OBJECTIVES: To report outcomes of photodynamic therapy (PDT) and combined therapy with PDT and intravitreal bevacizumab (IVB) in patients with polypoidal choroidal vasculopathy (PCV). MATERIALS AND METHODS: Thirty-four eyes of 31 patients with subfoveal PCV were evaluated. Nine eyes were treated with PDT and 25 eyes treated with combined therapy of PDT and IVB. All eyes had a follow-up period of at least 12 months. In this retrospective study the demographic features, best corrected visual acuity, fundus color photography, optical coherence tomography, fluorescein angiography and indocyanine green angiography of the 34 eyes were evaluated...
January 2016: Turk J Ophthalmol
https://www.readbyqxmd.com/read/27787563/association-of-abcg1-with-neovascular-age-related-macular-degeneration-and-polypoidal-choroidal-vasculopathy-in-chinese-and-japanese
#11
Li Ma, Ke Liu, Motokazu Tsujikawa, Haoyu Chen, Marten E Brelen, Vesta C K Chan, Timothy Y Y Lai, Kaori Sayanagi, Chicako Hara, Noriyasu Hashida, Pancy O S Tam, Alvin L Young, Weiqi Chen, Kohji Nishida, Chi Pui Pang, Li Jia Chen
Purpose: We investigated the association of the ATP-binding cassette, subfamily G, member 1 (ABCG1) gene with polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD) in independent Chinese and Japanese cohorts. Methods: A total of 12 haplotype-tagging single-nucleotide polymorphisms (SNPs) and the SNP rs57137919 in the ABCG1 gene were first analyzed in a Hong Kong Chinese cohort of 235 nAMD, 236 PCV, and 365 controls, using TaqMan genotyping assays...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27779169/comparison-of-the-1-year-outcomes-of-conbercept-therapy-between-two-different-angiographic-subtypes-of-polypoidal-choroidal-vasculopathy
#12
Yong Cheng, Xuan Shi, Jin-Feng Qu, Ming-Wei Zhao, Xiao-Xin Li
BACKGROUND: Polypoidal choroidal vasculopathy (PCV) is characterized by the presence of polyps with or without a branching vascular network and more prevalent among Asians. The aim of this study was to compare the outcomes of conbercept therapy between two different angiographic subtypes of PCV. METHODS: Fifty-eight patients of PCV were classified into two phenotypes according to indocyanine green angiography (ICGA). In Type 1, both feeder and draining vessels are visible on ICGA and network vessels are numerous...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27769325/hypertension-as-a-risk-factor-for-recurrent-subretinal-hemorrhage-in-polypoidal-choroidal-vasculopathy
#13
Yoo-Ri Chung, Eoi Jong Seo, Yong Hyun Kim, Hongseok Yang, Kihwang Lee
OBJECTIVE: To investigate the relationship between hypertension and recurrent subretinal hemorrhage (SRH) in eyes with polypoidal choroidal vasculopathy (PCV). DESIGN: Retrospective, comparative case series. PARTICIPANTS: Thirty-eight eyes of 38 patients with PCV. METHODS: Ocular findings and clinical features were analyzed retrospectively in patients with PCV enrolled from January 2011 to December 2013. The patients were divided into 2 groups according to the presence of recurrent SRH after successful initial treatment (rebleeding vs nonrebleeding) and were subdivided into those with and without hypertension, based on history of hypertension, systolic blood pressure (SBP) >150 mm Hg...
October 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27755377/fluorescein-assisted-subretinal-tissue-plasminogen-activator-tpa-delivery-for-submacular-hemorrhage
#14
Mohammed Ali Khan, Abtin Shahlaee, Alok S Bansal, Joseph I Maguire
PURPOSE: To describe a surgical technique for fluorescein-assisted subretinal tissue plasminogen activator delivery during pars plana vitrectomy for submacular hemorrhage. METHODS: Retrospective, interventional, consecutive case series. RESULTS: Six eyes of 6 patients were reviewed. Etiology of submacular hemorrhage was age-related macular degeneration in 2 eyes and polypoidal choroidal vasculopathy in 4 eyes. Twenty-three-gauge pars plana vitrectomy was performed and fluorescein-stained tissue plasminogen activator was injected in the subretinal space through a 41-gauge cannula in all eyes...
October 11, 2016: Retina
https://www.readbyqxmd.com/read/27749785/choroidal-morphology-in-eyes-with-polypoidal-choroidal-vasculopathy-and-normal-or-subnormal-subfoveal-choroidal-thickness
#15
Won Ki Lee, Jiwon Baek, Kunal K Dansingani, Jae Hyung Lee, K Bailey Freund
PURPOSE: To subsegment the choroid in patients with polypoidal choroidal vasculopathy and to determine whether the ratio of choriocapillaris/Sattler layer thickness to total choroidal thickness is decreased at sites of polypoidal pathology. METHODS: Retrospective, observational, cross-sectional study. A total of 320 eyes of 305 patients with polypoidal choroidal vasculopathy were studied with optical coherence tomography and dye angiography. The ratio of choriocapillaris/Sattler layer thickness to total choroidal thickness was calculated at polypoidal lesion sites in eyes with subfoveal choroidal thickness (SFCT) ≤200 μm...
