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https://www.readbyqxmd.com/read/29220496/the-duration-of-influenza-vaccine-effectiveness-a-systematic-review-meta-analysis-and-meta-regression-of-test-negative-design-case-control-studies
#1
Barnaby Young, Sapna Sadarangani, Lili Jiang, Annelies Wilder-Smith, Mark I-Cheng Chen
Background: Whether influenza vaccination offers protection for the duration of an influenza season has recently been questioned following analysis of data from test-negative design (TND) case-control studies. Method: The published literature was systematically reviewed to identify TND studies which estimated change in vaccine effectiveness (VE) with time since vaccination. Results: Fourteen studies were identified through the literature search as meeting eligibility criteria...
December 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29215770/molecular-ecology-of-listeria-spp-salmonella-escherichia-coli-o157-h7-and-non-o157-shiga-toxin-producing-escherichia-coli-in-pristine-natural-environments-in-northern-colorado
#2
Christina A Ahlstrom, Clyde S Manuel, Henk C Den Bakker, Martin Wiedmann, Kendra K Nightingale
AIMS: Molecular subtyping is commonly used in foodborne disease surveillance and microbial source tracking. There is a knowledge gap regarding the molecular ecology of foodborne pathogens in non-food associated environments. The objective of this study was to isolate and subtype foodborne pathogens from pristine natural environments with minimal anthropogenic inputs. MATERIALS AND RESULTS: Five locations (wilderness areas) in Northern Colorado were sampled during the spring, summer, and fall over a two-year period...
December 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29211951/a-double-blinded-randomized-study-evaluating-the-in-vivo-effects-of-a-novel-dental-gel-on-enamel-surface-microstructure-and-microhardness
#3
Afarin Golabgir Anbarani, Jessica Ho, Thinh Hung Vu, Ali Forghany, Tracie Lam, Erisa Khashai, Karan Sahni, Thair Takesh, Petra Wilder-Smith
OBJECTIVES: The objective of this study was to evaluate the in vivo effects of a 2.6% edathamil gel (Livionex® Dental Gel) on surface microhardness and microstructure in 180 pre-eroded enamel chips. METHODS: This was a double-blind, randomized study. Two enamel chips each were cut from 90 healthy sterilized extracted teeth. One chip from each pair underwent microhardness testing and scanning electron microscopy (SEM) to establish baselines. The remaining 90 samples were demineralized, and then mounted onto intra-oral retainers worn by nine subjects, with five chips mounted on each retainer for each of the two study arms...
September 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/29190718/investigating-the-validity-of-the-dn4-in-a-consecutive-population-of-patients-with-chronic-pain
#4
Hans Timmerman, Monique A H Steegers, Frank J P M Huygen, Jelle J Goeman, Nick T van Dasselaar, Marcel J Schenkels, Oliver H G Wilder-Smith, André P Wolff, Kris C P Vissers
Neuropathic pain is clinically described as pain caused by a lesion or disease of the somatosensory nervous system. The aim of this study was to assess the validity of the Dutch version of the DN4, in a cross-sectional multicentre design, as a screening tool for detecting a neuropathic pain component in a large consecutive, not pre-stratified on basis of the target outcome, population of patients with chronic pain. Patients' pain was classified by two independent (pain-)physicians as the gold standard. The analysis was initially performed on the outcomes of those patients (n = 228 out of 291) in whom both physicians agreed in their pain classification...
2017: PloS One
https://www.readbyqxmd.com/read/29186021/an-efficient-audio-coding-scheme-for-quantitative-and-qualitative-large-scale-acoustic-monitoring-using-the-sensor-grid-approach
#5
Félix Gontier, Mathieu Lagrange, Pierre Aumond, Arnaud Can, Catherine Lavandier
The spreading of urban areas and the growth of human population worldwide raise societal and environmental concerns. To better address these concerns, the monitoring of the acoustic environment in urban as well as rural or wilderness areas is an important matter. Building on the recent development of low cost hardware acoustic sensors, we propose in this paper to consider a sensor grid approach to tackle this issue. In this kind of approach, the crucial question is the nature of the data that are transmitted from the sensors to the processing and archival servers...
November 29, 2017: Sensors
https://www.readbyqxmd.com/read/29182662/threats-from-urban-expansion-agricultural-transformation-and-forest-loss-on-global-conservation-priority-areas
#6
Victoria Veach, Atte Moilanen, Enrico Di Minin
Including threats in spatial conservation prioritization helps identify areas for conservation actions where biodiversity is at imminent risk of extinction. At the global level, an important limitation when identifying spatial priorities for conservation actions is the lack of information on the spatial distribution of threats. Here, we identify spatial conservation priorities under three prominent threats to biodiversity (residential and commercial development, agricultural expansion, and forest loss), which are primary drivers of habitat loss and threaten the persistence of the highest number of species in the International Union for the Conservation of Nature (IUCN) Red List, and for which spatial data is available...
