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https://www.readbyqxmd.com/read/28445365/improvement-of-flap-necrosis-in-a-rat-random-skin-flap-model-by-in-vivo-electroporation-mediated-hgf-gene-transfer
#1
S Morteza Seyed Jafari, Maziar Shafighi, Helmut Beltraminelli, Thomas Geiser, Robert E Hunger, Amiq Gazdhar
BACKGROUND: Despite great understanding of underlying mechanisms for flap necrosis and advances in surgical techniques, flap necrosis remains a critical issue. In the present study, the authors investigated the efficacy of electroporation-mediated hepatocyte growth factor (HGF) gene delivery to random dorsal skin flaps (McFarlane) to accelerate wound healing and reduce flap necrosis. METHODS: Fifteen male Wistar rats (290 to 320 g) were divided randomly into three groups...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28436331/lep-expression-and-its-role-in-obesity-and-type-2-diabetes
#2
Muhammad Imran Qadir, Zara Ahmed
Obesity is metabolic disorder that increases the risk of diabetes, heart disease, and other metabolic syndromes in human beings. One sign of diabetes is increased blood glucose levels in the body. Glucose levels increase due to problems with insulin secretion or insulin resistance. Maturity onset of diabetes of the young is more common in adults and occurs due to insulin resistance. Both diabetes and obesity are major problems that are responsible for the death of millions of individuals every year, worldwide...
2017: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/28431559/effects-of-whole-grain-rye-with-and-without-resistant-starch-type-2-supplementation-on-glucose-tolerance-gut-hormones-inflammation-and-appetite-regulation-in-an-11-14-5%C3%A2-hour-perspective-a-randomized-controlled-study-in-healthy-subjects
#3
Jonna C Sandberg, Inger M E Björck, Anne C Nilsson
BACKGROUND: The prevalence of obesity is increasing worldwide and prevention is needed. Whole grain has shown potential to lower the risk of obesity, cardiovascular disease and type 2 diabetes. One possible mechanism behind the benefits of whole grain is the gut fermentation of dietary fiber (DF), e.g. non-starch polysaccharides and resistant starch (RS), in whole grain. The purpose of the study is to investigate the effect of whole grain rye-based products on glucose- and appetite regulation...
April 21, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28428150/satiety-regulation-in-children-with-loss-of-control-eating-and-attention-deficit-hyperactivity-disorder-a-test-meal-study
#4
Susanne Kurz, Dominik Schoebi, Daniela Dremmel, Wieland Kiess, Simone Munsch, Anja Hilbert
Children with loss of control (LOC) eating and attention-deficit/hyperactivity disorder (ADHD) are at risk for excessive weight gain. However, it is unclear whether or not these children show disturbances in hunger and satiety regulation. The goal was to examine the food intake and sense of LOC over eating as well as LOC eating-related characteristics during test meal in children with LOC eating and ADHD. Children aged 8-13 y with LOC eating (n = 33), ADHD (n = 32), and matched healthy controls (n = 33), consumed a test meal consisting of their chosen lunch food, with the instruction to eat until feeling full...
April 18, 2017: Appetite
https://www.readbyqxmd.com/read/28415967/chewing-gum-for-intestinal-function-recovery-after-caesarean-section-a-systematic-review-and-meta-analysis
#5
Zunjia Wen, Meifen Shen, Chao Wu, Jianping Ding, Binbin Mei
BACKGROUND: Gum chewing has been reported to enhance the intestinal function recovery after caesarean section, current perspectives and practice guidelines vary widely on the use of gum chewing, more studies on the role of gum chewing after caesarean section are needed. METHODS: We performed a comprehensive, systematic meta-analysis of randomized controlled trials (RCTs) on the efficacy of gum chewing after caesarean section. Studies were identified by searching EMBASE et al database (until June 30, 2016)...
