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https://www.readbyqxmd.com/read/28092783/pulmonary-emboli-cardiac-arrest-with-cpr-complication-liver-laceration-and-massive-abdominal-bleed-a-case-report
#1
John Lundqvist, Jan G Jakobsson
INTRODUCTION: Massive pulmonary emboli may cause right ventricular failure and backward stasis with parenchymal organ swelling thus increasing the risk for laceration, e.g. if CPR is needed. PRESENTATION OF CASE: A 28-year-old Colombian female with no medical history but taking contraceptive pills and having had a recent longer flight was admitted to Danderyds hospital Emergency Department because of respiratory failure. She developed cardiac arrest in the emergence department following the emergent diagnosis of pulmonary emboli...
January 3, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28088209/pulmonary-embolism-in-non-brain-tumor-patients-after-surgery-a-retrospective-study-in-china
#2
Ren-Xiong Chen, Hong-Zhi Wang, Jun Dong, Hong Ren, Xiao-Jie Chen, Jia-Xuan Xu, Yong Yang, Guo-Dong Wang
BACKGROUND: The incidence rate of pulmonary emboli (PE) is high in tumor patients; however, the morbidity and mortality associated with the development of PE after tumor surgery are unknown. We studied the clinical profiles and outcomes of patients with PE after non-brain tumor surgery. METHODS: We retrospectively screened 55,967 patients who underwent non-brain tumor surgery at the Peking University Cancer Hospital from January 2008 to June 2015. Among them, 76 patients who were diagnosed with PE were enrolled in our study...
January 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28087184/clinical-characteristics-of-ruptured-distal-middle-cerebral-artery-aneurysms-review-of-the-literature
#3
REVIEW
Keiji Tsutsumi, Tetsuyoshi Horiuchi, Alhusain Nagm, Yasuyuki Toba, Kazuhiro Hongo
Middle cerebral artery (MCA) aneurysms usually arise at the primary MCA bifurcation or trifurcation. Distal MCA aneurysms are rarely considered as sources of aneurysmal subarachnoid hemorrhage (SAH). It has been reported that ruptured distal MCA aneurysms are associated with head trauma, neoplastic emboli, arterial dissection, or bacterial infection. We experienced five cases of ruptured distal MCA aneurysms and evaluated their clinical characteristics. Retrospective analysis of aneurysmal SAH at Kobayashi Neurosurgical Neurological Hospital was performed from January, 2004 to December, 2014...
January 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28077455/symptomatic-carotid-occlusion-is-frequently-associated-with-microembolization
#4
Ava L Liberman, Ali Zandieh, Caitlin Loomis, Jonathan M Raser-Schramm, Christina A Wilson, Jose Torres, Koto Ishida, Swaroop Pawar, Rebecca Davis, Michael T Mullen, Steven R Messé, Scott E Kasner, Brett L Cucchiara
BACKGROUND AND PURPOSE: Symptomatic carotid artery disease is associated with significant morbidity and mortality. The pathophysiologic mechanisms of cerebral ischemia among patients with carotid occlusion remain underexplored. METHODS: We conducted a prospective observational cohort study of patients hospitalized within 7 days of ischemic stroke or transient ischemic attack because of ≥50% carotid artery stenosis or occlusion. Transcranial Doppler emboli detection was performed in the middle cerebral artery ipsilateral to the symptomatic carotid...
January 11, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28070749/an-automated-microemboli-detection-and-classification-system-using-backscatter-rf-signals-and-differential-evolution
#5
Karim Ferroudji, Nabil Benoudjit, Ayache Bouakaz
Embolic phenomena, whether air or particulate emboli, can induce immediate damages like heart attack or ischemic stroke. Embolus composition (gaseous or particulate matter) is vital in predicting clinically significant complications. Embolus detection using Doppler methods have shown their limits to differentiate solid and gaseous embolus. Radio-frequency (RF) ultrasound signals backscattered by the emboli contain additional information on the embolus in comparison to the traditionally used Doppler signals...
