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Very low birth weight infant

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https://www.readbyqxmd.com/read/29145693/early-erythropoiesis-stimulating-agents-in-preterm-or-low-birth-weight-infants
#1
REVIEW
Arne Ohlsson, Sanjay M Aher
BACKGROUND: Preterm infants have low plasma levels of erythropoietin (EPO), providing a rationale for the use of erythropoiesis-stimulating agents (ESAs) to prevent or treat anaemia and to provide neuro protection and protection against necrotising enterocolitis (NEC). Darbepoetin (Darbe) and EPO are currently available ESAs. OBJECTIVES: To assess the effectiveness and safety of ESAs (erythropoietin (EPO) and/or Darbe) initiated early (before eight days after birth) compared with placebo or no intervention in reducing red blood cell (RBC) transfusions, adverse neurological outcomes, and feeding intolerance including necrotising enterocolitis (NEC) in preterm and/or low birth weight infants...
November 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29141590/health-nutrition-and-development-of-children-born-preterm-and-low-birth-weight-in-rural-rwanda-a-cross-sectional-study
#2
Catherine M Kirk, Jean Claude Uwamungu, Kim Wilson, Bethany L Hedt-Gauthier, Neo Tapela, Peter Niyigena, Christian Rusangwa, Merab Nyishime, Evrard Nahimana, Fulgence Nkikabahizi, Christine Mutaganzwa, Eric Ngabireyimana, Francis Mutabazi, Hema Magge
BACKGROUND: As care for preterm and low birth weight (LBW) infants improves in resource-limited settings, more infants are surviving the neonatal period. Preterm and (LBW) infants are at high-risk of nutritional and medical comorbidities, yet little is known about their developmental outcomes in low-income countries. This study evaluated the health, nutritional, and developmental status of preterm/LBW children at ages 1-3 years in Rwanda. METHODS: Cross-sectional study of preterm/LBW infants discharged between October 2011 and October 2013 from a hospital neonatal unit in rural Rwanda...
November 15, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29132733/enhanced-nutrient-supply-to-very-low-birth-weight-infants-is-associated-with-higher-blood-amino-acid-concentrations-and-improved-growth
#3
Kenneth Strømmen, Alexander Haag, Sissel J Moltu, Marit B Veierød, Elin W Blakstad, Britt Nakstad, Astrid N Almaas, Kristin Brække, Arild E Rønnestad, Hannelore Daniel, Christian A Drevon, Per O Iversen
BACKGROUND & AIMS: Customized nutrient supply is vital to ensure optimal growth among very low birth weight infants (birth weight < 1500 g). The supply of amino acids is especially important due to their impact on protein synthesis and growth. The objectives of this study were to evaluate the impact of enhanced nutrition on growth, blood concentrations of amino acids, and explore possible associations between amino acid concentrations and common neonatal morbidities. We hypothesized higher amino acids levels and growth velocity among infants on enhanced nutrient supply...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29132456/-incidence-of-late-onset-sepsis-in-very-low-birth-weight-and-extremely-low-birth-weight-infants-and-risk-factors-for-late-onset-sepsis
#4
Xiao-Peng Zhao, Wei Zhou, Xu-Fang Li, Yan-Yan Song, Ting-Yan Zhang, Hong Liang
OBJECTIVE: To investigate the incidence of late-onset sepsis (LOS) in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants in the neonatal intensive care unit (NICU) and the risk factors for LOS. METHODS: A retrospective analysis was performed for the clinical data of all VLBW and ELBW infants who were hospitalized in the NICU between January 2011 and December 2013. According to the presence or absence of LOS, these infants were divided into LOS group and non-LOS group...
November 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29132165/ivh-in-vlbw-preterm-babies-therapy-with-recombinant-activated-f-vii
#5
Matthias Knüpfer, Jenny Ritter, Ferdinand Pulzer, Corinna Gebauer, Nadine Wolf, Anett Bläser, Jens Dreyhaupt, Ulrich Thome
Backround Intraventricular hemorrhage (IVH) remains a dangerous and frequent complication in very low birth weight (VLBW) infants. Activated factor VII (aFVII) activates the coagulation cascade and is a potential tool for stopping active bleeding, including limiting the extent of an IVH. This retrospective treatment observation compared data for infants with IVH progression treated with fresh frozen plasma (FFP) alone or with a combination of FFP and aFVII. Methods/Intervention All infants were subject to cranial ultrasonography at least twice daily...