October 3, 2016: Retina
https://www.readbyqxmd.com/read/27725716/detection-of-aqueous-vegf-concentrations-before-and-after-intravitreal-injection-of-anti-vegf-antibody-using-low-volume-sampling-paper-based-elisa
#16
Min-Yen Hsu, Yu-Chien Hung, De-Kuang Hwang, Shang-Chi Lin, Keng-Hung Lin, Chun-Yuan Wang, Hin-Yeung Choi, Yu-Ping Wang, Chao-Min Cheng
Intraocular vascular endothelial growth factor (VEGF) levels play an important role in the pathogenesis of blindness-related diseases, such as age-related macular degeneration (AMD). Here, we aimed to develop a paper-based enzyme-linked immunosorbent assay (P-ELISA) to analyze the suppression of aqueous VEGF concentrations following intravitreal injection (IVI) of anti-VEGF antibody (bevacizumab or ranibizumab). A total of 25 eyes with wet AMD, one with myopic neovascularization, and one with polypoidal choroidal vasculopathy were enrolled in this study...
October 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27709394/subfoveal-choroidal-thickness-in-polypoidal-choroidal-vasculopathy-after-switching-to-intravitreal-aflibercept-injection
#17
(no author information available yet)
No abstract text is available yet for this article.
October 5, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27702940/low-frequency-coding-variants-in-cetp-and-cfb-are-associated-with-susceptibility-of-exudative-age-related-macular-degeneration-in-the-japanese-population
#18
Yukihide Momozawa, Masato Akiyama, Yoichiro Kamatani, Satoshi Arakawa, Miho Yasuda, Shigeo Yoshida, Yuji Oshima, Ryusaburo Mori, Koji Tanaka, Keisuke Mori, Satoshi Inoue, Hiroko Terasaki, Tetsuhiro Yasuma, Shigeru Honda, Akiko Miki, Maiko Inoue, Kimihiko Fujisawa, Kanji Takahashi, Tsutomu Yasukawa, Yasuo Yanagi, Kazuaki Kadonosono, Koh-Hei Sonoda, Tatsuro Ishibashi, Atsushi Takahashi, Michiaki Kubo
AMD is a major cause of blindness in the elderly. Previous sequencing studies of AMD susceptibility genes have revealed the association of rare coding variants in CFH, CFI, C3 and C9 in European population; however, the impact of rare or low-frequency coding variants on AMD susceptibility in other populations is largely unknown. To identify the role of low-frequency coding variants on exudative AMD susceptibility in a Japanese population, we analyzed the association of coding variants of 34 AMD candidate genes in the two-stage design by a multiplex PCR-based target sequencing method...
October 3, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27687988/one-year-outcome-of-combination-therapy-with-intravitreal-aflibercept-and-verteporfin-photodynamic-therapy-for-polypoidal-choroidal-vasculopathy
#19
Wataru Matsumiya, Shigeru Honda, Keiko Otsuka, Akiko Miki, Takayuki Nagai, Hisanori Imai, Sentaro Kusuhara, Makoto Nakamura
PURPOSE: The purpose of the study was to evaluate the 1-year visual and anatomical outcomes of combination therapy with intravitreal aflibercept (IVA) and verteporfin photodynamic therapy (vPDT) for polypoidal choroidal vasculopathy (PCV), and to determine the predictors of a good visual outcome. METHODS: This was a prospective case-series study. Twenty eyes from 20 treatment-naïve PCV patients were treated with combination therapy with IVA and vPDT. Best-corrected visual acuity (BCVA) and morphological parameters including polypoidal lesions in indocyanine green angiography (ICGA) were evaluated over 12 months of follow-up...
September 30, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27681348/enucleation-for-haemophthalmus-secondary-to-choroidal-neovascularisation-in-polypoidal-choroidal-vasculopathy-a-therapeutic-and-diagnostic-dilemma
#20
Noor Aniah Azmi, Amin Ahem, Mushawiahti Mustapha, Mae-Lynn Catherine Bastion
We report a case of enucleation for painful blind eye secondary to recurrent bleeding from choroidal neovascularisation in an eye that was irradiated following presumed metastatic breast carcinoma to the choroid. A 58-year-old woman with a history of treated breast malignancy presented with haemophthalmus and intractable glaucoma in the right eye. One year previously she had presented with right vitreous haemorrhage with subretinal mass that had been irradiated given her history of breast carcinoma. Following irradiation, vitrectomy was performed to clear the blood...
2016: BMJ Case Reports
keyword
keyword
32491
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"