January 9, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28069419/hyperbaric-oxygen-therapy-for-the-prevention-of-arterial-gas-embolism-in-food-grade-hydrogen-peroxide-ingestion
#6
Stephen M Hendriksen, Nicholas L Menth, Bjorn C Westgard, Jon B Cole, Joseph W Walter, Thomas C Masters, Christopher J Logue
Food grade hydrogen peroxide ingestion is a relatively rare presentation to the emergency department. There are no defined guidelines at this time regarding the treatment of such exposures, and providers may not be familiar with the potential complications associated with high concentration hydrogen peroxide ingestions. In this case series, we describe four patients who consumed 35% hydrogen peroxide, presented to the emergency department, and were treated with hyperbaric oxygen therapy. Two of the four patients were critically ill requiring intubation...
December 14, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28063201/relation-between-dynamic-change-of-red-cell-distribution-width-and-30-day-mortality-in-patients-with-acute-pulmonary-embolism
#7
Selçuk Yazıcı, Tuncay Kırış, Ufuk Sadık Ceylan, Sait Terzi, Ahmet Okan Uzun, Ayşe Emre, Kemal Yeşilçimen
Introduction and Objectives Recent studies suggest that an increase in red cell distribution width (RDW) levels have a better prognostic value than a single measurement. In the current study, we investigated the predictive value of increasing RDW levels for mortality in acute pulmonary emboli (APE) patients. Materials and Methods For the study, 199 APE patients who were hospitalized were enrolled. Patients were divided into three groups according to their admission and 24(th) hour RDW values. Patients for whom both RDW values normal were put in group 1 (normal); patients with admission RDW > 14...
January 7, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28062804/delayed-enhancing-lesions-after-coil-embolization-of-aneurysms-clinical-experience-and-benchtop-analyses
#8
Se Won Oh, Na Young Shin, Ho-Joon Lee, Byung Moon Kim, Dong Joon Kim
BACKGROUND: Foreign body emboli during endovascular treatment (EVT) may cause delayed enhancing lesions (DELs). OBJECTIVE: To report our experiences of this complication in patients treated for cerebral aneurysms and to investigate the cause of the lesions by benchtop analyses. METHODS: Three patients with DELs on MRI after EVT were retrospectively investigated. Unusual friction had occurred in the midst of coil delivery in two patients. The imaging findings, cause of the lesions due to the devices used for the procedure, treatment, and follow-up results were assessed...
January 6, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28056302/-expression-of-cd10-in-cancer-associated-fibroblasts-and-its-effect-on-initiation-and-progression-of-colorectal-carcinoma
#9
Y Zhu, J J Zheng, F Yang, Q Q Nie, Z L Zhu, H Deng
Objective: To study CD10 expression in cancer-associated fibroblasts (CAF) and related effect on colorectal cancer initiation and progression. Methods: A total of 226 surgical removed colorectal cancer specimens were collected with patient follow-up data. A panel of immunohistochemical markers(CD10, Ki-67, p53, cyclin D1 and β-catenin) were evaluated in carcinomas, adjacent adenomas and paired normal colorectal mucosa with correlation of clinicopathological parameters. Results: CD10 expression was not detected in the normal colorectal mucosa by immunohistochemistry...
