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https://www.readbyqxmd.com/read/28813178/centriole-biogenesis-from-identifying-the-characters-to-understanding-the-plot
#1
Niccolò Banterle, Pierre Gönczy
The centriole is a beautiful microtubule-based organelle that is critical for the proper execution of many fundamental cellular processes, including polarity, motility, and division. Centriole biogenesis, the making of this miniature architectural wonder, has emerged as an exemplary model to dissect the mechanisms governing the assembly of a eukaryotic organelle. Centriole biogenesis relies on a set of core proteins whose contributions to the assembly process have begun to be elucidated. Here, we review current knowledge regarding the mechanisms by which these core characters function in an orderly fashion to assemble the centriole...
August 16, 2017: Annual Review of Cell and Developmental Biology
https://www.readbyqxmd.com/read/28810414/body-image-and-sexual-orientation-the-experiences-of-lesbian-and-bisexual-women
#2
Marie L Smith, Elina Telford, Jeremy J Tree
Western cultures promote a thin and curvaceous ideal body size that most women find difficult to achieve by healthy measures, resulting in poor body image and increased risk for eating pathology. Research focusing on body image in lesbian and bisexual women has yielded inconsistent results. In total, 11 lesbian and bisexual women were interviewed regarding their experiences with body image. Interpretative phenomenological analysis revealed that these women experienced similar mainstream pressures to conform to a thin body ideal...
February 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28807594/thyroid-hormone-receptor-beta-agonist-gc-1-inhibits-met-%C3%AE-catenin-driven-hepatocellular-cancer
#3
Elisabetta Puliga, Qian Min, Junyan Tao, Rong Zhang, Tirthadipa Pradhan-Sundd, Minakshi Poddar, Sucha Singh, Amedeo Columbano, Jinming Yu, Satdarshan P Monga
The thyromimetic agent GC-1 induces hepatocyte proliferation via Wnt/β-catenin signaling and may promoting regeneration in both acute and chronic liver insufficiencies. However, β-catenin activation particularly due to mutations in CTNNB1 is seen in a subset of hepatocellular carcinomas (HCC). Thus, it will be critical to address any effect of GC-1 on HCC growth and development, before its use can be advocated to stimulate regeneration in chronic liver diseases. In the current study, we first examine the effect of GC-1 on β-catenin-TCF4 activity in HCC cell lines harboring wild-type or mutated-CTNNB1...
August 11, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28805247/beauty-in-the-blink-of-an-eye-the-time-course-of-aesthetic-experiences
#4
San Verhavert, Johan Wagemans, M Dorothee Augustin
Under normal circumstances, perception runs very fast and seemingly automatic. In just a few ms, we go from sensory features to perceiving objects. This fast time course does not only apply to general perceptual aspects but also to what we call higher-level judgements. Inspired by the study on 'very first impressions' by Bar, Neta, and Linz (2006, Emotion, 6, 269) the current research examined the speed and time course of three aspects of the aesthetic experience, namely beauty, specialness, and impressiveness...
August 14, 2017: British Journal of Psychology
https://www.readbyqxmd.com/read/28799070/the-beauty-of-sensory-ecology
#5
Fernando Otálora-Luna, Elis Aldana
Sensory ecology is a discipline that focuses on how living creatures use information to survive, but not to live. By trans-defining the orthodox concept of sensory ecology, a serious heterodox question arises: how do organisms use their senses to live, i.e. to enjoy or suffer life? To respond to such a query the objective (time-independent) and emotional (non-rational) meaning of symbols must be revealed. Our program is distinct from both the neo-Darwinian and the classical ecological perspective because it does not focus on survival values of phenotypes and their functions, but asks for the aesthetic effect of biological structures and their symbolism...
August 10, 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/28791577/-barbie-doll-syndrome-a-case-report-of-body-dysmorphic-disorder
#6
Maria Gruber, Rebecca Jahn, Karin Stolba, Michael Ossege
BACKGROUND: This case report aims to present a 37-year-old women striving to shape her body like a Barbie doll of which she has been fascinated since childhood. She could hardly tolerate any deviation from this beauty ideal. She has been admitted to the psychosomatic ward due to an eating disorder. METHODS: The ICD-10 and DSM-5 criteria were established for axis I disorders and the German version of the SCID II interview (for DSM-4) was applied for axis II disorders...
