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JOURNAL ARTICLE
Thomas Kueffer, Robin Stettler, Jens Maurhofer, Antonio Madaffari, Anita Stefanova, Salik Ur Rehman Iqbal, Gregor Thalmann, Nikola A Kozhuharov, Oskar Galuszka, Helge Servatius, Andreas Haeberlin, Fabian Noti, Hildegard Tanner, Laurent Roten, Tobias Reichlin
BACKGROUND: Pulsed-field ablation (PFA) has shown promising data in terms of safety and procedural efficiency for pulmonary vein isolation (PVI), with similar long-term outcomes compared to radiofrequency ablation (RFA) and cryoballoon ablation (CBA) in patient with paroxysmal atrial fibrillation (AF) OBJECTIVE: To compare the procedural and long-term outcomes of patients with persistent AF undergoing PVI using PFA, CBA, or RFA. METHODS: Consecutive patients with persistent AF undergoing a first PVI with PFA, CBA, or RFA were included...
April 11, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#2
JOURNAL ARTICLE
Márton Boga, Gábor Orbán, Péter Perge, Zoltán Salló, Edit Tanai, Arnold Béla Ferencz, Patrik Tóth, Ferenc Komlósi, István Osztheimer, Klaudia Vivien Nagy, Béla Merkely, László Gellér, Nándor Szegedi
Background: Atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) is predominantly attributed to pulmonary vein reconnection (PVR). Predictors of AF recurrence have been widely studied; however, data are scarce on procedural parameters that predict chronic PVR. We aimed to study PVR rates and predictors of PVR. Methods: We retrospectively included 100 patients who underwent repeated ablation due to AF recurrence after initial PVI with the CARTO system. PVR was determined during the repeated procedure by electrophysiological evaluation, and initial procedural characteristics predicting PVR were studied, including adherence to the CLOSE protocol, use of high power, first-pass isolation (FPI), and baseline generator impedance (BGI)...
March 28, 2024: Journal of Clinical Medicine
#3
Łukasz Zarębski, Piotr Futyma, Yashvi Sethia, Marian Futyma, Piotr Kułakowski
In patients with atrial fibrillation (AF) recurrences after pulmonary vein isolation (PVI), concomitant treatment using anti arrhythmic drugs (AADs) can lead to clinical success. However, patients with atrioventricular (AV) block may not be good candidates for concomitant AAD therapy due to the risk of further worsening of conduction abnormalities. Cardioneuroablation (CNA), as an adjunct to PVI, may offer a solution to this problem. We present a case of a 74-year-old male with paroxysmal AF and first degree AV block in whom CNA following PVI led to PR normalization...
March 27, 2024: Healthcare (Basel, Switzerland)
#4
JOURNAL ARTICLE
Jacob Cleman, Juan G Sierra, Gaëlle Romain, Bella Capuano, Lindsey Scierka, Santiago Callegari, Francky Jacque, Poghni Peri-Okonny, Sameer Nagpal, Kim G Smolderen, Carlos Mena-Hurtado
OBJECTIVE: Comorbid chronic kidney disease (CKD) is associated with worse outcomes for patients with chronic limb-threatening ischemia (CLTI). However, comparative effectiveness data is limited for lower extremity bypass (LEB) vs. peripheral vascular intervention (PVI) in patients with CLTI and CKD. We aimed to evaluate 1) 30-day all-cause mortality and amputation and 2) 5-year all-cause mortality and amputation for LEB vs. PVI in patients with comorbid CKD. METHODS: Individuals undergoing LEB and PVI were queried from the Vascular Quality Initiative with Medicare claims-linked outcomes data...
April 10, 2024: Journal of Vascular Surgery
#5
JOURNAL ARTICLE
Teryn A Holeman, Cassidy Chester, Julie B Hales, Yue Zhang, Cali E Johnson, Benjamin S Brooke
OBJECTIVES: Society for Vascular Surgery guidelines recommend revascularization for patients with intermittent claudication (IC) if it can improve patient function and quality of life. However, it is still unclear if IC patients achieve a significant functional benefit from surgery compared to medical management alone. This study examines the relationship between IC treatment modality (operative vs. non-operative optimal medical management) and patient reported outcomes for physical function (PROMIS-PF) and satisfaction in social roles and activities (PROMIS-SA)...