December 8, 2016: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28051764/the-use-of-fibrin-sealant-during-non-emergency-surgery-a-systematic-review-of-evidence-of-benefits-and-harms
#10
Steven J Edwards, Fay Crawford, Michelle Helena van Velthoven, Andrea Berardi, George Osei-Assibey, Mariana Bacelar, Fatima Salih, Victoria Wakefield
BACKGROUND: Fibrin sealants are used in different types of surgery to prevent the accumulation of post-operative fluid (seroma) or blood (haematoma) or to arrest haemorrhage (bleeding). However, there is uncertainty around the benefits and harms of fibrin sealant use. OBJECTIVES: To systematically review the evidence on the benefits and harms of fibrin sealants in non-emergency surgery in adults. DATA SOURCES: Electronic databases [MEDLINE, EMBASE and The Cochrane Library (including the Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, the Health Technology Assessment database and the Cochrane Central Register of Controlled Trials)] were searched from inception to May 2015...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28045672/catheter-directed-fibrinolysis-of-submassive-pulmonary-embolism-after-ivc-filter-migration-to-renal-veins
#11
Kershaw V Patel, Jeffrey A Leef, John E Blair, Atman P Shah, Sandeep Nathan, Jonathan D Paul
A 76-year-old male presented with a submassive pulmonary embolism despite having an inferior vena cava (IVC) filter. Imaging demonstrated pulmonary artery emboli and a deep vein thrombosis in the left common femoral vein. Venography revealed the IVC filter with struts extending into the left and right renal veins. A new IVC filter was deployed below the prior filter. This case demonstrates IVC filter migration complicated by a submassive pulmonary embolism.
January 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28043147/microrna-182-targets-foxf2-to-promote-the-development-of-triple-negative-breast-cancer
#12
J Yu, W Shen, B Gao, H Zhao, J Xu, B Gong
To explore the function of microRNA-182 (miR-182) on MCF7 and MDA-MB-231 cells behaviors, and possible mechanisms of triple-negative breast cancer (TNBC) development. Totally, 30 TNBC patients were enrolled to investigate the correlation between miR-182 expression and TNBC clinical indicators. miR-182 expression in TNBC tissues was measured by qRT-PCR, followed by bioinformatics methods and luciferase reporter assay to investigate whether FOXF2 was a direct target of miR-182. Besides, miR-182 mimics were transfected into MCF7 cells while miR-182 inhibitor into MDA-MB-231 cells, followed by cell proliferation and migration detection...
January 3, 2017: Neoplasma
https://www.readbyqxmd.com/read/28040708/pulmonary-artery-sarcoma-mimicking-pulmonary-embolism-a-case-series
#13
Narat Srivali, Eunhee S Yi, Jay H Ryu
BACKGROUND: Pulmonary artery sarcoma (PAS) is a rare malignant neoplasm with an aggressive behavior and often difficult to distinguish from pulmonary thromboembolic disease. AIM: To assess the demographic, clinical, and radiological characteristics of PAS and clinical course. DESIGN AND METHODS: We retrospectively identified and analyzed all patients with PAS seen at Mayo Clinic in Rochester, Minnesota, between January 1, 1996 and July 31, 2015...
December 30, 2016: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28040384/circulatory-collapse-right-ventricular-dilatation-and-alveolar-dead-space-a-triad-for-the-rapid-diagnosis-of-massive-pulmonary-embolism
#14
Raúl J Gazmuri, Dimple J Patel, Rom Stevens, Shani Smith
A triad of circulatory collapse, right ventricular dilatation, and large alveolar dead space is proposed for the rapid diagnosis and treatment of massive pulmonary embolism. A 17year-old female on oral contraceptives collapsed at home becoming incoherent with shallow breathing. Paramedics initiated mechanical chest compression and transported the patient to our emergency department, arriving minimally responsive with undetectable blood pressure but having positive corneal reflexes and bradycardia with wide QRS...
December 16, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28035696/hydrophilic-polymer-vasculopathy-with-coinciding-pseudoxanthoma-elasticum-like-changes-in-an-amputated-toe
#15
Silvija P Gottesman, Elham Yousefi, Raavi Gupta
For the past decades, hydrophilic polymer gel coating have been widely used on endovascular devices to decrease friction and to aid with binding and delivering of medications in drug eluting stents. In the recent years, hydrophilic polymer emboli disease has been recognized as an iatrogenic adverse effect which has led to considerable morbidity and mortality of patients. This under-recognized embolic phenomenon now has reproducible pathognomonic histologic findings. Small to medium sized blood vessels are occluded with basophilic, amorphous, non-refractile, non-polarizable, whirled aggregates of foreign body material...
