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Corneal Biomechanics

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https://www.readbyqxmd.com/read/28514942/corneal-biomechanical-properties-in-healthy-children-measured-by-corneal-visualization-scheimpflug-technology
#1
Miao He, Hui Ding, Hong He, Chi Zhang, Liangping Liu, Xingwu Zhong
BACKGROUND: The aim of this study was to evaluate corneal biomechanical properties in a population of healthy children in China using corneal visualization Scheimpflug technology (CST). METHODS: All children underwent complete bi-ocular examinations. CST provided intraocular pressure (IOP) and corneal biomechanical parameters, including time, velocity, length and deformation amplitude at first applanation (A1T, A1V, A1L, A1DA), at second applanation (A2T, A2V, A2L, A2DA), highest concavity time (HCT), maximum deformation amplitude (MDA), peak distance (PD), and radius of curvature (RoC)...
May 17, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28501948/corneal-tomography-and-biomechanics-in-primary-pterygium
#2
M Vanathi, Sahil Goel, Anita Ganger, Tushar Agarwal, T Dada, Sudarshan Khokhar
PURPOSE: To study the Scheimpflug's imaging and corneal biomechanics in primary pterygium. METHODS: A prospective observational study of 55 patients with unilateral primary nasal pterygium was done. The normal fellow eyes of patients with pterygium were taken as controls. Clinical parameters noted included visual acuity, values of corneal curvature by doing Scheimpflug imaging, wavefront aberrations in terms of higher and lower-order aberrations and corneal hysteresis (CH) as well as corneal resistance factor (CRF) values by using ocular response analyzer...
May 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28496302/goldmann-tonometer-error-correcting-prism-clinical-evaluation
#3
Sean McCafferty, Garrett Lim, William Duncan, Eniko T Enikov, Jim Schwiegerling, Jason Levine, Corin Kew
PURPOSE: Clinically evaluate a modified applanating surface Goldmann tonometer prism designed to substantially negate errors due to patient variability in biomechanics. METHODS: A modified Goldmann prism with a correcting applanation tonometry surface (CATS) was mathematically optimized to minimize the intraocular pressure (IOP) measurement error due to patient variability in corneal thickness, stiffness, curvature, and tear film adhesion force. A comparative clinical study of 109 eyes measured IOP with CATS and Goldmann prisms...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28494490/biomechanical-responses-of-lamina-cribrosa-to-intraocular-pressure-change-assessed-by-optical-coherence-tomography-in-glaucoma-eyes
#4
Harry Quigley, Karun Arora, Sana Idrees, Francisco Solano, Sahar Bedrood, Christopher Lee, Joan Jefferys, Thao Nguyen
Purpose: The purpose of this study was to measure change in anterior lamina cribrosa depth (ALD) globally and regionally in glaucoma eyes at different intraocular pressures (IOP). Methods: Twenty-seven glaucoma patients were imaged before and after IOP-lowering procedures using optical coherence tomography. The anterior lamina was marked in approximately 25 locations in each of six radial scans to obtain global and regional estimates of ALD. ALD and its change with IOP were compared with optic disc damage, nerve fiber layer thickness, and visual field loss...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28489806/the-relationship-between-corneal-biomechanics-and-anterior-segment-parameters-in-the-early-stage-of-orthokeratology-a-pilot-study
#5
Renai Chen, Xinjie Mao, Jun Jiang, Meixiao Shen, Yan Lian, Bin Zhang, Fan Lu
To investigate the relationship between corneal biomechanics and anterior segment parameters in the early stage of overnight orthokeratology.Twenty-three eyes from 23 subjects were involved in the study. Corneal biomechanics, including corneal hysteresis (CH) and corneal resistance factor (CRF), and parameters of the anterior segment, including corneal curvature, central corneal thickness (CCT), and corneal sublayers' thickness, were measured at baseline and day 1 and 7 after wearing orthokeratology lens. One-way analysis of variance with repeated measures was used to compare the longitudinal changes and partial least squares linear regression was used to explore the relationship between corneal biomechanics and anterior segment parameters...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28486312/biomechanical-and-histopathologic-effects-of-pulsed-light-accelerated-epithelium-on-off-corneal-collagen-cross-linking
#6
Xiaoyu Zhang, Ling Sun, Yang Shen, Mi Tian, Jing Zhao, Yu Zhao, Meiyan Li, Xingtao Zhou
PURPOSE: This study aimed to compare the biomechanical and histopathologic effects of transepithelial and accelerated epithelium-off pulsed-light accelerated corneal collagen cross-linking (CXL). METHODS: A total of 24 New Zealand rabbits were analyzed after sham operation (control) or transepithelial or epithelium-off operation (45 mW/cm for both). The transepithelial group was treated with pulsed-light ultraviolet A for 5 minutes 20 seconds, and the epithelium-off group was treated for 90 seconds...
