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https://www.readbyqxmd.com/read/28823132/a-short-term-supranutritional-vitamin-e-supplementation-alleviated-respiratory-alkalosis-but-did-not-reduce-oxidative-stress-in-heat-stressed-pigs
#1
Fan Liu, Pietro Celi, Surinder Singh Chauhan, Jeremy James Cottrell, Brian Joseph Leury, Frank Rowland Dunshea
Objective: Heat stress (HS) triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. Methods: A total of 24 pigs were given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet for 14 d, then exposed to thermoneutral (TN; 20°C, 45% humidity) or HS (35°C, 35-45% humidity, 8 h daily) conditions for 7 d...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28822459/oral-propylene-glycol-modifies-follicular-fluid-and-gene-expression-profiles-in-cumulus-oocyte-complexes-and-embryos-in-feed-restricted-heifers
#2
G Gamarra, C Ponsart, S Lacaze, F Nuttinck, A Cordova, P Mermillod, B Marquant-Le Guienne, D Monniaux, P Humblot, A A Ponter
Dietary supplementation with propylene glycol (PG) increases in vitro production of high-quality embryos in feed-restricted heifers. The aim of the present study was to evaluate the effects of PG in feed-restricted heifers on follicular fluid insulin and insulin-like growth factor (IGF) 1 concentrations, expression of IGF system genes in oocytes and cumulus cells and the expression of selected genes in blastocysts. Feed-restricted (R) heifers were drenched with water or PG during induced oestrous cycles (400mL of PG or water/drench, daily drenching at 1600 hours for the first 9 days of the oestrous cycle)...
August 21, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28822065/the-inflammatory-potential-of-dietary-manganese-in-a-cohort-of-elderly-men
#3
Jacob K Kresovich, Catherine M Bulka, Brian T Joyce, Pantel S Vokonas, Joel Schwartz, Andrea A Baccarelli, Elizabeth A Hibler, Lifang Hou
Manganese is an essential nutrient that may play a role in the production of inflammatory biomarkers. We examined associations between estimated dietary manganese intake from food/beverages and supplements with circulating biomarkers of inflammation. We further explored whether estimated dietary manganese intake affects DNA methylation of selected genes involved in the production of these biomarkers. We analyzed 1023 repeated measures of estimated dietary manganese intakes and circulating blood inflammatory biomarkers from 633 participants in the Normative Aging Study...
August 18, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28821445/effects-of-the-prebiotic-mannan-oligosaccharide-on-the-stress-response-of-feed-deprived-zebrafish-danio-rerio
#4
Mohammad Navid Forsatkar, Mohammad Ali Nematollahi, Gholamreza Rafiee, Hamid Farahmand, Christian Lawrence
Feed deprivation has deleterious effects on fish behavior and stress physiology which may susceptible them to disease outbreak. Functional ingredients in diets may substantially impact the physiology and stress responses of host organisms. Here, we hypothesized that the administration of a dietary prebiotic might attenuate the negative influences of feed deprivation on the behavioral profile of anxiety and physiological responses to stress in zebrafish (Danio rerio). Fish were fed with either basal or mannan-oligosaccharide supplemented (0...
