keyword
MENU ▼
Read by QxMD icon Read
search

Topical pain creams

keyword
https://www.readbyqxmd.com/read/27888448/a-randomized-single-blind-trial-of-clobetasol-propionate-0-05-cream-under-silicone-dressing-occlusion-versus-intra-lesional-triamcinolone-for-treatment-of-keloid
#1
Norazirah Md Nor, Rasimah Ismail, Adawiyah Jamil, Shamsul Azhar Shah, Farah Hani Imran
BACKGROUND AND OBJECTIVE: Keloid is conventionally treated with intra-lesional (IL) triamcinolone, which is highly operator dependent and has its own adverse effects. Topical steroid and silicone dressings are a patient friendly and non-invasive treatment alternative. We therefore sought to determine the efficacy and safety of topical clobetasol propionate (Dermovate(®)) 0.05% cream under occlusion with Mepiform(®) silicone dressing compared to IL triamcinolone in the treatment of keloid...
November 25, 2016: Clinical Drug Investigation
https://www.readbyqxmd.com/read/27869649/randomized-trial-of-calcipotriol-combined-with-5-fluorouracil-for-skin-cancer-precursor-immunotherapy
#2
Trevor J Cunningham, Mary Tabacchi, Jean-Pierre Eliane, Sara Moradi Tuchayi, Sindhu Manivasagam, Hengameh Mirzaalian, Ahu Turkoz, Raphael Kopan, Andras Schaffer, Arturo P Saavedra, Michael Wallendorf, Lynn A Cornelius, Shadmehr Demehri
BACKGROUND: Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments. Thymic stromal lymphopoietin (TSLP) is an epithelium-derived cytokine that induces a robust antitumor immunity in barrier-defective skin. Here, we investigated the efficacy of calcipotriol, a topical TSLP inducer, in combination with 5-fluorouracil (5-FU) as an immunotherapy for actinic keratosis...
November 21, 2016: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27828835/prospective-evaluation-of-fractional-co2-laser-treatment-of-mature-burn-scars
#3
Sigrid Blome-Eberwein, Christina Gogal, Michael J Weiss, Deborah Boorse, Patrick Pagella
The authors conducted a prospective study of fractional CO2 laser treatment of mature burn scars, comparing objective and subjective scar measurements evaluating at least one treatment and one control scar on the same patient pre- and post treatments. After institutional review board approval, burn survivors with mature blatant burn scars were invited to enter the study. A series of three fractional CO2 laser treatments was performed in an office setting, using topical anesthetic cream, at 40 to 90 mJ, 100 to 150 spots per cm...
November 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27803240/self-administered-interventions-for-anogenital-warts-in-immunocompetent-patients-a-systematic-review-and-meta-analysis
#4
Ricardo Niklas Werner, Lukas Westfechtel, Corinna Dressler, Alexander Nast
BACKGROUND: Anogenital warts (AGWs, condylomata acuminata) are among the most common STIs and may severely impact quality of life (QoL). Available treatment options are characterised by a high proportion of non-responders and recurrences. OBJECTIVE: To systematically review and meta-analyse the available evidence from randomised controlled trials (RCTs) on topical treatments for AGWs considering short-term and long-term efficacy, effects on QoL and adverse events (AE)...
November 1, 2016: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/27792244/breastfeeding-for-procedural-pain-in-infants-beyond-the-neonatal-period
#5
REVIEW
Denise Harrison, Jessica Reszel, Mariana Bueno, Margaret Sampson, Vibhuti S Shah, Anna Taddio, Catherine Larocque, Lucy Turner
BACKGROUND: Randomised controlled trials (RCTs) show that breastfeeding newborn infants during painful procedures reduces pain. Mechanisms are considered to be multifactorial and include sucking, skin-to-skin contact, warmth, rocking, sound and smell of the mother, and possibly endogenous opiates present in the breast milk. OBJECTIVES: To determine the effect of breastfeeding on procedural pain in infants beyond the neonatal period (first 28 days of life) up to one year of age compared to no intervention, placebo, parental holding, skin-to-skin contact, expressed breast milk, formula milk, bottle feeding, sweet-tasting solutions (e...
