Kate M Bermingham, Inbar Linenberg, Lorenzo Polidori, Francesco Asnicar, Alberto Arrè, Jonathan Wolf, Fatema Badri, Hannah Bernard, Joan Capdevila, William J Bulsiewicz, Christopher D Gardner, Jose M Ordovas, Richard Davies, George Hadjigeorgiou, Wendy L Hall, Linda M Delahanty, Ana M Valdes, Nicola Segata, Tim D Spector, Sarah E Berry
Large variability exists in people's responses to foods. However, the efficacy of personalized dietary advice for health remains understudied. We compared a personalized dietary program (PDP) versus general advice (control) on cardiometabolic health using a randomized clinical trial. The PDP used food characteristics, individual postprandial glucose and triglyceride (TG) responses to foods, microbiomes and health history, to produce personalized food scores in an 18-week app-based program. The control group received standard care dietary advice (US Department of Agriculture Guidelines for Americans, 2020-2025) using online resources, check-ins, video lessons and a leaflet...
May 8, 2024: Nature Medicine