2017: PloS One
https://www.readbyqxmd.com/read/29158664/impact-of-baseline-blood-pressure-on-the-magnitude-of-blood-pressure-lowering-by-nifedipine-gastrointestinal-therapeutic-system-refreshing-the-wilder-s-principle
#7
Haijuan Hu, Jidong Zhang, Yan Wang, Zejun Tian, Demin Liu, Guangming Zhang, Guoqiang Gu, Hongmei Zheng, Ruiqin Xie, Wei Cui
Background: The objective of the study was to investigate the relationship between baseline blood pressure (BP) and the magnitude of BP reduction in patients with essential hypertension treated with nifedipine gastrointestinal therapeutic system (NGTS). Methods and patients: One hundred and thirty-eight patients with essential hypertension were enrolled in this prospective, single-arm, open-label study. NGTS was administered for 24 weeks to achieve target BP of 140/90 mmHg...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29153978/the-endometria-of-women-with-endometriosis-exhibit-dysfunctional-expression-of-complement-regulatory-proteins-during-the-mid-secretory-phase
#8
Wilder A Palomino, Chandrakant Tayade, Felipe Argandoña, Luigi Devoto, Steven L Young, Bruce A Lessey
The control of complement activation within embryo-endometrium environment is critical for embryo survival. Cell evasion from complement attack requires interaction of complement regulatory proteins (CRPs) with cell adhesion αvβ3 integrin. We aim to compare the expression of CRPs in endometria of women with and without endometriosis and to examine the molecular interaction of decay accelerating factor (DAF) with αvβ3 integrin. Endometrial expression of Membrane cofactor protein (CD46), Decay accelerating factor (DAF), Membrane attack complex inhibitory factor (CD59) and β3 integrin subunit were determined through menstrual cycle by immunohistochemistry...
October 27, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29146853/genome-sequences-of-four-subcluster-l2-mycobacterium-phages-finemlucis-miley16-wilder-and-zakai
#9
Christopher D Herren, Alexandra Peister, Timothy S Breton, Maggie S Hill, Marcy S Anderson, Adeline W Chang, Sydney B Klein, Mackenzie M Thornton, Stacy J Vars, Kasey E Wagner, Paige L Wiebe, Thomas G Williams, Coraima P Yanez, Jasanta M Ackles, Darius Artis, Ryan J Brazier, Ronald J Bryant, Kerel O Callwood, Isaiah H Carter, Cameron L DeBose, Christian D Edwards, Isaiah C Ezemba, Renshal R Joaquin, Zakai M Meghoo-Peddie, Ziha G Meghoo-Peddie, Ryan W Moore, Christopher E Smith, Adam J Turner, Raymond L Vorters, Jeffrey J Wider, Liesel L Krout, Mia S Comis, Madison J Davick, Eli E Michaud, Bailey E Shevenell, Sarah E Stanley, Chelsey I Frank, Jacob R Montgomery, Lawrence S Blumer, Jean A Doty, Martha Smith-Caldas, Welkin H Pope, Steven G Cresawn, Daniel A Russell, Rebecca A Garlena, Deborah Jacobs-Sera, Graham F Hatfull
Four subcluster L2 mycobacteriophages, Finemlucis, Miley16, Wilder, and Zakai, that infect Mycobacterium smegmatis mc(2)155 were isolated. The four phages are closely related to each other and code for 12 to 14 tRNAs and 130 to 132 putative protein-coding genes, including tyrosine integrases, cro, immunity repressors, and excise genes involved in the establishment of lysogeny.
November 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29145453/the-antiviral-drug-tenofovir-an-inhibitor-of-pannexin-1-mediated-atp-release-prevents-liver-and-skin-fibrosis-by-downregulating-adenosine-levels-in-the-liver-and-skin
#10
Jessica L Feig, Aranzazu Mediero, Carmen Corciulo, Hailing Liu, Jin Zhang, Miguel Perez-Aso, Laura Picard, Tuere Wilder, Bruce Cronstein
BACKGROUND: Fibrosing diseases are a leading cause of morbidity and mortality worldwide and, therefore, there is a need for safe and effective antifibrotic therapies. Adenosine, generated extracellularly by the dephosphorylation of adenine nucleotides, ligates specific receptors which play a critical role in development of hepatic and dermal fibrosis. Results of recent clinical trials indicate that tenofovir, a widely used antiviral agent, reverses hepatic fibrosis/cirrhosis in patients with chronic hepatitis B infection...
