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Rosemary D Higgins, Seetha Shankaran
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neontal Research Network (NRN) was established in 1986 in response to the need for rigorous studies to guide care and management of sick and premature newborns. The network is comprise of clinical centers that perform clinical protocols to investigate the safety and efficay of treatment and management strategies for newborn infants as well as a data cordinating center. Infrastructure is set up for observational and interventional studies as well as neurodevelopmental follow-up of patients...
October 2016: Seminars in Perinatology
Luisa Schonhaut, Marcela Pérez, Sergio Muñoz
INTRODUCTION: There is evidence that children born moderate-to-late preterm (MLP) have a higher risk of hospitalisation, neonatal morbidity, and developmental delay (DD). OBJECTIVE: To determine the association between DD, gestational age, and neonatal morbidity in MLP children. PATIENTS AND METHOD: A case control study design nested in a cohort of MLP children born between 2006 and 2009 at a private hospital located in the Metropolitan area of Santiago...
November 2015: Revista Chilena de Pediatría
G Pados, M Zafrakas, D Tsolakidis, E Assimakopoulos, H Bili, B C Tarlatzis
PURPOSE: The widespread use of assisted reproduction technology (ART) is accompanied by concerns for potential adverse outcomes. The aim of the present study was to evaluate the impact of ART in obstetric and neonatal outcome. METHODS: Data from labor ward records from 913 consecutive births were analyzed retrospectively, and the obstetric and neonatal outcomes of pregnancies after ART were compared with those after natural conception. RESULTS: No major complications were noted after ART...
2012: Clinical and Experimental Obstetrics & Gynecology
K Wong Ramsey, T P Slavin, G Graham, G I Hirata, V Balaraman, L H Seaver
Monozygotic twins with discordant karyotypes are rare. We report a case of monozygotic twins discordant for trisomy 13 by amniocyte karyotypes. Ultrasound revealed multiple congenital anomalies in Twin A (47,XY,+13), none in Twin B (46,XY), and monochorionic-diamniotic placentation. Zygosity testing performed both prenatally and after birth supported monozygosity. Twin A died in the neontal period. Twin B survived and had normal physical examination, but peripheral blood karyotype revealed 20% mosaicism for trisomy 13...
April 2012: Journal of Perinatology: Official Journal of the California Perinatal Association
V I Kaledin, S I Il'nitskaia, E G Kuznetsova, T G Amstislavskaia
A single injection of diethylnitrosamine 50 mg/kg to 12-day old CBA mice led to development of 50.7 +/- 4.8 liver tumor nodules in males and 3.6 +/- 0.8 nodules in females. Only 19.0 +/- 3.6 tumor nodules developed in the liver of males who, prior to the carcinogen, received 5 intraperitoneal injections of monosodium glutamate (2-4 mg/g on alternate days from 1st to 9th days after birth). The glutamate-treated animals' body size diminished, as well as their weights of testes and seminal vesicles and blood testosterone concentration but, as a rule, quantity of body fat increased...
May 2005: Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova
No abstract text is available yet for this article.
March 1963: Archives Françaises de Pédiatrie
M L Druzin, R F Van Vollenhoven
SLE is an autoimmune condition primarily affecting females in their reproductive years. Advances in medical management of SLE, improved understanding of pregnancy complications and the improvement in neontal medicine have allowed females with SLE to have successful pregnancies.
1996: Annales de Médecine Interne
E Gerdin
No abstract text is available yet for this article.
September 9, 1981: Läkartidningen
M Boureau
No abstract text is available yet for this article.
November 1965: Les Cahiers du Collège de Médecine des Hôpitaux de Paris
A W Bulteau
No abstract text is available yet for this article.
April 6, 1968: Medical Journal of Australia
M A Karasek
Microvascular endothelial cells play a central role in inflammation, tumor metastasis, and wound healing. Methods to study these processes in vitro using cells isolated from adult skin, from the inner and the outer segments of the neontal foreskin, and from experimental animals are reviewed. A new modified Iscove's medium supplemented with 2% pre-partum maternal serum, dibutyryl cyclic AMP, isobutyl methylxanthine, thymidine, and hypoxanthine is described. This modified medium supports growth of both adult and neonatal endothelial cells up to seven passages with retention of cytologic markers closely identified with endothelial cells (Weibel-Palade bodies, Factor VIII-associated antigen)...