April 18, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28414018/psychological-flexibility-mediates-change-in-intuitive-eating-regulation-in-acceptance-and-commitment-therapy-interventions
#6
Essi Sairanen, Asko Tolvanen, Leila Karhunen, Marjukka Kolehmainen, Elina Järvelä-Reijonen, Sanni Lindroos, Katri Peuhkuri, Riitta Korpela, Miikka Ermes, Elina Mattila, Raimo Lappalainen
OBJECTIVE: Despite the promising results related to intuitive eating, few studies have attempted to explain the processes encouraging this adaptive eating behaviour. The focus of the present study was on exploring mechanisms of change in intuitive eating and weight in acceptance and commitment therapy (ACT) interventions. Mediation provides important information regarding the treatment processes and theoretical models related to specific treatment approaches. The study investigates whether psychological flexibility, mindfulness skills and sense of coherence mediated the interventions' effect on intuitive eating and weight...
April 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28413912/the-acute-effects-of-baobab-fruit-adansonia-digitata-on-satiety-in-healthy-adults
#7
Rebecca Garvey, Miriam Clegg, Shelly Coe
BACKGROUND: The baobab fruit is high in both dietary fibre and polyphenols and therefore may increase satiety. The aim of the study was to measure the effects of baobab fruit extract on satiety. METHODS: The study was conducted on 20 healthy participants. The study was a one-day single-blind crossover design. Participants were randomised to either a test smoothie consisting of 15 g of baobab extract or a control smoothie without the addition of baobab. Subjective ratings of satiety were taken on visual analogue scales immediately pre-consumption and then post-consumption, and energy intake at a post ad libitum meal was recorded...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28405814/effects-of-coconut-oil-consumption-on-energy-metabolism-cardiometabolic-risk-markers-and-appetitive-responses-in-women-with-excess-body-fat
#8
Flávia Xavier Valente, Flávia Galvão Cândido, Lílian Lelis Lopes, Desirrê Morais Dias, Samantha Dalbosco Lins Carvalho, Patrícia Feliciano Pereira, Josefina Bressan
PURPOSE: Virgin coconut oil (VCO) is a medium-chain fatty acid source with popularly attributed benefits on obesity management. However, its role on obesity requires elucidation due to its saturated nature. In the study herein, we investigated acute effects of VCO consumption on energy metabolism, cardiometabolic risk markers, and appetitive responses in women with excess body fat. METHODS: Fifteen adult women with excess body fat (37.43 ± 0.83%) participated in this randomized, crossover, controlled study...
April 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28403206/persistent-weight-loss-with-a-non-invasive-novel-medical-device-to-change-eating-behaviour-in-obese-individuals-with-high-risk-cardiovascular-risk-profile
#9
Peter von Seck, F Martin Sander, Leon Lanzendorf, Sabine von Seck, André Schmidt-Lucke, Mirja Zielonka, Caroline Schmidt-Lucke
In evidence-based weight-loss programs weight regain is common after an initial weight reduction. Eating slowly significantly lowers meal energy intake and hunger ratings. Despite this knowledge, obese individuals do not implement this behaviour. We, thus tested the hypothesis of changing eating behaviour with an intra-oral medical device leading to constant weight reduction in overweight and obesity. Six obese patients (6 men, age 56 ± 14, BMI 29 ± 2 kg / m2) with increased CVRF profile were included in this prospective study...
2017: PloS One
https://www.readbyqxmd.com/read/28402068/eating-related-psychopathology-and-food-addiction-in-adolescent-psychiatric-inpatients
#10
Özgür Albayrak, Manuel Föcker, Josephine Kliewer, Simon Esber, Triinu Peters, Martina de Zwaan, Johannes Hebebrand
OBJECTIVE: Our aims were to investigate the relationship between food addiction and mental disorders including eating disorders (ED), eating-related psychopathology and body mass index-standard deviation score in a sample of adolescent psychiatric inpatients. METHODS: Food addiction was assessed with the Yale Food Addiction Scale (YFAS). Eating-related psychopathology was measured with the Three-Factor Eating Questionnaire (TFEQ). Psychiatric diagnoses were assessed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition...