August 15, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28821318/consumption-of-an-acid-protease-derived-from-aspergillus-oryzae-causes-bifidogenic-effect-in-rats
#5
Yongshou Yang, Akane Iwamoto, Thanutchaporn Kumrungsee, Yukako Okazaki, Manabu Kuroda, Shotaro Yamaguchi, Norihisa Kato
A marked elevation in the abundance of Bifidobacterium was found in the cecum of rats that were fed a high-fat diet supplemented with an Amano protease preparation (derived from Aspergillus oryzae). The protease preparation contains several digestive enzymes, including acid protease (AcP), alkaline protease, and amylase. We hypothesized that the elevation in the abundance of Bifidobacterium by Amano protease preparation is associated with the digestive enzymes involved in the protease preparation. To test this hypothesis, this study was conducted to investigate if such bifidogenic effect is because of the AcP...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821315/starch-entrapped-microsphere-fibers-improve-bowel-habit-but-do-not-exhibit-prebiotic-capacity-in-those-with-unsatisfactory-bowel-habits-a-phase-i-randomized-double-blind-controlled-human-trial
#6
Heather E Rasmussen, Bruce Hamaker, Kumar B Rajan, Ece Mutlu, Stefan J Green, Michael Brown, Amandeep Kaur, Ali Keshavarzian
Approximately one-third of individuals in the United States experience unsatisfactory bowel habits, and dietary intake, especially one low in fiber, could be partly responsible. We hypothesized that intake of a fermentable fiber (starch-entrapped microspheres, SM) that has a delayed, slow fermentation profile in vitro would improve bowel habit while exhibiting prebiotic capacity in those with self-described unsatisfactory bowel habits, all with minimal adverse effects. A total of 43 healthy volunteers completed a 3-month, double-blind, parallel-arm randomized clinical trial to assess the ability of a daily dose (9 or 12 g) of SM vs psyllium (12 g) to improve bowel habit, including stool consistency and frequency, and modify gut milieu through changes in stool microbiota and short-chain fatty acids while remaining tolerable through minimal gastrointestinal symptoms...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821245/ambient-ultraviolet-radiation-exposure-and-hepatocellular-carcinoma-incidence-in-the-united-states
#7
Trang VoPham, Kimberly A Bertrand, Jian-Min Yuan, Rulla M Tamimi, Jaime E Hart, Francine Laden
BACKGROUND: Hepatocellular carcinoma (HCC), the most commonly occurring type of primary liver cancer, has been increasing in incidence worldwide. Vitamin D, acquired from sunlight exposure, diet, and dietary supplements, has been hypothesized to impact hepatocarcinogenesis. However, previous epidemiologic studies examining the associations between dietary and serum vitamin D reported mixed results. The purpose of this study was to examine the association between ambient ultraviolet (UV) radiation exposure and HCC risk in the U...
August 18, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28821244/the-effect-of-dietary-bacterial-organic-selenium-on-growth-performance-antioxidant-capacity-and-selenoproteins-gene-expression-in-broiler-chickens
#8
A M Dalia, T C Loh, A Q Sazili, M F Jahromi, A A Samsudin
BACKGROUND: Selenium (Se) is an essential trace mineral in broilers, which has several important roles in biological processes. Organic forms of Se are more efficient than inorganic forms and can be produced biologically via Se microbial reduction. Hence, the possibility of using Se-enriched bacteria as feed supplement may provide an interesting source of organic Se, and benefit broiler antioxidant system and other biological processes. The objective of this study was to examine the impacts of inorganic Se and different bacterial organic Se sources on the performance, serum and tissues Se status, antioxidant capacity, and liver mRNA expression of selenoproteins in broilers...
August 18, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28821087/in-vivo-antihyperlipidemic-and-antioxidant-activity-of-porphyran-in-hyperlipidemic-mice
#9
Xiaomei Wang, Weida Li, Li Xiao, Chundong Liu, Huimin Qi, Zhongshan Zhang
The hypolipidemic and antioxidant effects of porphyran from the red algae Porphyra haitanensis as a dietary supplement were evaluated in mice. The levels of serum TC, TG and LDL-C in MP group increased significantly (p<0.05 or p<0.01) by 28.5%, 29.4% and 33.5% compared with the model group. These significant rises were accompanied by significant declines of plasma HDL-C by 21.6% compared with the model group. In addition, the liver content of malondialdehyde significantly decreased, while the superoxide dismutase, catalase, glutathione peroxidase activities significantly increased...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820428/pharmacokinetic-analysis-of-an-oral-multicomponent-joint-dietary-supplement-phycox-%C3%A2-in-dogs
#10
Stephanie E Martinez, Ryan Lillico, Ted M Lakowski, Steven A Martinez, Neal M Davies
Despite the lack of safety, efficacy and pharmacokinetic (PK) studies, multicomponent dietary supplements (nutraceuticals) have become increasingly popular as primary or adjunct therapies for clinical osteoarthritis in veterinary medicine. Phycox(®) is a line of multicomponent joint support supplements marketed for joint health in dogs and horses. Many of the active constituents are recognized anti-inflammatory and antioxidant agents. Due to a lack of PK studies in the literature for the product, a pilot PK study of select constituents in Phycox(®) was performed in healthy dogs...
