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Very low birth weight infant

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https://www.readbyqxmd.com/read/28545652/using-quality-improvement-to-increase-human-milk-use-for-preterm-infants
#1
Margaret G Parker, Aloka L Patel
This review will provide an overview of quality improvement methods that have been used to improve human milk use (mother's own milk and donor milk) for very low-birth-weight infants in the hospital setting in the last decade. We will review the following: (1) evidence-based practices known to increase mother's own milk for very low-birth-weight infants; (2) individual hospitals with exemplary lactation programs and past and current US-based statewide quality improvement collaboratives focused on increasing mother's own milk; and (3) existing quality metrics for human milk and gaps in metrics...
May 23, 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28539199/respiratory-severity-score-and-extubation-readiness-in-very-low-birth-weight-infants
#2
Maroun J Mhanna, Narayan P Iyer, Scott Piraino, Mohit Jain
BACKGROUND: The respiratory severity score (RSS) is a byproduct of mean airway pressure (MAP) and fraction of inspired oxygen (FiO2). We sought to determine whether RSS could be used as a screening tool to predict extubation readiness in very low birth weight (VLBW) infants. METHODS: In a retrospective cohort study, medical records of all VLBW infants admitted to our unit (6/1/09-2/28/12) were reviewed for infants' demographics, prenatal characteristics, and medication use...
May 10, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28537798/neonatal-morbidity-count-is-associated-with-a-reduced-likelihood-of-achieving-recommendations-for-protein-lipid-and-energy-in-very-low-birth-weight-infants-a-prospective-cohort-study
#3
Dawn V Y Ng, Sharon Unger, Michelle Asbury, Alex Kiss, Rosine Bishara, Nicole Bando, Chris Tomlinson, Sharyn Gibbins, Deborah L O'Connor
BACKGROUND: Serious morbidity may elevate nutrient requirements and affect adherence to feeding guidelines for very low birth weight (VLBW) infants. An understanding of factors affecting nutrient intakes of VLBW infants will facilitate development of strategies to improve nutrient provision. Our aim was to examine the impact of neonatal morbidity count on achieving recommended nutrient intakes in VLBW infants. METHODS: VLBW infants enrolled in the Donor Milk for Improved Neurodevelopmental Outcomes trial (ISRCTN35317141, n = 363) were included...
May 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28531098/increase-in-weight-in-low-birth-weight-and-very-low-birth-weight-infants-fed-fortified-breast-milk-versus-formula-milk-a-retrospective-cohort-study
#4
Kris Yuet Wan Lok, Pui Hing Chau, Heidi Sze Lok Fan, Kam Ming Chan, Bill H Chan, Genevieve P C Fung, Marie Tarrant
There has been a dramatic rise in preterm births in developed countries owing to changes in clinical practices and greater use of assisted reproductive techniques. However, few studies have examined the growth and outcomes of preterm infants according to the type of feeding (with fortified breast milk or formula). The purpose of this study was to examine the effect of breast milk feedings and formula on the growth and short-term outcomes of preterm infants in Hong Kong. In a single-center retrospective cohort study, we included 642 preterm infants at gestational age <37 weeks with birth weights <2200 g...
May 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28520106/prophylactic-sustained-inflation-is-just-one-step-to-preventing-bronchopulmonary-dysplasia
#5
G Lista, I Bresesti
I am glad to see that the Sustained Lung Inflation (SLI) trial (1) still draws a great deal of attention and I would like to clarify some aspects of the trial, in response to the comments by Gupta and Argarwal (2) in Acta Paediatrica. A meta-analysis carried out in 2016 demonstrated that starting non-invasive respiratory support from birth could reduce the incidence of bronchopulmonary dysplasia and death. However, about 50% of very low birth weight infants who are initially on nasal continuous positive airway pressure need subsequent intubation and mechanical ventilation...