May 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28396491/differences-in-swimming-ability-and-its-response-to-starvation-among-male-and-female-gambusia-affinis
#11
Jiangtao Li, Xiaotao Lin, Zhongneng Xu, Jun Sun
To explore the differences in the swimming ability and environmental adaptive abilities between male and female Gambusia affinis, we assessed the differences in burst swimming speeds (Uburst), critical swimming speeds (Ucrit) and their related fin areas, and consumption of energy substances after starvation at 0 (control group), 15, 30, 45, and 60 days, respectively. The results showed that the pectoral and caudal fin areas did not differ significantly between male and female G. affinis However, the dry mass, condition factors, and absolute contents of glycogen, lipids, and proteins were significantly elevated in females in the control group (P<0...
April 10, 2017: Biology Open
https://www.readbyqxmd.com/read/28396048/effects-of-aroma-and-taste-independently-or-in-combination-on-appetite-sensation-and-subsequent-food-intake
#12
Wenting Yin, Louise Hewson, Robert Linforth, Moira Taylor, Ian D Fisk
Food flavour is important in appetite control. The effects of aroma and taste, independently or in combination, on appetite sensation and subsequent food intake, were studied. Twenty-six females (24 ± 4 years, 20.9 ± 1.9 kg⋅m(-2)) consumed, over 15 min period, one of four sample drinks as a preload, followed by an ad libitum consumption of a pasta meal (after 65 min). Sample drinks were: water (S1, 0 kcal), water with strawberry aroma (S2, 0 kcal), water with sucrose and citric acid (S3, 48 kcal) and water with strawberry aroma, sucrose and citric acid (S4, 48 kcal)...
April 7, 2017: Appetite
https://www.readbyqxmd.com/read/28377876/cannabinoid-type-1-receptor-containing-axons-innervate-npy-agrp-neurons-in-the-mouse-arcuate-nucleus
#13
Yury M Morozov, Marco Koch, Pasko Rakic, Tamas L Horvath
OBJECTIVES: Phytocannabinoids, such as THC and endocannabinoids, are well known to promote feeding behavior and to control energy metabolism through cannabinoid type 1 receptors (CB1R). However, the underlying mechanisms are not fully understood. Generally, cannabinoid-conducted retrograde dis-inhibition of hunger-promoting neurons has been suggested to promote food intake, but so far it has not been demonstrated due to technical limitations. METHODS: We applied immunohistochemical labeling of CB1R for light microscopy and electron microscopy combined with three-dimensional reconstruction from serial sections in CB1R-expressing and CB1R-null mice, which served as a negative control...
April 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/28372566/the-cross-cutting-contribution-of-the-end-of-neglected-tropical-diseases-to-the-sustainable-development-goals
#14
REVIEW
Mathieu Bangert, David H Molyneux, Steve W Lindsay, Christopher Fitzpatrick, Dirk Engels
The Sustainable Development Goals (SDGs) call for an integrated response, the kind that has defined Neglected Tropical Diseases (NTDs) efforts in the past decade.NTD interventions have the greatest relevance for SDG3, the health goal, where the focus on equity, and its commitment to reaching people in need of health services, wherever they may live and whatever their circumstances, is fundamentally aligned with the target of Universal Health Coverage. NTD interventions, however, also affect and are affected by many of the other development areas covered under the 2030 Agenda...
April 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28371861/growth-curve-and-diet-density-affect-eating-motivation-behavior-and-body-composition-of-broiler-breeders-during-rearing
#15
J de Los Mozos, A I García-Ruiz, L A den Hartog, M J Villamide
The aim of this work has been to assess the effect of diet density [control (CON) or 15% diluted (DIL)] and growth curve [recommended by the genetic line (RBW) or 15% heavier (HBW)] and their interaction on BW uniformity, feeding motivation, behavior, and body composition of broiler breeder pullets. A total of 3,000 one-day-old female breeders Ross 308, distributed in 20 pens, was randomly assigned to each treatment. Feed allowance was weekly adjusted to reach the desired BW. Feed was provided as pelleted (zero to 3 wk) and crumble (4 to 19 wk)...