August 18, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28820083/threonine-deficiency-decreased-intestinal-immunity-and-aggravated-inflammation-associated-with-nf-%C3%AE%C2%BAb-and-target-of-rapamycin-signalling-pathways-in-juvenile-grass-carp-ctenopharyngodon-idella-after-infection-with-aeromonas-hydrophila
#11
Yu-Wen Dong, Wei-Dan Jiang, Yang Liu, Pei Wu, Jun Jiang, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Yong-An Zhang, Xiao-Qiu Zhou, Lin Feng
This study aimed to investigate the impacts of dietary threonine on intestinal immunity and inflammation in juvenile grass carp. Six iso-nitrogenous semi-purified diets containing graded levels of threonine (3·99-21·66 g threonine/kg) were formulated and fed to fishes for 8 weeks, and then challenged with Aeromonas hydrophila for 14 d. Results showed that, compared with optimum threonine supplementation, threonine deficiency (1) decreased the ability of fish against enteritis, intestinal lysozyme activities (except in the distal intestine), acid phosphatase activities, complement 3 (C3) and C4 contents and IgM contents (except in the proximal intestine (PI)), and it down-regulated the transcript abundances of liver-expressed antimicrobial peptide (LEAP)-2A, LEAP-2B, hepcidin, IgZ, IgM and β-defensin1 (except in the PI) (P<0·05); (2) could up-regulate intestinal pro-inflammatory cytokines TNF-α, IL-1β, IL-6, IL-8 and IL-17D mRNA levels partly related to NF-κB signalling; (3) could down-regulate intestinal anti-inflammatory cytokine transforming growth factor (TGF)-β1, TGF-β2, IL-4/13A (not IL-4/13B) and IL-10 mRNA levels partly by target of rapamycin signalling...
July 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28820082/high-dose-b-vitamin-supplements-and-risk-for-age-related-cataract-a-population-based-prospective-study-of-men-and-women
#12
Jinjin Z Selin, Birgitta E Lindblad, Matteo Bottai, Ralf Morgenstern, Alicja Wolk
Previous studies that have investigated the association between B-vitamin supplement use and risk for cataract yield conflicting results. The aim of this study was to examine the association between use of high-dose B-vitamin supplements (approximately 10 times recommended daily intake) and risk for age-related cataract in a population-based prospective study of 13 757 women from the Swedish Mammography Cohort and 22 823 men from the Cohort of Swedish Men. Dietary supplement use and potential confounders were assessed using a questionnaire at baseline...
July 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28819559/growth-inhibitory-efficacy-of-natural-products-in-a-model-for-triple-negative-molecular-subtype-of-clinical-breast-cancer
#13
Nitin Telang
Global gene expression profiling identifies predictive and prognostic biomarkers and rationalizes breast cancer subtype-targeted treatment. The Anthracyclin/Taxol and survival pathway specific small molecular inhibitors, constitute current treatment options. These options are associated with acquired tumor resistance and emergence of drug-resistant cancer stem cells. Dietary supplements and constitutive bioactive phytochemicals with relatively low systemic toxicity may provide testable alternatives for current therapy...
September 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28818751/nutritional-modulation-of-intestinal-drug-metabolizing-cytochrome-p450-by-butyrate-of-different-origin-in-chicken
#14
Anna Kulcsár, Gábor Mátis, Andor Molnár, Janka Petrilla, László Wágner, Hedvig Fébel, Ferenc Husvéth, Károly Dublecz, Zsuzsanna Neogrády
Intestinal cytochrome P450 (CYP) enzymes play key role in the first pass metabolism of orally ingested xenobiotics, providing a primary metabolic barrier, being of special importance in maintaining animal health and production. This study was aimed to investigate how intestinal drug-metabolizing CYPs can be modulated by nutritional factors in broiler chicken. We investigated the effects of the natural growth promoter (n-)butyrate of different origin (feed supplementation of protected or non-protected forms and/or inducing caecal microbial production by supporting higher level of dietary non-starch polysaccharides [NSP]) on the activity of duodenal CYPs...
August 1, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28818673/1-25-dihydroxyvitamin-d3-induces-brain-proteomic-changes-in-cuprizone-mice-during-remyelination-involving-calcium-proteins
#15
Eystein Oveland, Agnes Nystad, Frode Berven, Kjell-Morten Myhr, Øivind Torkildsen, Stig Wergeland
Dietary supplementation of vitamin D is commonly recommended to patients with multiple sclerosis. We recently found that high-dose of the hormonally active 1,25-dihydroxyvitamin-D3 (1,25D) promotes myelin repair in the cuprizone model for de- and remyelination. In the present study, we quantified 5062 proteins, of which 125 were differentially regulated in brain tissue from 1,25D treated mice during remyelination, compared to placebo. Proteins upregulated in the early remyelination phase were involved in calcium binding, e...