May 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28514918/does-vitamin-d-deficiency-affect-placental-inflammation-or-infections-among-very-low-birth-weight-infants
#6
Subhash Puthuraya, Sreenivas Karnati, S Nadya J Kazzi, Faisal Qureshi, Suzanne M Jacques, Ronald Thomas
OBJECTIVE: Examine the association between placental inflammation and neonatal infections and 25OH D levels at birth among VLBWI. STUDY DESIGN: Serum 25OH D levels were measured in 89 VLBWI (≤1250g) and 47 mothers on day one, and in 78 infants on day 21. Placentas were examined for maternal and fetal inflammation. Infants were divided into deficient (≤ 10 ng/ml) and adequate (> 10 ng/ml) groups based on 25OH D levels on day 1. RESULTS: Mean ± SD maternal levels of 25OH D (21± 9 ng/ml) correlated with infants' levels (15 ± 8 ng/ml), (p< 0...
May 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28511836/corrigendum-to-morbidity-and-mortality-of-very-low-birth-weight-infants-in-taiwan-changes-in-15-years-a-population-based-study-j-formos-med-assoc-115-2016-1039-1045
#7
Yi-Yu Su, Shih-Hsin Wang, Hung-Chieh Chou, Chien-Yi Chen, Wu-Shiun Hsieh, Po-Nien Tsao, Kuo-Inn Tsou
No abstract text is available yet for this article.
June 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28499135/pain-threshold-tolerance-and-intensity-in-adolescents-born-very-preterm-or-with-low-birth-weight
#8
Christ-Jan J L M van Ganzewinkel, Jasper V Been, Inge Verbeek, Tera Boelen van der Loo, Sylvia M van der Pal, Boris W Kramer, Peter Andriessen
BACKGROUND: Data on long-term consequences of neonatal pain is limited. AIM: To assess whether perinatal factors, later pain experience and pain coping strategies are associated with altered pain threshold, pain tolerance and pain intensity in adolescents born preterm. STUDY DESIGN: Observational, longitudinal study (Project on Preterm and SGA-infants, POPS-19). SUBJECTS: We analyzed data of 412 adolescents at the age of 19years, who were born at a gestational age<32weeks or with a birth weight<1500g...
May 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/28498519/starting-enteral-nutrition-with-preterm-single-donor-milk-instead-of-formula-affects-time-to-full-enteral-feeding-in-very-low-birth-weight-infants
#9
Alexandra Kreissl, Elisabeth Sauerzapf, Andreas Repa, Christoph Binder, Margarita Thanhaeuser, Bernd Jilma, Robin Ristl, Angelika Berger, Nadja Haiden
AIM: This study compared the impact of using either single donor breast milk or formula to start enteral feeding in preterm infants, on the time to full enteral feeding, growth and morbidity. The milk was provided by other preterm mothers. METHODS: This was an observational prospective study, carried out from June 2012 - March 2013 at the Medical University of Vienna, Austria, on the effects of preterm single donor milk on 133 very low birth weight infants with a birth weight <1,500g and a gestational age <32 weeks until they were on full enteral feeding...