August 1989: Journal of Investigative Dermatology
M Abercrombie, J E Heaysman
The mutual invasion in culture of a population of standard fibroblasts (chick embryo) and a population of cells from a transplantable mouse sarcoma (MC)M, BAS/56, or 311) or of neontal mouse fibroblasts has been estimated quantitatively. We arranged the confrontation of the pairs of populations by placing primary explants near each other. After fixation, the distance the cells had migrated from each explant was sampled in the space between the explants where they met and at the sides of the explants where they migrated freely...
March 1976: Journal of the National Cancer Institute
(no author information available yet)
The objective of clinical management of the pregnant diabetic woman is to prevent the serious adverse effects of an abnormal glucose environment on the fetus. Neonatal glucose assimilation and insulin release over the first two hours of life were correlated with various indices of maternal carbohydrate metabolism in the third trimester. Of the 31 mothers studied 21 were defined as normal and 10 as having chemical diabetes. Neontal glucose assimilation during the first two hours of life correlated strongly with functions of both maternal glucose tolerance and mean diurnal glucose level, the strongest correlation being with the area under the three-hour oral glucose tolerance curve (P less than 0...
August 16, 1975: British Medical Journal (1857-1980)
F I Martin, G W Dahlenburg, J Russell, P Jeffery
Neonatal hypoglycaemia (blood glucose smaller than 20 mg/100 ml) occurred in the first 6 hours of life in 25 of 34 infants born to diabetic mothers receiving insulin. Despite severe hypoglycaemia (blood glucose smaller than 10 mg/100 ml) in 17, clinical features of hypoglycaemia were absent in all but 2. Hypoglycaemia was not related either to the level of plasma insulin in cord blood, determined as nonextracted immunoreactive insulin, or to the degree of control of maternal blood glucose during pregnancy. The frequent occurrence of severe neonatal hypoglycaemia in the infants born to diabetic mothers receiving insulin appears to be due rather to failure to maintain basal glucose homoeostasis after birth than to hyperinsulinism...
June 1975: Archives of Disease in Childhood
M Geiser
The method of early diagnosis of congenital dislocation of the hip and the results of immediate treatment are described. X-rays are only useful to prove an instability if the hip is dislocated at the moment the X-ray is taken. If the unstable hips are reduced and redislocation is prevented by means of a splint the great majority of the hips show a normal developement. A primarily unstable hip which was stabilised spontaneously or by using a splint for a short time may become unstable again. Nevertheless splinting in the stable positon should not last longer than 1-2 months...
February 1975: Zeitschrift Für Orthopädie und Ihre Grenzgebiete
A A Zalewski, W K Silvers
No abstract text is available yet for this article.
September 1976: Experimental Neurology
J van der Veen
No abstract text is available yet for this article.
February 26, 1977: Nederlands Tijdschrift Voor Geneeskunde
B Burchell, G J Dutton
Phenobarbital pretreatment of pregnant mice (ASH/TO strain) gave rise to approximately equal concentrations of phenobarbital in both maternal and fetal liver. This pretreatment resulted in increased UDP-glucuronyltransferase (GT) activity towards bilirubin in maternal and neonatal liver in fetal liver on days 19 and 20 but in livers from earlier (15-18 day) fetuses GT either was not significantly increased or remained undetectable. Fetal liver is thus not competent to respond to phenobarbital by increasing its GT activity, until just before birth...
1975: Biology of the Neonate
J M Blankson
An analysis of 249 cases of neontal tetanus admitted to Korle-Bu Teaching Hospital, Accra, between January 1971 and December 1974, has been presented. The overall case fatality was 64%. The unfavourable mortality trend over the period of study calls for urgent preventive measures on a largescale, to control the disease.
March 1977: African Journal of Medicine and Medical Sciences
E H Hon, D Zannini, E J Quilligan
No abstract text is available yet for this article.
June 15, 1975: American Journal of Obstetrics and Gynecology
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