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JOURNAL ARTICLE
Emilie Goguet, Cara H Olsen, William A Meyer, Sara Ansari, John H Powers, Tonia L Conner, Si'Ana A Coggins, Wei Wang, Richard Wang, Luca Illinik, Margaret Sanchez Edwards, Belinda M Jackson-Thompson, Monique Hollis-Perry, Gregory Wang, Yolanda Alcorta, Mimi A Wong, David Saunders, Roshila Mohammed, Bolatito Balogun, Priscilla Kobi, Lakeesha Kosh, Kimberly Bishop-Lilly, Regina Z Cer, Catherine E Arnold, Logan J Voegtly, Maren Fitzpatrick, Andrea E Luquette, Francisco Malagon, Orlando Ortega, Edward Parmelee, Julian Davies, Alyssa R Lindrose, Hannah Haines-Hull, Matthew S Moser, Emily C Samuels, Marana S Rekedal, Elizabeth K Graydon, Allison M W Malloy, David R Tribble, Timothy H Burgess, Wesley Campbell, Sara Robinson, Christopher C Broder, Robert J O'Connell, Carol D Weiss, Simon Pollett, Eric D Laing, Edward Mitre
INTRODUCTION: We sought to determine pre-infection correlates of protection against SARS-CoV-2 post-vaccine inzfections (PVI) acquired during the first Omicron wave in the United States. METHODS: Serum and saliva samples from 176 vaccinated adults were collected from October to December of 2021, immediately before the Omicron wave, and assessed for SARS-CoV-2 Spike-specific IgG and IgA binding antibodies (bAb). Sera were also assessed for bAb using commercial assays, and for neutralization activity against several SARS-CoV-2 variants...
2024: Frontiers in Immunology
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JOURNAL ARTICLE
William Zagrodzky, Julie Cooper, Christopher Joseph, Matthew Sackett, Jose Silva, Richard Kuk, Julia McHugh, Babette Brumback, Shirley Park, Robert Hayward, Taresh Taneja, Andrew Vu, Taylor Liu, Erik Kulstad, Andrew Kaplan, Archana Ramireddy, Samuel Omotoye
INTRODUCTION: Proactive esophageal cooling has been FDA cleared to reduce the likelihood of ablation-related esophageal injury resulting from radiofrequency (RF) cardiac ablation procedures. Data suggest that procedure times for RF pulmonary vein isolation (PVI) also decrease when proactive esophageal cooling is employed instead of luminal esophageal temperature (LET) monitoring. Reduced procedure times may allow increased electrophysiology (EP) lab throughput. We aimed to quantify the change in EP lab throughput of PVI cases after the introduction of proactive esophageal cooling...
April 3, 2024: Journal of Cardiovascular Electrophysiology
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JOURNAL ARTICLE
Astrid Paul Nordin, Mats Jensen-Urstad, Emmanouil Charitakis, Carina Carnlöf, Nikola Drca
INTRODUCTION: The presence of low-voltage zones (LVZs) in the left atrium (LA) is associated with the recurrence of atrial fibrillation (AF) following pulmonary vein isolation (PVI). However, there is variability and conflict in the data regarding predictors of LVZs as reported in previous studies. The objective of this study was to identify predictors for the presence of LVZs in a cohort of patients with persistent AF. METHODS: The study prospectively enrolled 439 patients with persistent AF who were scheduled for ablation...
April 1, 2024: Journal of Cardiovascular Electrophysiology
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JOURNAL ARTICLE
Ourania Kariki, Panagiotis Mililis, Athanasios Saplaouras, Stylianos Dragasis, Ilias G Patsiotis, Anastasios Chatziantoniou, Dimitrios Alexiou, Vasileios Cheilas, Konstantinos P Letsas, Michael Efremidis
BACKGROUND: High-power short duration(HPSD) and very high-power short duration(vHPSD-90W/4s) radiofrequency(RF) technology has reduced the procedure time of pulmonary vein isolation(PVI) using RF without compromising the efficacy of the technique. The current study compares the novel technology of HPSD/vHPSD with cryoablation(CRYO) in terms of efficacy, safety and procedure time in a cohort of symptomatic patients with paroxysmal atrial fibrillation(pAF). METHODS: This is a prospective non-randomized trial...