October 28, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27775307/-balanitis-xerotica-obliterans-underdiagnosed-pathology-of-clinical-relevance
#6
E Calleja Aguayo, A E Hernández Calvarro, C Marhuenda Irastorza
OBJECTIVES: Balanitis xerotica obliterans (BXO) is a chronic inflamatory disease, a genital form of Lichen Sclerosus in males. MATERIAL AND METHODS: This retrospective and descriptive analysis was carried out by rewiew of the medical records of boys who underwent circumcision from April 2013 to April 2014. The study group consisted of boys that were circumcised due it persistant phimosis at 4 years of age, urinary symptoms or painful erection. The histopathological examination was performed only in patients with clinical suspicion of BXO...
July 20, 2015: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27757050/new-topical-treatment-of-vulvodynia-based-on-the-pathogenetic-role-of-cross-talk-between-nociceptors-immunocompetent-cells-and-epithelial-cells
#7
J M Keppel Hesselink, D J Kopsky, N Sajben
Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, somewhat neglected element of the vulvodynia pathogenesis: the cross talk between the nerve endings of nociceptors, the adjacent immunocompetent cells, and vaginal epithelial cells. Insight into this cross talk during a pathogenic condition supports the treatment of vulvodynia with topical (compounded) creams...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27719777/a-literature-review-on-the-practice-of-placentophagia
#8
Rachel Joseph, Marissa Giovinazzo, Megan Brown
Placentophagia (consuming the placenta) has historically not been a common practice among humans. Over the past few decades the practice has gained attention as more women, particularly educated, middle-class, White American women, choose to partake in this practice. Purported benefits of placentophagia include pain relief, increased breast milk production, and decreased risk of postpartum depression; however, there is a lack of evidence to support these claims. The placenta can be consumed raw, cooked, or encapsulated; it can be used for keepsakes; or it can be used to make topical applications such as dermatologic creams and hair-growth products...
October 2016: Nursing for Women's Health
https://www.readbyqxmd.com/read/27673139/poster-388-improvement-in-pain-control-in-complex-regional-pain-syndrome-treated-with-buprenorphine-patch-and-topical-compounding-cream-containing-ketamine-and-clonidine-a-case-series
#9
Robert E Kent, Zahra Kent, Joanna Q Hannah, Tarik Ksaibati
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27633647/comparison-of-topical-tacrolimus-and-clobetasol-in-the-management-of-symptomatic-oral-lichen-planus-a-double-blinded-randomized-clinical-trial-in-sri-lanka
#10
Pilana Vithanage Kalani Shihanika Hettiarachchi, Ruvini Manjula Hettiarachchi, Ruwan Duminda Jayasinghe, Mohaideen Sitheeque
AIM: Oral lichen planus (OLP) is a common, chronic inflammatory disease of the oral mucosa. Although several studies have shown the efficacy of different treatment modalities, a definitive cure has not yet been established. The present trial compares the effectiveness of topically-applied clobetasol and tacrolimus in the symptomatic management of OLP. METHODS: A randomized, comparative, double-blind study with 68 patients (43 females, 25 males; mean age: 46.76 years) was undertaken...
September 15, 2016: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/27598444/fractional-laser-assisted-topical-imiquimod-5-cream-treatment-for-recalcitrant-common-warts-in-children-a-pilot-study
#11
Sung-Min Park, Gun-Wook Kim, Je-Ho Mun, Margaret Song, Hoon-Soo Kim, Byung-Soo Kim, Moon-Bum Kim, Hyun-Chang Ko
BACKGROUND: Conventional treatments for warts like cryotherapy are limited by the pain during procedures, especially in pediatric patients. Imiquimod is a topical immune response modifier, but the thick stratum corneum of common warts prevents drug permeation through skin. OBJECTIVE: To evaluate the efficacy and safety of fractional laser/topical 5% imiquimod cream for the treatment of warts in children. METHODS: Eleven pediatric patients with multiple recalcitrant common warts were included...
