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https://www.readbyqxmd.com/read/29771829/repairing-a-facial-cleft-by-polyether-ether-ketone-implant-combined-with-titanium-mesh
#1
Yuan Deng, Weiwei Tang, Zhengkang Li
The Tessier Number 4 cleft is one of the rarest, most complex craniofacial anomalies that presents difficulties in surgical treatment. In this article, we report a case of simultaneous facial depression, eye displacement, and medial canthus deformity. In this case, the maxillary bony defect was reconstructed using computer-assisted design computer-assisted manufacturing (CAD-CAM) polyether-ether-ketone (PEEK) material, and the orbital floor defect was repaired with AO prefabricated titanium mesh. Additionally, the medial canthus was modified with canthopexy and a single Z-plasty flap...
May 15, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29724578/does-severity-of-acetabular-dysplasia-influence-clinical-outcomes-after-periacetabular-osteotomy-a-case-control-study
#2
George Grammatopoulos, Paul E Beaulé, Cecilia Pascual-Garrido, Jeff J Nepple, John C Clohisy
BACKGROUND: Detailed characterization of factors influencing post-periacetabular osteotomy (PAO) outcome could guide treatment offered. METHODS: Using a prospective, multicenter database of PAOs, 61 hips/patients (51 females) with lesser dysplasia (acetabular index < 15° and lateral center-edge angle > 15°) were case-control matched for age, gender, body mass index, Tönnis grade, and joint congruency (P = .6-.9) with a "comparison group" of pronounced dysplasia (n = 183), aiming to assess whether severity of acetabular dysplasia has an effect on outcome following PAO and/or the ability to achieve desired acetabular correction...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29705672/mechanical-properties-of-cobalt-chromium-3-unit-fixed-dental-prostheses-fabricated-by-casting-milling-and-additive-manufacturing
#3
Marit Øilo, Harald Nesse, Odd Johan Lundberg, Nils Roar Gjerdet
STATEMENT OF PROBLEM: New additive manufacturing techniques for nonprecious alloys have made the fabrication of metal-ceramic fixed partial dentures (FPDs) less expensive and less time-consuming. However, whether the mechanical properties produced by these techniques are comparable is unclear. PURPOSE: The purpose of this in vitro study was to evaluate the mechanical properties of cobalt-chromium frameworks for FPDs fabricated by 3 different techniques. MATERIAL AND METHODS: Thirty frameworks for 3-unit FPDs were fabricated by traditional casting, computer-aided design and computer-aided manufacturing (CAD-CAM) milling, and selective laser melting (SLM), with n=10 in each group...
April 25, 2018: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29698301/is-there-an-association-between-borderline-to-mild-dysplasia-and-hip-osteoarthritis-analysis-of-ct-osteoabsorptiometry
#4
Tohru Irie, Daisuke Takahashi, Tsuyoshi Asano, Ryuta Arai, Muhammad Alaa Terkawi, Yoichi M Ito, Norimasa Iwasaki
BACKGROUND: The definitive treatment of borderline-to-mild dysplasia remains controversial. A more comprehensive understanding of the etiology of osteoarthritis (OA) and clarification of any possible association between borderline-to-mild dysplasia and the pathogenesis of OA are essential. QUESTIONS/PURPOSES: (1) Does the distribution of acetabular subchondral bone density increase according to dysplasia severity? (2) Is there an association between borderline-to-mild dysplasia and OA pathogenesis? METHODS: We evaluated bilateral hips of patients with developmental dysplasia of the hip who underwent eccentric rotational acetabular osteotomy (ERAO) for inclusion in the dysplasia group and contralateral hips of patients with unilateral idiopathic osteonecrosis of the femoral head (ONFH) who underwent curved intertrochanteric varus osteotomy (CVO) for the control group...