April 10, 2024: Journal of Vascular Surgery
#6
JOURNAL ARTICLE
Randall A Bloch, Elisa Caron, Frank B Pomposelli, Scott G Prushik, Katie E Shean, Mark F Conrad
OBJECTIVE: Most surgeons employ an endovascular first approach to the treatment of peripheral arterial disease (PAD), but controversy remains regarding the ideal interventions for the management of isolated popliteal artery disease (IPAD). Indeed, there are a paucity of data that compare outcomes of popliteal stents versus other peripheral vascular interventions (PVI). The goal of this study was to evaluate outcomes of PVI in IPAD. METHODS: The Vascular Study Group of New England database was queried for all IPAD PVI performed for atherosclerotic occlusive disease from 2010-2021...
April 8, 2024: Journal of Vascular Surgery
#7
JOURNAL ARTICLE
Laurève Chollet, Salik Ur Rehman Iqbal, Severin Wittmer, Gregor Thalmann, Antonio Madaffari, Nikola Kozhuharov, Oskar Galuszka, Thomas Küffer, Christoph Gräni, Nicolas Brugger, Helge Servatius, Fabian Noti, Andreas Haeberlin, Laurent Roten, Hildegard Tanner, Tobias Reichlin
AIMS: Pulmonary vein isolation (PVI) is increasingly performed in patients with atrial fibrillation (AF). Both AF phenotype and left atrial (LA) volume have been shown to influence ablation outcome. The inter-relationship of the two is incompletely understood. We aimed to investigate the impact of AF phenotype vs. LA volume on outcome after PVI. METHODS AND RESULTS: In a retrospective analysis of a prospective registry of patients undergoing a first PVI, the association of AF phenotype and LA volume index (LAVI) was assessed as well as their impact on AF recurrence during follow-up...
March 30, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#8
JOURNAL ARTICLE
Ritwik Nigam, Alvarinho J Luis, Alexandre S Gagnon, Eric Vaz, Bruno Damásio, Mahender Kotha
Climate change poses a significant threat to coastal regions worldwide. This study presents and applies a modified Coastal Vulnerability Index (CVI) to assess coastal vulnerability at the village level, focusing on Canacona, a taluka in South Goa, India. It adapts the existing CVI methodology by incorporating additional variables to better represent the various dimensions of vulnerability, resulting in 21 variables split into a Physical Vulnerability Index (PVI) and a Social Vulnerability Index (SoVI). The results show spatial variability in coastal vulnerability across the studied villages, with Agonda and Nagercem-Chaudi found to be highly vulnerable and Loliem to be the least vulnerable...
April 19, 2024: IScience
#9
JOURNAL ARTICLE
Claudia Azzaro, Alessandro Meduri, Giovanni William Oliverio, Laura De Luca, Francesco Gazia, Francesco Franchina, Pasquale Aragona
Background: This study aimed to evaluate the safety and efficacy of povidone-iodine 0.6% (PVI) irrigation for preventing recurrence of stenosis after punctoplasty in patients with punctal and proximal canalicular stenosis treated using a venous catheter as a stent. Methods: Twenty patients were enrolled and divided into two groups. Group 1 received irrigation of 1 mL 0.6% PVI, while Group 2 received 1 mL of balanced salt solution (BSS). The patients underwent baseline, 15-, 30-, and 90-day assessments using the Ocular Surface Disease Index (OSDI) questionnaire, Symptoms Assessment in Dry Eye (SANDE), Schirmer I test, tear meniscus height (TMH), bulbar redness, meibography, and non-invasive breakup time (NIKBUT) through Keratograph 5M (Oculus, Germany)...
February 26, 2024: Journal of Clinical Medicine
#10
JOURNAL ARTICLE
Marco Schiavone, Gaetano Fassini, Massimo Moltrasio, Benedetta Majocchi, Fabrizio Tundo, Francesca Casati, Claudio Tondo
(1) Background/Objective Balloon-guided catheter ablation (CA) has emerged as an alternative option for atrial fibrillation (AF) management. The recent introduction of a novel-size adjustable second-generation cryoballoon (CB) system offers innovations, but clinical outcomes remain unexplored. This study aims to assess the acute performance of the POLARx FIT™ CB system in AFCA. (2) Methods: Consecutive patients undergoing AF ablation with the POLARx FIT™ CB system in our center were included. The primary outcome was the rate of 31 mm balloon-size utilization, with secondary outcomes including acute pulmonary vein isolation (PVI) rate, periprocedural complications, and in-hospital AF recurrences...
