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https://www.readbyqxmd.com/read/27915249/new-and-highly-active-microbial-phosphotriesterase-sources
#1
Julia Y Santillan, Lucas A Dettorre, Elizabeth S Lewkowicz, Adolfo M Iribarren
Many toxic insecticides used worldwide as well as some chemical warfare agents are phosphotriester derivatives. Therefore, detoxification of organophosphorus compounds has become the subject of many studies and in particular bioremediation, based on the phosphotriesterase catalysed hydrolysis of these compounds, has shown to be an effective and ecological methodology. In order to identify new bacterial phosphotriesterases, a simple and sensitive fluorimetric screening method on solid media was employed, that allowed the selection of 6 strains with phosphotriesterase activity...
December 2, 2016: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/27904882/first-case-of-actinomycetoma-in-france-due-to-a-novel-nocardia-species-nocardia-boironii-sp-nov
#2
Jacques M Gilquin, Brigitte Riviere, Valme Jurado, Bernard Audouy, Jean-Baptiste Kouatche, Emmanuelle Bergeron, Delphine Mouniée, Thierry Molina, Philippe Faure, Cesáreo Saiz-Jimenez, Verónica Rodríguez-Nava
Bacterial mycetoma is a neglected disease mainly observed in tropical area countries and typically associated with rural conditions, making its presence in developed countries of temperate climate areas rare. However, we report the first case of an autochthonous mycetoma case in continental France that originated from a new Nocardia species. A Gram-positive filamentous bacterium (OFN 14.177(T)) was isolated from a pus sample from the mycetoma of a male French patient 92 years old suffering from chronic lymphocytic leukemia...
November 2016: MSphere
https://www.readbyqxmd.com/read/27904816/an-unusual-presentation-of-nocardiosis-in-an-allogeneic-transplant-recipient
#3
Uroosa Ibrahim, Amina Saqib, Farhan Mohammad, Terenig Terjanian
Nocardiosis is a rare cause of opportunistic infection post hematopoietic stem cell transplant (HSCT) occurring in about 0.3% of patients. The risk factors include delayed immune reconstitution, prolonged neutropenia, and graft-versus-host disease. The most common site of infection is the lung, followed by the brain and the skin. Concomitant pulmonary and central nervous system (CNS) nocardiosis is an extremely rare entity as presented in our case. We present the case of a 72-year-old male at 137 days post transplant presenting with complaints of headache and slurred speech...
October 17, 2016: Curēus
https://www.readbyqxmd.com/read/27882322/identification-of-species-of-nontuberculous-mycobacteria-clinical-isolates-from-8-provinces-of-china
#4
Haican Liu, Lulu Lian, Yi Jiang, Mingxiang Huang, Yunhong Tan, Xiuqin Zhao, Jingrui Zhang, Qin Yu, Jiao Liu, Haiyan Dong, Bing Lu, Yimou Wu, Kanglin Wan
Pulmonary diseases caused by nontuberculous mycobacteria (NTM) are increasing in incidence and prevalence worldwide. In this study, we identified NTM species of the clinical isolates from 8 provinces in China, in order to preliminarily provide some basic scientific data in the different species and distribution of NTM related to pulmonary disease in China. A total of 523 clinical isolates from patients with tuberculosis (TB) diagnosed clinically from 2005 to 2012 were identified to the species using conventional and molecular methods, including multilocus PCR, rpoB and hsp65 PCR-PRA, hsp65, rpoB, and 16S-23S internal transcribed spacer region sequencing...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27882160/disseminated-nocardiosis-caused-by-nocardia-otitidiscaviarum-in-an-immunocompetent-host-a-case-report-and-literature-review
#5
Yanwen Jiang, Aiben Huang, Qiuhong Fang
The aim of the present study was to summarize the clinical characteristics of nocardiosis caused by Nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. A case of dissemination nocardiosis caused by N. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed. Informed consent for publication of this case report was provided by the patient. The present patient was a young immunocompetent man suffering from disseminated nocardiosis induced by infection with N...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27872648/a-58-year-old-female-with-progressive-cough-and-right-shoulder-pain
#6
Sanket R Thakore, Faisal A Khasawneh
Cavitary pneumonia in immunocompromised patients is a challenging entity. Establishing accurate diagnosis and starting effective antibiotics are essential steps towards improving outcome. A 58-year-old stem cell transplant patient was admitted to the hospital with necrotizing pneumonia caused by nocardia. The disease progressed despite of aggrieve antimicrobial therapy. Nocardiosis continues to be a difficult disease to diagnose and treat.
2016: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/27865306/nocardia-bacteremia-and-endocarditis-in-a-patient-with-a-sulfa-allergy
#7
Jennifer Kuretski, Vishal Dahya, Lisa Cason, Prasad Chalasani, Moti Ramgopal
No abstract text is available yet for this article.