August 8, 2017: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/28791142/using-deep-learning-to-quantify-the-beauty-of-outdoor-places
#7
Chanuki Illushka Seresinhe, Tobias Preis, Helen Susannah Moat
Beautiful outdoor locations are protected by governments and have recently been shown to be associated with better health. But what makes an outdoor space beautiful? Does a beautiful outdoor location differ from an outdoor location that is simply natural? Here, we explore whether ratings of over 200 000 images of Great Britain from the online game Scenic-Or-Not, combined with hundreds of image features extracted using the Places Convolutional Neural Network, might help us understand what beautiful outdoor spaces are composed of...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28790238/-early-postoperative-hemodynamics-of-mitral-valvuloplasty-using-colvin-galloway-future-band
#8
Ryosuke Funahashi, Yukikatsu Okada, Takashi Muro, Hitoshi Inanami, Tomoyuki Takemoto
The Colvin-Galloway( CG) Future annuloplasty band is a new semirigid partial band, which was introduced in 2012 in Japan. A total of 60 consecutive patients who underwent mitral valve repair with the CG Future Band were assessed by echocardiography in terms of residual mitral regurgitation and diastolic mitral function postoperatively. Intraoperative 3-dimensional echocardiography beautifully demonstrated the physiological change of the aortic curtain during the cardiac cycle. 30 mm was used in 18 patients, 32 mm in 17, 28 mm in 15, 34 mm in 5, 36 mm in 2, and 26 mm in 2...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28789502/-pay-attention-to-the-standardized-application-of-new-techniques-in-surgical-treatment-of-thyroid-disease
#9
W Tian, H Q Xi, B Wang
The continuous development and application of new technology in thyroid surgery has promoted the rapid improvement of thyroid surgery. New technology in the field of thyroid surgery has developed rapidly. The application of neural monitoring technology has enabled the thyroid surgery to enter an accurate era. Imtraoperative neuromonitoring and continuous intraoperative neuromonitoring have made the recurrent laryngeal nerve protection more secure. Nano-carbon parathyroid gland negative imaging technology could identify parathyroid gland more precise...
August 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28787487/the-beautiful-brain-and-the-influence-of-santiago-ram%C3%A3-n-y-cajal-on-medicine
#10
Apostolos P Georgopoulos, Angeliki Georgopoulos
No abstract text is available yet for this article.
August 8, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28782762/the-rsc-faraday-prize-lecture-of-1989-on-platinum
#11
John Meurig Thomas
In 1861, Michael Faraday gave one of his last Friday Evening Discourses at the Royal Institution of Great Britain, London, on platinum, which he described as "this beautiful, magnificent and valuable metal". More than a hundred and twenty years later (in 1989), the author re-enacted, at the Royal Institution, many of the demonstrations that Faraday carried out in his memorable Discourse. This article outlines many of Faraday's views on, and experiments with, platinum. It also describes the continuing importance and utilization of platinum, both as perceived in 1989 and from present perspectives...
August 7, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28780881/-phytoestrogens-in-the-treatment-of-menopause
#12
Júlia Remport, Anna Blázovics
In previous centuries many women did not even live until their menopause years due to poor economic conditions, deficiencies of medicine, epidemics and wars. Nowadays in the developed countries, people live until they are 75-80 years old, and with the expansion of average age, the number of people affected by menopause and the years spent in that state increase. Nowadays women spend one third of their lives in the menopausal stage. The only effective way to treat unpleasant symptoms for centuries was with the use of herbs, and the knowledge about them spread through oral tradition...
August 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28772308/association-of-frontal-and-lateral-facial-attractiveness
#13
Jeffrey T Gu, David Avilla, Zlatko Devcic, Koohyar Karimi, Brian J F Wong
Importance: Despite the large number of studies focused on defining frontal or lateral facial attractiveness, no reports have examined whether a significant association between frontal and lateral facial attractiveness exists. Objectives: To examine the association between frontal and lateral facial attractiveness and to identify anatomical features that may influence discordance between frontal and lateral facial beauty. Design, Setting, and Participants: Paired frontal and lateral facial synthetic images of 240 white women (age range, 18-25 years) were evaluated from September 30, 2004, to September 29, 2008, using an internet-based focus group (n = 600) on an attractiveness Likert scale of 1 to 10, with 1 being least attractive and 10 being most attractive...
August 3, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28771895/an-evaluation-of-the-effect-of-periodontal-biotype-on-inter-dental-papilla-proportions-distances-between-facial-and-palatal-papillae-in-the-maxillary-anterior-dentition
#14
Arshia Jameel Ahmed, Ashish S Nichani, Ranganath Venugopal
PURPOSE: Gingival esthetics are an essential segment of facial beauty. The aim of the present study was to clinically assess the impact of periodontal biotype (PB), the length between the base of interproximal contact area and the interproximal bone crest (CP-BC), the distance between the facial and palatal papillae (DFPP), and papillary proportions (PP) on the presence of interdental papillae (PIP). MATERIALS AND METHODS: 80 patients aged 18 to 60 years were recruited for study...