November 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29131125/splanchnic-cerebral-oxygenation-ratio-decreases-during-enteral-feedings-in-anemic-preterm-infants-observations-under-near-infrared-spectroscopy
#6
Katherine Braski, Kimberlee Weaver-Lewis, Manndi Loertscher, Qian Ding, Xiaoming Sheng, Mariana Baserga
BACKGROUND: Anemia is common in premature infants. Due to risks with red blood cell transfusions, many anemic infants are not transfused. The implications of this pathophysiologic status, especially at times of increased metabolic demand (enteral feedings), is not well understood. Near-infrared spectroscopy (NIRS) allows for the noninvasive determination of regional oxygen saturations (rSO2) in tissues such as the brain and mesentery, giving insight into their oxygen sufficiency. OBJECTIVE: We tested the hypothesis that during enteral feedings very low birth weight (VLBW) infants with a hematocrit ≤28% will experience a decrease in splanchnic rSO2 and splanchnic-cerebral oxygenation ratio (SCOR)...
November 8, 2017: Neonatology
https://www.readbyqxmd.com/read/29130703/nutritional-practices-in-very-low-birth-weight-infants-a-national-survey
#7
Miguel Sáenz de Pipaón, Ricardo Closa, María Gormaz, Marcos Linés, Eduardo Narbona, Gerardo Rodríguez-Martínez, José Uberos, Carlos Zozaya, María L Couce
BACKGROUND: Significant efforts have been made to improve the nutritional support of very preterm infants. Large surveys may help to know the nutritional practices for preterm infants in neonatal units and identify if they are in line with the current guidelines. METHODS: A multicentre nationwide web-based survey on clinical feeding practices in very low birth weight (VLBW) infants was conducted in tertiary neonatal hospitals that admit infants with a birth weight < 1,500 g and/or a gestational age of < 32 weeks...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29130702/-short-medium-and-long-term-benefits-of-human-milk-intake-in-very-low-birth-weight-infants
#8
Bibiana Chinea Jiménez, Yumana Awad Parada, Antonio Villarino Marín, Miguel Sáenz de Pipaón Marcos
AIM: The aim of the present study is to evaluate the effect of human milk feeding during the first weeks of life in very low birth weight infants on weight gain at discharge, length of hospitalization, postmenstrual age at discharge and nutritional assessment, growth and neurodevelopment at two and five years. MATERIAL AND METHODS: Longitudinal study of very-low-birth-weight infants (< 1,500 grams) admitted to the Neonatal Intensive Care Unit of La Paz University Hospital, from January 1st 2009 to December 31st 2009, followed in the follow-up clinic...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29122829/retrospective-cohort-analysis-on-pancreatic-enzyme-substitution-in-very-low-birthweight-infants-with-postnatal-growth-failure
#9
Julian O Ziegler, Christoph Maas, Wolfgang Bernhard, Joerg Arand, Christian F Poets, Axel R Franz
OBJECTIVE: To evaluate the effects of pancreatic enzyme substitution (PES) in selected very low birthweight (VLBW) infants with poor postnatal growth despite intensified nutritional support. DESIGN: Retrospective historic cohort study with matched controls. SETTING: Single level III neonatal intensive care unit. PATIENTS: Infants with a gestational age at birth <32 weeks and birth weight <1500 g born between 1 January 2005 and 31 December 2014 (n=26) who received PES for restricted postnatal growth despite intensified enteral nutritional support in comparison with infants matched for birth weight, birth year, gestational and postnatal age (n=52)...