November 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27865245/adolescent-with-recurrent-tuberculosis-can-it-be-chronic-granulomatous-disease
#8
Yashashree Gupta, Ira Shah
Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency disorder with recurrent bacterial and fungal infections like Staphylococcus aureus, Nocardia spp, Serratia marcescens, Burkholderia cepacia, Salmonella spp. and Aspergillus species. We present a 13-year-old male child who had 3 episodes of tuberculosis (TB) at 5 years, 8 years and 13 years of age, respectively, with no other intercurrent infections and who was diagnosed as CGD at the age of 13 years. This case highlights the possibility of phenotypic variations of CGD...
July 2016: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/27861348/central-nervous-system-nocardiosis-in-queensland-a-report-of-20-cases-and-review-of-the-literature
#9
Nastaran Rafiei, Anna Maria Peri, Elda Righi, Patrick Harris, David L Paterson
Nocardia infection of the central nervous system (CNS) is an uncommon but clinically important disease, often occurring in immunocompromised individuals and carrying a high mortality rate. We present 20 cases of microbiologically proven CNS nocardiosis diagnosed in Queensland from 1997 to 2015 and review the literature from 1997 to 2016.Over 50% of cases occurred in immunocompromised individuals, with corticosteroid use posing a particularly significant risk factor. Nine (45%) patients were immunocompetent and 3 had no comorbidities at time of diagnosis...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27851424/1789-a-rare-case-of-nocardia-cardiac-device-infection-with-associated-bacteremia
#10
April Downey, Joseph Gastaldo
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27845850/ct-guided-percutaneous-lung-biopsies-in-patients-with-suspicion-for-infection-may-yield-clinically-useful-information
#11
Brian M Haas, Joshua D Clayton, Brett M Elicker, Karen G Ordovas, David M Naeger
OBJECTIVE: The objective of our study was to assess the frequency and time frame with which CT-guided lung biopsies for suspected infection yield information that can affect patient management. MATERIALS AND METHODS: All CT-guided lung biopsies over a 68-month period performed for the purpose of diagnosing a suspected infection were reviewed to determine the proportion that yielded information affecting patient management. Patients were included if infection was the only consideration causing the pulmonary lesion in question...
November 15, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27826114/nocardia-elegans-infection-a-case-report-and-literature-review
#12
REVIEW
Itaru Nakamura, Tomoki Nagakura, Hiroaki Fujita, Shinji Fukusima, Tohru Gonoi
A case of disseminated nocardiosis caused by Nocardia elegans in a 72-year-old man with rheumatoid arthritis, treated with tacrolimus and prednisolone, is reported herein. The patient had impaired vision and was diagnosed with endophthalmitis and an abdominal skin abscess. He was started on trimethoprim-sulfamethoxazole treatment, followed by cefepime. The patient was then switched to a combination of imipenem-cilastatin and minocycline. Although the patient survived as a result of surgery and prolonged antibiotic treatment, he eventually lost vision after the infection became resistant to antibiotic treatment...
November 5, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27802877/routine-identification-of-nocardia-species-by-maldi-tof-mass-spectrometry
#13
Victoria Girard, Sandrine Mailler, Sophie Polsinelli, Delphine Jacob, Marie Christine Saccomani, Beatrice Celliere, Valerie Monnin, Alex van Belkum, Ferry Hagen, Jacques F Meis, Géraldine Durand
We here show adequate species identification for bacterial isolates of the genus Nocardia spp. through VITEK mass spectrometry. Application of a specific sample preparation method in combination with a robust matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) database leads to 94% accurate identification to the species level on a set of 164 isolates. The possibility to identify Nocardia spp. using MALDI-TOF MS will be available in the next release of VITEK MS update (IVD Version 3...
January 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27794456/infections-of-the-central-nervous-system-following-unrelated-donor-umbilical-cord-blood-transplantation-or-hla-matched-sibling-transplantation
#14
Aitana Balaguer, Luis Bataller, Ignacio Lorenzo, Isidro Jarque, Miguel Salavert, Eva González, José Luis Piñana, Teresa Sevilla, Pau Montesinos, Gloria Iacoboni, Nuria Muelas, Samuel Romero, Carlos Carretero, Juan Montoro, Maria Jose Ibáñez-Juliá, Guillermo Sanz, Miguel Ángel Sanz, Jaime Sanz
We analyzed the incidence, clinical characteristics, prognostic factors and outcome of CNS infections in consecutive patients with receiving umbilical cord blood transplantation (UCBT) (n = 343) or HLA-matched sibling donor stem cell transplantation (MST) (n = 366). Thirty-four CNS infections were documented at a median time of 116 days after transplant (range, 7-1161). The cumulative incidence (CI) risk of developing a CNS infection was 0.6% at day +30, 2.3% at day +90 and 4.9% at 5 years. The 5-year CI of CNS infection was 8...