August 3, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28769082/neural-substrates-of-embodied-natural-beauty-and-social-endowed-beauty-an-fmri-study
#15
Wei Zhang, Xianyou He, Siyan Lai, Juan Wan, Shuxian Lai, Xueru Zhao, Darong Li
What are the neural mechanisms underlying beauty based on objective parameters and beauty based on subjective social construction? This study scanned participants with fMRI while they performed aesthetic judgments on concrete pictographs and abstract oracle bone scripts. Behavioral results showed both pictographs and oracle bone scripts were judged to be more beautiful when they referred to beautiful objects and positive social meanings, respectively. Imaging results revealed regions associated with perceptual, cognitive, emotional and reward processing were commonly activated both in beautiful judgments of pictographs and oracle bone scripts...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28768232/phase-transition-analysis-of-v-shaped-liquid-crystal-combined-temperature-dependent-ftir-and-density-functional-theory-approach
#16
Swapnil Singh, Harshita Singh, T Karthick, Poonam Tandon, Veena Prasad
Temperature-dependent Fourier transform infrared spectroscopy (FTIR) combined with density functional theory (DFT) is employed to study the mechanism of phase transitions of V-shaped bent-core liquid crystal. Since it has a large number of flexible bonds, one-dimensional potential energy scan (PES) was performed on the flexible bonds and predicted the most stable conformer I. A detailed analysis of vibrational normal modes of conformer I have been done on the basis of potential energy distribution. The good agreement between the calculated spectrum of conformer I and observed FTIR spectrum at room temperature validates our theoretical structure model...
July 25, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28764007/formation-and-emission-of-linalool-in-tea-camellia-sinensis-leaves-infested-by-tea-green-leafhopper-empoasca-matsumurasca-onukii-matsuda
#17
Xin Mei, Xiaoyu Liu, Ying Zhou, Xiaoqin Wang, Lanting Zeng, Xiumin Fu, Jianlong Li, Jinchi Tang, Fang Dong, Ziyin Yang
Famous oolong tea (Oriental Beauty), which is manufactured by tea leaves (Camellia sinensis) infected with tea green leafhoppers, contains characteristic volatile monoterpenes derived from linalool. This study aimed to determine the formation mechanism of linalool in tea exposed to tea green leafhopper attack. The tea green leafhopper responsible for inducing the production of characteristic volatiles was identified as Empoasca (Matsumurasca) onukii Matsuda. E. (M.) onukii attack significantly induced the emission of linalool from tea leaves (p<0...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28758181/how-cranial-shapes-led-to-contemporary-ethnic-classification-a-historical-view
#18
Deniz Belen
In medical literature various ethnic terms, like Caucasian or Mongolian, are sporadically cited for indicating the relationship between certain disorders and geographical origin of individuals. Few of scientists recognize that those definitions are stemmed from a medical thesis written by the German physician Johann Friedrich Blumenbach in 1775. Through considering cranial shapes, Blumenbach proposed five race varieties including the Caucasian, the Mongolian, the Malayan, the Ethiopian, and the American. While he favored only beauty his contemporaries reclaimed an intellectuality arrangement among those race types and gave the highest credibility to Caucasian, which therefore, besides defining an ethnicity, has conveyed a discriminatory meaning...
June 20, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28749358/a-new-neural-dynamic-classification-algorithm
#19
Mohammad Hossein Rafiei, Hojjat Adeli
The keys for the development of an effective classification algorithm are: 1) discovering feature spaces with large margins between clusters and close proximity of the classmates and 2) discovering the smallest number of the features to perform accurate classification. In this paper, a new supervised classification algorithm, called neural dynamic classification (NDC), is presented with the goal of: 1) discovering the most effective feature spaces and 2) finding the optimum number of features required for accurate classification using the patented robust neural dynamic optimization model of Adeli and Park...
July 25, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28746765/the-spectacular-garden-where-might-de-extinction-lead
#20
Gregory E Kaebnick
The emergence of de-extinction is a study in technological optimism. What has already been accomplished in recovering ancient genomes, recreating them, and reproducing animals with engineered genomes is amazing but also has a long ways to go to achieve "de-extinction" as most people would understand that term. Still, with some caveats in place, creating a functional replacement for an extinct species may sometimes be doable, and given the right goals, might sometimes make sense. The International Union for Conservation of Nature guidelines for de-extinction do a reasonable job of keeping the caveats in place and clarifying the goals...
July 2017: Hastings Center Report
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