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https://www.readbyqxmd.com/read/29897544/consuming-lower-protein-nutrition-bars-with-added-leucine-elicits-postprandial-changes-in-appetite-sensations-in-healthy-women
#1
Douglas R Bolster, Maike Rahn, Alison G Kamil, Lindsey T Bristol, Shellen R Goltz, Heather J Leidy, Melvin Blaze Mt, Michael A Nunez, Elizabeth Guo, Jianquan Wang, Laura S Harkness
Background: Higher-protein meals (>25 g protein/meal) have been associated with enhanced satiety but the role of amino acids is unclear. Leucine has been proposed to stimulate satiety in rodents but has not been assessed in humans. Objective: We assessed the acute effects of lower-protein nutrition bars, enhanced with a leucine peptide (LP), on postprandial appetite sensations in combination with plasma leucine and peptide YY (PYY) in healthy women. Methods: Utilizing a double-blind randomized crossover design, 40 healthy women [28 ± 7...
April 20, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29893447/intense-physical-exercise-potentiates-glucose-inhibitory-effect-over-food-intake-of-male-wistar-rats
#2
Joao Paulo Cavalcanti-de-Albuquerque, Grasielle Clotildes Kincheski, Ruy Andrade Louzada, Antônio Galina, Anna Paola Trindade Rocha Pierucci, Denise P Carvalho
NEW FINDINGS: What is the central question of this study? Physical exercise has emerged as a non-pharmacological treatment for obesity by promoting changes in energy balance. Despite the accumulated knowledge about exercise effects on energy expenditure, the central question of this study is to understand how an acute session of exercise might affect food intake of male Wistar rats. What is the main finding? The main finding of this work is that food intake in male Wistar rats is decreased in the first hour after physical exercise independent of the intensity...
June 12, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29890186/is-brain-response-to-food-rewards-related-to-overeating-a-test-of-the-reward-surfeit-model-of-overeating-in-children
#3
Shana Adise, Charles F Geier, Nicole J Roberts, Corey N White, Kathleen L Keller
The reward surfeit model of overeating suggests that heightened brain response to rewards contributes to overeating and subsequent weight gain. However, previous studies have not tested whether brain response to reward is associated with food intake, particularly during childhood, a period of dynamic development in reward and inhibitory control neurocircuitry. We conducted functional magnetic resonance imaging (fMRI) with 7-11-year-old children (n = 59; healthy weight, n = 31; overweight, n = 28; 54% female) while they played a modified card-guessing paradigm to examine blood-oxygen-level-dependent (BOLD) response to anticipating and winning rewards (food, money, neutral)...
June 8, 2018: Appetite
https://www.readbyqxmd.com/read/29876881/cocaine-blocks-effects-of-hunger-hormone-ghrelin-via-interaction-with-neuronal-sigma-1-receptors
#4
David Aguinaga, Mireia Medrano, Arnau Cordomí, Mireia Jiménez-Rosés, Edgar Angelats, Mireia Casanovas, Ignacio Vega-Quiroga, Enric I Canela, Milos Petrovic, Katia Gysling, Leonardo Pardo, Rafael Franco, Gemma Navarro
Despite ancient knowledge on cocaine appetite-suppressant action, the molecular basis of such fact remains unknown. Addiction/eating disorders (e.g., binge eating, anorexia, bulimia) share a central control involving reward circuits. However, we here show that the sigma-1 receptor (σ1 R) mediates cocaine anorectic effects by interacting in neurons with growth/hormone/secretagogue (ghrelin) receptors. Cocaine increases colocalization of σ1 R and GHS-R1a at the cell surface. Moreover, in transfected HEK-293T and neuroblastoma SH-SY5Y cells, and in primary neuronal cultures, pretreatment with cocaine or a σ1 R agonist inhibited ghrelin-mediated signaling, in a similar manner as the GHS-R1a antagonist YIL-781...
June 7, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29869415/hunger-and-satiety-signaling-modeling-two-hypothalamomedullary-pathways-for-energy-homeostasis
#5
REVIEW
Kazuhiro Nakamura, Yoshiko Nakamura
The recent discovery of the medullary circuit driving "hunger responses" - reduced thermogenesis and promoted feeding - has greatly expanded our knowledge on the central neural networks for energy homeostasis. However, how hypothalamic hunger and satiety signals generated under fasted and fed conditions, respectively, control the medullary autonomic and somatic motor mechanisms remains unknown. Here, in reviewing this field, we propose two hypothalamomedullary neural pathways for hunger and satiety signaling...