October 26, 2016: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27794389/activation-and-il-1%C3%AE-secretion-of-human-peripheral-phagocytes-infected-with-actinomadura-madurae-nocardia-asteroides-and-candida-albicans
#15
Alejandro Palma-Ramos, Gilberto Casillas-Pétriz, Laura Estela Castrillón-Rivera, Jorge Ismael Castañeda-Sánchez, Roberto Arenas-Guzmán, Maria Elisa Drago-Serrano, Teresita Sainz-Espuñes
OBJECTIVE: To evaluate the ability of Actinomadura madurae (A. madurae) and Nocardia asteroides (N. asteroides), using Candida albicans (C. albicans) as prototypic control, to elicit the activation and IL-1β secretion of blood phagocytic cells from healthy donors. METHODS: Microscopic evaluation of phagocytosis/activation, cell viability and spectrophotometric quantitation of endocytosis/activation, were assessed by using formazan blue test in human blood phagocytes infected with C...
October 2016: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27792951/amplicon-based-taxonomic-characterization-of-bacteria-in-urban-and-peri-urban-roof-harvested-rainwater-stored-in-tanks
#16
W Ahmed, C Staley, K A Hamilton, D J Beale, M J Sadowsky, S Toze, C N Haas
Overall, 26% of Australian households use rainwater tanks as a source of potable and nonpotable water. Limited information is available on the total bacterial communities in tank water. Therefore, identification of dominant bacterial communities, diversity, and their distribution is important in understanding the microbial quality of tank water. In this study, the abundance and diversity of bacterial communities in 88 tank water samples collected from the urban areas of Brisbane (n=44) and the peri-urban center of Currumbin (n=44) in Southeast Queensland, Australia were determined using amplicon-based Illumina next-generation sequencing...
October 25, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27774152/first-case-of-isolation-of-nocardia-wallacei-reported-in-mexico
#17
J González-Nava, K Sánchez-Herrera, N Ramírez-Durán, H Sandoval
Nocardia species are aerobic, Gram-positive bacteria with branched filaments reported as opportunistic microorganisms associated with infectious diseases of the skin. We report the isolation of N. wallacei in Mexico from a 43-year-old man, an HIV-positive construction worker who sought care for difficulty breathing and abundant sputum.
November 2016: New Microbes and New Infections
https://www.readbyqxmd.com/read/27766680/molecular-identification-of-unusual-mycetoma-agents-isolated-from-patients-in-venezuela
#18
Olga C Rojas, Rafael B R León-Cachón, Maria Moreno-Treviño, Gloria M González
Mycetoma is a chronic granulomatous, subcutaneous disease endemic in tropical and subtropical countries. It is currently a health problem in rural areas of Africa, Asia and South America. Nine cases of mycetoma were analysed in a retrospective study. All isolates were identified by morphological features. The level of species identification was reached by molecular tools. Definitive identification of fungi was performed using sequence analysis of the ITS of the ribosomal DNA region and the ribosomal large-subunit D1/D2...
October 21, 2016: Mycoses
https://www.readbyqxmd.com/read/27762425/haloalkalitolerant-actinobacteria-with-capacity-for-anthracene-degradation-isolated-from-soils-close-to-areas-with-oil-activity-in-the-state-of-veracruz-mexico
#19
Reyna Del C Lara-Severino, Miguel A Camacho-López, Edgar Casanova-González, Leobardo M Gómez-Oliván, Ángel H Sandoval-Trujillo, Keila Isaac-Olivé, Ninfa Ramírez-Durán
The use of native strains of microorganisms from soils is an excellent option for bioremediation. To our knowledge, until now there has been no other group working on the isolation of Actinobacteria from contaminated soils in Mexico. In this study, samples of soils close to areas with oil activity in the State of Veracruz, Mexico, were inoculated for the isolation of Actinobacteria. The strains isolated were characterized morphologically, and the concentrations of NaCl and pH were determined for optimal growth...
March 2016: International Microbiology: the Official Journal of the Spanish Society for Microbiology
https://www.readbyqxmd.com/read/27755185/anticytokine-autoantibodies-in-infection-and-inflammation-an-update
#20
Gabriela Barcenas-Morales, Peter Jandus, Rainer Döffinger
PURPOSE OF REVIEW: Concise overview of the field of anticytokine autoantibodies with a focus on recent developments. RECENT FINDINGS: Advances in particular in the analysis of autoantibodies to IFNγ, granulocyte-macrophage colony-stimulating factor (GM-CSF) and type I IFN are presented. The target epitope for anti-IFNγ autoantibodies has been found to have high homology to a protein from Aspergillus suggesting molecular mimicry as a mechanism of breaking self-tolerance...
December 2016: Current Opinion in Allergy and Clinical Immunology
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