May 8, 2017: Cornea
https://www.readbyqxmd.com/read/28472178/influence-of-eye-biometrics-and-corneal-micro-structure-on-noncontact-tonometry
#7
Danilo A Jesus, Małgorzata Majewska, Patrycja Krzyżanowska-Berkowska, D Robert Iskander
PURPOSE: Tonometry is widely used as the main screening tool supporting glaucoma diagnosis. Still, its accuracy could be improved if full knowledge about the variation of the corneal biomechanical properties was available. In this study, Optical Coherence Tomography (OCT) speckle statistics are used to infer the organisation of the corneal micro-structure and hence, to analyse its influence on intraocular pressure (IOP) measurements. METHODS: Fifty-six subjects were recruited for this prospective study...
2017: PloS One
https://www.readbyqxmd.com/read/28470657/-morphologic-corneal-changes-after-crosslinking-for-keratoconus
#8
P L Müller, K U Löffler, M Kohlhaas, F G Holz, M C Herwig-Carl
Keratoconus is a relatively common (1 : 2000) bilateral disease leading to a change in biochemical and biomechanical corneal structure as well as thinning and ectasia. For more than 10 years, crosslinking has been a therapeutic option in cases of progression. Using riboflavin and UVA-radiation, the anterior corneal stroma (300 µm) gets stiffened by crosslinking of collagen fibers. When protocols and limitations are adhered, the procedure is described to be effective and of low-risk. This review gives an overview about physiologic and pathologic changes in keratoconic corneas before and after crosslinking...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28461014/comparison-of-corneal-biomechanical-properties-between-indian-and-chinese-adults
#9
Jacqueline Chua, Monisha E Nongpiur, Wanting Zhao, Yih Chung Tham, Preeti Gupta, Charumathi Sabanayagam, Tin Aung, Tien Yin Wong, Ching-Yu Cheng
PURPOSE: To investigate the difference in corneal hysteresis (CH) and corneal resistance factor (CRF) between Indian and Chinese populations. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Three hundred eighty-two Singaporean Indian persons and 764 Singaporean Chinese 50 years of age or older were included from the Singapore Indian Eye Study and Singapore Chinese Eye Study, respectively. METHODS: Participants underwent standardized systemic and ocular examinations and interviewer-administered questionnaires for risk factor assessment...
April 28, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28450146/alternatives-to-eye-bank-native-tissue-for-corneal-stromal-replacement
#10
REVIEW
Isabelle Brunette, Cynthia J Roberts, François Vidal, Mona Harissi-Dagher, Jean Lachaine, Heather Sheardown, Georges M Durr, Stéphanie Proulx, May Griffith
Corneal blindness is a major cause of blindness in the world and corneal transplantation is the only widely accepted treatment to restore sight in these eyes. However, it is becoming increasingly difficult for eye banks to meet the increasing demand for transplantable tissue, which is in part due to population aging. Donor tissue shortage is therefore a growing concern globally and there is a need for alternatives to human donor corneas. Biosynthetic corneal substitutes offer several significant advantages over native corneas: Large-scale production offers a powerful potential solution to the severe shortage of human donor corneas worldwide; Good manufacturing practices ensure sterility and quality control; Acellular corneal substitutes circumvent immune rejection induced by allogeneic cells; Optical and biomechanical properties of the implants can be adapted to the clinical need; and finally these corneal substitutes could benefit from new advances in biomaterials science, such as surface coating, functionalization and nanoparticles...