November 9, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29120450/apnea-bradycardia-and-desaturation-spells-in-premature-infants-impact-of-a-protocol-for-the-duration-of-spell-free-observation-on-interprovider-variability-and-readmission-rates
#10
P Chandrasekharan, M Rawat, A M Reynolds, K Phillips, S Lakshminrusimha
OBJECTIVE: To study the impact of implementing a protocol to standardize the duration of observation in preterm infants with apnea/bradycardia/desaturation spells before hospital discharge on length of stay (LOS) and readmission rates. STUDY DESIGN: A protocol to standardize the duration of in-hospital observation for preterm infants with apnea, bradycardia and desaturation spells who were otherwise ready for discharge was implemented in December 2013. We evaluated the impact of this protocol on the LOS and readmission rates of very low birth weight infants (VLBW)...
November 9, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29119814/acceptability-and-feasibility-of-collecting-psychosocial-data-from-fathers-of-very-low-birth-weight-infants
#11
S R Bagge, B Westgate, K Few, P Clarke, A Adlam, J Walsh, M O'Brien
The aim of this study was to determine the feasibility and acceptability of collecting outcome data from parents of very low birth weight (VLBW) infants and to explore the psychological and social adaptation of fathers. Questionnaires were distributed to 38 parents of VLBW infants and 36 parents of term infants within a hospital Neonatal Intensive Care Unit. Field notes were also taken. Parents indicated collecting outcome data in this population was feasible and acceptable, but barriers and difficulties in data collection were identified, particularly for fathers...
September 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29119665/adults-who-were-born-preterm-with-a-very-low-birth-weight-reported-a-similar-health-related-quality-of-life-to-their-term-born-peers
#12
Johan Björkqvist, Petteri Hovi, Anu-Katriina Pesonen, Katri Räikkönen, Kati Heinonen, Anna-Liisa Järvenpää, Johan G Eriksson, Sture Andersson, Eero Kajantie
Approximately 1% of European infants are born preterm with a very low birth weight (VLBW) of less than 1,500g and the first babies born at the threshold of viability who received modern neonatal intensive care are now adults. While most live healthy lives, average VLBW adults tend to have more neurodevelopmental disabilities, lower educational achievement and higher rates of chronic conditions (1). Health-related quality of life (HRQoL) is defined as a construct of physical, mental and social wellbeing. This article is protected by copyright...
November 8, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29119215/surgical-ligation-versus-percutaneous-closure-of-patent-ductus-arteriosus-in-very-low-weight-preterm-infants-which-are-the-real-benefits-of-the-percutaneous-approach
#13
A Rodríguez Ogando, I Planelles Asensio, A Rodríguez Sánchez de la Blanca, F Ballesteros Tejerizo, M Sánchez Luna, J M Gil Jaurena, C Medrano López, J L Zunzunegui Martínez
Percutaneous treatment of patent ductus arteriosus (PDA) in extreme premature infants is technically difficult, and therefore, often not consider as an alternative to surgery. The main objective of our work was to compare respiratory status prior and post ductal closure and morbi-mortality, in our series of preterm infants with percutaneous PDA closure versus surgical ligation in the same time-period. Retrospective review of all premature infants submitted to percutaneous and surgical PDA closure from January 2011 to December 2016...
November 8, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29112088/serum-25-hydroxy-vitamin-d-levels-in-very-low-birth-weight-infants-receiving-oral-vitamin-d-supplementation
#14
Upender K Munshi, Pauline D Graziano, Kara Meunier, Jennifer Ludke, Angel Rios
BACKGROUND: Vitamin D supplementation in preterm infants has been recommended by American Academy of Pediatrics (AAP) however its efficacy and safety has not been well studied. OBJECTIVE: To study 25 hydroxy vitamin D (25OHD) levels as a marker of vitamin D status of very low birth weight infants while on vitamin D supplementation during NICU hospitalization. METHODS: Retrospective study of preterm infants with birth weight <1500 g admitted to our unit from Jan 2013 to Dec 2015 who were on oral Vitamin D3 400 IU supplementation...