April 23, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29675516/biomechanical-effect-of-ferrule-on-incisors-restored-with-a-fiberglass-post-and-lithium-disilicate-ceramic-crown-after-thermal-cycling-and-fatigue-loading
#5
Andréa Dolores Correia Miranda Valdivia, Monise de Paula Rodrigues, Aline Aredes Bicalho, Bart Van Meerbeek, Jos Vander Sloten, Roberto Sales E Pessoa, Carlos José Soares
PURPOSE: To evaluate the biomechanics of endodontically treated incisors restored with a fiberglass post and a CAD/CAM lithium-disilicate ceramic crown with/without a ferrule after thermal and mechanical aging. MATERIALS AND METHODS: Twenty bovine incisors were divided into two groups (n = 10): 1. Fe, with a ferrule of 2 mm, and 2. NFe, without a ferrule. After endodontic treatment, the teeth were restored using a fiberglass post (Exacto 3, Angelus) and composite core (Tetric Ceram, Ivoclar Vivadent)...
April 19, 2018: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/29610778/testing-occlusal-performance-by-using-chewing-simulation-with-virtually-designed-substrate
#6
Andra Maria Pascale, Sebastian Ruge, Steffen Hauth, Bernd Kordaß, Lars Linsen
Physically accurate deformable models based on the finite element method (FEM) are being used for a wide range of applications, from entertainment to medicine. This article describes how we applied this method in the CAD/CAM area that is concerned with reconstructing 3D models of teeth. We simulated the process of mastication by employing a deformable model that represented the substrate, and a rigid model that represented the teeth. We extended a recent approach for substrate deformation by also modelling the fracture of the substrate by the mastication process...
2018: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/29575173/vascular-supply-of-the-femoral-head-in-sheep-implications-for-the-ovine-femoroacetabular-impingement-model
#7
Moritz Tannast, Nadja Wolfer, Michael K Ryan, Katja M Nuss, Brigitte von Rechenberg, Simon D Steppacher
Sheep hips have a natural non-spherical head similar to a cam-type deformity in human beings. By performing an intertrochanteric varus osteotomy, cam-type femoroacetabular impingement can be induced experimentally. In sheep, the aspherical portion is located superiorly-exactly matching the region where the superior retinacular vessels enter the femoral head-neck junction in human beings. In order to fully exploit the potential of this experimental FAI model, a safe osteochondroplasty of the superior asphericity would need to be done without the risk of avascular necrosis...
March 25, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29567528/nano-scale-mechanical-behavior-of-pre-crystallized-cad-cam-zirconia-reinforced-lithium-silicate-glass-ceramic
#8
Gabriella A C Springall, Ling Yin
This paper reports on the mechanical behavior of pre-crystallized CAD/CAM zirconia-reinforced lithium silicate glass ceramic (ZLS) using nanoindentation with a Berkovich diamond tip and in situ scanning probe microscopy (SPM). The indentation contact hardness, the elastic modulus, and the elasticity and plasticity of the material were determined using the Oliver-Pharr method, the Sakai model and the Meyer's law at peak loads of 2.5-10 mN and a loading rate of 0.5 mN/s. The load-displacement curves at all applied loads indicate that ZLS deformed plastically without fracture...
March 9, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29564291/prevalence-of-cam-deformity-with-associated-femoroacetabular-impingement-syndrome-in-hip-joint-computed-tomography-of-asymptomatic-adults
#9
Jun Han, Seok-Hyung Won, Jung-Taek Kim, Myung-Hoon Hahn, Ye-Yeon Won
Purpose: Femoroacetabular impingement (FAI) is considered an important cause of early degenerative arthritis development. Although three-dimensional (3D) imaging such as computed tomography (CT) and magnetic resonance imaging are considered precise imaging modalities for 3D morphology of FAI, they are associated with several limitations when used in out-patient clinics. The paucity of FAI morphologic data in Koreans makes it difficult to select the most effective radiographical method when screening for general orthopedic problems...
March 2018: Hip & Pelvis
https://www.readbyqxmd.com/read/29554551/patient-specific-parameterised-cam-geometry-in-finite-element-models-of-femoroacetabular-impingement-of-the-hip
#10
Robert J Cooper, Sophie Williams, Marlène Mengoni, Alison C Jones
BACKGROUND: Impingement resulting in soft tissue damage has been observed in hips with abnormal morphologies. Geometric parameterisation can be used to automatically generate a range of bone geometries for use in computational models, including femurs with cam deformity on the femoral neck. METHODS: This study verified patient-specific parametric finite element models of 20 patients with cam deformity (10 female, 10 male) through comparison to their patient-specific segmentation-based equivalents...