April 24, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28444523/iop-measurement-in-silicone-oil-tamponade-eyes-by-corvis-st-tonometer-goldmann-applanation-tonometry-and-non-contact-tonometry
#11
Yang Zhang, Lin Zheng, Ailing Bian, Qi Zhou
PURPOSE: To compare the postoperative intraocular pressure (IOP) of eyes following pars plana vitrectomy (PPV) combined with intravitreal silicone oil (SO) tamponade by Corneal Visualization Scheimpflug Technology (CST), Goldmann applanation tonometry (GAT) and non-contact tonometry (NCT). METHODS: Thirty-eight participants who had undergone PPV combined with SO tamponade to treat vitreoretinal diseases were enrolled. Postoperative IOP measurements were obtained using CST, NCT and GAT...
April 25, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28430332/relationship-between-corneal-biomechanical-properties-and-optic-nerve-head-changes-after-deep-sclerectomy
#12
Laura Díez-Álvarez, Francisco J Muñoz-Negrete, Pilar Casas-Llera, Noelia Oblanca, Victoria de Juan, Gema Rebolleda
PURPOSE: To evaluate corneal biomechanical properties and optic nerve head (ONH) changes following deep sclerectomy (DS) and the relation to each other. METHODS: Forty-nine eyes with primary open-angle glaucoma that underwent DS were studied. Corneal biomechanical properties were assessed using the Ocular Response Analyzer and the ONH was evaluated by Spectralis optical coherence tomography with enhanced depth imaging technology before surgery and 3 months postoperatively...
April 4, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28424868/non-invasive-measurements-of-the-dynamic-changes-in-the-ciliary-muscle-crystalline-lens-morphology-and-anterior-chamber-during-accommodation-with-a-high-resolution-oct
#13
José J Esteve-Taboada, Alberto Domínguez-Vicent, Daniel Monsálvez-Romín, Antonio J Del Águila-Carrasco, Robert Montés-Micó
PURPOSE: The purpose of the study was to assess non-invasively the changes in the anterior chamber eye, crystalline lens morphology, and ciliary muscle during accommodation by means of an anterior chamber optical coherence tomographer (OCT), and correlate them with vergence. METHODS: Twenty-five eyes of twenty-five healthy subjects, whose mean age was 29.9±7.1 years, were included and measured with an anterior chamber OCT. The central corneal thickness (CCT), anterior chamber depth (ACD), anterior crystalline lens radius of curvature (ALRC), crystalline lens thickness (CLT), and ciliary muscle area (CMA) were measured for each participant at 0, -1, -2, and -3 D of target vergence...
April 20, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28407167/introduction-of-two-novel-stiffness-parameters-and-interpretation-of-air-puff-induced-biomechanical-deformation-parameters-with-a-dynamic-scheimpflug-analyzer
#14
Cynthia J Roberts, Ashraf M Mahmoud, Jeffrey P Bons, Arif Hossain, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra, Renato Ambrósio
PURPOSE: To investigate two new stiffness parameters and their relationships with the dynamic corneal response (DCR) parameters and compare normal and keratoconic eyes. METHODS: Stiffness parameters are defined as Resultant Pressure at inward applanation (A1) divided by corneal displacement. Stiffness parameter A1 uses displacement between the undeformed cornea and A1 and stiffness parameter highest concavity (HC) uses displacement from A1 to maximum deflection during HC...