September 2, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27595728/effect-of-topical-anesthesia-with-lidocaine-prilocaine-emla-cream-and-local-pressure-on-pain-during-infiltration-injection-for-maxillary-canines-a-randomized-double-blind-clinical-trial
#12
Amin S Milani, Vahid Zand, Amir A Abdollahi, Mohammad Froughreyhani, Parvin Zakeri-Milani, Mohammad A Jafarabadi
OBJECTIVES: This study compared the effect of local pressure and topical lidocaine-prilocaine (EMLA) cream on pain during infiltration injection for maxillary canine teeth. MATERIALS AND METHODS: A total of 140 volunteer students participated in this split-mouth design randomized clinical trial. The subjects were randomly divided into four groups (n = 35). Before administration of anesthesia, in each group, one side was randomly selected as the experimental and the opposite side as the control...
2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/27575957/interventions-for-men-and-women-with-their-first-episode-of-genital-herpes
#13
REVIEW
Rachel Heslop, Helen Roberts, Deralie Flower, Vanessa Jordan
BACKGROUND: Genital herpes is incurable, and is caused by the herpes simplex virus (HSV). First-episode genital herpes is the first clinical presentation of herpes that a person experiences. Current treatment is based around viral suppression in order to decrease the length and severity of the episode. OBJECTIVES: To determine the effectiveness and safety of the different existing treatments for first-episode genital herpes on the duration of symptoms and time to recurrence...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27530588/the-effect-of-eutectic-mixture-of-local-anesthesia-cream-emla-on-satisfaction-pain-and-nausea-vomiting-of-patients-undergoing-gastro-intestinal-endoscopy-a-randomized-clinical-trial-comparing-emla-cream-and-gel-lidocaine-gel-and-spray-and-placebo
#14
Jafar Nasiri, Amin Ahmadi, Forouzan Ganji
BACKGROUND & OBJECTIVES: Esophagogastroduodenoscopy is a valuable diagnostic method for the treatment of various diseases that has found a wonderful application in recent years. Yet, controlling patients' pain and nausea is a fundamental factor to increase patient satisfaction, reduce patients' discomfort, and increase the patient's cooperation. Therefore, this study aimed to assess the efficacy of Eutectic Mixture of Local Anesthesia (EMLA) cream and gel, as a topical pharyngeal anesthetic on patients' pharyngeal pain, nausea/vomiting, and satisfaction, in comparison with lidocaine gel and spray and placebo...
2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27500801/analgesic-efficacy-of-equimolar-50-nitrous-oxide-oxygen-gas-premix-kalinox%C3%A2-as-compared-with-a-5-eutectic-mixture-of-lidocaine-prilocaine-emla%C3%A2-in-chronic-leg-ulcer-debridement
#15
Juerg Traber, Ulrike Held, Maria Signer, Tobias Huebner, Stefan Arndt, Thomas A Neff
Chronic foot and leg ulcers are a common health problem worldwide. A mainstay of chronic ulcer therapy is sharp mechanical wound debridement requiring potent analgesia. In this prospective, controlled, single-centre, crossover design study, patients were assigned to either the administration of topical analgesia with 5% lidocaine/prilocaine cream or the inhalation of an analgesic 50% N2 O/O2 gas premix. Primary outcome parameter was level of pain at maximum wound depth during debridement as measured by a visual analogue scale...