June 4, 2018: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/29862395/hibiscus-and-lemon-verbena-polyphenols-modulate-appetite-related-biomarkers-in-overweight-subjects-a-randomized-controlled-trial
#6
Marina Boix-Castejón, María Herranz-López, Alberto Pérez Gago, Mariló Olivares-Vicente, Nuria Caturla, Enrique Roche, Vicente Micol
TRIAL DESIGN: Plant-derived polyphenols have shown potential to alleviate obesity-related pathologies by a multi-targeted mechanism in animal models and human intervention studies. A dietary supplement based on a combination of Lippia citriodora (LC) and Hibiscus sabdariffa (HS) polyphenolic extracts was assayed in a double blind and placebo-controlled intervention study with 54 overweight subjects. METHODS: Blood pressure, body weight, height, triceps, biceps and abdominal skinfold thickness, and arm and abdominal circumferences were taken at the baseline, 30 and 60 days of the intervention period...
June 4, 2018: Food & Function
https://www.readbyqxmd.com/read/29843787/sex-differences-in-basal-hypothalamic-anorectic-and-orexigenic-gene-expression-and-the-effect-of-quantitative-and-qualitative-food-restriction
#7
S D Caughey, P W Wilson, N Mukhtar, S Brocklehurst, A Reid, R B D'Eath, T Boswell, I C Dunn
BACKGROUND: Research into energy balance and growth has infrequently considered genetic sex, yet there is sexual dimorphism for growth across the animal kingdom. We test the hypothesis that in the chicken, there is a sex difference in arcuate nucleus neuropeptide gene expression, since previous research indicates hypothalamic AGRP expression is correlated with growth potential and that males grow faster than females. Because growth has been heavily selected in some chicken lines, food restriction is necessary to improve reproductive performance and welfare, but this increases hunger...
May 29, 2018: Biology of Sex Differences
https://www.readbyqxmd.com/read/29787831/oleoylethanolamide-increases-the-expression-of-ppar-%C3%AE-and-reduces-appetite-and-body-weight-in-obese-people-a-clinical-trial
#8
Payahoo Laleh, Khaje-Bishak Yaser, Barzegari Abolfazl, Alipour Shahriar, Asghari Jafarabadi Mohammad, Farrin Nazila, Ostadrahimi Alireza
Obesity is a crucial public health problem worldwide and is considered as the main cause of many chronic diseases. The present study evaluated the effects of Oleoylethanolamide (OEA) supplementation on proximal proliferator-activated receptor-α (PPAR-α) gene expression, appetite sensations, and anthropometric measurements in obese people. This randomized, double-blind, placebo-controlled clinical trial was carried out on 60 healthy obese people in Tabriz, Iran, in 2016. The eligible subjects were divided into an intervention group (who received two 125 mg OEA capsules daily) and a placebo group (who received the same amount of starches) and treated for 60 days...
May 19, 2018: Appetite
https://www.readbyqxmd.com/read/29751193/adolescents-perceive-a-low-added-sugar-adequate-fiber-diet-to-be-more-satiating-and-equally-palatable-compared-to-a-high-added-sugar-low-fiber-diet-in-a-randomized-crossover-design-controlled-feeding-pilot-trial
#9
Tanya M Halliday, Sarah V Liu, Lori B Moore, Valisa E Hedrick, Brenda M Davy
BACKGROUND: High added sugar (AS) intake is associated with obesity and poor diet quality. Guidelines recommended limiting AS to 5-10% of total energy intake, but palatability and feasibility of this AS intake level is uncertain. OBJECTIVE: To compare adolescents' perceptions of hunger, fullness, and palatability in response to a low AS adequate fiber (LASAF; 5% total energy from AS and 13.5 g fiber/1000 kcal) and a high AS low fiber (HASLF; 25% total energy form AS and 8...