April 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28379651/visual-quality-after-femtosecond-laser-small-incision-lenticule-extraction
#15
Huamao Miao, Tian Han, Mi Tian, Xiaoying Wang, Xingtao Zhou
Femtosecond laser small incision lenticule extraction (SMILE) is a newly developed form of "flapless" corneal refractive surgery with all-in-one technology. Femtosecond laser SMILE is increasingly attractive for both doctors and patients because it is minimally invasive and does not require a flap to be lifted during surgery. It exhibits many advantages in terms of morphology, biomechanical effects, corneal wound healing, and nerve rehabilitation. However, visual quality assessment after refractive surgeries is just as important as these advantages and correlates with patient satisfaction...
March 29, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28379648/cap-lenticular-adhesion-during-small-incision-lenticular-extraction-surgery-causative-factors-and-outcomes
#16
Rohit Shetty, Nikhil Negalur, Rushad Shroff, Kalyani Deshpande, Chaitra Jayadev
PURPOSE: To study the factors causing cap lenticular adhesion (CLA), a rare complication of small incision lenticule extraction (SMILE) surgery, and its effect on surgical outcomes. DESIGN: A prospective, observational, cross-sectional study involving 550 eyes of 285 subjects. METHODS: SMILE was performed using the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) with a minimum of 3 months follow-up. Preoperative visual quality assessment, measurement of corneal biomechanics, and Bowman membrane imaging were performed...
March 29, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28351927/factors-influencing-intraocular-pressure-corneal-thickness-and-corneal-biomechanics-after-congenital-cataract-surgery
#17
Amir Faramarzi, Sepehr Feizi, Ali Maghsoodlou
AIMS: This study aims to compare intraocular pressure (IOP), central corneal thickness (CCT) and corneal biomechanics among patients with aphakia, patients with primary and secondary pseudophakia and matched controls following congenital cataract surgery and to investigate the factors influencing these variables. METHODS: This study included 36 aphakic eyes, 47 primary pseudophakic eyes and 30 secondary pseudophakic eyes. Thirty-four normal eyes of matched volunteers were recruited for comparisons...
March 28, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28341831/the-relationship-between-retinal-nerve-fibre-layer-thickness-profiles-and-corvisst-tonometry-measured-biomechanical-properties-in-young-healthy-subjects
#18
Masato Matsuura, Hiroshi Murata, Shunsuke Nakakura, Yoshitaka Nakao, Takehiro Yamashita, Kazunori Hirasawa, Yuri Fujino, Yoshiaki Kiuchi, Ryo Asaoka
We previously reported that a shallow circumpapillary retinal nerve fiber layer (cpRNFL) peak angle as measured by optical coherence tomography (OCT) suggests the temporal retina is stretched around the optic disc from the papillo-macular bundle (Yamashita T et al. Investigative Ophthalmol Vis Sci 2013). The purpose of the current study was to investigate the relationship between CorvisST tonometry (CST) corneal measurements, axial length (AL) and the change in OCT-measured cpRNFL peak angle, in young healthy subjects...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337056/normative-values-and-contralateral-comparison-of-anterior-chamber-parameters-measured-by-pentacam-and-its-correlation-with-corneal-biomechanical-factors
#19
Mohammad Reza Sedaghat, Vahid Mohammad Zadeh, Kaveh Fadakar, Sakineh Kadivar, Mojtaba Abrishami
PURPOSE: To evaluate the normative values of anterior chamber parameters measured by Pentacam and corneal hysteresis (CH) and corneal resistance factor (CRF) measured by Ocular Response Analyzer (ORA) and their relationship. METHODS: In an observational cross-sectional study, patients aged 18-35 years were included. Exclusion criteria were history of any intraocular or corneal disease, anomaly or surgery; hyperopic spherical refraction more than +3, and myopic spherical refraction less than -5...
January 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28320557/study-of-light-scattering-using-c-quant-%C3%A2-in-patients-with-fuchs-endothelial-dystrophy-a-pilot-study
#20
B Castaño-Martín, J Gros-Otero, J Martínez, M Teus
OBJECTIVE: The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters. MATERIALS AND METHODS: The values of light scattering were measured by C-Quant(®) (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema...
March 17, 2017: Archivos de la Sociedad Española de Oftalmología
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