March 14, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29537957/beyond-the-scope-open-treatment-of-femoroacetabular-impingement
#11
Michael K Ryan, Thomas Youm, Jonathan M Vigdorchik
Hip arthroscopy as we know it today developed over the last 15 to 20 years, yet its true beginning is far more dated. Initially developed as a means of removing loose bodies or as a means of lavage, hip arthroscopy was not utilized to treat femoroacetabular impingement (FAI) until much later. Its usefulness as a means of treating FAI did not arise until hip impingement was understood to be causal in the development of degenerative changes of the labrum and articular surfaces. As our understanding of FAI grew, the tools for treating it developed in tandem...
March 2018: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/29524520/the-tumor-antagonistic-steroidal-alkaloid-solanidine-prompts-the-intrinsic-suicidal-signal-mediated-dff-40-nuclear-import-and-nucleosomal-disruption
#12
Vikas H Malojirao, V Vigneshwaran, Prabhu Thirusangu, Riaz Mahmood, B T Prabhakar
Aim Deformity in the cellular homeostatic event associated with cell survival and apoptosis are committing factors for carcinogenesis. Interventions of these events by pharmacologically active agent gain predominance in cancer treatment. In current investigation Solanidine, a steroidal alkaloid was evaluated on tumorigenesis by targeting death signal using multiple tumor cells and model systems. MAIN METHODS: Anti-proliferative effect was evaluated using cytotoxic studies. Prolonged cytotoxic effect of Solanidine was examined by colony formation assay...
April 15, 2018: Life Sciences
https://www.readbyqxmd.com/read/29517923/anatomic-predictors-of-sagittal-hip-and-pelvic-motions-in-patients-with-a-cam-deformity
#13
K C Geoffrey Ng, Mario Lamontagne, Jonathan R T Jeffers, George Grammatopoulos, Paul E Beaulé
BACKGROUND: As there is a high prevalence of patients with cam deformities and no ongoing hip dysfunction, understanding the biomechanical factors predicting the onset of symptoms and degenerative changes is critical. One such variable is how the spinopelvic parameters may influence hip and pelvic sagittal mobility. Hypothesis/Purpose: Pelvic incidence may predict sagittal hip and pelvic motions during walking and squatting. The purpose was to determine which anatomic characteristics were associated with symptoms and how they influenced functional hip and pelvic ranges of motion (ROMs) during walking and squatting...
May 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29481345/morphologic-features-of-the-contralateral-femur-in-patients-with-unilateral-slipped-capital-femoral-epiphysis-resembles-mild-slip-deformity-a-matched-cohort-study
#14
Tobias Hesper, Sarah D Bixby, Daniel A Maranho, Patricia Miller, Young-Jo Kim, Eduardo N Novais
BACKGROUND: Hip osteoarthritis has been reported in the contralateral hip in patients who had been treated for unilateral slipped capital femoral epiphysis (SCFE) during adolescence. Although this might be related to the presence of a mild deformity, the morphologic features of the contralateral hip in unilateral SCFE remains poorly characterized. QUESTIONS/PURPOSES: Do measurements of (1) femoral head-neck concavity (α angle and femoral head-neck offset), (2) epiphyseal extension into the metaphysis (epiphyseal extension ratio and epiphyseal angle), and (3) posterior tilt of the epiphysis (epiphyseal tilt angle) differ between the contralateral asymptomatic hips of patients treated for unilateral SCFE and hips of an age- and sex-matched control population without a history of hip disease? METHODS: From January 2005 to May 2015, 442 patients underwent surgical treatment for SCFE at our institution...
April 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29475157/the-role-of-the-n-terminal-domain-of-human-apurinic-apyrimidinic-endonuclease-1-ape1-in-dna-glycosylase-stimulation
#15
Olga A Kladova, Milena Bazlekowa-Karaban, Sonia Baconnais, Olivier Piétrement, Alexander A Ishchenko, Bakhyt T Matkarimov, Danila A Iakovlev, Andrey Vasenko, Olga S Fedorova, Eric Le Cam, Barbara Tudek, Nikita A Kuznetsov, Murat Saparbaev
The base excision repair (BER) pathway consists of sequential action of DNA glycosylase and apurinic/apyrimidinic (AP) endonuclease necessary to remove a damaged base and generate a single-strand break in duplex DNA. Human multifunctional AP endonuclease 1 (APE1, a.k.a. APEX1, HAP-1, or Ref-1) plays essential roles in BER by acting downstream of DNA glycosylases to incise a DNA duplex at AP sites and remove 3'-blocking sugar moieties at DNA strand breaks. Human 8-oxoguanine-DNA glycosylase (OGG1), methyl-CpG-binding domain 4 (MBD4, a...