May 5, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29748653/potential-effects-of-fat-mass-and-fat-free-mass-on-energy-intake-in-different-states-of-energy-balance
#10
REVIEW
R James Stubbs, M Hopkins, G S Finlayson, C Duarte, C Gibbons, J E Blundell
Recently models have attempted to integrate the functional relationships of fat mass (FM) and fat-free mass (FFM) with the control of human energy intake (EI). Cross-sectional evidence suggests that at or close to EB, FFM is positively related to hunger and EI, whereas FM either shows a weak negative or no association with ad libitum EI. Further analysis suggests that the effects of FFM and FM on EI may be mediated by resting metabolic rate (RMR). These studies suggest that energy turnover is associated with EI and the largest determinant of energy requirements in most humans is FFM...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29715502/a-multimodal-investigation-of-impulsivity-as-a-moderator-of-the-relation-between-momentary-elevations-in-negative-internal-states-and-subsequent-dietary-lapses
#11
Stephanie M Manasse, Rebecca J Crochiere, Diane H Dallal, Edward W Lieber, Leah M Schumacher, Ross D Crosby, Meghan L Butryn, Evan M Forman
Suboptimal outcomes from behavioral weight loss (BWL) treatments are partially attributable to accumulated instances of non-adherence to dietary prescriptions (i.e., dietary lapses). Results identifying negative internal triggers for dietary lapses are inconsistent, potentially due to individual differences that impact how individuals respond to cues. Impulsivity is one factor that likely influences reactivity to internal states. We examined three dimensions of impulsivity (delay discounting, inhibitory control, and negative urgency) as moderators of the relation between affective and physical states and subsequent dietary lapses at the beginning of BWL...
April 30, 2018: Appetite
https://www.readbyqxmd.com/read/29705495/weight-labeling-and-disordered-eating-among-adolescent-girls-longitudinal-evidence-from-the-national-heart-lung-and-blood-institute-growth-and-health-study
#12
Jeffrey M Hunger, A Janet Tomiyama
PURPOSE: Weight stigma is implicated in disordered eating, but much of this research focuses on forms of stigma such as weight-based teasing. METHODS: In a large cohort of adolescent girls (N = 2,036), we tested the hypothesis that being labeled as "too fat" by others predicts subsequent greater disordered eating cognitions and behaviors. RESULTS: Compared with girls who did not report weight labeling, girls who were labeled at age 14 showed an increase in unhealthy weight control behaviors and disordered eating cognitions over the subsequent 5 years...
April 25, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29691526/black-pepper-based-beverage-induced-appetite-suppressing-effects-without-altering-postprandial-glycaemia-gut-and-thyroid-hormones-or-gastrointestinal-well-being-a-randomized-crossover-study-in-healthy-subjects
#13
Yoghatama Cindya Zanzer, Merichel Plaza, Anestis Dougkas, Charlotta Turner, Elin Östman
Pleiotropic effects of spices on health, particularly on glucose metabolism and energy regulation, deserve further clinical investigation into their efficacy. The aim of the current study was to evaluate whether consumption of a black pepper-based beverage (BPB) preload containing 20 mg gallic acid equivalent (GAE) would exert any effect on postprandial glycaemia, appetite sensations, gut hormones, thyroid function, and gastrointestinal well-being after a white wheat bread (WWB) challenge meal containing 50 g available carbohydrates (CHO) compared to a control beverage...
April 25, 2018: Food & Function
https://www.readbyqxmd.com/read/29686412/short-term-effects-of-six-greek-honey-varieties-on-glycemic-response-a-randomized-clinical-trial-in-healthy-subjects
#14
Theodora Gourdomichali, Emilia Papakonstantinou
BACKGROUND/OBJECTIVES: This randomized, double blind, cross-over study investigated the glycemic response to six Greek honey grades differing in floral source and carbohydrate composition. SUBJECTS/METHODS: Eleven clinically and metabolically healthy, fasting individuals (27 ± 7 years; nine women; BMI 24 ± 4 kg/m2 ) received isoglucidic test meals (50 g available carbohydrate) and 50 g glucose reference, in random order. GI was calculated using the FAO/WHO method...
April 24, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29684984/effects-of-preoperative-oral-carbohydrate-administration-on-patient-well-being-and-satisfaction-in-thyroid-surgery
#15
A Ram Doo, Hyunsup Hwang, Min-Jong Ki, Jun-Rae Lee, Dong-Chan Kim
Background: Although the positive effects of preoperative oral carbohydrate administration on clinical outcomes following major surgery have been reported continuously, there are few investigations of them in minor surgical patients. The present study was designed to examine the effects of preoperative oral carbohydrate administration on patient well-being and satisfaction in patients undergoing thyroidectomy. Methods: Fifty adults aged 20-65 years and scheduled for elective thyroidectomy in first schedule in the morning were allocated to one of two groups...