December 30, 2016: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28032166/periorbital-and-intraorbital-studies-of-the-terminal-branches-of-the-ophthalmic-artery-for-periorbital-and-glabellar-filler-placements
#16
Tanvaa Tansatit, Prawit Apinuntrum, Thavorn Phetudom
BACKGROUND: Filler injections for sunken upper eyelid correction and glabellar augmentation at the orbitoglabellar region need to be performed correctly. Precise knowledge of the emerging sites of all terminal branches of the ophthalmic artery is essential for these procedures to be conducted safely. METHODS: The terminal branches of the ophthalmic artery were studied in both periorbital and intraorbital dissections. The aim of this study was to verify the critical positions of the emerging sites at the orbital septum that may act as potential retrograde channels for filler emboli...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28031849/a-classical-case-of-non-bacterial-thrombotic-endocarditis-from-pancreatic-adenocarcinoma-presenting-as-multiple-strokes-myocardial-infarction-and-acute-limb-ischaemia
#17
Ching-Hui Sia, Joline Si Jing Lim, Kian Keong Poh, Tan Min Chin
Non-bacterial thrombotic endocarditis (NBTE) classically presents in the context of pancreatic adenocarcinomas. Echocardiography is useful to investigate for valvular vegetations, and institution of early treatment is crucial as this can be complicated by multiple systemic emboli, leading to significant morbidity or mortality in serious cases. Treatment options involve anticoagulation with unfractionated heparin, and the role of surgical intervention is unclear. In this report, we describe a classical case of a middle-aged lady with unresectable pancreatic adenocarcinoma who developed NBTE complicated by multiple systemic emboli...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031842/fatal-tumour-pulmonary-embolism
#18
Salim Rashid Masoud, Coenraad Frederik Nicolaas Koegelenberg, Abraham Christoffel van Wyk, Brian William Allwood
A 30-year-old female with no significant past medical history was referred to our facility with sudden onset of shortness of breath. She had a low clinical probability for pulmonary thromboembolism and a computed tomography angiogram showed enlarged pulmonary arteries but no in situ thrombi. She developed recurrent episodes of hypotension and hypoxia, and was transferred to the intensive care unit where she died despite active resuscitation. An autopsy revealed extensive lymphatic and pulmonary vascular tumour emboli as the immediate cause of death...
January 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28028830/retrospective-evaluation-of-postoperative-adverse-drug-events-in-patients-receiving-rivaroxaban-following-major-orthopedic-surgery-compared-to-standard-therapy-in-a-community-hospital
#19
Nicole E Cieri, Kristen Kusmierski, Cynthia Lackie, August Van Opdorp, Amany Hassan
STUDY OBJECTIVES: To evaluate the occurrence of bleeding and venous thromboembolic (VTE) events in patients receiving rivaroxaban, warfarin, or warfarin with the addition of enoxaparin during the immediate post-operative period following major orthopedic surgery. METHODS: Patients older than 18 years who received at least one dose of rivaroxaban the morning following surgery, adjusted dose warfarin, or adjusted dose warfarin with the addition of enoxaparin for VTE prophylaxis following major orthopedic surgery between October 1, 2011 and February 28, 2015 were included...
December 27, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/28028005/releasing-the-brakes-on-the-fibrinolytic-system-in-pulmonary-emboli-unique-effects-of-plasminogen-activation-and-%C3%AE-2-antiplasmin-inactivation
#20
Satish Singh, Aiilyan K Houng, Guy L Reed
BACKGROUND: -In patients with hemodynamically significant pulmonary embolism, physiologic fibrinolysis fails to dissolve thrombi acutely and recombinant tissue plasminogen activator (r-tPA) therapy may be required, despite its bleeding risk. To examine potential mechanisms, we analyzed the expression of key fibrinolytic molecules in experimental pulmonary emboli, assessed the contribution of α2-antiplasmin to fibrinolytic failure and compared the effects of plasminogen activation and α2-antiplasmin-inactivation on experimental thrombus dissolution and bleeding...
December 27, 2016: Circulation
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