March 28, 2024: Hellenic Journal of Cardiology: HJC
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JOURNAL ARTICLE
Reşit Y Yilancioglu, Oğuzhan E Turan, Umut Inevi, Tamas Tahin, Gabor Szeplaki, Laszlo Geller, Emin E Özcan
BACKGROUND: Radiofrequency catheter ablation (RFCA) is a well-established treatment for atrial fibrillation (AF). Fluoroscopy, a widely used imaging method for RFCA, has significant implications for human health. Although no fluoroscopy or near-zero fluoroscopy strategies have gained popularity, they have limitations, such as long procedure times, additional equipment, and expertise. A simple and cost-effective radiation reduction method is needed for treating AF and is compatible with the daily workflow...
March 29, 2024: Minerva cardiology and angiology
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JOURNAL ARTICLE
Seda Sarihan, Tolga Koyuncu, Leyla Kazancioglu, Sule Batcik, Hizir Kazdal
The study aimed to assess the pleth variability index (PVI) in patients undergoing lumbar disc herniation surgery under general and spinal anesthesia, exploring its correlation with fluid responsiveness, position, and hemodynamic parameters. Methods: This prospective study included 88 ASA 1-2 patients, aged 18-65, undergoing 1-3 h elective lumbar disc herniation surgery. Patients in groups GA and SA were observed for demographic, operative, and hemodynamic parameters at specified time points. (3) Results: PVI values were comparable between the GA and SA groups...
February 25, 2024: Journal of Personalized Medicine
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JOURNAL ARTICLE
Ze Jin, Taehyun Hwang, Daehoon Kim, Byounghyun Lim, Oh-Seok Kwon, Sangbin Kim, Moon-Hyun Kim, Je-Wook Park, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Although pulmonary vein isolation (PVI) gaps and extrapulmonary vein triggers contribute to recurrence after atrial fibrillation (AF) ablation, their precise mechanisms remain unproven. Our study assessed the impact of PVI gaps on rhythm outcomes using a human AF digital twin. We included 50 patients (76.0% with persistent AF) who underwent catheter ablation with a realistic AF digital twin by integrating computed tomography and electroanatomical mapping. We evaluated the final rhythm status, including AF and atrial tachycardia (AT), across 600 AF episodes, considering factors including PVI level, PVI gap number, and pacing locations...
March 26, 2024: NPJ Digital Medicine
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JOURNAL ARTICLE
Tomonori Watanabe, Satoshi Hoshide, Hitoshi Hachiya, Yoshiyuki Yumita, Masafumi Sato, Tadayuki Mitama, Takafumi Okuyama, Hiroaki Watanabe, Ayako Yokota, Masashi Kamioka, Takahiro Komori, Hisaki Makimoto, Tomoyuki Kabutoya, Yasushi Imai, Kazuomi Kario
Lack of the typical nocturnal blood pressure (BP) fall, i.e non-dipper, has been known as a cardiovascular risk. However, the influence of non-dipper on atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) has been unclear. We investigated the clinical impact of non-dipping as evaluated by 24-hour ambulatory BP monitoring on the long-term outcome of AF recurrence post-PVI in 76 AF patients with a history of increased BP. The PVI procedure was successful in all 76 patients (mean age, 66±9years; antihypertensive medication, 89%; non-paroxysmal AF, 24%)...
March 26, 2024: Hypertension Research: Official Journal of the Japanese Society of Hypertension
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JOURNAL ARTICLE
Kotaro Ouchi, Toru Sakuma, Shunsuke Kisaki, Kenichi Tokutake, Teiichi Yamane, Hiroya Ojiri
Accurate measurement of the pulmonary vein dimension (PVD) is important for determining stenosis and efficacy following pulmonary vein isolation (PVI). Little is known about the quantitative evaluation of the impact of the cardiac cycle on pulmonary vein (PV) morphology before and after PVI. This study aims to investigate variations in the ostial size of the PV during the cardiac cycle before and after PVI and the effect of the cardiac cycle on PV stenosis and reduction rate using cardiac computed tomography (CT)...
March 25, 2024: Heart and Vessels
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JOURNAL ARTICLE
A Stanley, K A Van Bragt, V Obidigbo, B Vezi
BACKGROUND: Pulmonary vein isolation (PVI) with cryoballoon catheter ablation (CBA) is a well-established and widely adopted method for the treatment of patients with atrial fibrillation (AF) to prevent recurrences of AF. CBA adoption in South Africa (SA) and outcome data in SA patients are limited. OBJECTIVES: To evaluate real-world usage, safety and effectiveness of CBA in SA. METHODS: In this sub-analysis of the Cryo Global Registry, 81 participants with paroxysmal AF (PAF) and persistent AF (PsAF) were enrolled between 2017 and 2021 across two private SA hospitals...