May 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28491927/iron-supplements-for-infants-at-risk-for-iron-deficiency
#10
Brianna C MacQueen, Vickie L Baer, Danielle M Scott, Con Yee Ling, Elizabeth A O'Brien, Caitlin Boyer, Erick Henry, Robert E Fleming, Robert D Christensen
Professional societies have published recommendations for iron dosing of preterm neonates, but differences exist between guidelines. To help develop standardized guidelines, we performed a 10-year analysis of iron dosing in groups at risk for iron deficiency: IDM (infants of diabetic mothers), SGA (small for gestational age), and VLBW premature neonates (very low birth weight, <1500 g). We analyzed iron dosing after red cell transfusions and erythropoiesis-stimulating agents (ESA). Of IDM, 11.8% received iron in the hospital; 9...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28480219/apolipoprotein-e-genotype-in-very-preterm-neonates-with-intrauterine-growth-restriction-an-analysis-of-the-german-neonatal-network-cohort
#11
Stephen Norda, Tanja K Rausch, Thorsten Orlikowsky, Matthias Hütten, Sören Schulz, Wolfgang Göpel, Ulrich Pecks
Aim. Cord blood of intrauterine growth restricted (IUGR) neonates displays lipid changes towards atherosclerotic profiles. Apolipoprotein E (ApoE) and its isoforms (e2, e3, and e4) are involved in the regulation of lipid metabolism. Specifically, ApoE e4 has been associated with atherosclerotic diseases, while e2 has a favorable effect. We therefore hypothesized that ApoE e4 haplotype is frequently observed in IUGR neonates and contributes to impaired fetal growth and the association of IUGR with cardiovascular and metabolic diseases later in life...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28477387/role-of-sex-in-morbidity-and-mortality-of-very-premature-neonates
#12
Masato Ito, Masanori Tamura, Fumihiko Namba
BACKGROUND: This study aimed to investigate the effect of sex on survival and short-term outcomes of very low birth weight infants (VLBWIs) born in Japan. METHODS: This study included VLBWIs who were admitted to neonatal intensive care units between 2003 and 2012 participating in the Neonatal Research Network of Japan. The primary outcome was a composite of mortality or any major morbidity, including neurologic injury, bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), or retinopathy of prematurity requiring treatment...
May 6, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28476473/decrease-in-delivery-room-intubation-rates-after-use-of-nasal-intermittent-positive-pressure-ventilation-in-the-delivery-room-for-resuscitation-of-very-low-birth-weight-infants
#13
Manoj Biniwale, Fiona Wertheimer
BACKGROUND: The literature supports minimizing duration of invasive ventilation to decrease lung injury in premature infants. Neonatal Resuscitation Program recommended use of non-invasive ventilation (NIV) in delivery room for infants requiring prolonged respiratory support. OBJECTIVE: To evaluate the impact of implementation of non-invasive ventilation (NIV) using nasal intermittent positive pressure ventilation (NIPPV) for resuscitation in very low birth infants...
May 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28472980/efficacy-and-safety-of-early-supplementation-with-800%C3%A2-iu-of-vitamin-d-in-very-preterm-infants-followed-by-underlying-levels-of-vitamin-d-at-birth
#14
Sang Yeun Cho, Hyun-Kyung Park, Hyun Ju Lee
BACKGROUND: To determine the efficacy and safety of early supplementation with 800 IU of vitamin D in very low birth weight (VLBW) infants. METHODS: Sixty-six infants with a birth weight less than 1500 g admitted to the Neonatal Intensive Care Unit. Of these, 52 infants were eligible and received 800 IU/day vitamin D from 2 weeks of age. We examined 25-hydroxyvitamin-D (25[OH]D) levels from cord blood at birth and serum at 32 and 36 weeks of postmenstrual age...
May 4, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28472859/lifestyle-interventions-for-the-treatment-of-women-with-gestational-diabetes
#15
REVIEW
Julie Brown, Nisreen A Alwan, Jane West, Stephen Brown, Christopher Jd McKinlay, Diane Farrar, Caroline A Crowther
BACKGROUND: Gestational diabetes (GDM) is glucose intolerance, first recognised in pregnancy and usually resolving after birth. GDM is associated with both short- and long-term adverse effects for the mother and her infant. Lifestyle interventions are the primary therapeutic strategy for many women with GDM. OBJECTIVES: To evaluate the effects of combined lifestyle interventions with or without pharmacotherapy in treating women with gestational diabetes. SEARCH METHODS: We searched the Pregnancy and Childbirth Group's Trials Register (14 May 2016), ClinicalTrials...
May 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28471478/probiotics-for-the-prevention-of-necrotizing-enterocolitis-in-very-low-birth-weight-infants-a-meta-analysis-and-systematic-review
#16
REVIEW
John P Thomas, Tim Raine, Sanath Reddy, Gusztav Belteki
We performed an updated meta-analysis incorporating the results of recent randomised controlled trials (RCTs) to measure the effectiveness of probiotic supplementation in preventing necrotizing enterocolitis (NEC) and death in very-low-birth-weight (VLBW) infants, and to investigate any differences in efficacy by probiotic agent. Using meta-regression analysis, we assessed the contribution of other measured variables on the overall effect size and between-study variability. CONCLUSION: Overall, probiotics lead to significant reductions in NEC incidence and mortality in VLBW infants...