February 22, 2024: Journal of Clinical Medicine
#11
REVIEW
Timo Weimar, Mindy Vroomen
Establishing a successful and sustaining atrial fibrillation (AF) program should be current standard of care in cardiac surgery by providing not only sinus rhythm restoration but improving survival significantly. Recognition of AF as a serious cardiac disease impacting a considerable number of patients in terms of stroke, heart failure development and mortality is key when implementing a protocol to identify patients suitable for surgical ablation and a treatment standard according to the underlying pathology...
March 29, 2024: Annals of Cardiothoracic Surgery
#12
JOURNAL ARTICLE
Li Shu, Yi Lu, Shenghui Ma, Chunhui Liu, Zhejun Cai
A 55-year-old woman of I-IVC complicated with PLSVC underwent catheter ablation for atrial fibrillation through right jugular vein access. TSP was achieved by electrocautery and the J-tip guidewire with the help of deflectable sheath and ICE. After PVI, the CS-PLSVC and LA-PLSVC connections were ablated within PLSVC.
April 2024: Journal of Arrhythmia
#13
JOURNAL ARTICLE
Moyuru Hirata, Koichi Nagashima, Ryuta Watanabe, Yuji Wakamatsu, Shu Hirata, Sayaka Kurokawa, Yasuo Okumura
BACKGROUND: Although pulmonary vein isolation (PVI) for atrial fibrillation (AF) utilizing radiofrequency (RF) applications with a very high-power and short-duration (vHPSD) has shortened the procedure time, the determinants of pulmonary vein (PV) gaps in the first-pass PVI and acute PV reconnections are unclear. METHODS: An extensive encircling PVI was performed with the QDOT MICRO catheter with a vHPSD (90 W-4 s) in 30 patients with AF (19 men, 64 ± 10 years)...
April 2024: Journal of Arrhythmia
#14
JOURNAL ARTICLE
Satheesh Gunashekar, Ashutosh Kaushal, Ajit Kumar, Priyanka Gupta, Namrata Gupta, Pooja C S
BACKGROUND AND AIMS: Short-term hypotension after general anaesthesia can negatively impact surgical outcomes. This study compared the predictive potential of the pleth variability index (PVI), pulse pressure variability (PPV), and perfusion index (PI) for anaesthesia-induced hypotension. This study's primary objective was to evaluate the predictive potential of PI, PVI, and PPV for hypotension. METHODS: This observational study included 140 adult patients undergoing major abdominal surgery under general anaesthesia...
April 2024: Indian Journal of Anaesthesia
#15
Bharat K Kantharia, Zaw Win Tun, Arti N Shah
Pulmonary vein (PV) isolation (PVI) ablation as the first-line therapy for atrial fibrillation (AF) and repeat PVIs for patients who had symptomatic improvement with the index PVI but who develop AF recurrence are directed by practice guidelines. How many catheter ablation (CA) procedures constitute the definition of "multiple" ablations is not known. Whether atrial tachyarrhythmias (AF, atrial tachycardia [AT], atrial flutter [AFL]) that occur post-ablation are due entirely to the proarrhythmic effects of CA or a continuum of the arrhythmia spectrum from the underlying atriopathy is debatable...
March 2024: Journal of Innovations in Cardiac Rhythm Management
#16
JOURNAL ARTICLE
Vivek Y Reddy, Elad Anter, Petr Peichl, Gediminas Rackauskas, Jan Petru, Moritoshi Funasako, Jacob S Koruth, Germanas Marinskis, Mohit Turagam, Audrius Aidietis, Josef Kautzner, Andrea Natale, Petr Neuzil
BACKGROUND/AIMS: Pulsed field ablation (PFA) has significant advantages over conventional thermal ablation of atrial fibrillation (AF). This first-in-human, single-arm trial to treat paroxysmal AF (PAF) assessed the efficiency, safety, pulmonary vein isolation (PVI) durability and one-year clinical effectiveness of an 8-Fr, large-lattice, conformable single-shot PFA catheter together with a dedicated electroanatomical mapping system. METHODS: After rendering the PV anatomy, the PFA catheter delivered monopolar, biphasic pulse trains (5-6 secs per application; ∼4 applications per PV)...