August 14, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28818086/mediterranean-diet-folic-acid-and-neural-tube-defects
#16
REVIEW
Maximilian Fischer, Mauro Stronati, Marcello Lanari
The Mediterranean diet has been for a very long time the basis of food habits all over the countries of the Mediterranean basin, originally founded on rural models and low consumption of meat products and high-fat/high-processed foods. However, in the modern era, the traditional Mediterranean diet pattern is now progressively eroding due to the widespread dissemination of the Western-type economy, life-style, technology-driven culture, as well as the globalisation of food production, availability and consumption, with consequent homogenisation of food culture and behaviours...
August 17, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28817948/effects-of-dietary-supplementation-of-resveratrol-on-performance-egg-quality-yolk-cholesterol-and-antioxidant-enzyme-activity-of-laying-hens
#17
Z H Feng, J G Gong, G X Zhao, X Lin, Y C Liu, K W Ma
1. This experiment was conducted to evaluate the effects of dietary supplementation of resveratrol on laying performance, egg quality, egg yolk cholesterol and antioxidant enzyme activities of laying hens. 2. A total of 360 Beijing PINK-1 laying hens (60 weeks old) were randomly distributed among 5 dietary treatments, each of which included 6 replicates of 12 hens. Dietary treatments were basal diet supplemented with 0 (control), 0.5, 1.0, 2.0 and 4.0 g/kg diet resveratrol. The study lasted for 9 weeks including 1 week of adaptation and 8 weeks of the main experimental period...
August 18, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28816876/osteoporotic-thoracolumbar-fractures-how-are-they-different-classification-and-treatment-algorithm
#18
Shanmuganathan Rajasekaran, Rishi M Kanna, Klaus J Schnake, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, Cumhur Oner
Osteoporotic vertebral fractures constitute at least 50% of the osteoporotic fractures that happen worldwide. Occurrence of osteoporotic fractures make the elderly patient susceptible for further fractures and increases the morbidity due to kyphosis and pain; the mortality risk is also increased in these patients. Most fractures occur in the thoracic and thoracolumbar region and are often stable. Different descriptive and prognostic classification systems have been described, but none are universally accepted...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28816555/chemical-utilization-of-albizia-lebbeck-leaves-for-developing-protein-concentrates-as-a-dietary-supplement
#19
Lutful Haque Khan, V K Varshney
In search of nonconventional sources of protein to combat widespread malnutrition, the possibility of developing a protein concentrate as an alternative dietary supplement from abundantly available yet poorly valorized leaves of Albizia lebbeck (siris) was examined. A process for recovery of leaf protein concentrate (LPC) from these leaves was optimized and applied for isolation of LPCs from lower, middle, and upper canopies of the tree. The optimized conditions (leaves to water 1:9, coagulation at pH 4.0 using 1 N citric acid at 90°C for 11 minutes) afforded LPCs containing protein 37...
August 17, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28816548/dietary-supplementation-with-virgin-coconut-oil-improves-lipid-profile-and-hepatic-antioxidant-status-and-has-potential-benefits-on-cardiovascular-risk-indices-in-normal-rats
#20
Ademola C Famurewa, Chima A Ekeleme-Egedigwe, Sophia C Nwali, Ngozi N Agbo, Joy N Obi, Goodness C Ezechukwu
Research findings that suggest beneficial health effects of dietary supplementation with virgin coconut oil (VCO) are limited in the published literature. This study investigated the in vivo effects of a 5-week VCO-supplemented diet on lipid profile, hepatic antioxidant status, hepatorenal function, and cardiovascular risk indices in normal rats. Rats were randomly divided into 3 groups: 1 control and 2 treatment groups (10% and 15% VCO-supplemented diets) for 5 weeks. Serum and homogenate samples were used to analyze lipid profile, hepatorenal function markers, hepatic activities of antioxidant enzymes, and malondialdehyde level...
August 17, 2017: Journal of Dietary Supplements
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