March 18, 2024: South African Medical Journal
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JOURNAL ARTICLE
Hehua Zhang, Hua Zhang, Heng Lu, Yinjun Mao, Jianxing Chen
PURPOSE: The available data on the treatment strategy of pulsed field ablation (PFA) for patients with atrial fibrillation (AF) is limited. This study aims to provide a comparative analysis of the efficacy, safety, and procedural efficiency between PFA and cryoballoon ablation (CBA) for AF. METHODS: We conducted a comprehensive search of the EMBASE, PubMed, Cochrane Library, and ClinicalTrials.gov databases to identify trials comparing PFA with CBA for AF from their inception until December 2023...
March 25, 2024: Pacing and Clinical Electrophysiology: PACE
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JOURNAL ARTICLE
Medhat Farwati, Lorenzo Braghieri, Farah A Abdulhai, Marwan Dabbagh, Firas A Alkhalaileh, Arwa Younis, Chadi Tabaja, Amr Farwati, Mustapha Amin, Pasquale Santangeli, Hiroshi Nakagawa, Walid I Saliba, Mohamed Kanj, Thomas D Callahan, Mandeep Bhargava, Bryan Baranowski, John Rickard, Jakub Sroubek, Justin Lee, Patrick J Tchou, Oussama M Wazni, Ayman A Hussein
BACKGROUND: Data are lacking on patient-reported outcomes (PRO) following cryoballoon ablation (CBA) versus radiofrequency ablation (RFA). We sought to evaluate QoL and clinical outcomes of cryoballoon pulmonary vein isolation only (CRYO-PVI-ONLY) versus RFA with PVI and posterior wall isolation (RF-PVI+PWI) in a large prospective PRO registry. METHODS: Patients who underwent AF ablation (2013-2016) at our institution were enrolled in an automated, prospectively maintained PRO registry...
March 25, 2024: Pacing and Clinical Electrophysiology: PACE
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JOURNAL ARTICLE
Masamichi Yano, Yasuyuki Egami, Shodai Kawanami, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Masaki Tsuda, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masami Nishino
Pulmonary vein isolation (PVI) causes changes in P-wave parameters. However, the difference in changes in P-wave parameters including P-wave vector magnitude (Pvm) between radiofrequency catheter ablation (RFCA) and cryoballoon ablation (CBA) remains unknown. Paroxysmal atrial fibrillation (PAF) patients who underwent only PVI were enrolled. Pvm was calculated by the square root of the sum of the squared P-wave amplitude in leads II and V6 and one-half of the P-wave amplitude in V2. The patients were divided into two groups: RFCA and CBA...
March 22, 2024: American Journal of Cardiology
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JOURNAL ARTICLE
Marco Schiavone, Francesco Solimene, Massimo Moltrasio, Michela Casella, Stefano Bianchi, Saverio Iacopino, Antonio Rossillo, Vincenzo Schillaci, Gaetano Fassini, Paolo Compagnucci, Armando Salito, Pietro Rossi, Pasquale Filannino, Ruggero Maggio, Sakis Themistoklakis, Claudio Pandozi, Francesco Caprioglio, Maurizio Malacrida, Antonio Dello Russo, Claudio Tondo
INTRODUCTION: Limited data exist on pulsed-field ablation (PFA) in patients with persistent atrial fibrillation (PeAF) undergoing left atrial posterior wall isolation (LAPWI). METHODS: The Advanced TecHnologies For SuccEssful AblatioN of AF in Clinical Practice (ATHENA) prospective registry included consecutive patients referred for PeAF catheter ablation at 9 Italian centers, treated with the FARAPULSETM -PFA system. The primary efficacy and safety study endpoints were the acute LAPWI rate, freedom from arrhythmic recurrences and the incidence of major periprocedural complications...
March 22, 2024: Journal of Cardiovascular Electrophysiology
#35
REVIEW
Xindi Yue, Ling Zhou, Yahui Li, Chunxia Zhao
There has been a significant increase in the prevalence of atrial fibrillation (AF) over the past 30 years.3 Pulmonary vein isolation (PVI) is an effective treatment for atrial fibrillation (AF), but research investigations have shown that AF recurrence still occurs in a significant number of patients after ablation. Heart rhythm outcomes following catheter ablation are correlated with numerous clinical factors, and researchers developed predictive models by integrating risk factors to predict the risk of recurrence of atrial fibrillation...