May 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28470839/variation-in-term-birth-weight-across-european-countries-affects-the-prevalence-of-small-for-gestational-age-among-very-preterm-infants
#17
Jennifer Zeitlin, Anna-Karin Edstedt Bonamy, Aurelie Piedvache, Marina Cuttini, Henrique Barros, Patrick Van Reempts, Jan Mazela, Pierre-Henri Jarreau, Ludwig Gortner, Elizabeth S Draper, Rolf F Maier
AIM: This study assessed the prevalence of small for gestational age (SGA) among very preterm (VPT) infants using national and European intrauterine references. METHODS: We generated country-specific and common European intrauterine growth references for 11 European countries, according to Gardosi's approach and Hadlock's fetal growth model, by using national data on birth weights by sex. These references were applied to the Effective Perinatal Intensive Care in Europe (EPICE) cohort, which comprised 7,766 live VPT births without severe congenital anomalies under 32 weeks of gestation in 2011-12, to estimate the prevalence of infants with SGA birth weights, namely those below the 10th percentile...
May 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28459851/correction-mortality-and-length-of-stay-of-very-low-birth-weight-and-very-preterm-infants-a-eurohope-study
#18
Dino Numerato, Giovanni Fattore, Fabrizio Tediosi, Rinaldo Zanini, Mikko Peltola, Helen Banks, Péter Mihalicza, Liisa Lehtonen, Sofia Sveréus, Richard Heijink, Søren Toksvig Klitkou, Eilidh Fletcher, Amber A van der Heijden, Fredrik Lundberg, Eelco Over, Unto Häkkinen, Timo T Seppälä
[This corrects the article DOI: 10.1371/journal.pone.0131685.].
2017: PloS One
https://www.readbyqxmd.com/read/28454697/tissue-differences-in-dna-methylation-changes-at-ahrr-in-full-term-low-birth-weight-in-maternal-blood-placenta-and-cord-blood-in-chinese
#19
Fu-Ying Tian, Marie-France Hivert, Xiaozhong Wen, Chuanbo Xie, Zhongzheng Niu, Lijun Fan, Matthew W Gillman, Wei-Qing Chen
INTRODUCTION: Very few study addressed the relationship between Aryl-hydrocarbon receptor repressor (AHRR) DNA methylation and low birth weight, especially in multiple tissues of mother-infant pairs. In this study, we aimed to investigate AHRR DNA methylation modification in cord blood, placenta and maternal blood between full term low birth weight (FT-LBW) and full term normal birth weight (FT-NBW) newborns. METHODS: We enrolled 90 FT-LBW and 90 FT-NBW mother-infant pairs, of which all placenta and cord blood samples were collected while 45 maternal blood samples of each group were collected...
April 2017: Placenta
https://www.readbyqxmd.com/read/28443531/probiotics-to-prevent-necrotising-enterocolitis-and-nosocomial-infection-in-very-low-birth-weight-preterm-infants
#20
J Uberos, E Aguilera-Rodríguez, A Jerez-Calero, M Molina-Oya, A Molina-Carballo, E Narbona-López
The aim of the study was to determine whether routine probiotic supplementation (RPS) with Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus +Lactobacillus bifidum is associated with reduced risk of necrotising enterocolitis (NEC)≥Stage II in preterm neonates born at ≤32 weeks' gestation. We conducted a retrospective cohort study on the effect of probiotic supplementation in very low birth weight infants in our neonatal unit by comparing two periods: before and after supplementation. The incidence of NEC≥Stage II, late-onset sepsis and all-cause mortality was compared for an equal period 'before' (Period I) and 'after' (Period II) RPS with LGG or L...
April 26, 2017: British Journal of Nutrition
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