April 24, 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29680359/effects-of-6-vs-3-eucaloric-meal-patterns-on-glycaemic-control-and-satiety-in-people-with-impaired-glucose-tolerance-or-overt-type-2-diabetes-a-randomized-trial
#16
E Papakonstantinou, M D Kontogianni, P Mitrou, E Magriplis, D Vassiliadi, T Nomikos, V Lambadiari, E Georgousopoulou, G Dimitriadis
BACKGROUND/OBJECTIVES: The study aimed to compare the effects of two eucaloric meal patterns (3 vs 6 meals/day) on glycaemic control and satiety in subjects with impaired glucose tolerance and plasma glucose (PG) levels 140-199mg/dL at 120min (IGT-A) or PG levels 140-199mg/dL at 120min and >200mg/dL at 30/60/90min post-oral glucose load on 75-g OGTT (IGT-B), or overt treatment-naïve type 2 diabetes (T2D). SUBJECTS/METHODS: In this randomized crossover study, subjects with IGT-A (n=15, BMI: 32...
April 6, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29659892/effect-of-physiological-state-on-female-melon-fly-diptera-tephritidae-attraction-to-host-and-food-odor-in-the-field
#17
Roger I Vargas, Jaime C Piñero, Neil W Miller
Foraging behavior of wild female melon fly, Bactrocera (Zeugodacus) cucurbitae Coquillett, a worldwide pest of economically important cucurbit crops, was examined through mark and recapture studies in both wild (Kona: dominated by the invasive weed ivy gourd, Coccinea grandis [L.] Voigt [Cucurbitaceae]), and cultivated (Kapoho: dominated by papaya, Carica papaya L. [Caricaceae] orchards) habitats on Hawaii Island. In particular, the extent to which wild melon flies and color-marked F2 females responded to cucumber odor and Solulys yeast hydrolysate laced with ammonium acetate (1%, wt/vol) according to sexual maturity stage and degree of protein hunger was documented...
May 28, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29629030/household-food-insecurity-diet-quality-and-weight-status-among-indigenous-women-mah-meri-in-peninsular-malaysia
#18
Chong Su Pei, Geeta Appannah, Norhasmah Sulaiman
BACKGROUND/OBJECTIVES: This cross-sectional study assessed household food security status and determined its association with diet quality and weight status among indigenous women from the Mah Meri tribe in Peninsular Malaysia. SUBJECTS/METHODS: The Radimer/Cornell Hunger and Food Insecurity Instrument and the Malaysian Healthy Eating Index (HEI) were used to assess household food security status and diet quality, respectively. Information on socio-demographic characteristics and 24-hour dietary recall data were collected through face-to-face interview, and anthropometric measurements including weight, height, and body mass index (BMI) were obtained from 222 women...
April 2018: Nutrition Research and Practice
https://www.readbyqxmd.com/read/29617527/association-of-hidradenitis-suppurativa-with-t-helper-1-t-helper-17-phenotypes-a-semantic-map-analysis
#19
Rahel Thomi, Simone Cazzaniga, S Morteza Seyed Jafari, Christoph Schlapbach, Robert E Hunger
Importance: In spite of progress in understanding the mechanisms underlying hidradenitis suppurativa (HS) as an inflammatory skin disease, there is still a demand for an overview on immunopathogenesis of HS. Objective: To demonstrate the importance of the type 1/type 17 immune response in lesional HS skin by drawing a semantic connectivity map. Design, Setting, and Participants: Single-center case series of 24 patients with HS. Association of HS with T helper 1/T helper 17 (TH1/TH17) phenotype was assessed using semantic map analysis...
May 1, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29605841/secukinumab-versus-adalimumab-for-psoriatic-arthritis-comparative-effectiveness-up-to-48-weeks-using-a-matching-adjusted-indirect-comparison
#20
Peter Nash, Iain B McInnes, Philip J Mease, Howard Thom, Matthias Hunger, Andreas Karabis, Kunal Gandhi, Shephard Mpofu, Steffen M Jugl
INTRODUCTION: Secukinumab and adalimumab are approved for adults with active psoriatic arthritis (PsA). In the absence of direct randomized controlled trial (RCT) data, matching-adjusted indirect comparison can estimate the comparative effectiveness in anti-tumor necrosis factor (TNF)-naïve populations. METHODS: Individual patient data from the FUTURE 2 RCT (secukinumab vs. placebo; N = 299) were adjusted to match baseline characteristics of the ADEPT RCT (adalimumab vs...
June 2018: Rheumatology and Therapy
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