March 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28360832/a-life-without-hunger-the-ups-and-downs-to-modulating-melanocortin-3-receptor-signaling
#16
REVIEW
Andrew A Butler, Clemence Girardet, Maria Mavrikaki, James L Trevaskis, Heather Macarthur, Daniel L Marks, Susan A Farr
Melanocortin neurons conserve body mass in hyper- or hypo-caloric conditions by conveying signals from nutrient sensors into areas of the brain governing appetite and metabolism. In mice, melanocortin-3 receptor (MC3R) deletion alters nutrient partitioning independently of hyperphagia, promoting accumulation of fat over muscle mass. Enhanced rhythms in insulin and insulin-responsive metabolic genes during hypocaloric feeding suggest partial insulin resistance and enhanced lipogenesis. However, exactly where and how MC3Rs affect metabolic control to alter nutrient partitioning is not known...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28359370/ramadan-model-of-intermittent-fasting-for-28%C3%A2-d-had-no-major-effect-on-body-composition-glucose-metabolism-or-cognitive-functions-in-healthy-lean-men
#17
Nina M Harder-Lauridsen, Astrid Rosenberg, Fabiana B Benatti, Julie A Damm, Carsten Thomsen, Erik L Mortensen, Bente K Pedersen, Rikke Krogh-Madsen
OBJECTIVES: There has been a parallel increase in the incidence of obesity and diabetes as well as the number of daily meals. However, evidence is lacking regarding the role of intermittent fasting. The aim of this study was to determine the effects of a Ramadan model of intermittent fasting (RIF; 14 h of daytime abstinence from food and drinking) for 28 d on body composition, glucose metabolism, and cognitive function. METHODS: Ten healthy, lean men were included in a nonrandomized, crossover, intervention study...
May 2017: Nutrition
https://www.readbyqxmd.com/read/28344903/comparison-of-consumption-behavior-and-appetite-sensations-among-patients-with-type-2-diabetes-mellitus-after-bariatric-surgery
#18
Chun Yeh, Hsien-Hao Huang, Shu-Chun Chen, Tung-Fang Chen, Kong-Han Ser, Chih-Yen Chen
BACKGROUND: The promising postsurgical weight loss and remission of type 2 diabetes (T2D) from bariatric surgery can be attributed to modified eating physiology after surgical procedures. We sought to investigate the changes in the parameters of consumption behaviors and appetite sensations induced by a mixed meal tolerance test, and to correlate these alterations with age, body mass index, C-peptide levels, and duration of T2D 1 year after bariatric surgery. METHODS: A total of 16 obese patients with T2D who underwent mini-gastric bypass (GB) and 16 patients who underwent sleeve gastrectomy (SG) were enrolled in this study and evaluated using a mixed meal tolerance test one year after surgery...
2017: PeerJ
https://www.readbyqxmd.com/read/28342765/hippocampal-insulin-resistance-and-altered-food-decision-making-as-players-on-obesity-risk
#19
REVIEW
Amanda Brondani Mucellini, Natasha Kim de Oliveira da Fonseca, Gisele Gus Manfro, Patrícia Pelufo Silveira
There are increasing evidences that hippocampus can modulate the decision of what, when and how much to eat, in addition to its already recognized role in learning and memory processes. Insulin also has been linked to brain functions such as feeding behavior and the imbalance of its mechanism of action on hippocampus is being related to cognitive dysfunction. The discussion here is whether changes in insulin action could contribute to intake dysregulation and obesogenic behavior as a primary consequence of impairing hippocampal functioning, aside from the role of this hormone on obesity development through peripheral metabolic pathways...
March 22, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28335489/effects-of-the-mediterranean-diet-before-and-after-weight-loss-on-eating-behavioral-traits-in-men-with-metabolic-syndrome
#20
Élise Carbonneau, Marie-Michelle Royer, Caroline Richard, Patrick Couture, Sophie Desroches, Simone Lemieux, Benoît Lamarche
The objective of this study was to investigate the impact of the Mediterranean diet (MedDiet) consumed before and after weight loss on eating behavioral traits as measured by the Three-Factor Eating Questionnaire (TFEQ) in men with metabolic syndrome (MetS). In this fixed sequence study, 19 men with MetS (National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) criteria), aged between 24 and 62 years, first consumed a five-week standardized North American control diet followed by a five-week MedDiet, both under weight-maintaining controlled-feeding conditions...
March 19, 2017: Nutrients
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