August 8, 2016: International Wound Journal
https://www.readbyqxmd.com/read/27479625/treating-painful-diabetic-peripheral-neuropathy-an-update
#16
Matthew J Snyder, Lawrence M Gibbs, Tammy J Lindsay
Painful diabetic peripheral neuropathy occurs in approximately 25% of patients with diabetes mellitus who are treated in the office setting and significantly affects quality of life. It typically causes burning pain, paresthesias, and numbness in a stocking-glove pattern that progresses proximally from the feet and hands. Clinicians should carefully consider the patient's goals and functional status and potential adverse effects of medication when choosing a treatment for painful diabetic peripheral neuropathy...
August 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27419471/clinical-effect-of-ablative-fractional-laser-assisted-topical-anesthesia-on-human-skin-a-randomized-pilot-study
#17
Tian Tian, Yaojia Luo, Tianling Jiang, Yuxi Dong, Aijiao Yu, Hongduo Chen, Xinghua Gao, Yuanhong Li
BACKGROUND AND OBJECTIVES: Most topical medications need a long time to penetrate into the skin owing to the stratum corneum (SC) barrier. The fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser has the ability to disrupt the SC and assist in the delivery of topical drugs to penetrate into the skin. This study was intended to determine whether pretreatment with a painless fractional Er:YAG laser could assist transdermal delivery of topical anesthesia. MATERIALS AND METHODS: In 22 healthy female subjects, three 4 × 3 cm regions on the right forearm were randomized to: fractional laser plus topical lidocaine cream (Group LaserAnes), sham irradiation plus topical anesthesia (Group Anes), and sham irradiation plus sham anesthesia (Group Con)...
August 5, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27377616/comparison-of-lidocaine-tetracaine-cream-and-lidocaine-prilocaine-cream-for-local-anaesthesia-during-laser-treatment-of-acne-keloidalis-nuchae-and-tattoo-removal-results-of-two-randomized-controlled-trials
#18
K Greveling, E P Prens, N Ten Bosch, M van Doorn
BACKGROUND: Pain is a common adverse effect during dermatological laser procedures. Currently, no standard topical anaesthetic cream exists for deeper dermal laser procedures. OBJECTIVE: To compare the efficacy of lidocaine/tetracaine cream and lidocaine/prilocaine cream in reducing self-reported pain during deeper dermal laser treatments of acne keloidalis nuchae (AKN) and tattoos. METHODS: We conducted two randomized, double-blind, controlled clinical trials with intra-patient, split-lesion design: Study A in patients with AKN (n=15), and Study B in patients with black tattoos (n=15)...
July 5, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27375183/plum-blossom-needling-promoted-ppix-fluorescence-intensity-from-5-aminolevulinic-acid-in-porcine-skin-model-and-patients-with-actnic-keratosis
#19
Jia Chen, Yunfeng Zhang, Peiru Wang, Bo Wang, Guolong Zhang, Xiuli Wang
BACKGROUND AND OBJECTIVES: Plum-blossom needling might enhance transdermal penetration of topically applied drugs by creating vertical channels. The purpose of this study was to evaluate drug delivery assisted by plum-blossom needling comparing with CO2 laser ablative fractional resurfacing (AFR) using 5-aminolevulinic acid (5-ALA), a porphyrin precursor, as a test drug. MATERIALS AND METHODS: Ex vivo porcine skin was treated with plum-blossom needle(HWATO, Suzhou medical supplies factory Co...
September 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27354889/benzocaine-lidocaine-tetracaine-cream-report-of-corneal-damage-and-review
#20
Metavee Boonsiri, Katherine C Marks, Chérie M Ditre
Practitioners are increasingly using topical anesthetics in the field of dermatology. Application of topical anesthetics prior to performing dermatologic procedures has proven to decrease pain and discomfort associated with these procedures. Despite the prevalent use of topical anesthetics, there are few standard guidelines for about which products provide optimal and safest use. Adverse events are often correlated with improper application of topical anesthetics. A few case reports have cited adverse events related to the use of compounded products that the United States Food and Drug Administration has not approved, such as benzocaine, lidocaine, tetracaine...
March 2016: Journal of Clinical and Aesthetic Dermatology
keyword
keyword
32437
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"