April 2018: DNA Repair
https://www.readbyqxmd.com/read/29441427/isolated-focal-cartilage-and-labral-defects-in-patients-with-femoroacetabular-impingement-syndrome-may-represent-new-unique-injury-patterns
#16
Ashley L Kapron, Stephen K Aoki, Jeffrey A Weiss, Aaron J Krych, Travis G Maak
PURPOSE: Develop a framework to quantify the size, location and severity of femoral and acetabular-sided cartilage and labral damage observed in patients undergoing hip arthroscopy, and generate a database of individual defect parameters to facilitate future research and treatment efforts. METHODS: The size, location, and severity of cartilage and labral damage were prospectively collected using a custom, standardized post-operative template for 100 consecutive patients with femoroacetabular impingement syndrome...
February 13, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29429067/hip-malformation-is-a-very-common-finding-in-young-patients-scheduled-for-total-hip-arthroplasty
#17
Dennis Karimi, Thomas Kallemose, Anders Troelsen, Jakob Klit
INTRODUCTION: In Denmark, 20% of all registered total hip arthroplasties (THA) from 1995 to 2014 has been patients younger than 60 years with primary idiopathic osteoarthritis (OA). It is speculated that hip malformations may be a major contributor to early OA development. It has been shown that hip malformation may compromise implant position and, therefore, identifying and knowing the incidence of malformations is important. Our aim was to assess the prevalence and type of hip malformations in a cohort of younger patients undergoing THA...
April 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29426842/molecular-channel-driven-actuator-with-considerations-for-multiple-configurations-and-color-switching
#18
Jiuke Mu, Gang Wang, Hongping Yan, Huayu Li, Xuemin Wang, Enlai Gao, Chengyi Hou, Anh Thi Cam Pham, Lianjun Wu, Qinghong Zhang, Yaogang Li, Zhiping Xu, Yang Guo, Elsa Reichmanis, Hongzhi Wang, Meifang Zhu
The ability to achieve simultaneous intrinsic deformation with fast response in commercially available materials that can safely contact skin continues to be an unresolved challenge for artificial actuating materials. Rather than using a microporous structure, here we show an ambient-driven actuator that takes advantage of inherent nanoscale molecular channels within a commercial perfluorosulfonic acid ionomer (PFSA) film, fabricated by simple solution processing to realize a rapid response, self-adaptive, and exceptionally stable actuation...
February 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29426010/persisting-cam-deformity-is-associated-with-early-cartilage-degeneration-after-slipped-capital-femoral-epiphysis-11-year-follow-up-including-dgemric
#19
J Örtegren, P Peterson, J Svensson, C J Tiderius
OBJECTIVE: Slipped capital femoral epiphysis (SCFE) in adolescence is associated with increased risk of future osteoarthritis (OA). The purpose of this study was to study clinical and radiographic risk factors for early cartilage degeneration after SCFE. DESIGN: 22 patients (44 hips) (mean age 24 years, range 18-27) treated with in situ fixation (The Hansson hook-pin) for stable SCFE on average 11 years previously were investigated. Cartilage status was assessed with delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC)...
April 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29423251/outcomes-of-intra-articular-corticosteroid-injections-for-adolescents-with-hip-pain
#20
Jennifer Tangtiphaiboontana, Alan L Zhang, Nirav K Pandya
Intra-articular injection of corticosteroid and anesthetic (CSI) is a useful diagnostic tool for hip pain secondary to labral tears or femoroacetabular impingement (FAI). However, the effectiveness of CSI as a stand-alone treatment for hip pain in adolescents is unknown. The purpose of this study is to evaluate the use of CSI for the treatment of hip pain and determine factors that may affect outcomes after injection. Retrospective analysis of 18 patients and 19 hips that underwent fluoroscopic guided hip injection for the treatment of pain at a single institution from 2012 to 2015 was carried out in this study...
January 2018: Journal of Hip Preservation Surgery
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