2017: PloS One
https://www.readbyqxmd.com/read/29133809/stromatolites-on-the-rise-in-peat-bound-karstic-wetlands
#11
Bernadette C Proemse, Rolan S Eberhard, Chris Sharples, John P Bowman, Karen Richards, Michael Comfort, Leon A Barmuta
Stromatolites are the oldest evidence for life on Earth, but modern living examples are rare and predominantly occur in shallow marine or (hyper-) saline lacustrine environments, subject to exotic physico-chemical conditions. Here we report the discovery of living freshwater stromatolites in cool-temperate karstic wetlands in the Giblin River catchment of the UNESCO-listed Tasmanian Wilderness World Heritage Area, Australia. These stromatolites colonize the slopes of karstic spring mounds which create mildly alkaline (pH of 7...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29127938/caregiver-feeding-practices-and-weight-status-among-african-american-adolescents-the-jackson-heart-kids-pilot-study
#12
E Thomaseo Burton, Tanganyika Wilder, Bettina M Beech, Marino A Bruce
Adolescence is a stage in the life course during which youth become more autonomous in their health behaviors. Overweight and obesity during this developmental period are associated with short- and long-term physical and emotional morbidity, and African American youth are at pronounced risk for these health outcomes. The style of parenting employed by caregivers influences health behaviors in children, though the persistence of this influence into adolescence is not clear. This study examined associations among caregiver feeding practices, body mass index z-score (zBMI), and waist circumference (WC) in a cohort of 212 African American adolescents (50...
November 6, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/29122110/survival-from-prolonged-cardiac-arrest-in-the-wilderness
#13
Richard B Utarnachitt, Ryan Mason
No abstract text is available yet for this article.
November 2017: Air Medical Journal
https://www.readbyqxmd.com/read/29119445/guidelines-for-bacteriophage-product-certification
#14
Alan Fauconnier
Following decades in the wilderness, bacteriophage therapy is now appearing as a credible antimicrobial strategy. However, this reemerging therapy does not rekindle without raising sensitive regulatory concerns. Indeed, whereas the European regulatory framework has been basically implemented to tackle ready-to-use pharmaceuticals produced on a large scale, bacteriophage therapy relies on a dynamic approach requiring a regulation on personalized medicine, nonexistent at present. Because of this, no guideline are currently available for addressing the scientific and regulatory issues specifically related to phage therapy medicinal products (PTMP)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29118153/the-impact-of-leadership-and-research-on-decision-making
#15
EDITORIAL
Rebecca S Wilder
No abstract text is available yet for this article.
December 2016: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29118144/growth-change%C3%A2-and-gratitude
#16
EDITORIAL
Rebecca S Wilder
No abstract text is available yet for this article.
February 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29118065/rejection-hurts
#17
EDITORIAL
Rebecca S Wilder
No abstract text is available yet for this article.
June 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29098112/beyond-wilderness-towards-an-anthropology-of-infrastructure-and-the-built-environment-in-the-russian-north
#18
Peter Schweitzer, Olga Povoroznyuk, Sigrid Schiesser
Public and academic discourses about the Polar regions typically focus on the so-called natural environment. While, these discourses and inquiries continue to be relevant, the current article asks the question how to conceptualize the on-going industrial and infrastructural build-up of the Arctic. Acknowledging that the "built environment" is not an invention of modernity, the article nevertheless focuses on large-scale infrastructural projects of the twentieth century, which marks a watershed of industrial and infrastructural development in the north...
January 2, 2017: Polar Journal
https://www.readbyqxmd.com/read/29090405/predicting-occupancy-and-abundance-by-niche-position-niche-breadth-and-body-size-in-stream-organisms
#19
Mariana P Rocha, Luis M Bini, Tadeu Siqueira, Jan Hjort, Mira Grönroos, Marja Lindholm, Satu-Maaria Karjalainen, Jani Heino
The regional occupancy and local abundance of species are thought to be strongly correlated to their body size, niche breadth and niche position. The strength of the relationships among these variables can also differ between different organismal groups. Here, we analyzed data on stream diatoms and insects from a high-latitude drainage basin to investigate these relationships. To generate measures of niche position and niche breadth for each species, we used sets of local environmental and catchment variables separately, applying the outlying mean index analysis...
October 31, 2017: Oecologia
https://www.readbyqxmd.com/read/29076417/epilepsy-and-neurosurgery-historical-highlights
#20
Marianna Karamanou, Gregory Tsoucalas, Marios Themistocleous, Dimitrios Giakoumettis, George Stranjalis, George Androutsos
Epilepsy has been known since antiquity and trepanation has been documented as a therapeutic option. The Greek born physician Aretaeus of Cappadocia (2nd century BC) was the first to recommend trepanation for the treatment of refractory epilepsy to drugs, pointing out the efficacy of the method. Trepanation was practiced throughout the Middle Ages, as it is proved by the book of "Quattuor Magistri" and during Renaissance as well. In 19th century, Sir Victor Alexander Horsley (1857-1916), combining analysis of clinical presentation with cortical stimulation, performed a series of craniotomies for the treatment of epilepsy...
October 24, 2017: Current Pharmaceutical Design
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