November 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29108006/incidence-and-outcomes-of-acute-kidney-injury-in-extremely-low-birth-weight-infants
#15
Chien-Chung Lee, Oi-Wa Chan, Mei-Yin Lai, Kai-Hsiang Hsu, Tai-Wei Wu, Wai-Ho Lim, Yu-Cheng Wang, Reyin Lien
BACKGROUND: Acute kidney injury (AKI) is a common event in the neonatal intensive care unit (NICU), especially in extremely-low-birth-weight (ELBW) infants. This cohort study investigated the incidence of and risk factors for AKI in ELBW infants and their overall survival at the postmenstrual age (PMA) of 36 weeks. METHODS: All ELBW infants admitted to our NICU between January 2010 and December 2013 were enrolled. Those who died prior to 72 hours of life, had congenital renal abnormality, or had only one datum of the serum creatinine (SCr) level after the first 24 hours of life were excluded...
2017: PloS One
https://www.readbyqxmd.com/read/29107448/hope-in-parents-of-very-low-birth-weight-infants-and-its-association-with-parenting-stress-and-quality-of-life
#16
Trond Nordheim, Tone Rustøen, Anne Lee Solevåg, Milada Cvancarova Småstuen, Britt Nakstad
PURPOSE: Being a parent of a very-low-birth-weight (VLBW) infant can be stressful. We aimed to describe parental hope 42months after the birth of a VLBW infant and determine whether there is an association between hope and parenting stress with quality of life (QoL), respectively. DESIGN AND METHODS: Fifty-nine parents of VLBW infants completed questionnaires about hope, parenting stress and QoL. Pearson correlation coefficients (r) and linear regression models were used to examine the relationship between the selected variables...
October 26, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29104345/risk-factors-for-the-development-of-refeeding-syndrome-like-hypophosphatemia-in-very-low-birth-weight-infants
#17
Aiko Igarashi, Takashi Okuno, Genrei Ohta, Shuko Tokuriki, Yusei Ohshima
Background: Refeeding syndrome is characterized by metabolic disturbance including hypophosphatemia and hypokalemia upon reinstitution of nutrition in severely malnourished patients. Objective: The present study sought to identify the risk factors for the development of refeeding syndrome-like metabolic disturbance in very low birth weight infants. Methods: The correlations of severe hypophosphatemia with the serum levels of potassium and ionized calcium, daily calorie and phosphate intake, and umbilical cord blood flow on ultrasonography were analyzed in 49 very low birth weight infants...
2017: Disease Markers
https://www.readbyqxmd.com/read/29103210/insulin-for-the-treatment-of-women-with-gestational-diabetes
#18
REVIEW
Julie Brown, Luke Grzeskowiak, Kathryn Williamson, Michelle R Downie, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with short- and long-term complications for the mother and her infant. Women who are unable to maintain their blood glucose concentration within pre-specified treatment targets with diet and lifestyle interventions will require anti-diabetic pharmacological therapies. This review explores the safety and effectiveness of insulin compared with oral anti-diabetic pharmacological therapies, non-pharmacological interventions and insulin regimens...
November 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29095914/correction-does-visceral-osteopathic-treatment-accelerate-meconium-passage-in-very-low-birth-weight-infants-a-prospective-randomized-controlled-trial
#19
Nadja Haiden, Birgit Pimpel, Alexandra Kreissl, Bernd Jilma, Angelika Berger
[This corrects the article DOI: 10.1371/journal.pone.0123530.].
2017: PloS One
https://www.readbyqxmd.com/read/29095842/asymmetry-of-cerebral-glucose-metabolism-in-very-low-birth-weight-infants-without-structural-abnormalities
#20
Jae Hyun Park, Chun Soo Kim, Kyoung Sook Won, Jungsu S Oh, Jae Seung Kim, Hae Won Kim
METHODS: Thirty-six VLBW infants who underwent F-18 fluorodeoxyglucose (F-18 FDG) brain PET and MRI were prospectively enrolled, while infants with evidence of parenchymal brain injury on MRI were excluded. The regional glucose metabolic ratio and asymmetry index were calculated. The asymmetry index more than 10% (right > left asymmetry) or less than -10% (left > right asymmetry) were defined as abnormal. Regional cerebral glucose metabolism were compared between right and left cerebral hemispheres, and between the following subgroups: multiple gestations, premature rupture of membrane, bronchopulmonary dysplasia, and low-grade intraventricular hemorrhage...
2017: PloS One
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