March 20, 2024: Current Problems in Cardiology
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JOURNAL ARTICLE
Wayne R Hawley, Gregory D Morrow
Delay and probability discounting tasks are useful for understanding aspects of decision making. The current study, which employed a mixed-model design to assess discounting of penile-vaginal intercourse (PVI), was conducted online with male and female participants recruited from Prolific ( N = 300; mean age = 34.1 years). Results of the novel delay and probability discounting tasks indicated that as the delay to PVI increased, or as PVI became less certain to occur, participants were instead more likely to choose to receive oral sex, the reward initially indicated as less desirable...
March 22, 2024: Journal of Sex Research
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JOURNAL ARTICLE
Thomas Fink, Vanessa Sciacca, Flemming Nischik, Leonard Bergau, Denise Guckel, Mustapha El Hamriti, Moneeb Khalaph, Martin Braun, Stephan Winnik, Maxim Didenko, Guram Imnadze, Philipp Sommer, Christian Sohns
BACKGROUND AND AIMS: Pulmonary vein isolation (PVI) for catheter ablation of atrial fibrillation (AF) is a time-demanding procedure. High-power short-duration (HPSD) ablation protocols and high-density mapping catheters have recently been introduced to clinical practice. We investigated the impact of high-density mapping and HPSD ablation protocols on procedural timing, efficacy and safety by comparing different standardized setups. METHODS: Three electrophysiology laboratory setups were analyzed: 1) Circular catheter for mapping, ablation with 30/35W guided by ablation index (AI); 2) Pentaspline catheter for mapping, HPSD ablation with 50 W guided by AI; 3) Pentaspline catheter for mapping, HPSD ablation with 90W over 4 seconds using a novel ablation catheter...
March 22, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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JOURNAL ARTICLE
Gökhan Urhan, İsmail Demirel, Ahmet Deniz, Ahmet Aksu, Aysun Yıldız Altun, Esef Bolat, Azize Beştaş, Gülsüm Altuntaş
INTRODUCTION: Obesity increases the risk of morbidity and mortality during surgical procedures. Goal-directed fluid therapy (GDFT) is a new concept for perioperative fluid management that has been shown to improve patient prognosis. This study aimed to investigate the role of the Pleth Variability Index (PVI), systolic pressure variation (SPV), and pulse pressure variation (PPV) in maintaining tissue perfusion and renal function during GDFT management in patients undergoing laparoscopic sleeve gastrectomy (LSG)...
March 21, 2024: Obesity Surgery
#39
JOURNAL ARTICLE
C Y Maximilian Png, Laura T Boitano, Sunita D Srivastava, Abhisekh Mohapatra, Junaid Y Malek, Jordan R Stern, Matthew J Eagleton, Anahita Dua
INTRODUCTION: For patients receiving Procedural Sedation and Analgesia (PSA), patient cooperation is crucial as patients remain continuously aware of operating room activity and can be asked to perform tasks such as prolonged breath-holds. This survey aimed to collect information on patient compliance with on-table instructions and its relation to periprocedural outcomes from surgeons nationwide performing peripheral vascular interventions (PVI) under PSA. METHODS: A 9-question online survey was sent to 383 vascular surgeons (including both vascular surgery attendings and trainees) across the United States through REDCap from August 30 to September 21, 2021, with responses closed on October 30, 2021...
2024: JVS Vasc Insights
#40
REVIEW
Shohei Kataoka, Morio Shoda, Koichiro Ejima, Ken Kato, Kyoichiro Yazaki, Shun Hasegawa, Masayuki Sakai, Satoshi Higuchi, Daigo Yagishita, Junichi Yamaguchi
BACKGROUND AND OBJECTIVE: Treatment for atrial fibrillation (AF) has evolved significantly, with pulmonary vein isolation (PVI) becoming an established treatment. However, the outcomes following catheter ablation for persistent AF remain unsatisfactory. Hybrid catheter-surgical ablation has emerged as a therapeutic approach for persistent AF, combining the strengths of both interventions. The purpose of this narrative review is to comprehensively examine the current state of knowledge regarding hybrid ablation for AF...
February 29, 2024: Journal of Thoracic Disease
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