April 8, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#17
JOURNAL ARTICLE
Yan Wang, Heng Li Lai, Qi Chen, Hao Liu, Qi Ming Liu, Wei Bin Huang, Yu Tao, Qingmei Xiong, Ning Zhou, Chunxia Zhao, Jie Qiu, Ziqin Xu, Dao Wen Wang
AIMS: A few studies have reported the effect and safety of pulsed field ablation (PFA) catheters for ablating atrial fibrillation (AF), which were mainly based on basket-shaped or flower-shaped designs. However, the clinical application of a circular-shaped multi-electrode catheter with magnetic sensors is very limited. To study the efficacy and safety of a PFA system in patients with paroxysmal AF using a circular-shaped multi-electrode catheter equipped with magnetic sensors for pulmonary vein isolation (PVI)...
March 30, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#18
JOURNAL ARTICLE
Paula Pinto, Cassius Iyad Ochoa Chaar
The use of atherectomy for peripheral vascular interventions (PVI) has increased exponentially and reached 18% of all PVI in the United States. The theoretical benefit on extensive arterial calcification relies on the concept of plaque modification and removal instead of displacement, as with other endovascular techniques. To date, there are no prospective studies comparing the different atherectomy technologies (directional, rotational, orbital, and laser). Moreover, most related prospective comparative studies have a small number of patients, and larger studies are single arm in patients with relatively mild to moderate disease burden...
April 5, 2024: Annals of Vascular Surgery
#19
JOURNAL ARTICLE
Peter Calvert, Ioanna Koniari, Mark T Mills, Reza Ashrafi, Richard Snowdon, Dhiraj Gupta, Vishal Luther
INTRODUCTION: Pulmonary vein isolation (PVI) is often performed under general anaesthesia (GA) or deep sedation. Anaesthetic availability is limited in many centers, and deep sedation is prohibited in some countries without anaesthetic support. Very high-power short duration (vHPSD-90W/4 s) PVI using the Q-Dot catheter is generally well tolerated under mild conscious sedation (MCS) though an understanding of catheter stability and long-term effectiveness is lacking. We analyzed lesion metrics and 12-month freedom from atrial arrythmia with this approach...
April 3, 2024: Journal of Cardiovascular Electrophysiology
#20
JOURNAL ARTICLE
Emilie Goguet, Cara H Olsen, William A Meyer, Sara Ansari, John H Powers, Tonia L Conner, Si'Ana A Coggins, Wei Wang, Richard Wang, Luca Illinik, Margaret Sanchez Edwards, Belinda M Jackson-Thompson, Monique Hollis-Perry, Gregory Wang, Yolanda Alcorta, Mimi A Wong, David Saunders, Roshila Mohammed, Bolatito Balogun, Priscilla Kobi, Lakeesha Kosh, Kimberly Bishop-Lilly, Regina Z Cer, Catherine E Arnold, Logan J Voegtly, Maren Fitzpatrick, Andrea E Luquette, Francisco Malagon, Orlando Ortega, Edward Parmelee, Julian Davies, Alyssa R Lindrose, Hannah Haines-Hull, Matthew S Moser, Emily C Samuels, Marana S Rekedal, Elizabeth K Graydon, Allison M W Malloy, David R Tribble, Timothy H Burgess, Wesley Campbell, Sara Robinson, Christopher C Broder, Robert J O'Connell, Carol D Weiss, Simon Pollett, Eric D Laing, Edward Mitre
INTRODUCTION: We sought to determine pre-infection correlates of protection against SARS-CoV-2 post-vaccine inzfections (PVI) acquired during the first Omicron wave in the United States. METHODS: Serum and saliva samples from 176 vaccinated adults were collected from October to December of 2021, immediately before the Omicron wave, and assessed for SARS-CoV-2 Spike-specific IgG and IgA binding antibodies (bAb). Sera were also assessed for bAb using commercial assays, and for neutralization activity against several SARS-CoV-2 variants...
2024: Frontiers in Immunology
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